Home / IL-3 / Recombinant Mouse IL-3 Protein

Recombinant Mouse IL-3 Protein

Catalog #: 403-ML
178 Citations 6 Reviews Datasheet / COA / SDS
Analyzed by SEC-MALS

Carrier Free

Catalog # Availability Size / Price Qty
403-ML-010/CF
403-ML-050/CF
403-ML-500/CF
403-ML-025/CF
403-ML-100/CF
403-ML-01M/CF

With Carrier

Catalog # Availability Size / Price Qty
403-ML-010
403-ML-050
403-ML-500
403-ML-100
403-ML-025
Best Seller
Recombinant Mouse IL‑3 Protein SEC-MALS.
3 Images
Product Details
Citations (178)
FAQs
Reviews (6)
Summary Product Datasheets Carrier Free Data Images Reconstitution Calculator Background Related Research Areas

Recombinant Mouse IL-3 Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using NFS‑60 mouse myelogenous leukemia lymphoblast cells. Holmes, K.L. et al. (1985) Proc. Natl. Acad. Sci. USA 82:6687. The ED50 for this effect is 20-100 pg/mL.
Source
E. coli-derived mouse IL-3 protein
Asp33-Cys166, with an N-terminal Met
Accession #
NP_034686
N-terminal Sequence
Analysis
Asp33
Predicted Molecular Mass
15 kDa

Product Datasheets

You must select a language.

x

403-ML (with carrier)

Product Datasheet
COA
SDS

You must select a language.

x

403-ML/CF (carrier free)

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

403-ML

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

403-ML/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Scientific Data

SEC-MALS View Larger

Recombinant Mouse IL-3 Protein (Catalog # 403-ML) has a molecular weight (MW) of 14.9 kDa as analyzed by SEC-MALS, suggesting that this protein is a monomer.

Bioactivity Recombinant Mouse IL-3 Protein Bioactivity View Larger

Recombinant Mouse IL-3 (Catalog # 403-ML) stimulates cell proliferation of the NFS-60 mouse myelogenous leukemia lymphoblast cell line. The ED50 for this effect is 20-100 pg/mL.

SDS-PAGE Recombinant Mouse IL-3 Protein SDS-PAGE View Larger

1 μg/lane of Recombinant Mouse IL-3 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 15 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background: IL-3

Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenitors. In addition, IL-3 also affects the functional activity of mature mast cells, basophils, eosinophils and macrophages. Because of its multiple functions and targets, it was originally studied under different names, including mast cell growth factor P-cell stimulating factor, burst promoting activity, multi-colony stimulating factor, thy-1 inducing factor and WEHI-3 growth factor. In addition to activated T cells, other cell types such as human thymic epithelial cells, activated mouse mast cells, mouse keratinocytes and neurons/astrocytes can also produce IL-3. At the amino acid sequence level, mature human and mouse IL-3 share only 29% sequence identity. Consistent with this lack of homology, IL-3 activity is highly species-specific and human IL-3 does not show activity on mouse cells.

IL-3 exerts its biological activities through binding to specific cell surface receptors. The high affinity receptor responsible for IL-3 signaling is composed of alpha and beta subunits. The IL-3R alpha is a member of the cytokine receptor super family and binds IL-3 with low affinity. Two distinct beta subunits, AIC2A ( beta IL-3) and AIC2B ( beta c) are present in mouse cells. beta IL-3 also binds IL-3 with low affinity and forms a high affinity receptor with the alpha subunit. The beta c subunits does not bind any cytokine but forms functional high affinity receptors with the alpha subunit of the IL-3, IL-5 and GM-CSF receptors. Receptors for IL-3 are present on bone marrow progenitors, macrophages, mast cells, eosinophils, megakaryocytes, basophils and various myeloid leukemic cells.

References
  1. Yokota, T. et al., 1984, Proc. Natl. Acad. Sci. USA 81:1070.
  2. Fung, M.C. et al., 1984, Nature 307:233.
  3. Miyatake, S. et al., 1985, Proc. Natl. Acad. Sci. USA 82:316.
Long Name
Interleukin 3
Entrez Gene IDs
3562 (Human); 16187 (Mouse); 24495 (Rat)
Alternate Names
Hematopoietic growth factor; IL3; IL-3; IL-3MGC79398; interleukin 3 (colony-stimulating factor, multiple); interleukin-3; Mast cell growth factor; mast-cell growth factor; MCGF; MCGFMGC79399; MULTI-CSF; multilineage-colony-stimulating factor; Multipotential colony-stimulating factor; P-cell stimulating factor; P-cell-stimulating factor

Citations for Recombinant Mouse IL-3 Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

178 Citations: Showing 1 - 10
Filter your results:

Filter by:

  1. SETDB1 suppresses NK cell-mediated immunosurveillance in acute myeloid leukemia with granulo-monocytic differentiation
    Authors: Chang, YH;Yamamoto, K;Fujino, T;Wang, TW;Sugimoto, E;Zhang, W;Yabushita, T;Suzaki, K;Pietsch, EC;Weir, BA;Crescenzo, R;Cowley, GS;Attar, R;Philippar, U;Wunderlich, M;Mizukawa, B;Zheng, Y;Enomoto, Y;Imai, Y;Kitamura, T;Goyama, S;
    Cell reports
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Constant surface area-to-volume ratio during cell growth as a design principle in mammalian cells
    Authors: Wu, W;Lam, AR;Suarez, K;Smith, GN;Duquette, SM;Yu, J;Mankus, D;Bisher, M;Lytton-Jean, A;Manalis, SR;Miettinen, TP;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Glycolytic state of aortic endothelium favors hematopoietic transition during the emergence of definitive hematopoiesis
    Authors: Pv, A;Mehatre, SH;Verfaillie, CM;Alam, MT;Khurana, S;
    Science advances
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  4. mTORC1 activity oscillates throughout the cell cycle promoting mitotic entry and differentially influencing autophagy induction
    Authors: Joshi, JN;Lerner, AD;Scallo, F;Grumet, AN;Matteson, P;Millonig, JH;Valvezan, AJ;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Type 3 secretion system induced leukotriene B4 synthesis by leukocytes is actively inhibited by Yersinia pestis to evade early immune recognition
    Authors: Brady, A;Sheneman, KR;Pulsifer, AR;Price, SL;Garrison, TM;Maddipati, KR;Bodduluri, SR;Pan, J;Boyd, NL;Zheng, JJ;Rai, SN;Hellmann, J;Haribabu, B;Uriarte, SM;Lawrenz, MB;
    PLoS pathogens
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Foretinib is effective in acute myeloid leukemia by inhibiting FLT3 and overcoming secondary mutations that drive resistance to quizartinib and gilteritinib
    Authors: Wang, P;Zhang, Y;Xiang, R;Yang, J;Xu, Y;Deng, T;Zhou, W;Wang, C;Xiao, X;Wang, S;
    Cancer research
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  7. Characterizations of a neutralizing antibody broadly reactive to multiple gluten peptide:HLA-DQ2.5 complexes in the context of celiac disease
    Authors: Okura, Y;Ikawa-Teranishi, Y;Mizoroki, A;Takahashi, N;Tsushima, T;Irie, M;Harfuddin, Z;Miura-Okuda, M;Ito, S;Nakamura, G;Takesue, H;Ozono, Y;Nishihara, M;Yamada, K;Gan, SW;Hayasaka, A;Ishii, S;Wakabayashi, T;Muraoka, M;Nagaya, N;Hino, H;Nemoto, T;Kuramochi, T;Torizawa, T;Shimada, H;Kitazawa, T;Okazaki, M;Nezu, J;Sollid, LM;Igawa, T;
    Nature communications
    Species: Mouse
    Sample Types: Transfected Whole Cells
    Applications: Bioassay
  8. Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner
    Authors: Luis, TC;Barkas, N;Carrelha, J;Giustacchini, A;Mazzi, S;Norfo, R;Wu, B;Aliouat, A;Guerrero, JA;Rodriguez-Meira, A;Bouriez-Jones, T;Macaulay, IC;Jasztal, M;Zhu, G;Ni, H;Robson, MJ;Blakely, RD;Mead, AJ;Nerlov, C;Ghevaert, C;Jacobsen, SEW;
    Nature communications
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Precision RNAi using synthetic shRNAmir target sites
    Authors: Hoffmann, T;Hörmann, A;Corcokovic, M;Zmajkovic, J;Hinterndorfer, M;Salkanovic, J;Spreitzer, F;Köferle, A;Gitschtaler, K;Popa, A;Oberndorfer, S;Andersch, F;Schaefer, M;Fellner, M;Budano, N;Ruppert, JG;Chetta, P;Wurm, M;Zuber, J;Neumüller, RA;
    eLife
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. IL-3 orchestrates ulcerative colitis pathogenesis by controlling the development and the recruitment of splenic reservoir neutrophils
    Authors: Bénard, A;Mittelstädt, A;Klösch, B;Glanz, K;Müller, J;Schoen, J;Nüse, B;Brunner, M;Naschberger, E;Stürzl, M;Mattner, J;Muñoz, LE;Sohn, K;Grützmann, R;Weber, GF;
    Cell reports
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Tissue Culture
  11. Nore1 inhibits age-associated myeloid lineage skewing and clonal hematopoiesis, but facilitates termination of emergency (stress) granulopoiesis
    Authors: Williams, O;Hu, L;Huang, W;Patel, P;Bartom, ET;Bei, L;Hjort, E;Hijiya, C;Eklund, EA;
    The Journal of biological chemistry
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. A Rapid, Functional sgRNA Screening Method for Generating Murine RET and NTRK1 Fusion Oncogenes
    Authors: L Schubert, AT Le, TK Hinz, A Navarro, SK Nelson-Tay, RA Nemenoff, LE Heasley, RC Doebele
    bioRxiv : the preprint server for biology, 2023-04-06;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. The RNA-binding protein hnRNP F is required for the germinal center B cell response
    Authors: H Huang, Y Li, G Zhang, GX Ruan, Z Zhu, W Chen, J Zou, R Zhang, J Wang, Y Ouyang, S Xu, X Ou
    Nature Communications, 2023-03-30;14(1):1731.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Latexin regulates sex dimorphism in hematopoiesis via gender-specific differential expression of microRNA 98-3p and thrombospondin 1
    Authors: X Cui, C Zhang, F Wang, X Zhao, S Wang, J Liu, D He, C Wang, FC Yang, S Tong, Y Liang
    Cell Reports, 2023-03-16;42(3):112274.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. PI3-kinase deletion promotes myelodysplasia by dysregulating autophagy in hematopoietic stem cells
    Authors: K Ames, I Kaur, Y Shi, MM Tong, T Sinclair, S Hemmati, SG Glushakow-, E Tein, L Gurska, U Steidl, R Dubin, J Shan, C Montagna, K Pradhan, A Verma, K Gritsman
    Science Advances, 2023-02-22;9(8):eade8222.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  16. IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
    Authors: X Liu, N Sato, T Yabushita, J Li, Y Jia, M Tamura, S Asada, T Fujino, T Fukushima, T Yonezawa, Y Tanaka, T Fukuyama, A Tsuchiya, S Shikata, H Iwamura, C Kinouchi, K Komatsu, S Yamasaki, T Shibata, AT Sasaki, J Schibler, M Wunderlich, E O'Brien, B Mizukawa, JC Mulloy, Y Sugiura, H Takizawa, T Shibata, K Miyake, T Kitamura, S Goyama
    Embo Molecular Medicine, 2022-12-01;0(0):e15631.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  17. Switch type I to type II TRK inhibitors for combating clinical resistance induced by xDFG mutation for cancer therapy
    Authors: S Xiang, J Wang, H Huang, Z Wang, X Song, Y Zhou, F Jin, X He, ZM Zhang, Z Tu, K Ding, Z Zhang, X Lu
    European Journal of Medicinal Chemistry, 2022-11-12;245(0):114899.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Mast cell regranulation requires a metabolic switch involving mTORC1 and a glucose-6-phosphate transporter
    Authors: JA Iskarpatyo, J Shi, MA Abraham, APS Rathore, Y Miao, SN Abraham
    Cell Reports, 2022-09-27;40(13):111346.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  19. IL-3 regulates the differentiation of pathogenic Th17 cells
    Authors: L Rani, A Kumar, J Karhade, G Pandey, A Guha, GC Mishra, MR Wani
    European Journal of Immunology, 2022-09-26;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Erythropoietin-driven dynamic proteome adaptations during erythropoiesis prevent iron overload in the developing embryo
    Authors: S Chakrabort, G Andrieux, P Kastl, L Adlung, S Altamura, ME Boehm, LE Schwarzmül, Y Abdullah, MC Wagner, B Helm, HJ Gröne, WD Lehmann, M Boerries, H Busch, MU Muckenthal, M Schilling, U Klingmülle
    Cell Reports, 2022-09-20;40(12):111360.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Efficient transdermal delivery of functional protein cargoes by a hydrophobic peptide MTD�1067
    Authors: HJ Shin, SU Bak, HN La, JS Kang, HH Lee, HJ Eom, BK Lee, HA Kang
    Oncogene, 2022-06-27;12(1):10853.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Single-cell analysis identifies the interaction of altered renal tubules with basophils orchestrating kidney fibrosis
    Authors: T Doke, A Abedini, DL Aldridge, YW Yang, J Park, CM Hernandez, MS Balzer, R Shrestra, G Coppock, JMI Rico, SY Han, J Kim, S Xin, AM Piliponsky, M Angelozzi, V Lefebvre, MC Siracusa, CA Hunter, K Susztak
    Nature Immunology, 2022-05-12;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  23. MDS cells impair osteolineage differentiation of MSCs via extracellular vesicles to suppress normal hematopoiesis
    Authors: Y Hayashi, KC Kawabata, Y Tanaka, Y Uehara, Y Mabuchi, K Murakami, A Nishiyama, S Kiryu, Y Yoshioka, Y Ota, T Sugiyama, K Mikami, M Tamura, T Fukushima, S Asada, R Takeda, Y Kunisaki, T Fukuyama, K Yokoyama, T Uchida, M Hagihara, N Ohno, K Usuki, A Tojo, Y Katayama, S Goyama, F Arai, T Tamura, T Nagasawa, T Ochiya, D Inoue, T Kitamura
    Cell Reports, 2022-05-10;39(6):110805.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. IL-3-Induced Immediate Expression of c-fos and c-jun Is Modulated by the IKK2-JNK Axis
    Authors: H Fujita, T Fujita, H Fujii
    Cells, 2022-04-25;11(9):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Distinct resistance mechanisms arise to allosteric vs. ATP-competitive AKT inhibitors
    Authors: KMZ Savill, BB Lee, J Oeh, J Lin, E Lin, WJ Chung, A Young, W Chen, M Mi?, K Mesh, J Eastham, F Gnad, Z Jiang, EW Stawiski, B Haley, A Daemen, X Wang, H Koeppen, Z Modrusan, SE Martin, D Sampath, K Lin
    Nature Communications, 2022-04-19;13(1):2057.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. A functional genomic approach to actionable gene fusions for precision oncology
    Authors: J Li, H Lu, PK Ng, A Pantazi, CKM Ip, KJ Jeong, B Amador, R Tran, YH Tsang, L Yang, X Song, T Dogruluk, X Ren, A Hadjipanay, CA Bristow, S Lee, M Kucherlapa, M Parfenov, J Tang, S Seth, HS Mahadeshwa, K Mojumdar, D Zeng, J Zhang, A Protopopov, JG Seidman, CJ Creighton, Y Lu, N Sahni, KR Shaw, F Meric-Bern, A Futreal, L Chin, KL Scott, R Kucherlapa, GB Mills, H Liang
    Science Advances, 2022-02-09;8(6):eabm2382.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Mosaic loss of chromosome Y promotes leukemogenesis and clonal hematopoiesis
    Authors: Q Zhang, L Zhao, Y Yang, S Li, Y Liu, C Chen
    JCI Insight, 2022-02-08;7(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Multiplex genome editing of mammalian cells for producing recombinant heparin
    Authors: BE Thacker, KJ Thorne, C Cartwright, J Park, K Glass, A Chea, BP Kellman, NE Lewis, Z Wang, A Di Nardo, ST Sharfstein, W Jeske, J Walenga, J Hogwood, E Gray, B Mulloy, JD Esko, CA Glass
    Metabolic engineering, 2022-01-14;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Leukemic progenitor cells enable immunosuppression and post-chemotherapy relapse via IL-36-inflammatory monocyte axis
    Authors: HZ Guo, ZH Guo, SH Yu, LT Niu, WT Qiang, MM Huang, YY Tian, J Chen, H Yang, XQ Weng, Y Zhang, W Zhang, SY Hu, J Shi, J Zhu
    Science Advances, 2021-10-08;7(41):eabg4167.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Rational design of heterodimeric receptors capable of activating target signaling molecules
    Authors: T Kongkrongt, R Zhang, M Kawahara
    Scientific Reports, 2021-08-19;11(1):16809.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Activated interleukin-7 receptor signaling drives B-cell acute lymphoblastic leukemia in mice
    Authors: KR Thomas, EJ Allenspach, ND Camp, MN Wray-Dutra, S Khim, A Zielinska-, AE Timms, JP Loftus, HD Liggitt, K Georgopoul, SK Tasian, RG James, DJ Rawlings
    Leukemia, 2021-06-30;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. GLT1 gene delivery based on bone marrow-derived cells ameliorates motor function and survival in a mouse model of ALS
    Authors: N Ohashi, T Terashima, M Katagi, Y Nakae, J Okano, Y Suzuki, H Kojima
    Scientific Reports, 2021-06-17;11(1):12803.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  33. Evolution of KIPPIS as a versatile platform for evaluating intracellularly functional peptide aptamers
    Authors: D Kashima, M Kawahara
    Scientific Reports, 2021-06-03;11(1):11758.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  34. HOXA11 plays critical roles in disease progression and response to cytarabine in AML
    Authors: JF Fu, LY Shih, TH Yen
    Oncology reports, 2021-06-03;46(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  35. MLKL promotes cellular differentiation in myeloid leukemia by facilitating the release of G-CSF
    Authors: X Wang, U Ros, D Agrawal, EC Keller, J Slotta-Hus, V Dill, B Shen, R Shi, T Herold, C Belka, R Misra, F Bassermann, AJ Garcia-Sae, PJ Jost
    Cell Death and Differentiation, 2021-06-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. The balance between the intronic miR-342 and its host gene Evl determines hematopoietic cell fate decision
    Authors: F Herbst, TJL Lang, ESP Eckert, P Wünsche, AA Wurm, T Kindinger, K Laaber, S Hemmati, A Hotz-Wagen, O Zavidij, A Paruzynski, J Lu, C von Kalle, T Zenz, C Klein, M Schmidt, CR Ball, H Glimm
    Leukemia, 2021-05-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Small-molecule inhibitor targeting the Hsp70-Bim protein-protein interaction in CML cells overcomes BCR-ABL-independent TKI resistance
    Authors: T Song, Y Guo, Z Xue, Z Guo, Z Wang, D Lin, H Zhang, H Pan, X Zhang, F Yin, H Wang, LB Uwituze, Z Zhang
    Leukemia, 2021-05-18;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. A novel Hsp70 inhibitor specifically targeting the cancer-related Hsp70-Bim protein-protein interaction
    Authors: Z Wang, T Song, Z Guo, LB Uwituze, Y Guo, H Zhang, H Wang, X Zhang, H Pan, T Ji, F Yin, S Zhou, J Dai, Z Zhang
    European Journal of Medicinal Chemistry, 2021-04-14;220(0):113452.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Myocyte-specific enhancer factor 2c triggers transdifferentiation of adipose tissue-derived stromal cells into spontaneously beating cardiomyocyte-like cells
    Authors: S Takashima, S Usui, O Inoue, C Goten, K Yamaguchi, Y Takeda, S Cui, Y Sakai, K Hayashi, K Sakata, MA Kawashiri, M Takamura
    Scientific Reports, 2021-01-15;11(1):1520.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. SNAP23 is essential for platelet and mast cell development and required in connective tissue mast cells for anaphylaxis
    Authors: RA Cardenas, R Gonzalez, E Sanchez, MA Ramos, EI Cardenas, AI Rodarte, RJ Alcazar-Fe, A Isaza, AR Burns, R Heidelberg, R Adachi
    The Journal of Biological Chemistry, 2021-01-08;296(0):100268.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  41. Airway-Associated Macrophages in Homeostasis and Repair
    Authors: AE Engler, AB Ysasi, RMF Pihl, C Villacorta, HM Heston, HMK Richardson, BR Thapa, NR Moniz, AC Belkina, SA Mazzilli, JR Rock
    Cell Reports, 2020-12-29;33(13):108553.
    Species: Transgenic Mouse
    Sample Types: Spheroid
    Applications: Bioassay
  42. In vitro and in vivo characterization of Recifercept, a soluble fibroblast growth factor receptor 3, as treatment for achondroplasia
    Authors: D Gonçalves, G Rignol, P Dellugat, G Hartmann, S Sarrazy Ga, J Stavenhage, L Santarelli, E Gouze, C Czech
    PLoS ONE, 2020-12-28;15(12):e0244368.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Authentication of Primary Murine Cell Lines by a Microfluidics-Based Lab-On-Chip System
    Authors: Y Hong, N Singh, S Bamopoulos, E Gjerga, LK Schmalbroc, K Balabanian, M Schick, U Keller, M Wirth
    Biomedicines, 2020-12-09;8(12):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. In Vivo Pre-Instructed HSCs Robustly Execute Asymmetric Cell Divisions In Vitro
    Authors: M Girotra, V Trachsel, A Roch, MP Lutolf
    Int J Mol Sci, 2020-11-03;21(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Monitoring and modeling of lymphocytic leukemia cell bioenergetics reveals decreased ATP synthesis during cell division
    Authors: JH Kang, G Katsikis, Z Li, KM Sapp, MA Stockslage, D Lim, MG Vander Hei, MB Yaffe, SR Manalis, TP Miettinen
    Nat Commun, 2020-10-05;11(1):4983.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Covalent inhibition of NSD1 histone methyltransferase
    Authors: H Huang, CA Howard, S Zari, HJ Cho, S Shukla, H Li, J Ndoj, P González-A, C Nikolaidis, J Abbott, DS Rogawski, MA Potopnyk, K Kempinska, H Miao, T Purohit, A Henderson, A Mapp, ML Sulis, A Ferrando, J Grembecka, T Cierpicki
    Nat. Chem. Biol., 2020-08-31;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Basophils prime group 2 innate lymphoid cells for neuropeptide-mediated inhibition
    Authors: JM Inclan-Ric, JJ Ponessa, N Valero-Pac, CM Hernandez, CB Sy, AD Lemenze, AM Beaulieu, MC Siracusa
    Nat. Immunol., 2020-08-17;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Bioassay
  48. Butyrophilin-like proteins display combinatorial diversity in selecting and maintaining signature intraepithelial &gamma&delta T cell compartments
    Authors: A Jandke, D Melandri, L Monin, DS Ushakov, AG Laing, P Vantourout, P East, T Nitta, T Narita, H Takayanagi, R Feederle, A Hayday
    Nat Commun, 2020-07-28;11(1):3769.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  49. Chemical synthesis of a sulfated d-glucosamine library and evaluation of cell proliferation capabilities
    Authors: A Ní Chealla, SE Guimond, S Oscarson, GJ Miller
    Carbohydr. Res., 2020-07-12;495(0):108085.
    Species: Mouse
    Sample Types: Transfected Whole Cells
    Applications: Bioassay
  50. Streamlined human antibody generation and optimization by exploiting designed immunoglobulin loci in a B cell line
    Authors: H Seo, H Masuda, K Asagoshi, T Uchiki, S Kawata, G Sasaki, T Yabuki, S Miyai, N Takahashi, SI Hashimoto, A Sawada, A Takaiwa, C Koyama, K Tamai, K Kurosawa, KY Lin, K Ohta, Y Nakazaki
    Cell. Mol. Immunol., 2020-05-26;0(0):.
    Species: Mouse
    Sample Types:
    Applications: Cell Culture
  51. Existence of reprogrammed lymphoma stem cells in a murine ALCL-like model
    Authors: S Kreutmair, C Klingeberg, T Poggio, G Andrieux, A Keller, C Miething, M Follo, D Pfeifer, K Shoumariye, C Lengerke, I Gonzalez-M, F Fend, R Zeiser, SD Turner, L Quintanill, M Boerries, J Duyster, AL Illert
    Leukemia, 2020-03-17;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  52. Genetic basis for iMCD-TAFRO
    Authors: A Yoshimi, TM Trippett, N Zhang, X Chen, AV Penson, ME Arcila, J Pichardo, J Baik, A Sigler, H Harada, DC Fajgenbaum, A Dogan, O Abdel-Waha, W Xiao
    Oncogene, 2020-02-12;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Ribonucleotide reductase inhibitors suppress SAMHD1 ara-CTPase activity enhancing cytarabine efficacy
    Authors: SG Rudd, N Tsesmetzis, K Sanjiv, CB Paulin, L Sandhow, J Kutzner, I Hed Myrber, SS Bunten, H Axelsson, SM Zhang, A Rasti, P Mäkelä, SA Coggins, S Tao, S Suman, RM Branca, G Mermelekas, E Wiita, S Lee, J Walfridsso, RF Schinazi, B Kim, J Lehtiö, GZ Rassidakis, K Pokrovskaj, U Warpman-Be, M Heyman, D Grandér, S Lehmann, T Lundbäck, H Qian, JI Henter, T Schaller, T Helleday, N Herold
    EMBO Mol Med, 2020-01-17;12(3):e10419.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  54. Divergent effects of Wnt5b on IL-3- and GM-CSF-induced myeloid differentiation
    Authors: MM de Rezende, JP Ng-Blichfe, GZ Justo, EJ Paredes-Ga, R Gosens
    Cell. Signal., 2019-12-17;67(0):109507.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium
    Authors: T Fukushima, Y Tanaka, FK Hamey, CH Chang, T Oki, S Asada, Y Hayashi, T Fujino, T Yonezawa, R Takeda, KC Kawabata, T Fukuyama, T Umemoto, K Takubo, H Takizawa, S Goyama, Y Ishihama, H Honda, B Göttgens, T Kitamura
    Cell Rep, 2019-12-17;29(12):4144-4158.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  56. Effect of Fms-like tyrosine kinase 3 (FLT3) ligand (FL) on antitumor activity of gilteritinib, a FLT3 inhibitor, in mice xenografted with FL-overexpressing cells
    Authors: T Kawase, T Nakazawa, T Eguchi, H Tsuzuki, Y Ueno, Y Amano, T Suzuki, M Mori, T Yoshida
    Oncotarget, 2019-10-22;10(58):6111-6123.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis
    Authors: A Yoshimi, KT Lin, DH Wiseman, MA Rahman, A Pastore, B Wang, SC Lee, JB Micol, XJ Zhang, S de Botton, V Penard-Lac, EM Stein, H Cho, RE Miles, D Inoue, TR Albrecht, TCP Somervaill, K Batta, F Amaral, F Simeoni, DP Wilks, C Cargo, AM Intlekofer, RL Levine, H Dvinge, RK Bradley, EJ Wagner, AR Krainer, O Abdel-Waha
    Nature, 2019-10-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  58. Secretion of Mast Cell Inflammatory Mediators Is Enhanced by CADM1-Dependent Adhesion to Sensory Neurons
    Authors: R Magadmi, J Meszaros, ZA Damanhouri, EP Seward
    Front Cell Neurosci, 2019-06-18;13(0):262.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Lipocalin 2: A New Antimicrobial in Mast Cells
    Authors: YL Chang, Z Wang, S Igawa, JE Choi, T Werbel, A Di Nardo
    Int J Mol Sci, 2019-05-14;20(10):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  60. Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC
    Authors: C Li, L Dong, R Su, Y Bi, Y Qing, X Deng, Y Zhou, C Hu, M Yu, H Huang, X Jiang, X Li, X He, D Zou, C Shen, L Han, M Sun, J Skibbe, K Ferchen, X Qin, H Weng, H Huang, C Song, J Chen, J Jin
    Haematologica, 2019-04-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  61. The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4
    Authors: N Funk, M Munz, T Ott, K Brockmann, A Wenninger-, R Kühn, D Vogt-Weise, F Giesert, W Wurst, T Gasser, S Biskup
    Sci Rep, 2019-03-14;9(1):4515.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Japanese encephalitis virus neuropenetrance is driven by mast cell chymase
    Authors: JT Hsieh, APS Rathore, G Soundaraja, AL St John
    Nat Commun, 2019-02-11;10(1):706.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. Selective hematopoietic stem cell ablation using CD117-antibody-drug-conjugates enables safe and effective transplantation with immunity preservation
    Authors: A Czechowicz, R Palchaudhu, A Scheck, Y Hu, J Hoggatt, B Saez, WW Pang, MK Mansour, TA Tate, YY Chan, E Walck, G Wernig, JA Shizuru, F Winau, DT Scadden, DJ Rossi
    Nat Commun, 2019-02-06;10(1):617.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Age-related differences in the bone marrow stem cell niche generate specialized microenvironments for the distinct regulation of normal hematopoietic and leukemia stem cells
    Authors: GY Lee, SY Jeong, HR Lee, IH Oh
    Sci Rep, 2019-01-30;9(1):1007.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Rps14, Csnk1a1 and miRNA145/miRNA146a deficiency cooperate in the clinical phenotype and activation of the innate immune system in the 5q- syndrome
    Authors: F Ribezzo, IAM Snoeren, S Ziegler, J Stoelben, PA Olofsen, A Henic, MV Ferreira, S Chen, USA Stalmann, G Buesche, RM Hoogenboez, R Kramann, U Platzbecke, MHGP Raaijmaker, BL Ebert, RK Schneider
    Leukemia, 2019-01-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Botulinum toxin blocks mast cells and prevents rosacea like inflammation
    Authors: JE Choi, T Werbel, Z Wang, CC Wu, TL Yaksh, A Di Nardo
    J. Dermatol. Sci., 2018-12-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Syntaxin 3, but not Syntaxin 4, is required for mast cell regulated exocytosis, where it plays a primary role mediating compound exocytosis
    Authors: E Sanchez, EA Gonzalez, DS Moreno, RA Cardenas, MA Ramos, AJ Davalos, J Manllo, AI Rodarte, Y Petrova, DC Moreira, MA Chavez, A Tortoriell, A Lara, BA Gutierrez, AR Burns, R Heidelberg, R Adachi
    J. Biol. Chem., 2018-12-18;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Therapeutic Vulnerabilities in FLT3-Mutant AML Unmasked by Palbociclib
    Authors: IZ Uras, B Maurer, S Nebenfuehr, M Zojer, P Valent, V Sexl
    Int J Mol Sci, 2018-12-11;19(12):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  69. Mast cells are essential intermediaries in regulating IL-33/ST2 signaling for an immune network favorable to mucosal healing in experimentally inflamed colons
    Authors: Z He, J Song, J Hua, M Yang, Y Ma, T Yu, J Feng, B Liu, X Wang, Y Li, J Li
    Cell Death Dis, 2018-12-05;9(12):1173.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Linking single-cell measurements of mass, growth rate, and gene expression
    Authors: RJ Kimmerling, SM Prakadan, AJ Gupta, NL Calistri, MM Stevens, S Olcum, N Cermak, RS Drake, K Pelton, F De Smet, KL Ligon, AK Shalek, SR Manalis
    Genome Biol., 2018-11-27;19(1):207.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  71. Brief Exposure of Skin to Near-Infrared Laser Modulates Mast Cell Function and Augments the Immune Response
    Authors: Y Kimizuka, W Katagiri, JJ Locascio, A Shigeta, Y Sasaki, M Shibata, K Morse, RF Sîrbulescu, M Miyatake, P Reeves, M Suematsu, J Gelfand, T Brauns, MC Poznansky, K Tsukada, S Kashiwagi
    J. Immunol., 2018-11-12;0(0):.
    Species: Mouse
    Sample Types:
    Applications: Cell Culture
  72. ASXL1 and SETBP1 mutations promote leukaemogenesis by repressing TGF? pathway genes through histone deacetylation
    Authors: M Saika, D Inoue, R Nagase, N Sato, A Tsuchiya, T Yabushita, T Kitamura, S Goyama
    Sci Rep, 2018-10-26;8(1):15873.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Biological and epidemiological evidence of anti-allergic effects of traditional Japanese food ume (Prunus mume)
    Authors: R Kono, M Nakamura, S Nomura, N Kitano, T Kagiya, Y Okuno, KI Inada, A Tokuda, H Utsunomiya, M Ueno
    Sci Rep, 2018-08-03;8(1):11638.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  74. The histone chaperone NAP1L3 is required for haematopoietic stem cell maintenance and differentiation
    Authors: Y Heshmati, S Kharazi, G Türköz, D Chang, E Kamali Dol, J Boström, A Krstic, T Boukoura, E Wagner, N Kadri, R Månsson, M Altun, H Qian, J Walfridsso
    Sci Rep, 2018-07-25;8(1):11202.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Mapping Active Gene-Regulatory Regions in Human Repopulating Long-Term HSCs
    Authors: P Wünsche, ESP Eckert, T Holland-Le, A Paruzynski, A Hotz-Wagen, R Fronza, T Rath, I Gil-Farina, M Schmidt, C von Kalle, C Klein, CR Ball, F Herbst, H Glimm
    Cell Stem Cell, 2018-07-05;23(1):132-146.e9.
  76. Iron overload impairs normal hematopoietic stem and progenitor cells through reactive oxygen species and shortens survival in myelodysplastic syndrome mice
    Authors: X Jin, X He, X Cao, P Xu, Y Xing, S Sui, L Wang, J Meng, W Lu, R Cui, H Ni, M Zhao
    Haematologica, 2018-06-14;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  77. Interleukin-9 promotes early mast cell-mediated expulsion of Strongyloides ratti but is dispensable for generation of protective memory
    Authors: M Reitz, W Hartmann, N Rüdiger, Z Orinska, ML Brunn, M Breloer
    Sci Rep, 2018-06-05;8(1):8636.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Loss of the Liver X Receptors Disrupts the Balance of Hematopoietic Populations, With Detrimental Effects on Endothelial Progenitor Cells
    Authors: A Rasheed, R Tsai, CL Cummins
    J Am Heart Assoc, 2018-05-08;7(10):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Allogeneic transplantation of programmable cells of monocytic origin (PCMO) improves angiogenesis and tissue recovery in critical limb ischemia (CLI): a translational approach
    Authors: R Berndt, L Hummitzsch, K He beta, M Albrecht, K Zitta, R Rusch, B Sarras, A Bayer, J Cremer, F Faendrich, J Gro beta
    Stem Cell Res Ther, 2018-04-27;9(1):117.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Mechanisms and clinical activity of an EGFR and HER2 exon 20-selective kinase inhibitor in non-small cell lung cancer
    Authors: JP Robichaux, YY Elamin, Z Tan, BW Carter, S Zhang, S Liu, S Li, T Chen, A Poteete, A Estrada-Be, AT Le, A Truini, MB Nilsson, H Sun, E Roarty, SB Goldberg, JR Brahmer, M Altan, C Lu, V Papadimitr, K Politi, RC Doebele, KK Wong, JV Heymach
    Nat. Med., 2018-04-23;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Functional relevance of in vivo half antibody exchange of an IgG4 therapeutic antibody-drug conjugate
    Authors: P Herbener, K Schönfeld, M König, M Germer, JM Przyborski, K Bernöster, J Schüttrump
    PLoS ONE, 2018-04-19;13(4):e0195823.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  82. Global H3.3 dynamic deposition defines its bimodal role in cell fate transition
    Authors: HT Fang, CA El Farran, QR Xing, LF Zhang, H Li, B Lim, YH Loh
    Nat Commun, 2018-04-18;9(1):1537.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Expression of mutant Asxl1 perturbs hematopoiesis and promotes susceptibility to leukemic transformation
    Authors: R Nagase, D Inoue, A Pastore, T Fujino, HA Hou, N Yamasaki, S Goyama, M Saika, A Kanai, Y Sera, S Horikawa, Y Ota, S Asada, Y Hayashi, KC Kawabata, R Takeda, HF Tien, H Honda, O Abdel-Waha, T Kitamura
    J. Exp. Med., 2018-04-11;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Munc18-2, but not Munc18-1 or Munc18-3, controls compound and single-vesicle regulated exocytosis in mast cells
    Authors: BA Gutierrez, MA Chavez, AI Rodarte, M Ramos, A Dominguez, Y Petrova, AJ Davalos, RM Costa, R Elizondo, MJ Tuvim, BF Dickey, AR Burns, R Heidelberg, R Adachi
    J. Biol. Chem., 2018-03-29;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  85. A Study and Review of Effects of Botulinum Toxins on Mast Cell Dependent and Independent Pruritus
    Authors: R Ramachandr, MJ Marino, S Paul, Z Wang, NL Mascarenha, S Pellett, EA Johnson, A DiNardo, TL Yaksh
    Toxins (Basel), 2018-03-23;10(4):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation, Differentiation
  86. A safety and immunogenicity study of immunization with hVEGF26-104/RFASE in cynomolgus monkeys
    Authors: MQ Wentink, HMW Verheul, AW Griffioen, KA Schafer, S McPherson, RJ Early, HJ van der Vl, TD de Gruijl
    Vaccine, 2018-03-05;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  87. The E3 ubiquitin ligase Triad1 influences development of Mll-Ell-induced acute myeloid leukemia
    Authors: H Wang, L Bei, CA Shah, W Huang, LC Platanias, EA Eklund
    Oncogene, 2018-02-20;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  88. An unexpected protective role of low affinity allergen-specific IgG via the inhibitory receptor Fc?RIIb
    Authors: M Bachmann, M Vogel, L Zha, F Leoratti, L He, MO Mohsen, F Storni, M Cragg
    J. Allergy Clin. Immunol., 2018-01-31;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  89. RASSF1A uncouples Wnt from Hippo signalling and promotes YAP mediated differentiation via p73
    Authors: A Papaspyrop, L Bradley, A Thapa, CY Leung, K Toskas, D Koennig, DE Pefani, C Raso, C Grou, G Hamilton, N Vlahov, A Grawenda, S Haider, J Chauhan, L Buti, A Kanapin, X Lu, F Buffa, G Dianov, A von Kriegs, D Matallanas, A Samsonova, M Zernicka-G, E O'Neill
    Nat Commun, 2018-01-30;9(1):424.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  90. E2F1 Suppresses Oxidative Metabolism and Endothelial Differentiation of Bone Marrow Progenitor Cells
    Authors: S Xu, J Tao, L Yang, E Zhang, C Boriboun, J Zhou, T Sun, M Cheng, K Huang, J Shi, N Dong, Q Liu, TC Zhao, H Qiu, RA Harris, N Chandel, DW Losordo, G Qin
    Circ. Res., 2018-01-22;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  91. Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia
    Authors: X Jiang, C Hu, K Ferchen, J Nie, X Cui, CH Chen, L Cheng, Z Zuo, W Seibel, C He, Y Tang, JR Skibbe, M Wunderlich, WC Reinhold, L Dong, C Shen, S Arnovitz, B Ulrich, J Lu, H Weng, R Su, H Huang, Y Wang, C Li, X Qin, J Mulloy, Y Zheng, J Diao, J Jin, C Li, PP Liu, C He, Y Chen, J Chen
    Nat Commun, 2017-12-13;8(1):2099.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  92. Chemical analyses and in vitro and in vivo toxicity of fruit methanol extract of Sechium edule var. nigrum spinosum
    Authors: I Aguiñiga-S, J Cadena-Íñi, E Santiago-O, G Gómez-Garc, VM Mendoza-Nú, J Rosado-Pér, M Ruíz-Ramos, VM Cisneros-S, E Ledesma-Ma, AJ Delgado-Bo, RM Soto-Herná
    Pharm Biol, 2017-12-01;55(1):1638-1645.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Funiculosin variants and phosphorylated derivatives promote innate immune responses via the Toll-like receptor 4/myeloid differentiation factor-2 complex
    Authors: N Okamoto, K Mizote, H Honda, A Saeki, Y Watanabe, T Yamaguchi-, R Fukui, N Tanimura, Y Motoi, S Akashi-Tak, T Kato, S Fujishita, T Kimura, U Ohto, T Shimizu, T Hirokawa, K Miyake, K Fukase, Y Fujimoto, Y Nagai, K Takatsu
    J. Biol. Chem., 2017-07-28;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Proteomic and Metabolomic Characterization of a Mammalian Cellular Transition from Quiescence to Proliferation
    Authors: HJ Lee, MP Jedrychows, A Vinayagam, N Wu, N Shyh-Chang, Y Hu, C Min-Wen, JK Moore, JM Asara, CA Lyssiotis, N Perrimon, SP Gygi, LC Cantley, MW Kirschner
    Cell Rep, 2017-07-18;20(3):721-736.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Massively parallel nanowell-based single-cell gene expression profiling
    Authors: LD Goldstein, YJ Chen, J Dunne, A Mir, H Hubschle, J Guillory, W Yuan, J Zhang, J Stinson, B Jaiswal, KB Pahuja, I Mann, T Schaal, L Chan, S Anandakris, CW Lin, P Espinoza, S Husain, H Shapiro, K Swaminatha, S Wei, M Srinivasan, S Seshagiri, Z Modrusan
    BMC Genomics, 2017-07-07;18(1):519.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  96. Interaction of primary mast cells with Borrelia burgdorferi (sensu stricto): role in transmission and dissemination in C57BL/6 mice
    Authors: Q Bernard, Z Wang, A Di Nardo, N Boulanger
    Parasit Vectors, 2017-06-27;10(1):313.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Lipopolysaccharide/TLR4 Stimulates IL-13 Production through a MyD88-BLT2-Linked Cascade in Mast Cells, Potentially Contributing to the Allergic Response
    Authors: AJ Lee, M Ro, KJ Cho, JH Kim
    J. Immunol., 2017-06-09;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  98. A novel, somatic, transforming mutation in the extracellular domain of Epidermal Growth Factor Receptor identified in myeloproliferative neoplasm
    Authors: DA Casolari, T Nguyen, CM Butcher, DG Iarossi, CN Hahn, SC Bray, P Neufing, WT Parker, J Feng, KZY Maung, A Wee, L Vidovic, CH Kok, PG Bardy, S Branford, ID Lewis, SW Lane, HS Scott, DM Ross, RJ D'Andrea
    Sci Rep, 2017-05-26;7(1):2467.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Engineering and Functional Characterization of Fusion Genes Identifies Novel Oncogenic Drivers of Cancer
    Authors: H Lu, N Villafane, T Dogruluk, CL Grzeskowia, K Kong, YH Tsang, O Zagorodna, A Pantazi, L Yang, NJ Neill, YW Kim, CJ Creighton, RG Verhaak, GB Mills, P Park, RS Kucherlapa, KL Scott
    Cancer Res., 2017-05-16;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  100. Generation and characterization of an antagonistic monoclonal antibody against an extracellular domain of mouse DP2 (CRTH2/GPR44) receptors for prostaglandin D2
    Authors: N Nagata, H Iwanari, H Kumagai, O Kusano-Ara, Y Ikeda, K Aritake, T Hamakubo, Y Urade
    PLoS ONE, 2017-04-10;12(4):e0175452.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  101. A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors
    Authors: A Itoh-Nakad, M Matsumoto, H Kato, J Sasaki, Y Uehara, Y Sato, R Ebina-Shib, M Morooka, R Funayama, K Nakayama, K Ochiai, A Muto, K Igarashi
    Cell Rep, 2017-03-07;18(10):2401-2414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Acquired resistance to LY2874455 in FGFR2-amplified gastric cancer through an emergence of novel FGFR2-ACSL5 fusion
    Authors: SY Kim, T Ahn, H Bang, JS Ham, J Kim, ST Kim, J Jang, M Shim, SY Kang, SH Park, BH Min, H Lee, WK Kang, KM Kim, W Park, J Lee
    Oncotarget, 2017-02-28;8(9):15014-15022.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Mesenchymal Cell Reprogramming in Experimental MPLW515L Mouse Model of Myelofibrosis
    Authors: Y Han, L Yue, M Wei, X Ren, Z Shao, L Zhang, RL Levine, PK Epling-Bur
    PLoS ONE, 2017-01-30;12(1):e0166014.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Radiation Induced Apoptosis of Murine Bone Marrow Cells Is Independent of Early Growth Response 1 (EGR1)
    Authors: KZ Oben, BW Gachuki, SS Alhakeem, MK McKenna, Y Liang, DK St Clair, VM Rangnekar, S Bondada
    PLoS ONE, 2017-01-12;12(1):e0169767.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Basophils promote tumor rejection via chemotaxis and infiltration of CD8+ T cells
    Cancer Res., 2016-11-22;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Reprogramming mouse fibroblasts into engraftable myeloerythroid and lymphoid progenitors
    Nat Commun, 2016-11-21;7(0):13396.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  107. Pot1 OB-fold mutations unleash telomere instability to initiate tumorigenesis
    Oncogene, 2016-11-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Time-Course Statistical Evaluation of Intercellular Adhesion Maturation by Femtosecond Laser Impulse
    Authors: Yoichiroh Hosokawa
    Biophys. J., 2016-11-15;111(10):2255-2262.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Cycloheximide Can Induce Bax/Bak Dependent Myeloid Cell Death Independently of Multiple BH3-Only Proteins
    PLoS ONE, 2016-11-02;11(11):e0164003.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Therapeutic Targeting of the G-CSF Receptor Reduces Neutrophil Trafficking and Joint Inflammation in Antibody-Mediated Inflammatory Arthritis
    Authors: Arna E Andrews
    J. Immunol., 2016-11-02;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Mast cell desensitization inhibits calcium flux and aberrantly remodels actin
    J Clin Invest, 2016-09-26;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Chronic myelogenous leukemia initiating cells require Polycomb group protein EZH2
    Cancer Discov, 2016-09-14;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  113. A functional bioassay to determine the activity of anti-VEGF antibody therapy in blood of patients with cancer
    Br J Cancer, 2016-08-30;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  114. Quantitative trait gene Slit2 positively regulates murine hematopoietic stem cell numbers
    Sci Rep, 2016-08-09;6(0):31412.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  115. Murine iPSC-Derived Macrophages as a Tool for Disease Modeling of Hereditary Pulmonary Alveolar Proteinosis due to Csf2rb Deficiency
    Stem Cell Reports, 2016-07-21;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Gene Therapy Induces Antigen-Specific Tolerance in Experimental Collagen-Induced Arthritis
    PLoS ONE, 2016-05-09;11(5):e0154630.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  117. iNKT Cells Are Responsible for the Apoptotic Reduction of Basophils That Mediate Th2 Immune Responses Elicited by Papain in Mice Following ?PGA Stimulation
    Authors: HJ Park, SW Lee, SH Park, S Hong
    PLoS ONE, 2016-04-06;11(4):e0152189.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  118. CD252 regulates mast cell mediated, CD1d-restricted NKT-cell activation in mice.
