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dCeMM2

Catalog #: 7525 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7525/10
7525/50
dCeMM2 | CAS No. 296771-07-8 | Molecular Glues
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Description: Molecular glue Degrader; induces ubiquitination and degradation of cyclin K

Chemical Name: N-(5-Chloro-2-pyridinyl)-2-(5H-1,2,4-triazino[5,6-b]indol-3-ylthio)acetamide

Purity: ≥98%

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Biological Activity

dCeMM2 is a molecular glue degrader. Induces ubiquitination and degradation of cyclin K by eliciting an interaction of CDK12-cyclin K with a CRL4B ligase complex. dCeMM2 displays near-total degradation of protein at 2.5 μM within 2h. Cell-permeable.

Technical Data

M.Wt:
370.82
Formula:
C16H11ClN6OS
Solubility:
Soluble to 50 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
296771-07-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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