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(RS)-AMPA hydrobromide

Catalog #: 1074
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
1074/10
1074/50
1074/1
(RS)-AMPA hydrobromide | CAS No. 171259-81-7 | AMPA Receptor Agonists
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Description: Selective AMPA agonist; more water soluble form of (RS)-AMPA (Cat. No. 0169)

Chemical Name: (RS)-α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid hydrobromide

Purity: ≥99%

Product Details
Citations (5)
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Biological Activity

(RS)-AMPA hydrobromide is a more water soluble hydrobromide salt of (RS)-AMPA (Cat. No. 0169).

Technical Data

M.Wt:
267.08
Formula:
C7H10N2O4.HBr
Solubility:
Soluble to 10 mM in water with gentle warming
Purity:
≥99%
Storage:
Desiccate at +4°C
CAS No:
171259-81-7

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. High-throughput genotoxicity assay identifies antioxidants as inducers of DNA damage response and cell death.
    Fox JT, Sakamuru S, Huang R
    Proc. Natl. Acad. Sci. U.S.A., 2012;109(14):5423-8.
  2. The binding of 3H-AMPA, a structural analogue of glutamic acid, to rat brain membranes.
    Honore et al.
    J.Neurochem., 1982;38:173
  3. New class of glutamate agonist structurally related to ibotenic acid.
    Krogsgaard-Larsen et al.
    Nature, 1980;284:64

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Citations for (RS)-AMPA hydrobromide

The citations listed below are publications that use Tocris products. Selected citations for (RS)-AMPA hydrobromide include:

5 Citations: Showing 1 - 5

  1. Sex-regulated gene dosage effect of PPARα on synaptic plasticity.
    Authors: Pierrot Et al.
    Life Sci Alliance  2019;2
  2. Activity-dependent trafficking of lysosomes in dendrites and dendritic spines.
    Authors: Goo Et al.
    J Cell Biol  2017;216:2499
  3. Impact of subanesthetic doses of KA on AMPA-mediated responses in rats: An in vivo electrophysiological study on monoaminergic and glutamatergic neurons.
    Authors: Iskandrani Et al.
    J Neurosci  2015;29:792
  4. Neurons generated by direct conversion of fibroblasts reproduce synaptic phenotype caused by autism-associated neuroligin-3 mutation.
    Authors: Chanda Et al.
    J Psychopharmacol  2013;110:16622
  5. AMPA receptor activation causes silencing of AMPA receptor-mediated synaptic transmission in the developing hippocampus.
    Authors: Wasling Et al.
    PLoS One  2012;7:e34474

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