Mesenchymal Stem Cell Markers

Click on one of the stem cell types shown in the buttons below to see the markers that are commonly used to identify each cell type.

Embryonic or Induced Pluripotent Hematopoietic Mesenchymal Neural

Cell Surface Markers

5' Nucleotidase/CD73

ALCAM/CD166

BMP Receptors

CD11b/Integrin alpha M^-

CD14^-

CD19^-

CD34^-

CD44

CD45^-

CD79A^-

CD90/Thy1

CD105/Endoglin

CD117/c-kit

Integrin alpha 1/CD49a

Integrin alpha V/CD51

Integrin beta 1/CD29

Sca-1⁺, Lin^- (mouse)

STRO-1

VCAM-1/CD106

Intracellular Markers

Nucleostemin

Overview

Mesenchymal stem cells (MSCs) are progenitor cells found in the bone marrow and other tissues. These multipotent, self-renewing cells give rise to osteoblasts, chondrocytes, myocytes, and adipocytes. Levels of these progenitor cells play a role in regenerative medicine, immune system modulation, and other cell therapies.

Data Examples

Detection of Cell Surface Markers on Human Bone Marrow-derived Mesenchymal Stem Cells
View Larger

Detection of Cell Surface Markers on Human Bone Marrow-derived Mesenchymal Stem Cells by Flow Cytometry. Human bone marrow-derived mesenchymal stem cells were stained using reagents supplied in the Human Mesenchymal Stem Cell Verification Multi-Color Flow Cytometry Kit (R&D Systems, Catalog # FMC020). The data shows positive expression of the mesenchymal stem cell-associated surface antigens, 5'Nucleotidase/CD73, CD105/Endoglin, and CD90/Thy1, as well as negative expression of all markers included in the negative marker cocktail including CD11b/Integrin alpha M, CD34, CD45, CD79A, and HLA-DR. Quadrants were set based on staining with the appropriate negative controls.