Tocriscreen FDA-Approved Drugs Library
Biological Activity
Tocriscreen FDA-Approved Drugs Library is a library of 190 compounds equivalent to the pharmacologically active components of drug formulations approved by the FDA. Compounds supplied pre-dissolved in DMSO (100 μL, 10 mM solution). Contains compounds covering a diverse range of pharmaceutical targets and therapeutic areas e.g. immunology, oncology. Includes both established therapeutics, e.g. tamoxifen (Cat. No. 0999) and paclitaxel (Cat. No. 1097), as well as more recently approved drugs such as darunavir (Cat. No. 6710) and sorafenib (Cat. No. 6814). Ideal for in vitro and in vivo drug repurposing/repositioning studies.This library replaces the Tocriscreen Library of FDA-Approved Compounds (Cat. No. 5932).
All Tocris products are for biomedical research use only. They are not intended for human or veterinary use.
Key Format and Product Details
- All compounds are equivalent to active components of FDA-approved drug formulations
- Full chemical and biological data available in Excell and SD file formats
- 96-well racks with Matrix storage tubes & SepraSeal caps
- Compounds arranged with a maximum of 80 per rack with 3 racks per library
- Pre-dissolved in 100 μL 10 mM DMSO solutions
- Compounds produced to same high chemical standard as Tocris catalog
The Tocriscreen FDA-approved Drugs Library contains bioactive compounds covering a diverse range of therapeutic classifications, derived using the WHO Anatomical Therapeutic Chemical Classification System code (ATC code).
Request Compound List
A list of the compounds available in the Tocriscreen FDA-Approved Drugs Library can be requested in Excel or SD format via our Tocriscreen & Custom Library Inquiries form.
Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
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The University of New Mexico Center for Molecular Discovery.
Edwards et al.
Comb.Chem.High Throughput Screen., 2014;17:256 -
Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons.
Li et al.
Cell Stem Cell, 2015;17:195
Product Datasheets
Reconstitution Calculator
Citations for Tocriscreen FDA-Approved Drugs Library
The citations listed below are publications that use Tocris products. Selected citations for Tocriscreen FDA-Approved Drugs Library include:
7 Citations: Showing 1 - 7
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Drug repurposing screen identifies novel anti-inflammatory activity of sunitinib in macrophages.
Authors: Chaffey Et al.
Eur.J.Pharmacol. 2024;969:176437
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Nebivolol sensitizes BT-474 breast cancer cells to FGFR inhibitors.
Authors: Kim Et al.
Anticancer Res. 2023;43:1973
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Zebrafish Larvae Position Tracker (Z-LaP Tracker): a high-throughput deep-learning behavioral approach for the identification of calcineurin pathway-modulating drugs using zebrafish larvae.
Authors: Gore Et al.
Sci.Rep. 2023;13:3174
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Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery.
Authors: Gull Et al.
Cold Spring Harb.Protoc. 2023;
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Novel use of FDA-approved drugs identified by cluster analysis of behavioral profiles.
Authors: Edmister Et al.
Sci.Rep. 2022;12:6120
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Using in silico modelling and FRET-based assays in the discovery of novel FDA-approved drugs as inhibitors of MERS-CoV helicase.
Authors: Mehyar Et al.
SAR QSAR Environ Res 2020;6:1
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Saracatinib Inhibits Middle East Respiratory Syndrome-Coronavirus Replication In Vitro.
Authors: Shin Et al.
Viruses 2018;10:E283
FAQs
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