    Authors: Gonzalez Roldan N, Orinska Z, Ewers H, Bulfone-Paus S
    Eur J Immunol, 2015-12-09;46(2):432-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Prevention of Lethal Murine Hypophosphatasia by Neonatal Ex Vivo Gene Therapy Using Lentivirally Transduced Bone Marrow Cells
    Authors: O Iijima, K Miyake, A Watanabe, N Miyake, T Igarashi, C Kanokoda, A Nakamura-T, H Kinoshita, T Noguchi, S Abe, S Narisawa, JL Millán, T Okada, T Shimada
    Hum. Gene Ther, 2015-11-19;26(12):801-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  120. Mouse Resistin (mRetn): cloning, expression and purification in Escherichia coli and the potential regulative effects on murine bone marrow hematopoiesis.
    Authors: Wang F, Gao J, Malisani A, Xi X, Han W, Wan X
    BMC Biotechnol, 2015-11-16;15(0):105.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  121. Ubiquitous Over-Expression of Chromatin Remodeling Factor SRG3 Ameliorates the T Cell-Mediated Exacerbation of EAE by Modulating the Phenotypes of both Dendritic Cells and Macrophages.
    Authors: Lee S, Park H, Jeon S, Lee C, Seong R, Park S, Hong S
    PLoS ONE, 2015-07-06;10(7):e0132329.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  122. Coordinate regulation of residual bone marrow function by paracrine trafficking of AML exosomes.
    Authors: Huan J, Hornick N, Goloviznina N, Kamimae-Lanning A, David L, Wilmarth P, Mori T, Chevillet J, Narla A, Roberts C, Loriaux M, Chang B, Kurre P
    Leukemia, 2015-06-25;29(12):2285-95.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Angptl4 is upregulated under inflammatory conditions in the bone marrow of mice, expands myeloid progenitors, and accelerates reconstitution of platelets after myelosuppressive therapy.
    Authors: Schumacher A, Denecke B, Braunschweig T, Stahlschmidt J, Ziegler S, Brandenburg L, Stope M, Martincuks A, Vogt M, Gortz D, Camporeale A, Poli V, Muller-Newen G, Brummendorf T, Ziegler P
    J Hematol Oncol, 2015-06-09;8(0):64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  124. HoxA10 Terminates Emergency Granulopoiesis by Increasing Expression of Triad1.
    Authors: Wang H, Bei L, Shah C, Hu L, Eklund E
    J Immunol, 2015-04-20;194(11):5375-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Flow-induced protein kinase A-CREB pathway acts via BMP signaling to promote HSC emergence.
    Authors: Kim P, Nakano H, Das P, Chen M, Rowe R, Chou S, Ross S, Sakamoto K, Zon L, Schlaeger T, Orkin S, Nakano A, Daley G
    J Exp Med, 2015-04-13;212(5):633-48.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Hematopoietic stem/progenitor cells express several functional sex hormone receptors-novel evidence for a potential developmental link between hematopoiesis and primordial germ cells.
    Authors: Mierzejewska K, Borkowska S, Suszynska E, Suszynska M, Poniewierska-Baran A, Maj M, Pedziwiatr D, Adamiak M, Abdel-Latif A, Kakar S, Ratajczak J, Kucia M, Ratajczak M
    Stem Cells Dev, 2015-03-03;24(8):927-37.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  127. CD41 marks the initial myelo-erythroid lineage specification in adult mouse hematopoiesis: redefinition of murine common myeloid progenitor.
    Authors: Miyawaki K, Arinobu Y, Iwasaki H, Kohno K, Tsuzuki H, Iino T, Shima T, Kikushige Y, Takenaka K, Miyamoto T, Akashi K
    Stem Cells, 2015-03-01;33(3):976-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  128. The role of Lin28b in myeloid and mast cell differentiation and mast cell malignancy.
    Authors: Wang L, Rao T, Rowe R, Nguyen P, Sullivan J, Pearson D, Doulatov S, Wu L, Lindsley R, Zhu H, DeAngelo D, Daley G, Wagers A
    Leukemia, 2015-02-06;29(6):1320-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Grb10 is involved in BCR-ABL-positive leukemia in mice.
    Authors: Illert, A L, Albers, C, Kreutmair, S, Leischner, H, Peschel, C, Miething, C, Duyster, J
    Leukemia, 2014-09-24;29(4):858-68.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  130. A novel molecule Me6TREN promotes angiogenesis via enhancing endothelial progenitor cell mobilization and recruitment.
    Authors: Chen H, Wang S, Zhang J, Ren X, Zhang R, Shi W, Lv Y, Zhou Y, Yan X, Chen L, He L, Zhang B, Nan X, Yue W, Li Y, Pei X
    Sci Rep, 2014-08-28;4(0):6222.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Detecting protein-protein interactions based on kinase-mediated growth induction of mammalian cells.
    Authors: Mabe, Satoru, Nagamune, Teruyuki, Kawahara, Masahiro
    Sci Rep, 2014-08-19;4(0):6127.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Active enhancers are delineated de novo during hematopoiesis, with limited lineage fidelity among specified primary blood cells.
    Authors: Luyten A, Zang C, Liu X, Shivdasani R
    Genes Dev, 2014-08-15;28(16):1827-39.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  133. The DNA binding property of PML/RARA but not the integrity of PML nuclear bodies is indispensable for leukemic transformation.
    Authors: Liu X, Yuan H, Peres L, Chen S, Chen Z, de The H, Zhou J, Zhu J
    PLoS ONE, 2014-08-13;9(8):e104906.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  134. The effects of CAMPATH-1H on cell viability do not correlate to the CD52 density on the cell surface.
    Authors: Lee F, Luevano M, Veys P, Yong K, Madrigal A, Shaw B, Saudemont A
    PLoS ONE, 2014-07-22;9(7):e103254.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Endothelial cells translate pathogen signals into G-CSF-driven emergency granulopoiesis.
    Authors: Boettcher S, Gerosa R, Radpour R, Bauer J, Ampenberger F, Heikenwalder M, Kopf M, Manz M
    Blood, 2014-07-02;124(9):1393-403.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Embryonic stem cell-derived haematopoietic progenitor cells down-regulate the CD3 xi chain on T cells, abrogating alloreactive T cells.
    Authors: Kim E, Miyake B, Aggarwal M, Voetlause R, Griffith M, Zavazava N
    Immunology, 2014-07-01;142(3):421-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  137. TCR affinity and tolerance mechanisms converge to shape T cell diabetogenic potential.
    Authors: Bettini M, Blanchfield L, Castellaw A, Zhang Q, Nakayama M, Smeltzer M, Zhang H, Hogquist K, Evavold B, Vignali D
    J Immunol, 2014-06-18;193(2):571-9.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  138. Dynamic equilibrium of heterogeneous and interconvertible multipotent hematopoietic cell subsets.
    Authors: Weston W, Zayas J, Perez R, George J, Jurecic R
    Sci Rep, 2014-06-06;4(0):5199.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  139. Identification and characterization of circulating variants of CXCL12 from human plasma: effects on chemotaxis and mobilization of hematopoietic stem and progenitor cells.
    Authors: Richter R, Jochheim-Richter A, Ciuculescu F, Kollar K, Seifried E, Forssmann U, Verzijl D, Smit M, Blanchet X, von Hundelshausen P, Weber C, Forssmann W, Henschler R
    Stem Cells Dev, 2014-05-27;23(16):1959-74.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Targeting oncoprotein stability overcomes drug resistance caused by FLT3 kinase domain mutations.
    Authors: Yu, Chuanjia, Kancha, Rama Kri, Duyster, Justus
    PLoS ONE, 2014-05-21;9(5):e97116.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  141. Hes1 promotes blast crisis in chronic myelogenous leukemia through MMP-9 upregulation in leukemic cells.
    Authors: Nakahara F, Kitaura J, Uchida T, Nishida C, Togami K, Inoue D, Matsukawa T, Kagiyama Y, Enomoto Y, Kawabata K, Chen-Yi L, Komeno Y, Izawa K, Oki T, Nagae G, Harada Y, Harada H, Otsu M, Aburatani H, Heissig B, Hattori K, Kitamura T
    Blood, 2014-05-13;123(25):3932-42.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  142. The adult livers of immunodeficient mice support human hematopoiesis: evidence for a hepatic mast cell population that develops early in human ontogeny.
    Authors: Muench M, Beyer A, Fomin M, Thakker R, Mulvaney U, Nakamura M, Suemizu H, Barcena A
    PLoS ONE, 2014-05-12;9(5):e97312.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity.
    Authors: Nagareddy P, Kraakman M, Masters S, Stirzaker R, Gorman D, Grant R, Dragoljevic D, Hong E, Abdel-Latif A, Smyth S, Choi S, Korner J, Bornfeldt K, Fisher E, Dixit V, Tall A, Goldberg I, Murphy A
    Cell Metab, 2014-05-06;19(5):821-35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  144. CD41 is a reliable identification and activation marker for murine basophils in the steady state and during helminth and malarial infections.
    Authors: Bakocevic N, Claser C, Yoshikawa S, Jones L, Chew S, Goh C, Malleret B, Larbi A, Ginhoux F, de Lafaille M, Karasuyama H, Renia L, Ng L
    Eur J Immunol, 2014-04-10;44(6):1823-34.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  145. Establishment of a mast cell line, NCL-2, without Kit mutation, derived from NC mouse bone marrow.
    Authors: Hiragun T, Yanase Y, Okabe T, Hiragun M, Kawai M, Hide M
    FEBS Open Bio, 2014-04-02;4(0):342-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Sphingosine kinase 2 promotes acute lymphoblastic leukemia by enhancing MYC expression.
    Authors: Wallington-Beddoe C, Powell J, Tong D, Pitson S, Bradstock K, Bendall L
    Cancer Res, 2014-03-31;74(10):2803-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  147. Antineoplastic activity of rinvanil and phenylacetylrinvanil in leukaemia cell lines.
    Authors: Luviano A, Aguiniga-Sanchez I, Demare P, Tiburcio R, Ledesma-Martinez E, Santiago-Osorio E, Regla I
    Oncol Lett, 2014-03-10;7(5):1651-1656.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Mast cells contribute to bleomycin-induced lung inflammation and injury in mice through a chymase/mast cell protease 4-dependent mechanism.
    Authors: Reber L, Daubeuf F, Pejler G, Abrink M, Frossard N
    J Immunol, 2014-01-22;192(4):1847-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Expression of podocalyxin separates the hematopoietic and vascular potentials of mouse embryonic stem cell-derived mesoderm.
    Authors: Zhang H, Nieves J, Fraser S, Isern J, Douvaras P, Papatsenko D, D'Souza S, Lemischka I, Dyer M, Baron M
    Stem Cells, 2014-01-01;32(1):191-203.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  150. Prostaglandin E2-EP3 signaling induces inflammatory swelling by mast cell activation.
    Authors: Morimoto, Kazushi, Shirata, Naritosh, Taketomi, Yoshitak, Tsuchiya, Soken, Segi-Nishida, Eri, Inazumi, Tomoaki, Kabashima, Kenji, Tanaka, Satoshi, Murakami, Makoto, Narumiya, Shuh, Sugimoto, Yukihiko
    J Immunol, 2013-12-16;192(3):1130-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  151. Thymic stromal lymphopoietin-mediated extramedullary hematopoiesis promotes allergic inflammation.
    Authors: Siracusa M, Saenz S, Wojno E, Kim B, Osborne L, Ziegler C, Benitez A, Ruymann K, Farber D, Sleiman P, Hakonarson H, Cianferoni A, Wang M, Spergel J, Comeau M, Artis D
    Immunity, 2013-12-12;39(6):1158-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Gata2 cis-element is required for hematopoietic stem cell generation in the mammalian embryo.
    Authors: Gao, Xin, Johnson, Kirby D, Chang, Yuan-I, Boyer, Meghan E, Dewey, Colin N, Zhang, Jing, Bresnick, Emery H
    J Exp Med, 2013-12-02;210(13):2833-42.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  153. Identification of transcription factors for lineage-specific ESC differentiation.
    Authors: Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, Schlessinger D, Ko M
    Stem Cell Reports, 2013-11-27;1(6):545-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Oncogenic and drug-sensitive NTRK1 rearrangements in lung cancer.
    Authors: Vaishnavi A, Capelletti M, Le A, Kako S, Butaney M, Ercan D, Mahale S, Davies K, Aisner D, Pilling A, Berge E, Kim J, Sasaki H, Park S, Kryukov G, Garraway L, Hammerman P, Haas J, Andrews S, Lipson D, Stephens P, Miller V, Varella-Garcia M, Janne P, Doebele R
    Nat Med, 2013-10-27;19(11):1469-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  155. The leukemia-associated Mll-Ell oncoprotein induces fibroblast growth factor 2 (Fgf2)-dependent cytokine hypersensitivity in myeloid progenitor cells.
    Authors: Shah, Chirag A, Bei, Ling, Wang, Hao, Platanias, Leonidas, Eklund, Elizabet
    J Biol Chem, 2013-10-02;288(45):32490-505.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Induction of a hemogenic program in mouse fibroblasts.
    Authors: Pereira C, Chang B, Qiu J, Niu X, Papatsenko D, Hendry C, Clark N, Nomura-Kitabayashi A, Kovacic J, Ma'ayan A, Schaniel C, Lemischka I, Moore K
    Cell Stem Cell, 2013-06-13;13(2):205-18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Fas-associated phosphatase 1 (Fap1) influences betacatenin activity in myeloid progenitor cells expressing the Bcr-abl oncogene.
    Authors: Huang W, Bei L, Eklund E
    J Biol Chem, 2013-03-21;288(18):12766-76.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  158. IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation.
    Authors: Sandig H, Jobbings C, Roldan N, Whittingham-Dowd J, Orinska Z, Takeuchi O, Akira S, Bulfone-Paus S
    Eur J Immunol, 2013-03-06;43(4):979-88.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Establishment of a cell-type-specific genetic network by the mediator complex component Med1.
    Authors: Pope, Nathanie, Bresnick, Emery H
    Mol Cell Biol, 2013-03-04;33(10):1938-55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  160. HDL and Glut1 inhibition reverse a hypermetabolic state in mouse models of myeloproliferative disorders.
    Authors: Gautier E, Westerterp M, Bhagwat N, Cremers S, Shih A, Abdel-Wahab O, Lutjohann D, Randolph G, Levine R, Tall A, Yvan-Charvet L
    J Exp Med, 2013-01-14;210(2):339-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  161. The critical role of mast cell-derived hypoxia-inducible factor-1alpha in human and mice melanoma growth.
    Authors: Jeong H, Oh H, Nam S, Han N, Kim Y, Kim J, Lee S, Kim M, Moon P, Kim H, Oh H
    Int J Cancer, 2012-12-03;132(11):2492-501.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Regulation of innate CD8+ T-cell activation mediated by cytokines.
    Proc Natl Acad Sci U S A, 2012-06-04;109(25):9971-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  163. Differential but competitive binding of Nogo protein and class i major histocompatibility complex (MHCI) to the PIR-B ectodomain provides an inhibition of cells.
    Authors: Matsushita H, Endo S, Kobayashi E, Sakamoto Y, Kobayashi K, Kitaguchi K, Kuroki K, Soderhall A, Maenaka K, Nakamura A, Strittmatter SM, Takai T
    J. Biol. Chem., 2011-06-02;286(29):25739-47.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Neurexophilin 1 suppresses the proliferation of hematopoietic progenitor cells.
    Authors: Kinzfogl J, Hangoc G, Broxmeyer HE
    Blood, 2011-05-31;118(3):565-75.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  165. Interleukin-1 family cytokines as mucosal vaccine adjuvants for induction of protective immunity against influenza virus.
    Authors: Kayamuro H, Yoshioka Y, Abe Y, Arita S, Katayama K, Nomura T, Yoshikawa T, Kubota-Koketsu R, Ikuta K, Okamoto S, Mori Y, Kunisawa J, Kiyono H, Itoh N, Nagano K, Kamada H, Tsutsumi Y, Tsunoda S
    J. Virol., 2010-09-29;84(24):12703-12.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  166. Cyclin D1 regulates p27(Kip1) stability in B cells.
    Authors: Bustany S, Tchakarska G, Sola B
    Cell. Signal., 2010-09-15;23(1):171-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  167. MHC class II-dependent basophil-CD4+ T cell interactions promote T(H)2 cytokine-dependent immunity.
    Authors: Perrigoue JG, Saenz SA, Siracusa MC, Allenspach EJ, Taylor BC, Giacomin PR, Nair MG, Du Y, Zaph C, Van Rooijen N, Comeau MR, Pearce EJ, Laufer TM, Artis D
    Nat. Immunol., 2009-05-24;10(7):697-705.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Insertional gene activation by lentiviral and gammaretroviral vectors.
    Authors: Bokhoven M, Stephen SL, Knight S, Gevers EF, Robinson IC, Takeuchi Y, Collins MK
    J. Virol., 2008-10-22;83(1):283-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  169. IL-17B and IL-17C are associated with TNF-alpha production and contribute to the exacerbation of inflammatory arthritis.
    Authors: Yamaguchi Y, Fujio K, Shoda H, Okamoto A, Tsuno NH, Takahashi K, Yamamoto K
    J. Immunol., 2007-11-15;179(10):7128-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Osteoblasts support B-lymphocyte commitment and differentiation from hematopoietic stem cells.
    Authors: Zhu J, Garrett R, Jung Y, Zhang Y, Kim N, Wang J, Joe GJ, Hexner E, Choi Y, Taichman RS, Emerson SG
    Blood, 2007-01-16;109(9):3706-12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Rac1 and a GTPase-activating protein, MgcRacGAP, are required for nuclear translocation of STAT transcription factors.
    Authors: Bao YC, Nomura Y, Moon Y, Tonozuka Y, Minoshima Y, Hatori T, Tsuchiya A, Kiyono M, Nosaka T, Nakajima H
    J. Cell Biol., 2006-12-18;175(6):937-46.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Commonly dysregulated genes in murine APL cells.
    Authors: Yuan W, Payton JE, Holt MS, Link DC, Watson MA, DiPersio JF, Ley TJ
    Blood, 2006-09-28;109(3):961-70.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  173. SLAM family markers are conserved among hematopoietic stem cells from old and reconstituted mice and markedly increase their purity.
    Authors: Yilmaz OH, Kiel MJ, Morrison SJ
    Blood, 2005-10-11;107(3):924-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  174. Differential roles of vascular endothelial growth factor receptors 1 and 2 in dendritic cell differentiation.
    Authors: Dikov MM, Ohm JE, Ray N, Tchekneva EE, Burlison J, Moghanaki D, Nadaf S, Carbone DP
    J. Immunol., 2005-01-01;174(1):215-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  175. Enhanced circulating half-life and hematopoietic properties of a human granulocyte colony-stimulating factor/immunoglobulin fusion protein.
    Authors: Cox GN, Smith DJ, Carlson SJ, Bendele AM, Chlipala EA, Doherty DH
    Exp. Hematol., 2004-05-01;32(5):441-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  176. Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.
    Authors: Armstrong SA, Kung AL, Mabon ME, Silverman LB, Stam RW, Den Boer ML, Pieters R, Kersey JH, Sallan SE, Fletcher JA, Golub TR, Griffin JD, Korsmeyer SJ
    Cancer Cell, 2003-02-01;3(2):173-83.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  177. The IL-6 family cytokines, interleukin-6, interleukin-11, oncostatin M, and leukemia inhibitory factor, enhance mast cell growth through fibroblast-dependent pathway in mice.
    Authors: Gyotoku E, Morita E, Kameyoshi Y, Hiragun T, Yamamoto S, Hide M
    Arch. Dermatol. Res., 2001-11-01;293(10):508-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation.
    Authors: Liu F, Poursine-Laurent J, Wu HY, Link DC
    Blood, 1997-10-01;90(7):2583-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. Is there a mass to unit conversion for Recombinant Mouse IL-3 Protein (Catalog # 403-ML & 403-ML/CF)?

