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BSJ-Bump

Catalog #: 6922 Datasheet / COA / SDS

Discontinued Product

6922 has been discontinued.
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BSJ-Bump | CAS No. 2409918-48-3 | Active Degrader Negative Controls
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Description: Negative control for BSJ-03-123 (Cat. No. 6921)

Chemical Name: N-(2-(2-(2-(2-(4-(6-((6-Acetyl-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazin-1-yl)ethoxy)ethoxy)ethoxy)ethyl)-2-((2-(1-methyl-2,6-dioxopiperidin-3-yl)-1,3-dioxoisoindolin-4-yl)oxy)acetamide

Purity: ≥98%

Product Details
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Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

BSJ-Bump is a negative control for BSJ-03-123 (Cat. No. 6921). Displays binding and no degradation of Cdk6 in vitro.

Technical Data

M.Wt:
951.05
Formula:
C48H58N10O11
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2409918-48-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license from Dana-Farber Cancer Institute

Background References

  1. Homolog-selective degradation as a strategy to probe the function of CDK6 in AML.
    Brand et al.
    Cell Chem.Biol., 2019;26:300

Product Datasheets

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