Autocamtide-2-related inhibitory peptide, myristoylated
Purity: ≥95%
Biological Activity
Autocamtide-2-related inhibitory peptide, myristoylated is a CaM kinase II inhibitor; enhanced cell permeable derivative of Autocamtide-2-related inhibitory peptide (Cat No. 1688). Pretreatment blocks reinstatement of morphine-seeking behavior in vivo.Technical Data
(Modifications: Lys-1 = Myr-Lys)
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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Neuroprotective effect of AIP on N-methyl-D-aspartate-induced cell death in retinal neurons.
Laabich et al.
Brain Res.Mol.Brain Res., 2000;85:32 -
Inhibition of CaMKII activity in the nucleus accumbens shell blocks the reinstatement of morphine-seeking behavior in rats.
Liu et al.
Neurosci.Lett., 2012;518:167 -
A novel highly specific and potent inhibitor of calmodulin-dependent protein kinase II.
Ishida et al.
Biochem.Biophys.Res.Commun., 1995;212:806
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