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CTLA-4: Products
CTLA-4/CD152 (Cytotoxic T-Lymphocyte Antigen 4) is a transmembrane T cell inhibitory molecule that is expressed as a covalent homodimer. CTLA-4 is recruited from intracellular vesicles to the immunological synapse beginning 1-2 days after T cell activation. It forms a linear lattice with B7-1 on APC, inducing negative regulatory signals and ending CD28-dependent T cell activation. Mice deleted for CTLA-4 develop lethal autoimmune reactions due to continued T cell activation and poor control by regulatory T cells which constitutively express CTLA-4.
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"CTLA-4" has 74 results in Products.
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Non-Human Primate CTLA-4 Cartridge
Simple Plex Non-Human Primate CTLA-4 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Custom Simple Plex™ Assay Panels
Build your own multi-plex biomarker immunoassay panel for Ella™. Highly precise and reproducible. Choose from more than 250 fully validated target analytes.
Proteome Profiler Human Phospho-Immunoreceptor Array Kit
Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies
