Human IFN-alpha Antibody

Catalog # Availability Size / Price Qty
21116-1
Product Details
Citations (2)
FAQs
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Human IFN-alpha Antibody Summary

Species Reactivity
Human
Specificity
Detects human interferon  alpha in direct ELISAs.
Source
Monoclonal Mouse IgG1 Clone # MMHA-13
Purification
Protein A or G purified from hybridoma culture supernatant
Immunogen
Human Leukocyte Interferon
Formulation
Phosphate-buffered saline (PBS) containing 0.1% bovine serum albumin (BSA)
Label
Unconjugated

Applications

Recommended Concentration
Sample
Direct ELISA

Binds to human interferon beta with high affinity.

 

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Shipping
The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
After receipt, the product may be stored at -20°C for short-term use ( ≤ 6 months). For long-term storage, we recommend storing the product at -70°C or below for retention of full activity. When thawing, the contents of the tube should be apportioned in separate tubes so that freezing and thawing is kept to a minimum. Refreezing should be done on dry ice or in a dry ice/alcohol bath. Further dilution of the product should be in buffers containing protein such as 0.1% bovine serum albumin (BSA).

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Long Name
Interferon alpha
Entrez Gene IDs
3440 (Human)
Alternate Names
IFNA; IFNA2; IFNA2b; IFNalpha; IFN-alpha; IFN-alphaA; INFA2; interferon alpha 2; LeIF D

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Citations for Human IFN-alpha Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

2 Citations: Showing 1 - 2
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  1. Natural killer cells can inhibit the transmission of human cytomegalovirus in cell culture by using mechanisms from innate and adaptive immune responses.
    Authors: Wu Z, Sinzger C, Reichel J, Just M, Mertens T
    J Virol, 2014-12-24;89(5):2906-17.
    Species: Human
    Sample Types: Whole Cells
    Applications: Blocking
  2. Neutralizing type I IFN antibodies trigger an IFN-like response in endothelial cells.
    Authors: Moll HP, Freudenthaler H, Zommer A
    J. Immunol., 2008-04-15;180(8):5250-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Neutralization

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