Daunorubicin hydrochloride

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Doxorubicin induces cardiotoxicity through upregulation of death receptors mediated apoptosis in cardiomyocytes
   L Zhao, B Zhang
   Sci Rep, 2017;7(0):44735.
2. Daunorubicin and doxorubicin, anthracycline antibiotics, a physicochemical and biological review.
   Aubel-Sadron and Londos-Gagliardi
   Biochimie, 1984;66:333
3. Pharmacologic reductions of total tau levels; implications for the role of microtubule dynamics in regulating tau expression.
   Dickey et al.
   Mol.Neurodegen., 2006;1:6
4. A critical evaluation of the mechanisms of action proposed for the antitumor effects of the anthracycline antibiotics adriamycin and daunoru.
   Gewirtz
   Biochem.Pharmacol., 1999;57:727
5. Signaling pathways activated by daunoru.
   Laurent and Jaffrezou
   Blood, 2001;98:913
6. Identification and validation of small molecules that enhance recombinant adeno-associated virus transduction following high-throughput screens.
   Nicolson et al.
   J.Virol., 2016;90:7019
7. DNA topoisomerases and their poisoning by anticancer and antibacterial drugs.
   Pommier et al.
   Chem.Biol., 2010;17:421
8. A SARS-CoV-2-human protein-protein interaction map reveals drug targets and potential drug-repurposing.
   Gordon et al.
   Nature, 2020;

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