Cirazoline hydrochloride

Biological Activity

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. Hindbrain oxytocin receptors contribute to the effects of circulating oxytocin on food intake in male rats.
   Ho J, Anekonda V, Thompson B, Zhu M, Curry R, Hwang B, Morton G, Schwartz M, Baskin D, Appleyard S, Blevins J
   Endocrinology, 2014;155(8):2845-57.
2. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
   Fox JT, Sakamuru S, Huang R
   Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
3. Renal effects of selective alpha-1 and alpha-2 adrenoreceptor agonists in conscious normotensive rats.
   Gellai and Ruffolo
   J.Pharmacol.Exp.Ther., 1987;240:723
4. Binding of [³H]cirazoline to an imidazoline site in rat brain and kidney membranes.
   Le Rouzic et al.
   Eur.J.Pharmacol., 1995;278:261
5. Further characterisation of the guinea pig cerebral cortex idazoxan receptor: solubilization, distinction from the imidazole site, and demonstration of cirazoline as an idazoxan receptor-selective drug.
   Wikberg and Uklen
   J.Neurochem., 1990;55:192

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