Human IFN-alpha Serum Sample ELISA Kit

Name: Human IFN-alpha Serum Sample ELISA Kit
Brand: R&D Systems
SKU: 41110-1
Price: 775 USD

Catalog #: 41110-1
4 Citations Datasheet / COA / SDS

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Product Details

Citations (4)

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Summary Product Datasheets Preparation and Storage Background Related Research Areas

Human IFN-alpha Serum Sample ELISA Kit Summary

Assay Length

3.25 hours

Sample Type & Volume Required Per Well

Cell Culture Supernates (100 uL), Serum (100 uL), Plasma (100 uL)

Sensitivity

12.5 pg/mL

Assay Range

12.5 - 1,000 pg/mL (Cell Culture Supernates, Serum, Plasma)

Specificity

Human IFN-alpha

Cross-reactivity

< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.

Interference

No significant interference observed with available related molecules.

Product Summary

Product Datasheets

Product Datasheet

COA

SDS

Preparation and Storage

Shipping

The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Long Name:

Interferon alpha

Entrez Gene IDs:

3440 (Human)

Alternate Names:

IFNA; IFNA2; IFNA2b; IFNalpha; IFN-alpha; IFN-alphaA; INFA2; interferon alpha 2; LeIF D

Related Research Areas

Citations for Human IFN-alpha Serum Sample ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

4 Citations: Showing 1 - 4
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STAG2 deficiency induces interferon responses via cGAS-STING pathway and restricts virus infection
Authors: S Ding, J Diep, N Feng, L Ren, B Li, YS Ooi, X Wang, KF Brulois, LL Yasukawa, X Li, CJ Kuo, DA Solomon, JE Carette, HB Greenberg
Nat Commun, 2018-04-16;9(1):1485.
Species: Human
Sample Types: Cell Culture Supernates
Influenza A virus induces interleukin-27 through cyclooxygenase-2 and protein kinase A signaling.
Authors: Liu L, Cao Z, Chen J
J. Biol. Chem., 2012-02-16;287(15):11899-910.
Species: Human
Sample Types: Serum
Alpha interferon is a powerful adjuvant for a recombinant protein vaccine against foot-and-mouth disease virus in swine, and an effective stimulus of in vivo immune response.
Authors: Cheng G, Zhao X, Yan W, Wang W, Zuo X, Huang K, Liu Y, Chen J, Wang J, Cong W, Liu M, Gao H, Chen J, Lu Y, Zheng Z
Vaccine, 2007-05-24;25(28):5199-208.
Species: Porcine
Sample Types: Plasma
Elevation of IL-12 p40 and its antibody in myasthenia gravis with thymoma.
Authors: Yoshikawa H, Sato K, Edahiro S, Furukawa Y, Maruta T, Iwasa K, Watanabe H, Takaoka S, Suzuki Y, Takamori M, Yamada M
J. Neuroimmunol., 2006-03-29;175(1):169-75.
Species: Human
Sample Types: Serum