TGF-beta 3 Biotinylated Antibody

Catalog #: BAM243
1 Citation Datasheet / COA / SDS

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BAM243

All TGF-beta 3 Antibodies

Product Details

Citations (1)

Supplemental Products

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

TGF-beta 3 Biotinylated Antibody Summary

Specificity

Detects human TGF-beta 3 in Western blots and direct ELISAs. In Western blots and direct ELISAs, approximately 20% cross‑reactivity with TGF-beta 1.2 and TGF-beta 2 is observed, 5% cross-reactivity with TGF-beta 1 is observed and no cross-reactivity with recombinant human (rh) ART, recombinant mouse Artemin, recombinant drosophilia DPP, rhGDNF, rhLAP, rhLAT TGF-beta 1, rhLEFTY, recombinant rat MIS, rhNeurturin, recombinant amphibian TGF-beta 5, or rhTGF-alpha is observed.

Source

Monoclonal Mouse IgG₁ Clone # 20724

Purification

Protein A or G purified from ascites

Immunogen

recombinant human (rh) TGF-beta 3 Ala301-Ser412 (Tyr340Phe), accession # P10600, mixed with rhTGF-beta 1, rhTGF-beta 2, recombinant canine TGF‑ beta 3, and recombinant amphibian TGF-beta 5

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.

Label

Biotin

Applications

Recommended Concentration

Sample

Western Blot

1 µg/mL

Recombinant Human TGF-beta 3 (Catalog # 243-B3) under non-reducing conditions only

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS.

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: TGF-beta 3

TGF-beta 1, -2 and -3 are a closely related group of proteins (70‑80% sequence homology) that are produced by many cell types and function as growth and differentiation factors. The active forms of TGF-beta 1, -2 and -3 are disulfide-linked homodimers.

Long Name

Transforming Growth Factor beta 3

Entrez Gene IDs

7043 (Human); 21809 (Mouse); 25717 (Rat)

Alternate Names

ARVD; ARVD1; FLJ16571; LDS5; RNHF; TGFB3; TGFbeta 3; TGF-beta 3; TGF-beta3; TGF-beta-3; transforming growth factor beta-3; transforming growth factor, beta 3

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citation for TGF-beta 3 Biotinylated Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

Systemic and local characterization of regulatory T cells in a chronic fungal infection in humans.
Authors: Cavassani KA, Campanelli AP, Moreira AP, Vancim JO, Vitali LH, Mamede RC, Martinez R, Silva JS
J. Immunol., 2006-11-01;177(9):5811-8.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry