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Recombinant Mouse HGF Protein

Catalog #: 2207-HG
59 Citations Datasheet / COA / SDS

Carrier Free

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2207-HG-025/CF

With Carrier

Catalog # Availability Size / Price Qty
2207-HG-025
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Citations (59)
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Recombinant Mouse HGF Protein Summary

Product Specifications

Purity
>95%, by SDS-PAGE under reducing conditions and visualized by silver stain
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using mIMCD‑3 mouse epithelial cells. The ED50 for this effect is 10-30 ng/mL. Measured by its ability to bind Recombinant Mouse HGF R/c-MET Fc Chimera (Catalog # 7065-ME) in a functional ELISA with an estimated KD <0.2 nM.
Source
Mouse myeloma cell line, NS0-derived mouse HGF protein
Gln33-Arg495 (alpha) & Val496-Leu728 (beta)
Accession #
Q53WS5
N-terminal Sequence
Analysis
No results obtained: Gln33 predicted (alpha) & Val496 (beta)
Structure / Form
Disulfide-linked heterodimer
Predicted Molecular Mass
53.4 kDa ( alpha -chain), 26 kDa ( beta -chain)
SDS-PAGE
60 kDa and 33 kDa, reducing conditions

Product Datasheets

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2207-HG (with carrier)

Product Datasheet
COA
SDS

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2207-HG/CF (carrier free)

Product Datasheet
COA
SDS

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

2207-HG

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

2207-HG/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: HGF

HGF, also known as Scatter Factor and Hepatopoietin A, is a pleiotropic protein in the Plasminogen subfamily of S1 peptidases. It is a multidomain molecule that includes an N-terminal PAN/APPLE-like domain, four Kringle domains, and a serine proteinase-like domain that has no detectable protease activity (1 - 5). Mouse HGF is secreted as an inactive 728 amino acid (aa) single chain propeptide. It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha  and 30 kDa beta  chain. Alternate splicing generates an isoform that lacks the peptidase and the second, third, and fourth Kringle domains. Mouse HGF shares 91% - 95% aa sequence identity with bovine, canine, feline, human, and rat HGF. HGF binds heparan-sulfate proteoglycans and the widely expressed receptor tyrosine kinase, HGF R/c-MET (6, 7). HGF‑dependent c-MET activation is implicated in the development of many human cancers (8). HGF regulates epithelial morphogenesis by inducing cell scattering and branching tubulogenesis (9, 10). HGF induces the up‑regulation of integrin alpha 2 beta 1 in epithelial cells by a selective increase in alpha 2 gene transcription (11). This integrin serves as a collagen I receptor, and its blockade disrupts epithelial cell branching tubulogenesis (11, 12). HGF can also alter epithelium morphology by the induction of nectin‑1 alpha  ectodomain shedding, an adhesion protein component of adherens junctions (13). In the thyroid, HGF induces the proliferation, motility, and loss of differentiation markers of thyrocytes and inhibits TSH-stimulated iodine uptake (14). HGF promotes the motility of cardiac stem cells in damaged myocardium (15).

References
  1. Karihaloo, A. et al. (2005) Nephron Exp. Nephrol. 100:e40.
  2. Hammond, D.E. et al. (2004) Curr. Top. Microbiol. Immunol. 286:21.
  3. Rosario, M. and W. Birchmeier (2004) Dev. Cell 7:3.
  4. Lesk, A.M. and W.D. Fordham (1996) J. Mol. Biol. 258:501.
  5. Sasaki, M. et al. (1994) Biochem. Biophys. Res. Commun. 199:772.
  6. Mizuno, K., et al. (1994) J. Biol. Chem. 269:1131.
  7. Gheradi, E. et al. (2003) Proc. Natl. Acad. Sci. 100:12039.
  8. Corso, S. et al. (2005) Trends Mol. Med. 11:284.
  9. Maeshima, A. et al. (2000) Kid. Int. 58:1511.
  10. Montesano, R. et al. (1991) Cell 67:901.
  11. Chiu, S-J. et al. (2002) J. Biomed. Sci. 9:261.
  12. Saelman, E.U.M. et al. (1995) J. Cell Sci. 108:3531.
  13. Tanaka, Y. et al. (2002) Biochem. Biophys. Res. Commun. 299:472.
  14. Mineo, R. et al. (1994) Endocrinology 145:4355.
  15. Urbanek, K. et al. (2005) Circ. Res. 97:663.
Long Name
Hepatocyte Growth Factor
Entrez Gene IDs
3082 (Human); 15234 (Mouse); 24446 (Rat); 403441 (Canine); 102133907 (Cynomolgus Monkey); 493705 (Feline)
Alternate Names
deafness, autosomal recessive 39; DFNB39; EC 3.4.21; EC 3.4.21.7; fibroblast-derived tumor cytotoxic factor; F-TCF; hepatocyte growth factor (hepapoietin A; scatter factor); Hepatopoeitin-A; Hepatopoietin A; HGF; HGFB; HPTA; HPTAhepatocyte growth factor; lung fibroblast-derived mitogen; Scatter factor; SF; SFhepatopoeitin-A

Citations for Recombinant Mouse HGF Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

59 Citations: Showing 1 - 10
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  1. SOX9-positive pituitary stem cells differ according to their position in the gland and maintenance of their progeny depends on context
    Authors: Rizzoti, K;Chakravarty, P;Sheridan, D;Lovell-Badge, R;
    Science advances
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Deletion of Cd44 Inhibits Metastasis Formation of Liver Cancer in Nf2-Mutant Mice
    Authors: Gerardo-Ram�rez, M;Giam, V;Becker, D;Groth, M;Hartmann, N;Morrison, H;May-Simera, HL;Radsak, MP;Marquardt, JU;Galle, PR;Herrlich, P;Straub, BK;Hartmann, M;
    Cells
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  3. IL-6-GP130 signaling protects human hepatocytes against lipid droplet accumulation in humanized liver models
    Authors: M Carbonaro, K Wang, H Huang, D Frleta, A Patel, A Pennington, M Desclaux, S Moller-Tan, J Grindley, J Altarejos, J Zhong, G Polites, W Poueymirou, S Jaspers, C Kyratsous, B Zambrowicz, A Murphy, JC Lin, LE Macdonald, C Daly, M Sleeman, G Thurston, Z Li
    Science Advances, 2023-04-14;9(15):eadf4490.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Bioassay
  4. Simple Detection and Culture of Circulating Tumor Cells from Colorectal Cancer Patients Using Poly(2-Methoxyethyl Acrylate)-Coated Plates
    Authors: M Nomura, Y Yokoyama, D Yoshimura, Y Minagawa, A Yamamoto, Y Tanaka, N Sekiguchi, D Marukawa, M Ichihara, H Itakura, K Matsumoto, Y Morimoto, H Tomihara, A Inoue, T Ogino, N Miyoshi, H Takahashi, H Takahashi, M Uemura, S Kobayashi, T Mizushima, T Anada, M Mori, Y Doki, M Tanaka, H Eguchi, H Yamamoto
    International Journal of Molecular Sciences, 2023-02-16;24(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Opposing roles of hepatic stellate cell subpopulations in hepatocarcinogenesis
    Authors: A Filliol, Y Saito, A Nair, DH Dapito, LX Yu, A Ravichandr, S Bhattachar, S Affo, N Fujiwara, H Su, Q Sun, TM Savage, JR Wilson-Kan, JM Caviglia, L Chin, D Chen, X Wang, S Caruso, JK Kang, AD Amin, S Wallace, R Dobie, D Yin, OM Rodriguez-, C Yin, A Mehal, B Izar, RA Friedman, RG Wells, UB Pajvani, Y Hoshida, HE Remotti, N Arpaia, J Zucman-Ros, M Karin, NC Henderson, I Tabas, RF Schwabe
    Nature, 2022-10-05;0(0):.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Loss of full-length dystrophin expression results in major cell-autonomous abnormalities in proliferating myoblasts
    Authors: MRF Gosselin, V Mournetas, M Borczyk, S Verma, A Occhipinti, J Róg, L Bozycki, M Korostynsk, SC Robson, C Angione, C Pinset, DC Gorecki
    Elife, 2022-09-27;11(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  7. A pilot study on nitration/dysfunction of NK1 segment of myogenic stem cell activator HGF
    Authors: A Elgaabari, N Imatomi, H Kido, M Seki, S Tanaka, Y Matsuyoshi, T Nakashima, S Sawano, W Mizunoya, T Suzuki, M Nakamura, JE Anderson, R Tatsumi
    Biochemistry and Biophysics Reports, 2022-06-11;31(0):101295.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Loss of Tpl2 activates compensatory signaling and resistance to EGFR/MET dual inhibition in v-RAS transduced keratinocytes
    Authors: MB Kelley, TJ Geddes, M Ochiai, NM Lampl, WW Kothmann, SR Fierstein, V Kent, K DeCicco-Sk
    PLoS ONE, 2022-03-24;17(3):e0266017.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  9. Transplantation of intestinal organoids into a mouse model of colitis
    Authors: S Watanabe, S Kobayashi, N Ogasawara, R Okamoto, T Nakamura, M Watanabe, KB Jensen, S Yui
    Nature Protocols, 2022-02-02;0(0):.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  10. Growth Factors Do Not Improve Muscle Function in Young or Adult mdx Mice
    Authors: TL Nielsen, TM Hornsyld, T Pinós, C Brolin, J Vissing, TO Krag
    Biomedicines, 2022-01-28;10(2):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  11. BMP9 Promotes an Epithelial Phenotype and a Hepatocyte-like Gene Expression Profile in Adult Hepatic Progenitor Cells
    Authors: A Addante, C González-C, C Roncero, N Lazcanoitu, J García-Sáe, B Herrera, A Sánchez
    Cells, 2022-01-21;11(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Suppression of lipopolysaccharide-induced corneal opacity by hepatocyte growth factor
    Authors: E Elbasiony, W Cho, SK Mittal, SK Chauhan
    Scientific Reports, 2022-01-11;12(1):494.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  13. ADAM10 and ADAM17 regulate EGFR, c-Met and TNF RI signalling in liver regeneration and fibrosis
    Authors: O Zbodakova, K Chalupsky, L Sarnova, P Kasparek, M Jirouskova, M Gregor, R Sedlacek
    Scientific Reports, 2021-06-01;11(1):11414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  14. TFEB regulates murine liver cell fate during development and regeneration
    Authors: N Pastore, T Huynh, NJ Herz, A Calcagni', TJ Klisch, L Brunetti, KH Kim, M De Giorgi, A Hurley, A Carissimo, M Mutarelli, N Aleksieva, L D'Orsi, WR Lagor, DD Moore, C Settembre, MJ Finegold, SJ Forbes, A Ballabio
    Nat Commun, 2020-05-18;11(1):2461.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  15. Hepatocyte growth factor protects PC12 cells against OGD/R-induced injury by reducing iron
    Authors: S Li, ZM Qian, G Xu, J Zheng, Y Wu
    Biosci. Rep., 2020-04-30;40(4):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Culture
  16. A Signaling Crosstalk between BMP9 and HGF/c-Met Regulates Mouse Adult Liver Progenitor Cell Survival
    Authors: A Addante, C Roncero, N Lazcanoitu, R Méndez, L Almalé, M García-Álv, P Ten Dijke, I Fabregat, B Herrera, A Sánchez
    Cells, 2020-03-19;9(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  17. Mutant IDH1 confers resistance to energy stress in normal biliary cells through PFKP-induced aerobic glycolysis and AMPK activation
    Authors: H Fujiwara, K Tateishi, K Misumi, A Hayashi, K Igarashi, H Kato, T Nakatsuka, N Suzuki, K Yamamoto, Y Kudo, Y Hayakawa, H Nakagawa, Y Tanaka, H Ijichi, H Kogure, Y Nakai, H Isayama, K Hasegawa, M Fukayama, T Soga, K Koike
    Sci Rep, 2019-12-11;9(1):18859.
    Species: Mouse
    Sample Types: Organoid
    Applications: Bioassay
  18. Mesenchymal stem cells induce dendritic cell immune tolerance via paracrine hepatocyte growth factor to alleviate acute lung injury
    Authors: Z Lu, W Chang, S Meng, X Xu, J Xie, F Guo, Y Yang, H Qiu, L Liu
    Stem Cell Res Ther, 2019-12-04;10(1):372.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  19. p53 controls the plasticity of mammary luminal progenitor cells downstream of Met signaling
    Authors: A Chiche, A Di-Cicco, L Sesma-Sanz, L Bresson, P de la Gran, MA Glukhova, MM Faraldo, MA Deugnier
    Breast Cancer Res., 2019-01-25;21(1):13.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Inhibition of HGF/MET signaling decreases overall tumor burden and blocks malignant conversion in Tpl2-related skin cancer
    Authors: NF Bonan, D Kowalski, K Kudlac, K Flaherty, JC Gwilliam, LG Falkenberg, E Maradiaga, KL DeCicco-Sk
    Oncogenesis, 2019-01-10;8(1):1.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Hepatocyte Growth Factor alleviates hepatic insulin resistance and lipid accumulation in high-fat diet-fed mice
    Authors: Y Jing, Q Sun, X Xiong, R Meng, S Tang, S Cao, Y Bi, D Zhu
    J Diabetes Investig, 2018-09-14;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  22. Characterization of induced tissue-specific stem cells from pancreas by a synthetic self-replicative RNA
    Authors: C Miyagi-Shi, Y Nakashima, N Kobayashi, I Saitoh, M Watanabe, H Noguchi
