GW 9508

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Background References

1. Functional analysis of free fatty acid receptor GPR120 in human eosinophils: implications in metabolic homeostasis.
   Konno, Yasunori, Ueki, Shigehar, Takeda, Masahide, Kobayashi, Yoshiki, Tamaki, Mami, Moritoki, Yuki, Oyamada, Hajime, Itoga, Masamich, Kayaba, Hiroyuki, Omokawa, Ayumi, Hirokawa, Makoto
   PLoS ONE, 2015;10(3):e0120386.
2. EPA potentiates brown thermogenesis through FFAR4-dependent upregulation of miR-30b and miR-378
   
   J Biol Chem, 2016;0(0):.
3. Synthesis and activity of small molecule GPR40 agonists.
   Garrido et al.
   Bioorg.Med.Chem.Lett., 2006;16:1840
4. Pharmacological regulation of Ins secretion in MIN6 cells through fatty acid receptor GPR40: identification of agonist and antagonist small molecules.
   Briscoe et al.
   Br.J.Pharmacol., 2006;148:619
5. Activation of ATP-sensitive potassium channels in rat pancreatic β-cells by linoleic acid through both intracellular metabolites and membrane receptor signalling pathway.
   Zhao and Chen
   J.Endocrinol., 2008;198:533

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