EGTA

Catalog #: 2807
6 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
2807/1G

EGTA | CAS No. 67-42-5 | Buffers, Chelators and Reagents

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Description: Calcium chelating agent

Chemical Name: Ethylene glycol-bis(2-aminoethylether)-N,N,N',N'-tetraacetic acid

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Product Details

Citations (6)

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Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

EGTA is a calcium chelator; protects against cell death caused by nitric oxide-induced calcium influx into nerve cells.

Technical Data

M.Wt:

380.35

Formula:

C₁₄H₂₄N₂O₁₀

Solubility:

Soluble to 100 mM in 1M NaOH

Storage:

Store at RT

CAS No:

67-42-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Role of calcium in nitric oxide-induced cytotoxicity: EGTA protects mouse oligodendrocytes.
Boullerne et al.
J.Neurosci.Res., 2001;63:124
Catalytic superoxide scavenging by metal complexes of the calcium chelator EGTA and contrast agent EHPG.
Fisher et al.
Biochem.Biophy.Res.Comms., 2004;323:163

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Citations for EGTA

The citations listed below are publications that use Tocris products. Selected citations for EGTA include:

6 Citations: Showing 1 - 6

Neuroprotection and spatial memory enhancement of four herbal mixture extract in HT22 hippocampal cells and a mouse model of focal cerebral ischemia.
Authors: Ahn Et al.
Carcinogenesis 2015;15:202
TMEM203 Is a Novel Regulator of Intracellular Calcium Homeostasis and Is Required for Spermatogenesis.
Authors: Shambharkar Et al.
BMC Complement Altern Med 2015;10:e0127480
Areca nut-induced buccal mucosa fibroblast contraction and its signaling: a potential role in oral submucous fibrosis--a precancer condition.
Authors: Chang Et al.
PLoS One 2013;34:1096
On the mechanism of synaptic depression induced by CaMKIIN, an endogenous inhibitor of CaMKII.
Authors: Gouet Et al.
PLoS One 2012;7:e49293
Genistein and tyrphostin AG556 inhibit inwardly-rectifying Kir2.1 channels expressed in HEK 293 cells via protein tyrosine kinase inhibition.
Authors: Zhang Et al.
Biochim Biophys Acta 2011;1808:1993
Endocannabinoid signaling mediates psychomotor activation by adenosine A2A antagonists.
Authors: Lerner Et al.
J Neurosci 2010;30:2160

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