Recombinant Human IgG1 Fc Protein, CF

Granulocyte-Macrophage Colony-Stimulating Factor (GM-CSF) Influence on Soluble and Membrane Bound ICOS in Combination with Immune Checkpoint Blockade
Authors: Li, X;Li, J;Zheng, Y;Lee, SJ;Zhou, J;Giobbie-Hurder, A;Butterfield, LH;Dranoff, G;Hodi, FS;
Cancer immunology research
Species: Human
Sample Types: Whole Cells
Applications: Neutralization Control

Semaphorin 4D induced inhibitory synaptogenesis decreases epileptiform activity and alters progression to Status Epilepticus in mice
Authors: Adel, SS;Clarke, VRJ;Evans-Strong, A;Maguire, J;Paradis, S;
Epilepsy research
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

AXL-Receptor Targeted 14FN3 Based Single Domain Proteins (Pronectins�) from 3 Synthetic Human Libraries as Components for Exploring Novel Bispecific Constructs against Solid Tumors
Authors: CA Hokanson, E Zacco, G Cappuccill, T Odineca, R Crea
Biomedicines, 2022-12-08;10(12):.
Species: Mouse
Sample Types: Whole Cell
Applications: Bioassay

Identification of TFPI as a receptor reveals recombination-driven receptor switching in Clostridioides difficile toxin B variants
Authors: S Tian, X Xiong, J Zeng, S Wang, BJ Tremblay, P Chen, B Chen, M Liu, P Chen, K Sheng, D Zeve, W Qi, DT Breault, C Rodríguez, R Gerhard, R Jin, AC Doxey, M Dong
Nature Communications, 2022-11-09;13(1):6786.
Species: Human
Sample Types: Protein
Applications: Reference Standard

Altered Circulating Follicular T Helper Cell Subsets and Follicular T Regulatory Cells Are Indicators of a Derailed B Cell Response in Lupus, Which Could Be Modified by Targeting IL-21R
Authors: K Szabó, I Jámbor, K Pázmándi, N Nagy, G Papp, T Tarr
International Journal of Molecular Sciences, 2022-10-13;23(20):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

NKp44-based chimeric antigen receptor effectively redirects primary T cells against synovial sarcoma
Authors: Y Murayama, Y Kasahara, N Kubo, C Shin, M Imamura, N Oike, T Ariizumi, A Saitoh, M Baba, T Miyazaki, Y Suzuki, Y Ling, S Okuda, K Mihara, A Ogose, H Kawashima, C Imai
Translational Oncology, 2022-08-20;25(0):101521.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry

Distinct antibody clones detect PD-1 checkpoint expression and block PD-L1 interactions on live murine melanoma cells
Authors: C Martins, M Silva, E Rasbach, P Singh, Y Itoh, JB Williams, E Statham, A Meurer, DV Martinez, A Brandenbur, MV Heppt, SR Barthel, T Schatton
Scientific Reports, 2022-07-21;12(1):12491.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Neuropilin 1 and its inhibitory ligand mini-tryptophanyl-tRNA synthetase inversely regulate VE-cadherin turnover and vascular permeability
Authors: N Gioelli, LJ Neilson, N Wei, G Villari, W Chen, B Kuhle, M Ehling, F Maione, S Willox, S Brundu, D Avanzato, G Koulouras, M Mazzone, E Giraudo, XL Yang, D Valdembri, S Zanivan, G Serini
Nature Communications, 2022-07-20;13(1):4188.
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay

EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
Authors: SL Banerjee, F Lessard, FJM Chartier, K Jacquet, AI Osornio-He, V Teyssier, K Ghani, N Lavoie, JN Lavoie, M Caruso, P Laprise, S Elowe, JP Lambert, N Bisson
Cell Reports, 2022-07-05;40(1):111031.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

3D Visualization of Human Blood Vascular Networks Using Single-Domain Antibodies Directed against Endothelial Cell-Selective Adhesion Molecule (ESAM)
Authors: NR Hansmeier, IS Büschlen, RY Behncke, S Ulferts, R Bisoendial, R Hägerling
International Journal of Molecular Sciences, 2022-04-15;23(8):.
Species: N/A
Sample Types: Whole Cells
Applications: Bioassay

Ephrin receptor A10 monoclonal antibodies and the derived chimeric antigen receptor T cells exert an antitumor response in mouse models of triple-negative breast cancer
Authors: JH Cha, LC Chan, YN Wang, YY Chu, CH Wang, HH Lee, W Xia, WC Shyu, SP Liu, J Yao, CW Chang, FR Cheng, J Liu, SO Lim, JL Hsu, WH Yang, GN Hortobagyi, C Lin, L Yang, D Yu, LB Jeng, MC Hung
The Journal of Biological Chemistry, 2022-03-10;0(0):101817.
Species: N/A
Sample Types: Protein
Applications: ELISA Capture

