UCLA GP130 2
Chemical Name: N-(4-Fluorophenyl)-4-phenyl-2-thiazolamine
Purity: ≥98%
Biological Activity
UCLA GP130 2 is a gp130 agonist. Protects against NMDA-induced toxicity in primary hippocampal neurons in vitro. Increases STAT3 phosphorylation in SH-SY5Y cells. Brain penetrant.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
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A small molecule mimetic of the humanin peptide as a candidate for modulating NMDA-induced neurotoxicity.
Alam et al.
ACS Chem.Neurosci., 2018;9:462
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