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STX 64

Catalog #: 7341 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
7341/25
7341/5
STX 64 | CAS No. 288628-05-7 | Hydrolase Inhibitors
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Description: Potent steroid sulfatase inhibitor; also inhibits carbonic anhydrase II

Chemical Name: 6,7,8,9,10,11-Hexahydro-6-oxobenzo[b]cyclohepta[d]pyran-3-yl sulfamate

Purity: ≥98%

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Biological Activity

STX 64 is a potent steroid sulfatase inhibitor (IC50 = 8 nM). Estrone sulfate-stimulated uterine growth and mammary tumor growth are inhibited by STX 64 in animal models. STX 64 shows inhibition of steroid sulfatase activity in peripheral blood lymphocytes, liver and tumor tissues and is active in vivo. STX 64 is also a potent inhibitor of carbonic anhydrase II (IC50 = 25 nM).

Technical Data

M.Wt:
309.34
Formula:
C14H15NO5S
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
288628-05-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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