YS-035 hydrochloride
Chemical Name: N,N-Bis-(3,4-dimethoxyphenylethyl)-N-methylamine hydrochloride
Biological Activity
YS-035 hydrochloride is a Ca2+ blocker that strikingly prolongs cardiac action potentials by inhibiting pacemaker current and K+ outward currents.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
Fox JT, Sakamuru S, Huang R
Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8. -
Properties of a new calcium ion antagonist on cellular uptake and mitochondrial efflux of calcium ions.
Deana et al.
Biochem.J., 1984;218:899 -
Inhibition of potassium outward currents and pacemaker current in sheep cardiac Purkinje fibres by the vera. derivative YS-035.
Berger et al.
Naunyn Schmiedebergs Arch.Pharmacol., 1991;344:653
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