    • We have developed an approximate mass to unit conversion factor for Recombinant Mouse IL-3 Protein (Catalog # 403-ML & 403-ML/CF) based on testing against WHO Standard (NIBSC code: 91/662). In this testing, we found a relative conversion of 1 ug of cytokine = 1.7 x 105 Units. This information can be found in our Unit Conversion Table: https://www.rndsystems.com/resources/technical-information/unit-conversion-table

      Please note this information is for reference purposes only and is not routinely tested.

View all Proteins and Enzyme FAQs

Reviews for Recombinant Mouse IL-3 Protein

Average Rating: 4.3 (Based on 6 Reviews)

5 Star
33.33%
4 Star
66.67%
3 Star
0%
2 Star
0%
1 Star
0%

Have you used Recombinant Mouse IL-3 Protein?

Submit a review and receive an Amazon gift card.

$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image

$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image

Submit a Review

Filter by:


Recombinant Mouse IL-3 Protein
By Anonymous on 11/20/2021
Application: In vitro bioactivity in cell culture
Recombinant Mouse IL-3 Protein
By Anonymous on 06/15/2018
Application: Immunoassay Standard
Recombinant Mouse IL-3 Protein
By Anonymous on 05/14/2018
Application: Cell Adhesion
Recombinant Mouse IL-3 Protein
By Anonymous on 04/26/2017

I used IL-3 to culture my Ba/F3 cells. With IL3, they are growing well and viable.

Recombinant Mouse IL-3 Protein
By Marco Ramos on 04/04/2017
Application: CellProlif
Reason for Rating: Expensive but worth the money
Recombinant Mouse IL-3 Protein
By Anonymous on 05/18/2016
Application: Cell migration/motility