    Sci Rep, 2018-08-17;8(1):12341.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. IL-17A-Induced PLET1 Expression Contributes to Tissue Repair and Colon Tumorigenesis
    Authors: JA Zepp, J Zhao, C Liu, K Bulek, L Wu, X Chen, Y Hao, Z Wang, X Wang, W Ouyang, MF Kalady, J Carman, WP Yang, J Zhu, C Blackburn, YH Huang, TA Hamilton, B Su, X Li
    J. Immunol., 2017-10-25;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. Semaphorin 4C Plexin-B2 signaling in peripheral sensory neurons is pronociceptive in a model of inflammatory pain
    Authors: E Paldy, M Simonetti, T Worzfeld, KK Bali, L Vicuña, S Offermanns, R Kuner
    Nat Commun, 2017-08-02;8(1):176.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  25. Transcription factor Etv5 is essential for the maintenance of alveolar type II cells
    Authors: Z Zhang, K Newton, SK Kummerfeld, J Webster, DS Kirkpatric, L Phu, J Eastham-An, J Liu, WP Lee, J Wu, H Li, MR Junttila, VM Dixit
    Proc. Natl. Acad. Sci. U.S.A, 2017-03-28;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Bioassay
  26. BMP-9 interferes with liver regeneration and promotes liver fibrosis
    Authors: K Breitkopf-, C Meyer, C König, H Gaitantzi, A Addante, M Thomas, E Wiercinska, C Cai, Q Li, F Wan, C Hellerbran, NA Valous, M Hahnel, C Ehlting, JG Bode, S Müller-Boh, U Klingmülle, J Altenöder, I Ilkavets, MJ Goumans, LJ Hawinkels, SJ Lee, M Wieland, C Mogler, MP Ebert, B Herrera, H Augustin, A Sánchez, S Dooley, P Ten Dijke
    Gut, 2017-03-23;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  27. JMJD3 aids in reprogramming of bone marrow progenitor cells to hepatic phenotype through epigenetic activation of hepatic transcription factors
    Authors: V Kochat, Z Equbal, P Baligar, V Kumar, M Srivastava, A Mukhopadhy
    PLoS ONE, 2017-03-22;12(3):e0173977.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Generation of non-viral, transgene-free hepatocyte like cells with piggyBac transposon
    Authors: H Katayama, K Yasuchika, Y Miyauchi, H Kojima, R Yamaoka, T Kawai, E Yukie Yosh, S Ogiso, S Kita, K Yasuda, N Sasaki, K Fukumitsu, J Komori, T Ishii, S Uemoto
    Sci Rep, 2017-03-15;7(0):44498.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Pigment epithelium-derived factor (PEDF) peptide promotes the expansion of hepatic stem/progenitor cells via ERK and STAT3-dependent signaling
    Authors: SC Shih, TC Ho, SL Chen, YP Tsao
    Am J Transl Res, 2017-03-15;9(3):1114-1126.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Novel combinatorial screening identifies neurotrophic factors for selective classes of motor neurons
    Authors: S Schaller, D Buttigieg, A Alory, A Jacquier, M Barad, M Merchant, D Gentien, P de la Gran, G Haase
    Proc. Natl. Acad. Sci. U.S.A, 2017-03-07;114(12):E2486-E2493.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. NG2 glial cells regulate neuroimmunological responses to maintain neuronal function and survival
    Authors: M Nakano, Y Tamura, M Yamato, S Kume, A Eguchi, K Takata, Y Watanabe, Y Kataoka
    Sci Rep, 2017-02-14;7(0):42041.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  32. Progressive induction of hepatocyte progenitor cells in chronically injured liver
    Authors: N Tanimizu, N Ichinohe, M Yamamoto, H Akiyama, Y Nishikawa, T Mitaka
    Sci Rep, 2017-01-04;7(0):39990.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Data supporting regulating temporospatial dynamics of morphogen for structure formation of the lacrimal gland by chitosan biomaterials
    Data Brief, 2016-11-19;10(0):108-115.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Ex Vivo
  34. Restoration of Corneal Transparency by Mesenchymal Stem Cells.
    Authors: Sharad K Mittal, Masahiro Omoto, Afsaneh Amouzegar, Anuradha Sahu, Alexandra Rezazadeh, Kishore R Katikired, Dhvanit I Shah, Srikant K Sahu, Sunil K Chauhan
