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VH 101, thiol

Catalog #: 7884 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7884/50
VH 101, thiol | CAS No. 2358775-81-0 | Degrader Building Blocks
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Description: Thiol functionalized VHL ligand

Chemical Name: (2S,4R)-1-[(2R)-2-[[(1-Fluorocyclopropyl)carbonyl]amino]-3-methyl-3-sulfanyl-butanoyl]-4-hydroxy-N-[[4-(4-methylthiazol-5-yl)phenyl]methyl]pyrrolidine-2-carboxamide

Purity: ≥95%

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Biological Activity

VH 101, thiol is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand with terminal thiol ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
534.67
Formula:
C25H31FN4O4S2
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2358775-81-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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