RTN4/Nogo-A-S1PR2 negatively regulates angiogenesis and secondary neural repair through enhancing vascular autophagy in the thalamus after cerebral cortical infarction
Authors: P Xiao, J Gu, W Xu, X Niu, J Zhang, J Li, Y Chen, Z Pei, J Zeng, S Xing
Autophagy, 2022-03-09;0(0):1-20.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Tumor Cell-Autonomous Pro-Metastatic Activities of PD-L1 in Human Breast Cancer Are Mediated by PD-L1-S283 and Chemokine Axes
Authors: N Erlichman, T Baram, T Meshel, D Morein, B Da'adoosh, A Ben-Baruch
Cancers, 2022-02-18;14(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Targeting necroptosis in muscle fibers ameliorates inflammatory myopathies
Authors: M Kamiya, F Mizoguchi, K Kawahata, D Wang, M Nishibori, J Day, C Louis, IP Wicks, H Kohsaka, S Yasuda
Nature Communications, 2022-01-10;13(1):166.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Receptor Activator of NF-kappaB (RANK) Confers Resistance to Chemotherapy in AML and Associates with Dismal Disease Course
Authors: KL Clar, LM Weber, BJ Schmied, JS Heitmann, M Marconato, C Tandler, P Schneider, HR Salih
Cancers, 2021-12-04;13(23):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S1P Increases VEGF Production in Osteoblasts and Facilitates Endothelial Progenitor Cell Angiogenesis by Inhibiting miR-16-5p Expression via the c-Src/FAK Signaling Pathway in Rheumatoid Arthritis
Authors: CC Huang, TT Tseng, SC Liu, YY Lin, YY Law, SL Hu, SW Wang, CH Tsai, CH Tang
Cells, 2021-08-23;10(8):.
Species: Human
Sample Types: Reference Standard

A subthreshold synaptic mechanism regulating BDNF expression and resting synaptic strength
Authors: PM Horvath, NL Chanaday, B Alten, ET Kavalali, LM Monteggia
Cell Reports, 2021-08-03;36(5):109467.
Species: Rat
Sample Types: Whole Cells
Applications: Reference Standard

Computational design of a synthetic PD-1 agonist
Authors: CM Bryan, GJ Rocklin, MJ Bick, A Ford, S Majri-Morr, AV Kroll, CJ Miller, L Carter, I Goreshnik, A Kang, F DiMaio, KV Tarbell, D Baker
Proceedings of the National Academy of Sciences of the United States of America, 2021-07-20;118(29):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Inherited PD-1 deficiency underlies tuberculosis and autoimmunity in a child
Authors: M Ogishi, R Yang, C Aytekin, D Langlais, M Bourgey, T Khan, FA Ali, M Rahman, OM Delmonte, M Chrabieh, P Zhang, C Gruber, SJ Pelham, AN Spaan, J Rosain, WT Lei, S Drutman, MD Hellmann, MK Callahan, M Adamow, P Wong, JD Wolchok, G Rao, CS Ma, Y Nakajima, T Yaguchi, K Chamoto, SC Williams, JF Emile, F Rozenberg, MS Glickman, F Rapaport, G Kerner, G Allington, I Tezcan, D Cagdas, FO Hosnut, F Dogu, A Ikinciogul, VK Rao, L Kainulaine, V Béziat, J Bustamante, S Vilarinho, RP Lifton, B Boisson, L Abel, D Bogunovic, N Marr, LD Notarangel, SG Tangye, T Honjo, P Gros, S Boisson-Du, JL Casanova
Nature Medicine, 2021-06-28;0(0):.
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay

Novel human neutralizing mAbs specific for Spike-RBD of SARS-CoV-2
Authors: M Passariell, C Gentile, V Ferrucci, E Sasso, C Vetrei, G Fusco, M Viscardi, S Brandi, P Cerino, N Zambrano, M Zollo, C De Lorenzo
Scientific Reports, 2021-05-26;11(1):11046.
Species: Human
Sample Types: Virus
Applications: Affinity Purification

CD200-CD200R immune checkpoint engagement regulates ILC2 effector function and ameliorates lung inflammation in asthma
Authors: P Shafiei-Ja, DG Helou, BP Hurrell, E Howard, C Quach, JD Painter, L Galle-Treg, M Li, YE Loh, O Akbari
Nature Communications, 2021-05-05;12(1):2526.
Species: Human, Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

Aggressive and recurrent ovarian cancers upregulate ephrinA5, a non-canonical effector of EphA2 signaling duality
Authors: J Jukonen, L Moyano-Gal, K Höpfner, EA Pietilä, L Lehtinen, K Huhtinen, E Gucciardo, J Hynninen, S Hietanen, S Grénman, PM Ojala, O Carpén, K Lehti
Scientific Reports, 2021-04-23;11(1):8856.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pharmaceutical immunoglobulin G impairs anti-carcinoma activity of oxaliplatin in colon cancer cells
Authors: Y Shang, X Zhang, L Lu, K Jiang, M Krohn, S Matschos, CS Mullins, B Vollmar, D Zechner, P Gong, M Linnebache
British Journal of Cancer, 2021-02-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

SHP-1 Regulates Antigen Cross-Presentation and Is Exploited by Leishmania to Evade Immunity
Authors: S C Khouili, ECL Cook, E Hernández-, M Martínez-L, R Conde-Garr, S Iborra
Cell Rep, 2020-12-01;33(9):108468.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