    Stem Cell Reports, 2016-09-29;0(0):2213-6711.
    Species: Mouse
    Sample Types: In Vivo, Transfected Whole Cells, Whole Cells
    Applications: Bioassay, In Vivo
  35. Retinol Promotes In Vitro Growth of Proximal Colon Organoids through a Retinoic Acid-Independent Mechanism
    PLoS ONE, 2016-08-26;11(8):e0162049.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  36. Influenza Virus Infects Epithelial Stem/Progenitor Cells of the Distal Lung: Impact on Fgfr2b-Driven Epithelial Repair
    Authors: Jennifer Quantius
    PLoS Pathog, 2016-06-20;12(6):e1005544.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Image-based detection and targeting of therapy resistance in pancreatic adenocarcinoma
    Authors: Raymond G Fox
    Nature, 2016-06-06;534(7607):407-11.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  38. Necrotic cell-derived high mobility group box 1 attracts antigen-presenting cells but inhibits hepatocyte growth factor-mediated tropism of mesenchymal stem cells for apoptotic cell death.
    Authors: Vogel S, Borger V, Peters C, Forster M, Liebfried P, Metzger K, Meisel R, Daubener W, Trapp T, Fischer J, Gawaz M, Sorg R
    Cell Death Differ, 2015-01-09;22(7):1219-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Identification and characterization of mesenchymal-epithelial progenitor-like cells in normal and injured rat liver.
    Authors: Liu D, Yovchev M, Zhang J, Alfieri A, Tchaikovskaya T, Laconi E, Dabeva M
    Am J Pathol, 2014-11-06;185(1):110-28.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Cell-based therapy for acute and chronic liver failures: distinct diseases, different choices.
    Authors: Sun K, Xie X, Xie J, Jiao S, Chen X, Zhao X, Wang X, Wei L
    Sci Rep, 2014-09-29;4(0):6494.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Induction of tissue-specific stem cells by reprogramming factors, and tissue-specific selection.
    Authors: Noguchi, H, Saitoh, I, Tsugata, T, Kataoka, H, Watanabe, M, Noguchi, Y
    Cell Death Differ, 2014-09-05;22(1):145-55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Unfolded protein response is required for the definitive endodermal specification of mouse embryonic stem cells via Smad2 and beta-catenin signaling.
    Authors: Xu H, Tsang K, Wang Y, Chan J, Xu G, Gao W
    J Biol Chem, 2014-08-04;289(38):26290-301.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Mutant IDH inhibits HNF-4alpha to block hepatocyte differentiation and promote biliary cancer.
    Authors: Saha S, Parachoniak C, Ghanta K, Fitamant J, Ross K, Najem M, Gurumurthy S, Akbay E, Sia D, Cornella H, Miltiadous O, Walesky C, Deshpande V, Zhu A, Hezel A, Yen K, Straley K, Travins J, Popovici-Muller J, Gliser C, Ferrone C, Apte U, Llovet J, Wong K, Ramaswamy S, Bardeesy N
    Nature, 2014-07-02;513(7516):110-4.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. Muscle atrophy reversed by growth factor activation of satellite cells in a mouse muscle atrophy model.
    Authors: Hauerslev, Simon, Vissing, John, Krag, Thomas O
    PLoS ONE, 2014-06-25;9(6):e100594.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  45. Intra-myocardial injection of both growth factors and heart derived Sca-1+/CD31- cells attenuates post-MI LV remodeling more than does cell transplantation alone: neither intervention enhances functionally significant cardiomyocyte regeneration.
    Authors: Wang X, Li Q, Hu Q, Suntharalingam P, From A, Zhang J
    PLoS ONE, 2014-06-11;9(2):e95247.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Involvement of hepatic stimulator substance in the regulation of hepatoblast maturation into hepatocytes in vitro.
    Authors: Sun G, Dong L, An W
    Stem Cells Dev, 2014-05-02;23(14):1675-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. HGF signaling impacts severity of Pseudomonas aeruginosa keratitis.
