Cardamonin

Catalog # Availability Size / Price Qty
2509/10
2509/50
Cardamonin | CAS No. 19309-14-9 | NFkB/IkB Inhibitors
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Description: Inhibitor of NF-κB activation; anti-inflammatory

Chemical Name: (2E)-1-(2,4-Dihydroxy-6-methoxyphenyl)-3-phenyl-2-propen-1-one

Purity: ≥98%

Product Details
Citations (3)
Reviews

Biological Activity

Cardamonin is a chalone analog that display anti-inflammatory activity. Inhibits NO and PGE2 production from LPS- and IFN-γ-induced RAW cells and inhibits TXB2 production via the COX-1 and COX-2 pathways. Inhibits NF-κB activation via inhibition of IκBα degradation and phosphorylation, IκB kinase activation and NF-κB nuclear translocation.

Technical Data

M.Wt:
270.28
Formula:
C16H14O4
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
19309-14-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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Citations for Cardamonin

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3 Citations: Showing 1 - 3

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