SR 1078
Chemical Name: N-[4-[2,2,2-Trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-4-(trifluoromethyl)benzamide
Purity: ≥98%
Biological Activity
SR 1078 is an agonist of retinoic acid receptor-related orphan receptors (ROR) RORα/γ. Increases transcription of RORα target genes; thought to increase p53 stability.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Additional Information
Background References
-
Regulation of p53 stability and apoptosis by a ROR agonist.
Wang et al.
PLoS One, 2012;7:e34921 -
Identification of a synthetic agonist for the orphan nuclear receptors RORα and RORγ, SR1078.
Wang et al.
ACS Chem.Biol., 2010;5:1029
Product Datasheets
Reconstitution Calculator
Molarity Calculator
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for SR 1078
There are currently no reviews for this product. Be the first to review SR 1078 and earn rewards!
Have you used SR 1078?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