ROBO2 signaling in lung development regulates SOX2/SOX9 balance, branching morphogenesis and is dysregulated in nitrofen-induced congenital diaphragmatic hernia
Authors: AN Gonçalves, J Correia-Pi, C Nogueira-S
Respir Res, 2020-11-18;21(1):302.
Species: Rat
Sample Types: Whole Cells
Applications: Cell Culture

The Oncoprotein SKI Acts as A Suppressor of NK Cell-Mediated Immunosurveillance in PDAC
Authors: V Ponath, M Frech, M Bittermann, R Al Khayer, A Neubauer, C Brendel, E Pogge von
Cancers (Basel), 2020-10-03;12(10):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Glycosaminoglycans bind human IL-27 and regulate its activity
Authors: MC Cavé, S Maillard, K Hildenbran, C Mamelonet, MJ Feige, O Devergne
Eur. J. Immunol., 2020-07-02;0(0):.
Species: Human
Sample Types: Protein
Applications: Bioassay

Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC
Authors: C Volz, S Breid, C Selenz, A Zaplatina, K Golfmann, L Meder, F Dietlein, S Borchmann, S Chatterjee, M Siobal, J Schöttle, A Florin, M Koker, M Nill, L Ozreti?, N Uhlenbrock, S Smith, R Büttner, H Miao, B Wang, HC Reinhardt, D Rauh, M Hallek, A Acker-Palm, LC Heukamp, RT Ullrich
Cell Rep, 2020-04-28;31(4):107568.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Characterization of BAY 1905254, an Immune Checkpoint Inhibitor Targeting the Immunoglobulin-Like Domain Containing Receptor 2 (ILDR2)
Authors: J Huetter, U Gritzan, I Gutcher, WD Doecke, MV Luetke-Eve, S Golfier, HG Roider, AL Frisk, J Hunter, A Pow, A Drake, Z Levine, O Levy, M Azulay, I Barbiro, G Cojocaru, I Vaknin, B Kreft, L Roese
Cancer Immunol Res, 2020-04-20;8(7):895-911.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The secreted protein DEL-1 activates a beta3 integrin-FAK-ERK1/2-RUNX2 pathway and promotes osteogenic differentiation and bone regeneration
Authors: DY Yuh, T Maekawa, X Li, T Kajikawa, K Bdeir, T Chavakis, G Hajishenga
J. Biol. Chem., 2020-04-12;295(21):7261-7273.
Species: Mouse, Transgenic Mouse
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

CD300lf is the primary physiologic receptor of murine norovirus but not human norovirus
Authors: VR Graziano, FC Walker, EA Kennedy, J Wei, K Ettayebi, MS Strine, RB Filler, E Hassan, LL Hsieh, AS Kim, AO Kolawole, CE Wobus, LC Lindesmith, RS Baric, MK Estes, RC Orchard, MT Baldridge, CB Wilen
PLoS Pathog., 2020-04-06;16(4):e1008242.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Endothelial EphB4 maintains vascular integrity and transport function in adult heart
Authors: G Luxán, J Stewen, N Díaz, K Kato, SK Maney, A Aravamudha, F Berkenfeld, N Nagelmann, HC Drexler, D Zeuschner, C Faber, H Schillers, S Hermann, J Wiseman, JM Vaquerizas, ME Pitulescu, RH Adams
Elife, 2019-11-29;8(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Increased expression of fibronectin leucine-rich transmembrane protein 3 in the dorsal root ganglion induces neuropathic pain in rats
Authors: M Yamada, Y Fujita, Y Hayano, H Hayakawa, K Baba, H Mochizuki, T Yamashita
J. Neurosci., 2019-07-25;0(0):.
Species: Human
Sample Types: Recombinant Protein
Applications: ELISA Capture

CD200R deletion promotes a neutrophil niche for Francisella tularensis and increases infectious burden and mortality
Authors: J Casulli, ME Fife, SA Houston, S Rossi, J Dow, ED Williamson, GC Clark, T Hussell, RV D'Elia, MA Travis
Nat Commun, 2019-05-09;10(1):2121.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Live nanoscopic to mesoscopic topography reconstruction with an optical microscope for chemical and biological samples
Authors: O Theodoly, N Garcia-Sey, F Bedu, X Luo, S Gabriele, T Mignot, J Giermanska, JP Chapel, M Métivier, MP Valignat
PLoS ONE, 2018-12-12;13(12):e0207881.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TBC1d24-ephrinB2 interaction regulates contact inhibition of locomotion in neural crest cell migration
Authors: J Yoon, YS Hwang, M Lee, J Sun, HJ Cho, L Knapik, IO Daar
Nat Commun, 2018-08-28;9(1):3491.
Species: Xenopus
Sample Types: Whole Cells
Applications: Bioassay

Combined blockade of IL-6 and PD-1/PD-L1 signaling abrogates mutual regulation of their immunosuppressive effects in the tumor microenvironment
Authors: H Tsukamoto, K Fujieda, A Miyashita, S Fukushima, T Ikeda, Y Kubo, S Senju, H Ihn, Y Nishimura, H Oshiumi
Cancer Res., 2018-07-02;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

NCAM2 Fibronectin type-III domains form a rigid structure that binds and activates the Fibroblast Growth Factor Receptor
Authors: KK Rasmussen, MH Falkesgaar, M Winther, NK Roed, CL Quistgaard, MN Teisen, SM Edslev, DL Petersen, A Aljubouri, C Christense, PW Thulstrup, L Lo Leggio, K Teilum, PS Walmod
Sci Rep, 2018-06-12;8(1):8957.
Applications: Bioassay

Antibody dependent cellular phagocytosis by macrophages is a novel mechanism of action of elotuzumab
Authors: AT Kurdi, SV Glavey, NA Bezman, A Jhatakia, JL Guerriero, S Manier, M Moschetta, Y Mishima, A Roccaro, A Detappe, CJ Liu, A Sacco, D Huynh, YT Tai, MD Robbins, J Azzi, IM Ghobrial
Mol. Cancer Ther., 2018-04-13;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

TREM2 Is a Receptor for ?-Amyloid that Mediates Microglial Function
Authors: Y Zhao, X Wu, X Li, LL Jiang, X Gui, Y Liu, Y Sun, B Zhu, JC Piña-Cresp, M Zhang, N Zhang, X Chen, G Bu, Z An, TY Huang, H Xu
Neuron, 2018-03-07;97(5):1023-1031.e7.
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay, Immunoprecipitation

The product of the ?-secretase processing of ephrinB2 regulates VE-cadherin complexes and angiogenesis
Authors: NA Warren, G Voloudakis, Y Yoon, NK Robakis, A Georgakopo
Cell. Mol. Life Sci., 2018-02-10;0(0):.
Species: Bovine
Sample Types: Whole Cells
Applications: Bioassay

EphrinA1-Fc attenuates myocardial ischemia/reperfusion injury in mice
Authors: A DuSablon, J Parks, K Whitehurst, H Estes, R Chase, E Vlahos, U Sharma, D Wert, J Virag
PLoS ONE, 2017-12-13;12(12):e0189307.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

Secreted protein Del-1 regulates myelopoiesis in the hematopoietic stem cell niche
Authors: I Mitroulis, LS Chen, RP Singh, I Kourtzelis, M Economopou, T Kajikawa, M Troullinak, A Ziogas, K Ruppova, K Hosur, T Maekawa, B Wang, P Subramania, T Tonn, P Verginis, M von Bonin, M Wobus, M Bornhäuser, T Grinenko, M Di Scala, A Hidalgo, B Wielockx, G Hajishenga, T Chavakis
J. Clin. Invest., 2017-08-28;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Expression, refolding and spectroscopic characterization of fibronectin type III (FnIII)-homology domains derived from human fibronectin leucine rich transmembrane protein (FLRT)-1, -2, and -3
Authors: L Yang, M Hansen Fal, PW Thulstrup, PS Walmod, L Lo Leggio, K Krighaar R
PeerJ, 2017-07-07;5(0):e3550.
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay

Interleukin-10-producing LAG3(+) regulatory T cells are associated with disease activity and abatacept treatment in rheumatoid arthritis
Authors: S Nakachi, S Sumitomo, Y Tsuchida, H Tsuchiya, M Kono, R Kato, K Sakurai, N Hanata, Y Nagafuchi, S Tateishi, H Kanda, T Okamura, K Yamamoto, K Fujio
Arthritis Res. Ther., 2017-05-16;19(1):97.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dynamic Arc SUMOylation and Selective Interaction with F-Actin-Binding Protein Drebrin A in LTP Consolidation In Vivo
Authors: RR Nair, S Patil, A Tiron, T Kanhema, D Panja, L Schiro, K Parobczak, G Wilczynski, CR Bramham
Front Synaptic Neurosci, 2017-05-10;9(0):8.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Semaphorin 3A Increases FAK Phosphorylation at Focal Adhesions to Modulate MDA-MB-231 Cell Migration and Spreading on Different Substratum Concentrations
Authors: S Gehler, FV Compere, AM Miller
Int J Breast Cancer, 2017-01-15;2017(0):9619734.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ICAM-5/Telencephalin Is a Functional Entry Receptor for Enterovirus D68
Authors: Wei Wei
Cell Host Microbe, 2016-10-27;20(5):631-641.
Applications: Bioassay

Tissue factor is induced by interleukin-33 in human endothelial cells: a new link between coagulation and inflammation
Sci Rep, 2016-05-04;6(0):25171.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Semaphorin 7A Aggravates Pulmonary Inflammation during Lung Injury.
Authors: Roth J, Kohler D, Schneider M, Granja T, Rosenberger P
PLoS ONE, 2016-01-11;11(1):e0146930.
Species: Human
Sample Types: Whole Cells
Applications: Control

Interleukin-21 Induces Proliferation and Proinflammatory Cytokine Profile of Fibroblast-like Synoviocytes of Patients with Rheumatoid Arthritis.
Authors: Xing R, Yang L, Jin Y, Sun L, Li C, Li Z, Zhao J, Liu X
Scand J Immunol, 2016-01-01;83(1):64-71.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mutant B-Raf(V600E) Promotes Melanoma Paracellular Transmigration by Inducing Thrombin-mediated Endothelial Junction Breakdown.
Authors: Zhang P, Feng S, Liu G, Wang H, Zhu H, Ren Q, Bai H, Fu C, Dong C
J Biol Chem, 2015-10-26;291(5):2087-106.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Aspirin-Exacerbated Respiratory Disease Involves a Cysteinyl Leukotriene-Driven IL-33-Mediated Mast Cell Activation Pathway.
Authors: Liu T, Kanaoka Y, Barrett N, Feng C, Garofalo D, Lai J, Buchheit K, Bhattacharya N, Laidlaw T, Katz H, Boyce J
J Immunol, 2015-09-04;195(8):3537-45.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

