TC-FPR 43

Catalog # Availability Size / Price Qty
4624/50
4624/10
TC-FPR 43 | CAS No. 903895-98-7 | FPRL1/FPR2
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Description: Potent FPR2 agonist

Chemical Name: N-(4-Chlorophenyl)-N-[2,3-dihydro-1-methyl-5-(1-methylethyl)-3-oxo-2-phenyl-1H-pyrazol-4-yl]-urea

Purity: ≥98%

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Biological Activity

TC-FPR 43 is a potent formyl peptide receptor 2 (FPR2) agonist (EC50 = 44 nM). Inhibits fMLP- and IL-8-induced neutrophil migration. Suppresses inflammation in a mouse model of acute inflammation. Orally bioavailable.

Technical Data

M.Wt:
384.86
Formula:
C20H21ClN4O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
903895-98-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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