Human Fc epsilon RI beta/MS4A2 (NP_000130) VersaClone cDNA

Catalog #: RDC0229 Datasheet / COA / SDS

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RDC0229

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Human Fc epsilon RI beta/MS4A2 (NP_000130) VersaClone cDNA Summary

Specifications

Source

N/A

Shipping Conditions

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Species

Human

Product Datasheets

Product Datasheet

COA

SDS

Background: Fc epsilon RI beta/MS4A2

The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. Fc epsilon RI beta/MS4A2 is the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. Fc epsilon RI beta seems to be a risk factor for atopic dermatitis and asthma.

Long Name

Fc epsilon Receptor I beta

Entrez Gene IDs

2206 (Human); 14126 (Mouse); 25316 (Rat)

Alternate Names

APY; ATOPY; Fc epsilon receptor I beta-chain; Fc epsilon RI beta; Fc epsilonRIb; FCER1B; FCER1BIGEL; FCERI; High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fcreceptor, beta-subunit) (Fc epsilon receptor I beta-chain); high affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IgE responsiveness (atopic); IGEL; IGER; IGHER; immunoglobulin E receptor, high affinity, beta polypeptide; Membrane-spanning 4-domains subfamily A member 2; membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, highaffinity I, receptor for; beta polypeptide); MS4A1; MS4A2