Dynole 34-2

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Endophilin marks and controls a clathrin-independent endocytic pathway.
   Boucrot E, Ferreira A, Almeida-Souza L, Debard S, Vallis Y, Howard G, Bertot L, Sauvonnet N, McMahon H
   Nature, 2015;517(7535):460-5.
2. Multiplex assay for live-cell monitoring of cellular fates of amyloid-beta precursor protein (APP).
   Merezhko M, Muggalla P, Nykanen N, Yan X, Sakha P, Huttunen H
   PLoS ONE, 2014;9(6):e98619.
3. Combining valosin-containing protein (VCP) inhibition and suberanilohydroxamic acid (SAHA) treatment additively enhances the folding, trafficking, and function of epilepsy-associated gamma-aminobutyric acid, type A (GABAA) receptors.
   Han D, Di X, Fu Y, Mu T
   J Biol Chem, 2015;290(1):325-37.
4. Inhibition of dynamin mediated endocytosis by the dynoles - synthesis and functional activity of a family of indoles.
   Hill et al.
   J.Med.Chem., 2009;52:3762
5. Iminochromene inhibitors of dynamins I and II GTPase activity and endocytosis.
   Hill et al.
   J.Med.Chem., 2010;53:4094

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