Home / Integrin Receptor Inhibitors / A 286982

A 286982

Catalog #: 4228
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
4228/10
4228/50
A 286982 | CAS No. 280749-17-9 | Integrin Receptor Inhibitors
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Description: Potent inhibitor of the LFA-1/ICAM-1 interaction

Chemical Name: (2E)-1-(4-Acetyl-1-piperazinyl)-3-[4-[[2-(1-methylethyl)phenyl]thio]-3-nitrophenyl]-2-propen-1-one

Purity: ≥99%

Product Details
Citations (1)
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Biological Activity

A 286982 is a potent inhibitor of the LFA-1/ICAM-1 interaction (IC50 values are 44 and 35 nM in LFA-1/ICAM-1 binding and LFA-1-mediated cell adhesion assays respectively).

Technical Data

M.Wt:
453.55
Formula:
C24H27N3O4S
Solubility:
Soluble to 100 mM in DMSO and to 50 mM in ethanol
Purity:
≥99%
Storage:
Store at RT
CAS No:
280749-17-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for A 286982

The citations listed below are publications that use Tocris products. Selected citations for A 286982 include:

1 Citation: Showing 1 - 1

  1. Approaches for investigating the extracellular signaling function of ISG15.
    Authors: Jon M Et al.
    Methods Enzymol  2019;618:211-227

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