    Authors: Jiang X, McClellan S, Barrett R, Foldenauer M, Hazlett L
    Invest Ophthalmol Vis Sci, 2014-04-09;55(4):2180-90.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  48. Glypican-1 regulates myoblast response to HGF via Met in a lipid raft-dependent mechanism: effect on migration of skeletal muscle precursor cells.
    Authors: Gutierrez J, Cabrera D, Brandan E
    Skelet Muscle, 2014-02-12;4(1):5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Identification of transcription factors for lineage-specific ESC differentiation.
    Authors: Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, Schlessinger D, Ko M
    Stem Cell Reports, 2013-11-27;1(6):545-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Multipotent human mesenchymal stromal cells mediate expansion of myeloid-derived suppressor cells via hepatocyte growth factor/c-met and STAT3.
    Authors: Yen B, Yen M, Hsu P, Liu K, Wang C, Bai C, Sytwu H
    Stem Cell Reports, 2013-07-25;1(2):139-51.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  51. Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors.
    Authors: Hunter, K E, Palermo, C, Kester, J C, Simpson, K, Li, J-P, Tang, L H, Klimstra, D S, Vlodavsky, I, Joyce, J A
    Oncogene, 2013-05-06;33(14):1799-808.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Factors expressed by murine embryonic pancreatic mesenchyme enhance generation of insulin-producing cells from hESCs.
    Authors: Guo T, Landsman L, Li N, Hebrok M
    Diabetes, 2013-01-10;62(5):1581-92.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  53. The restorative effects of adipose-derived mesenchymal stem cells on damaged ovarian function.
    Authors: Takehara, Yuji, Yabuuchi, Akiko, Ezoe, Kenji, Kuroda, Tomoko, Yamadera, Rie, Sano, Chiaki, Murata, Nana, Aida, Takuya, Nakama, Ken, Aono, Fumihito, Aoyama, Naoki, Kato, Keiich, Kato, Osamu
    Lab Invest, 2012-11-19;93(2):181-93.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Bioassay
  54. Self-renewal of embryonic-stem-cell-derived progenitors by organ-matched mesenchyme.
    Authors: Sneddon, Julie B, Borowiak, Malgorza, Melton, Douglas
    Nature, 2012-10-07;491(7426):765-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  55. c-Met and its ligand hepatocyte growth factor/scatter factor regulate mature B cell survival in a pathway induced by CD74.
    Authors: Gordin M, Tesio M, Cohen S
    J. Immunol., 2010-07-16;185(4):2020-31.
    Species: Mouse
    Sample Types: In Vivo, Whole Cells
    Applications: Bioassay, In Vivo
  56. Enhanced c-Met activity promotes G-CSF-induced mobilization of hematopoietic progenitor cells via ROS signaling.
    Authors: Tesio M, Golan K, Corso S
    Blood, 2010-06-28;117(2):419-28.
    Species: Mouse
    Sample Types: In Vivo, N/A
    Applications: ELISA (Standard), In Vivo
  57. MCP-1 antibody treatment enhances damage and impedes repair of the alveolar epithelium in influenza pneumonitis.
    Authors: Narasaraju T, Ng HH, Phoon MC
    Am. J. Respir. Cell Mol. Biol., 2009-07-17;42(6):732-43.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  58. Possible implication of satellite cells in regenerative motoneuritogenesis: HGF upregulates neural chemorepellent Sema3A during myogenic differentiation.
    Authors: Tatsumi R, Sankoda Y, Anderson JE, Sato Y, Mizunoya W, Shimizu N, Suzuki T, Yamada M, Rhoads RP, Ikeuchi Y, Allen RE
    Am. J. Physiol., Cell Physiol., 2009-06-10;297(2):C238-52.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. Hepatocyte growth factor is a lymphangiogenic factor with an indirect mechanism of action.
    Authors: Cao R, Bjorndahl MA, Gallego MI, Chen S, Religa P, Hansen AJ, Cao Y
    Blood, 2006-01-19;107(9):3531-6.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo

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