NKP30-B7-H6 Interaction Aggravates Hepatocyte Damage through Up-Regulation of Interleukin-32 Expression in Hepatitis B Virus-Related Acute-On-Chronic Liver Failure.
Authors: Zou Y, Bao J, Pan X, Lu Y, Liao S, Wang X, Wang G, Lin D
PLoS ONE, 2015-08-04;10(8):e0134568.
Species: Human
Sample Types: Whole Cells
Applications: Control

Receptor tyrosine kinase Axl is required for resistance of leukemic cells to FLT3-targeted therapy in acute myeloid leukemia.
Authors: Park I, Mundy-Bosse B, Whitman S, Zhang X, Warner S, Bearss D, Blum W, Marcucci G, Caligiuri M
Leukemia, 2015-06-19;29(12):2382-9.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The paradox of high availability and low recognition of soluble HLA-G by LILRB1 receptor in rheumatoid arthritis patients.
Authors: Veit T, Chies J, Switala M, Wagner B, Horn P, Busatto M, Brenol C, Tavares Brenol J, Machado Xavier R, Rebmann V
PLoS ONE, 2015-04-08;10(4):e0123838.
Species: Human
Sample Types: Protein
Applications: Bioassay

EphrinB2 controls vessel pruning through STAT1-JNK3 signalling.
Authors: Salvucci O, Ohnuki H, Maric D, Hou X, Li X, Yoon S, Segarra M, Eberhart C, Acker-Palmer A, Tosato G
Nat Commun, 2015-03-26;6(0):6576.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IL-24 inhibits lung cancer cell migration and invasion by disrupting the SDF-1/CXCR4 signaling axis.
Authors: Panneerselvam J, Jin J, Shanker M, Lauderdale J, Bates J, Wang Q, Zhao Y, Archibald S, Hubin T, Ramesh R
PLoS ONE, 2015-03-16;10(3):e0122439.
Species: Human
Sample Types: Whole Cells

Epithelial and stromal cell urokinase plasminogen activator receptor expression differentially correlates with survival in rectal cancer stages B and C patients.
Authors: Ahn, Seong Be, Chan, Charles, Dent, Owen F, Mohamedali, Abidali, Kwun, Sun Youn, Clarke, Candice, Fletcher, Julie, Chapuis, Pierre H, Nice, Edouard, Baker, Mark S
PLoS ONE, 2015-02-18;10(2):e0117786.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P

ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.
Authors: Herova M, Schmid M, Gemperle C, Hersberger M
J Immunol, 2015-01-30;194(5):2330-7.
Species: Human
Sample Types: Whole Cells
Applications: Isotype Control

Different patterns of electrical activity lead to long-term potentiation by activating different intracellular pathways.
Authors: Zhu G, Liu Y, Wang Y, Bi X, Baudry M
J Neurosci, 2015-01-14;35(2):621-33.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control

Chemokine-coupled beta2 integrin-induced macrophage Rac2-Myosin IIA interaction regulates VEGF-A mRNA stability and arteriogenesis.
Authors: Morrison A, Yarovinsky T, Young B, Moraes F, Ross T, Ceneri N, Zhang J, Zhuang Z, Sinusas A, Pardi R, Schwartz M, Simons M, Bender J
J Exp Med, 2014-09-01;211(10):1957-68.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Development of the prethalamus is crucial for thalamocortical projection formation and is regulated by Olig2.
Authors: Ono, Katsuhik, Clavairoly, Adrien, Nomura, Tadashi, Gotoh, Hitoshi, Uno, Aoi, Armant, Olivier, Takebayashi, Hirohide, Zhang, Qi, Shimamura, Kenji, Itohara, Shigeyos, Parras, Carlos M, Ikenaka, Kazuhiro
Development, 2014-05-01;141(10):2075-84.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

A polysaccharide virulence factor of a human fungal pathogen induces neutrophil apoptosis via NK cells.
Authors: Robinet P, Baychelier F, Fontaine T, Picard C, Debre P, Vieillard V, Latge J, Elbim C
J Immunol, 2014-04-30;192(11):5332-42.
Species: Human
Sample Types: Whole Blood
Applications: Isotype Control

Dynorphin up-regulation in the dentate granule cell mossy fiber pathway following chronic inhibition of GluN2B-containing NMDAR is associated with increased CREB (Ser 133) phosphorylation, but is independent of BDNF/TrkB signaling pathways.
Authors: Rittase, W Bradle, Dong, Yu, Barksdale, DaRel, Galdzicki, Zygmunt, Bausch, Suzanne
Mol Cell Neurosci, 2014-04-23;60(0):63-71.
Species: Rat
Sample Types: Whole Tissue
Applications: Control

VISTA is an immune checkpoint molecule for human T cells.
Authors: Lines J, Pantazi E, Mak J, Sempere L, Wang L, O'Connell S, Ceeraz S, Suriawinata A, Yan S, Ernstoff M, Noelle R
Cancer Res, 2014-04-01;74(7):1924-32.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The endocannabinoid/endovanilloid N-arachidonoyl dopamine (NADA) and synthetic cannabinoid WIN55,212-2 abate the inflammatory activation of human endothelial cells.
Authors: Wilhelmsen K, Khakpour S, Tran A, Sheehan K, Schumacher M, Xu F, Hellman J
J Biol Chem, 2014-03-18;289(19):13079-100.
Species: Human
Sample Types: Whole Cells

Ovine carotid artery-derived cells as an optimized supportive cell layer in 2-D capillary network assays.
Authors: Weinandy, Stefan, Babczyk, Patrick, Dreier, Agnieszk, Unger, Ronald E, Flanagan, Thomas C, Kirkpatrick, C James, Zenke, Martin, Klee, Doris, Jockenhoevel, Stefan
PLoS ONE, 2014-03-12;9(3):e91664.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control

Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
Authors: Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K
Nat Med, 2014-03-02;20(4):377-84.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Novaferon, a novel recombinant protein produced by DNA-shuffling of IFN-alpha, shows antitumor effect in vitro and in vivo.
Authors: Li M, Rao C, Pei D, Wang L, Li Y, Gao K, Wang M, Wang J
Cancer Cell Int, 2014-01-27;14(1):8.
Applications: Surface Plasmon Resonance

TNF-alpha blockade induces IL-10 expression in human CD4+ T cells.
Authors: Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, Sumner J, Baeten D, Gerwien J, Cope A, Geissmann F, Kirkham B, Taams L
Nat Commun, 2014-01-01;5(0):3199.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Soluble beta-amyloid Precursor Protein Alpha binds to p75 neurotrophin receptor to promote neurite outgrowth.
Authors: Hasebe N, Fujita Y, Ueno M, Yoshimura K, Fujino Y, Yamashita T
PLoS ONE, 2013-12-16;8(12):e82321.
Species: Human
Sample Types: Recombinant Protein
Applications: Functional ELISA

Changes of peripheral TGF-beta1 depend on monocytes-derived macrophages in Huntington disease.
Authors: Di Pardo A, Alberti S, Maglione V, Amico E, Cortes E, Elifani F, Battaglia G, Busceti C, Nicoletti F, Vonsattel J, Squitieri F
Mol Brain, 2013-12-13;6(0):55.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry Control

Role of synaptic plasticity and EphA5-ephrinA5 interaction within the ventromedial hypothalamus in response to recurrent hypoglycemia.
Authors: Szepietowska, Barbara, Horvath, Tamas L, Sherwin, Robert S
Diabetes, 2013-11-12;63(3):1140-7.
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Bromelain decreases neutrophil interactions with P-selectin, but not E-selectin, in vitro by proteolytic cleavage of P-selectin glycoprotein ligand-1.
Authors: Banks, Jessica, Herman, Christin, Bailey, Ryan C
PLoS ONE, 2013-11-11;8(11):e78988.
Applications: Bioassay

NKG2D triggers cytotoxicity in murine epidermal gammadelta T cells via PI3K-dependent, Syk/ZAP70-independent signaling pathway.
Authors: Ibusuki A, Kawai K, Yoshida S, Uchida Y, Nitahara-Takeuchi A, Kuroki K, Kajikawa M, Ose T, Maenaka K, Kasahara M, Kanekura T
J Invest Dermatol, 2013-08-20;134(2):396-404.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

CRTAM receptor engagement by Necl-2 on tumor cells triggers cell death of activated Vgamma9Vdelta2 T cells.
Authors: Dessarthe B, Thedrez A, Latouche J, Cabillic F, Drouet A, Daniel P, de La Pintiere C, Catros V, Toutirais O
J Immunol, 2013-03-25;190(9):4868-76.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Blood CD4+CD45RO+CXCR5+ T cells are decreased but partially functional in signal transducer and activator of transcription 3 deficiency.
Authors: Mazerolles F, Picard C, Kracker S, Fischer A, Durandy A
J Allergy Clin Immunol, 2013-02-10;131(4):1146-56, 1156.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

EphA5-EphrinA5 interactions within the ventromedial hypothalamus influence counterregulatory hormone release and local glutamine/glutamate balance during hypoglycemia.
Authors: Szepietowska B, Zhu W, Czyzyk J, Eid T, Sherwin R
Diabetes, 2012-12-28;62(4):1282-8.
Species: Rat
Sample Types: In Vivo

Up-regulation of a death receptor renders antiviral T cells susceptible to NK cell-mediated deletion.
Authors: Peppa, Dimitra, Gill, Upkar S, Reynolds, Gary, Easom, Nicholas, Pallett, Laura J, Schurich, Anna, Micco, Lorenzo, Nebbia, Gaia, Singh, Harsimra, Adams, David H, Kennedy, Patrick, Maini, Mala K
J Exp Med, 2012-12-17;210(1):99-114.
Species: Human
Sample Types: Whole Cells
Applications: Control

