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HVEM/TNFRSF14: Products
HVEM/TNFRSF14 (herpesvirus entry mediator) is a transmembrane protein that is most highly expressed on naïve, memory, and regulatory T cells but declines during T cell activation. It is present at low levels on most resting leukocytes. HVEM is a receptor for BTLA, CD160, and LIGHT.
A cis interaction between HVEM and BTLA promotes cell survival, while trans interaction promotes a state of lymphocyte inactivity. LIGHT is expressed following T cell activation and competes with BTLA for HVEM binding, leading to a proinflammatory response. The herpesvirus envelope glycoprotein gD, which binds HVEM to initiate membrane fusion, can antagonize both BTLA and LIGHT binding. Human, but not mouse, HVEM can also bind lymphotoxin-alpha.
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"HVEM/TNFRSF14" has 48 results in Products.
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Simple Plex Control for Human HVEM/TNFRSF14
Control for use with Human HVEM/TNFRSF14 Simple Plex Cartridge Kit
Simple Plex Human HVEM/TNFRSF14 Cartridge
Simple Plex Human HVEM/TNFRSF14 assay kit for use on Ella instrument. Contains cartridge, sample diluent SD13, and wash buffer.
Custom Simple Plex™ Assay Panels
Build your own multi-plex biomarker immunoassay panel for Ella™. Highly precise and reproducible. Choose from more than 250 fully validated target analytes.
Proteome Profiler Human NFkB Pathway Array
Contains 4 membranes-each spotted in duplicate with 41 different proteins and 4 serine or tyrosine phosphorylation sites antibodies
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