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VH 032 amide-alkylC7-amine

Catalog #: 7074
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7074/25
VH 032 amide-alkylC7-amine | Degrader Building Blocks
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Description: VHL ligand with alkyl linker and terminal amine for onward chemistry
Alternative Names: (S,R,S)-AHPC-C7-NH2

Chemical Name: (2S,4R)-1-((S)-2-(8-Aminooctanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide hydrochloride

Purity: ≥95%

Product Details
Citations (1)
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Biological Activity Technical Data Product Datasheets Calculators

Biological Activity

VH 032 amide-alkylC7-amine is a functionalized von-Hippel-Lindau protein ligand (VHL) for PROTAC® research and development; incorporates an E3 ligase ligand plus an alkyl linker ready for conjugation to a target protein ligand. Part of a range of functionalized tool molecules for PROTAC R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used. This product is sold as an xHCl salt. The stoichiometry of the salt and hydration levels vary from batch to batch. It is sold in gross weight with the batch specific Molecular Weight available on the Certificate of Analysis

Technical Data

M. Wt
571.78 (Free Base)
Formula:
C30H45N5O4S.xHCl
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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Citation for VH 032 amide-alkylC7-amine

The citations listed below are publications that use Tocris products. Selected citations for VH 032 amide-alkylC7-amine include:

1 Citation: Showing 1 - 1

  1. Fibroblasts Mobilize Tumor Cell Glycogen to Promote Proliferation and Metastasis.
    Authors: Jason W Et al.
    Cell Metab  2019;29:141-155.e9

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