FFN 200 dihydrochloride
Chemical Name: 4-(2-Aminoethyl)-7-amino-2H-1-benzopyran-2-one dihydrochloride
Purity: ≥98%
Biological Activity
FFN 200 dihydrochloride is a selective fluorescent VMAT2 substrate. Selectively traces exocytosis in dopaminergic neuronal cell culture and brain tissue. Excitation and emission maxima are 352 and 451 nm, respectively.Applications in Cultured Dopamine Neurons
FFN200 in vesicle clusters in axons of cultured dopaminergic neurons, and exocytosis upon high potassium stimulation (time lapse acquisition at 12 images/min).
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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Fluorescent false neurotransmitter reveals functionally silent DA vesicle clusters in the striatum.
Pereira et al.
Nat.Neurosci., 2015;19:578 -
Probes for monitoring regulated exocytosis.
Li
Cell Calcium, 2017;64:65
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Citation for FFN 200 dihydrochloride
The citations listed below are publications that use Tocris products. Selected citations for FFN 200 dihydrochloride include:
1 Citation: Showing 1 - 1
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Endogenously produced catecholamines improve the regulatory function of TLR9-activated B cells.
Authors: Matthias Et al.
PLoS Biol 2022;20:e3001513
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