Home / delta Opioid Receptor Agonists / SB 205607 dihydrobromide

SB 205607 dihydrobromide

Catalog #: 0921
2 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
0921/10
SB 205607 dihydrobromide | CAS No. 1217628-73-3 | delta Opioid Receptor Agonists
1 Image
Description: Selective, high affinity non-peptide δ1 agonist
Alternative Names: TAN 67

Chemical Name: (R*,S*)-(±)-2-Methyl-4aa-(3-hydroxyphenyl)-1,2,3,4,4a,5,12,12aa-octahydroquinolino[2,3,3-g]isoquinoline dihydrobromide

Purity: ≥97%

Product Details
Citations (2)
Supplemental Products
Reviews
Biological Activity Technical Data Additional Information Background Product Datasheets Calculators

Biological Activity

The first described non-peptide δ1 opioid receptor agonist with very high affinity and selectivity for the δ1 subtype (Ki values are 1.12, 2320 and 1790 nM at δ1, μ and κ receptors respectively).

Technical Data

M.Wt:
506.28
Formula:
C23H24N2O.2HBr
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
≥97%
Storage:
Store at RT
CAS No:
1217628-73-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
Sold under license

Background References

  1. Antinociceptive effects of the selective non-peptidic δ-opioid receptor agonist TAN-67 in diabetic mice.
    Kamei et al.
    Eur.J.Pharmacol., 1995;276:131
  2. The pharmacological profile of δ opioid receptor ligands (+) and (-) TAN-67 on pain modulation.
    Nagase et al.
    Life Sci., 2001;68:2227
  3. Properties of TAN-67, a non-peptidic β-opioid receptor agonist, at cloned human δ- and μ-opioid receptors.
    Knap et al.
    Eur.J.Pharmacol., 1995;291:129
  4. Syntheses of non-peptidic delta opioid agonists and their structure-activity relationships.
    Nagase et al.
    Jpn.J.Pharmacol., 1994;64:Suppl. 1, 35P

Product Datasheets

COA view current batch
Or select another batch:
View Batch
SDS
Reconstitution Calculator
Molarity Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Molarity Calculator

=
x
x
g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for SB 205607 dihydrobromide

The citations listed below are publications that use Tocris products. Selected citations for SB 205607 dihydrobromide include:

2 Citations: Showing 1 - 2

  1. Critical Role for Gi/o-Protein Activity in the Dorsal Striatum in the Reduction of Voluntary Alcohol Intake in C57Bl/6 Mice.
    Authors: Robins Et al.
    Front Psychiatry  2018;9:112
  2. The delta opioid receptor antagonist, SoRI-9409, decreases yohimbine stress-induced reinstatement of ethanol-seeking.
    Authors: Nielsen Et al.
    Addict Biol  2012;17:224

FAQs

No product specific FAQs exist for this product, however you may

View all Small Molecule FAQs
Loading...

Reviews for SB 205607 dihydrobromide

There are currently no reviews for this product. Be the first to review SB 205607 dihydrobromide and earn rewards!

Have you used SB 205607 dihydrobromide?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review
Tocris Bioscience is the leading supplier of novel and exclusive tools for life science research with over 30 years' experience in the industry. Tocris is a Bio-Techne brand.