Interleukin-33 overexpression is associated with gamma-glutamyl transferase in biliary atresia.
Cytokine, 2012-11-22;61(2):433-7.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Semaphorin 6A regulates angiogenesis by modulating VEGF signaling.
Authors: Segarra, Marta, Ohnuki, Hidetaka, Maric, Dragan, Salvucci, Ombretta, Hou, Xu, Kumar, Anil, Li, Xuri, Tosato, Giovanna
Blood, 2012-09-24;120(19):4104-15.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The alarmin IL-33 is a notch target in quiescent endothelial cells.
Authors: Sundlisaeter E, Edelmann R, Hol J, Sponheim J, Kuchler A, Weiss M, Udalova I, Midwood K, Kasprzycka M, Haraldsen G
Am J Pathol, 2012-07-16;181(3):1099-111.
Species: Human
Sample Types: Whole Cells
Applications: Control

Receptor activator of nuclear factor kappaB ligand (RANKL) protein expression by B lymphocytes contributes to ovariectomy-induced bone loss.
Authors: Onal M, Xiong J, Chen X, Thostenson J, Almeida M, Manolagas S
Oncogene, 2012-07-10;287(35):29851-60.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

IL-15 Expression on RA Synovial Fibroblasts Promotes B Cell Survival.
Authors: Benito-Miguel M, Garcia-Carmona Y, Balsa A, Bautista-Caro MB, Arroyo-Villa I, Cobo-Ibanez T, Bonilla-Hernan MG, De Ayala CP, Sanchez-Mateos P, Martin-Mola E, Miranda-Carus ME
PLoS ONE, 2012-07-09;7(7):e40620.
Species: Human
Sample Types: Whole Cells
Applications: Control

DcR3 binds to ovarian cancer via heparan sulfate proteoglycans and modulates tumor cells response to platinum with corresponding alteration in the expression of BRCA1.
BMC Cancer, 2012-05-14;12(0):176.
Species: Human
Sample Types: Whole Cells
Applications: Control

Identification of TLT2 as an engulfment receptor for apoptotic cells.
Authors: de Freitas A, Banerjee S, Xie N
J. Immunol., 2012-05-09;188(12):6381-8.
Species: Mouse
Sample Types: In Vivo
Applications: In Vivo

The mouse IAPE endogenous retrovirus can infect cells through any of the five GPI-anchored Ephrin A proteins.
Authors: Dewannieux M, Vernochet C, Ribet D, Bartosch B, Cosset FL, Heidmann T
PLoS Pathog., 2011-10-20;7(10):e1002309.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control

Slit-Robo signals regulate pioneer axon pathfinding of the tract of the postoptic commissure in the mammalian forebrain.
Authors: Ricano-Cornejo I, Altick AL, Garcia-Pena CM, Nural HF, Echevarria D, Miquelajauregui A, Mastick GS, Varela-Echavarria A
J. Neurosci. Res., 2011-06-17;89(10):1531-41.
Species: Mouse
Sample Types: Whole Tissue

Angiocrine factors modulate tumor proliferation and motility through EphA2 repression of Slit2 tumor suppressor function in endothelium.
Authors: Brantley-Sieders DM, Dunaway CM, Rao M
Cancer Res., 2010-12-08;71(3):976-87.
Species: Mouse
Sample Types: In Vivo
Applications: Control

EphB signaling controls lineage plasticity of adult neural stem cell niche cells.
Authors: Nomura T, Goritz C, Catchpole T, Henkemeyer M, Frisen J
Cell Stem Cell, 2010-12-03;7(6):730-43.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Exogenous recombinant dimeric neuropilin-1 is sufficient to drive angiogenesis.
Authors: Uniewicz KA, Cross MJ, Fernig DG
J. Biol. Chem., 2010-10-18;286(1):12-23.
Species: Human
Sample Types: Whole Cells
Applications: Control

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis.
Authors: Sawamiphak S, Seidel S, Essmann CL, Wilkinson GA, Pitulescu ME, Acker T, Acker-Palmer A
Nature, 2010-05-05;465(7297):487-91.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control

Derepression of an endogenous long terminal repeat activates the CSF1R proto-oncogene in human lymphoma.
Authors: Lamprecht B, Walter K, Kreher S, Kumar R, Hummel M, Lenze D, Kochert K, Bouhlel MA, Richter J, Soler E, Stadhouders R, Johrens K, Wurster KD, Callen DF, Harte MF, Giefing M, Barlow R, Stein H, Anagnostopoulos I, Janz M, Cockerill PN, Siebert R, Dorken B, Bonifer C, Mathas S
Nat. Med., 2010-05-02;16(5):571-9.
Species: Human
Sample Types: Whole Cells
Applications: Control

VEGF-A expression by HSV-1-infected cells drives corneal lymphangiogenesis.
Authors: Wuest TR, Carr DJ
J. Exp. Med., 2009-12-21;207(1):101-15, S1-2.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Scavenger receptor B2 is a cellular receptor for enterovirus 71.
Authors: Yamayoshi S, Yamashita Y, Li J, Hanagata N, Minowa T, Takemura T, Koike S
Nat. Med., 2009-06-21;15(7):798-801.
Species: Human
Sample Types: Peptide
Applications: Bioassay

