Human FFAR3/GPR41 Alexa Fluor® 594-conjugated Antibody

Catalog #: FAB10562T Datasheet / COA / SDS
Recombinant Monoclonal Antibody
Catalog # Availability Size / Price Qty
FAB10562T-100UG
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Human FFAR3/GPR41 Alexa Fluor® 594-conjugated Antibody Summary

Species Reactivity
Human
Specificity
Detects human FFAR3/GPR41 in direct ELISAs.
Source
Recombinant Monoclonal Rabbit IgG Clone # 2590G
Purification
Protein A or G purified from cell culture supernatant
Immunogen
Human FFAR3/GPR41 synthetic peptide
Formulation
Supplied 0.2 mg/mL in a saline solution containing BSA and Sodium Azide.
Label
Alexa Fluor 594 (Excitation= 590 nm, Emission= 617 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
0.25-1 µg/106 cells
U937 human histiocytic lymphoma cell line

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitution
Reconstitution default not known
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Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Protect from light. Do not freeze.
  • 12 months from date of receipt, 2 to 8 °C as supplied.

Background: FFAR3/GPR41

GPR41 and GPR42 are two closely related genes that are part of a cluster of four adjacent G protein-coupled receptors(GPR40, 41, 42, and 43). There are only six nucleotide and amino acid differences between GPR41 and GPR42. GPR41 (also known as FFAR3) is a receptor for short chain fatty acids. The rank order of potency for agonists of this receptor ispropionate = pentanoate= butyrate > acetate > formate. The activity of this receptor is coupled to the formation of inositol 1,4,5-trisphosphate, intracellular Ca2+ mobilization, the activation of ERK 1/2 and inhibition of intracellular cAMP accumulation.

Long Name
Free Fatty Acid Receptor 3
Entrez Gene IDs
2865 (Human); 233080 (Mouse); 365228 (Rat)
Alternate Names
FFA3; FFA3R; FFAR3; free fatty acid receptor 3; G protein-coupled receptor 41; GPR41; GPR41FFA3R; G-protein coupled receptor 41

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Product Specific Notices


This product is provided under an agreement between Life Technologies Corporation and R&D Systems, Inc, and the manufacture, use, sale or import of this product is subject to one or more US patents and corresponding non-US equivalents, owned by Life Technologies Corporation and its affiliates. The purchase of this product conveys to the buyer the non-transferable right to use the purchased amount of the product and components of the product only in research conducted by the buyer (whether the buyer is an academic or for-profit entity). The sale of this product is expressly conditioned on the buyer not using the product or its components (1) in manufacturing; (2) to provide a service, information, or data to an unaffiliated third party for payment; (3) for therapeutic, diagnostic or prophylactic purposes; (4) to resell, sell, or otherwise transfer this product or its components to any third party, or for any other commercial purpose. Life Technologies Corporation will not assert a claim against the buyer of the infringement of the above patents based on the manufacture, use or sale of a commercial product developed in research by the buyer in which this product or its components was employed, provided that neither this product nor any of its components was used in the manufacture of such product. For information on purchasing a license to this product for purposes other than research, contact Life Technologies Corporation, Cell Analysis Business Unit, Business Development, 29851 Willow Creek Road, Eugene, OR 97402, Tel: (541) 465-8300. Fax: (541) 335-0354.

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