Home / Src Family Kinase Ligands / Caffeic acid-pYEEIE

Caffeic acid-pYEEIE

Catalog #: 1935
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1935/1
Caffeic acid-pYEEIE
1 Image
Description: Phosphopeptide ligand for src SH2 domain

Chemical Name: N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-O-phosphono-L-tyrosyl-L-α-glutamyl-L-α-glutamyl-L-isoleucyl-L-glutamic acid

Purity: ≥95%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Caffeic acid-pYEEIE is a phosphopeptide ligand for the src SH2 domain (IC50 = 42 nM); displays 30-fold higher affinity than N-acetyl-O-phosphono-Tyr-Glu-Glu-Ile-Glu (Ac-pYEEIE, Cat. No. 1927).

Technical Data

M.Wt:
923.82
Formula:
C39H50N5O19P
Sequence:
YEEIE

(Modifications: Tyr-1 = N-[3-(3,4-Dihydroxyphenyl)-1-oxo-2-propenyl]-)-pTyr)

Solubility:
Soluble to 2 mg/ml in PBS
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
507471-72-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Design and characterization of non-phosphopeptide inhibitors for src family SH2 domains.
    Park et al.
    Bioorg.Med.Chem.Lett., 2002;12:2711

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citation for Caffeic acid-pYEEIE

The citations listed below are publications that use Tocris products. Selected citations for Caffeic acid-pYEEIE include:

1 Citation: Showing 1 - 1

  1. A selective NMR probe to monitor the conformational transition from inactive to active kinase.
    Authors: Xie Et al.
    J Neurosci  2015;10:262

FAQs

No product specific FAQs exist for this product, however you may

View all Peptide FAQs

Reviews for Caffeic acid-pYEEIE

There are currently no reviews for this product. Be the first to review Caffeic acid-pYEEIE and earn rewards!

Have you used Caffeic acid-pYEEIE?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.