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CEACAM-1/CD66a: Products
CEACAM-1, also known as CD66a, is an immunoglobulin superfamily protein that is expressed on neutrophils, activated NK cells, bile duct and colonic epithelial cells, and endothelial cells. CEACAM-1 is heavily glycosylated and carries high mannose residues and (sialyl) Lewis-x. It is expressed as at least three soluble and seven transmembrane isoforms, with variations occurring in both the ECD and cytoplasmic regions. It engages in homotypic adhesion and heterotypic adhesion with CEACAM-3/CD66d and CEACAM-6/CD66c. On neutrophils, CEACAM-1 additionally binds to dendritic cell DC-SIGN via its Lewis-x moiety, inducing dendritic cell maturation and a subsequent Th1-type response.
Products:
- Primary Antibodies
- Proteins & Enzymes
- cDNA Clones
- Proteome Profiler Antibody Arrays
- ELISAs
- Luminex Assays
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"CEACAM-1/CD66a" has 35 results in Products.
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Proteome Profiler Human sReceptor Array, Non-hematopoietic
Contains 4 membranes - 2 spotted in duplicate with 62 different non-hematopoietic antibodies and 2 spotted in duplicate with 57 common antibodies
Proteome Profiler Human Phospho-Immunoreceptor Array Kit
Contains 4 membranes - each spotted in duplicate with 59 different immunoreceptor antibodies
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