Camostat mesylate

Biological Activity

Tocris products are for biomedical research use only. They are not intended for human or veterinary use.

Technical Data

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

1. TMPRSS2 activates the human coronavirus 229E for cathepsin-independent host cell entry and is expressed in viral target cells in the respiratory epithelium.
   Bertram S, Dijkman R, Habjan M, Heurich A, Gierer S, Glowacka I, Welsch K, Winkler M, Schneider H, Hofmann-Winkler H, Thiel V, Pohlmann S
   J Virol, 2013;87(11):6150-60.
2. Gabexate and camostat, synthetic proteinase inhibitors, as direct inducing factors of water and bicarbonate secretion in the isolated and blood-perfused dog pancreas.
   Horiuchi et al.
   J.Pharmacol.Exp.Ther., 1990;252:320
3. The proteinase inhibitor camostat mesilate suppresses pancreatic pain in rodents.
   Ishikura et al.
   Life Sci., 2007;80:1999
4. SARS-CoV-2 cell entry depends on ACE2 and TMPRSS2 and is blocked by a clinically-proven protease inhibitor.
   Hoffmann et al.
   Cell, 2020;

Product Datasheets