Galectin-8 interacts with podoplanin and modulates lymphatic endothelial cell functions.
Authors: Cueni LN, Detmar M
Exp. Cell Res., 2009-03-04;315(10):1715-23.
Species: Human
Sample Types: Buffer
Applications: Control

Cross-linking of B7-H1 on EBV-transformed B cells induces apoptosis through reactive oxygen species production, JNK signaling activation, and fasL expression.
Authors: Kim YS, Park GB, Lee HK, Song H, Choi IH, Lee WJ, Hur DY
J. Immunol., 2008-11-01;181(9):6158-69.
Species: Human
Sample Types: Whole Cells
Applications: Control

IL-4 inhibits VLA-4 expression on Tc1 cells resulting in poor tumor infiltration and reduced therapy benefit.
Authors: Sasaki K, Pardee AD, Okada H, Storkus WJ
Eur. J. Immunol., 2008-10-01;38(10):2865-73.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

p75(NTR) mediates ephrin-A reverse signaling required for axon repulsion and mapping.
Authors: Lim YS, McLaughlin T, Sung TC, Santiago A, Lee KF, O'Leary DD
Neuron, 2008-09-11;59(5):746-58.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control

Temporal regulation of ephrin/Eph signalling is required for the spatial patterning of the mammalian striatum.
Authors: Passante L, Gaspard N, Degraeve M, Frisen J, Kullander K, De Maertelaer V, Vanderhaeghen P
Development, 2008-08-28;135(19):3281-90.
Species: Mouse
Sample Types: Whole Tissue

Blockade of EphB2 enhances neurogenesis in the subventricular zone and improves neurological function after cerebral cortical infarction in hypertensive rats.
Authors: Xing S, He Y, Ling L, Hou Q, Yu J, Zeng J, Pei Z
Brain Res., 2008-07-02;1230(0):237-46.
Species: Rat
Sample Types: In Vivo
Applications: Control

Intrinsic sensor of oncogenic transformation induces a signal for innate immunosurveillance.
Authors: Unni AM, Bondar T, Medzhitov R
Proc. Natl. Acad. Sci. U.S.A., 2008-01-25;105(5):1686-91.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

Plasticity of neuron-glial interactions mediated by astrocytic EphARs.
Authors: Nestor MW, Mok LP, Tulapurkar ME, Thompson SM
J. Neurosci., 2007-11-21;27(47):12817-28.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control

Extracellular stimuli specifically regulate localized levels of individual neuronal mRNAs.
Authors: Willis DE, van Niekerk EA, Sasaki Y, Mesngon M, Merianda TT, Williams GG, Kendall M, Smith DS, Bassell GJ, Twiss JL
J. Cell Biol., 2007-09-04;178(6):965-80.
Species: Rat
Sample Types: Whole Cells
Applications: Control

CD86 regulates IgG1 production via a CD19-dependent mechanism.
Authors: Kin NW, Sanders VM
J. Immunol., 2007-08-01;179(3):1516-23.
Species: Mouse
Sample Types: Whole Cells
Applications: Control

Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
Crit. Care Med., 2007-08-01;35(8):1955-60.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Global DNA methylation profiling reveals silencing of a secreted form of Epha7 in mouse and human germinal center B-cell lymphomas.
Authors: Dawson DW, Hong JS, Shen RR, French SW, Troke JJ, Wu YZ, Chen SS, Gui D, Regelson M, Marahrens Y, Morse HC, Said J, Plass C, Teitell MA
Oncogene, 2007-01-29;26(29):4243-52.
Species: Human
Sample Types: Whole Cells
Applications: Control

Nonvascular VEGF receptor 3 expression by corneal epithelium maintains avascularity and vision.
Authors: Cursiefen C, Chen L, Saint-Geniez M, Hamrah P, Jin Y, Rashid S, Pytowski B, Persaud K, Wu Y, Streilein JW, Dana R
Proc. Natl. Acad. Sci. U.S.A., 2006-07-18;103(30):11405-10.
Species: Mouse
Sample Types: In Vivo
Applications: Control

Induction of ephrin-B1 and EphB receptors during denervation-induced plasticity in the adult mouse hippocampus.
Authors: Wang Y, Ying GX, Liu X, Wang WY, Dong JH, Ni ZM, Zhou CF
Eur. J. Neurosci., 2005-05-01;21(9):2336-46.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control

Nurselike cells express BAFF and APRIL, which can promote survival of chronic lymphocytic leukemia cells via a paracrine pathway distinct from that of SDF-1alpha.
Authors: Nishio M, Endo T, Tsukada N, Ohata J, Kitada S, Reed JC, Zvaifler NJ, Kipps TJ
Blood, 2005-04-28;106(3):1012-20.
Species: Human
Sample Types: Whole Cells
Applications: Control

The cytolethal distending toxin induces receptor activator of NF-kappaB ligand expression in human gingival fibroblasts and periodontal ligament cells.
Authors: Belibasakis GN, Johansson A, Wang Y, Chen C, Kalfas S, Lerner UH
Infect. Immun., 2005-01-01;73(1):342-51.
Species: Human
Sample Types: Whole Cells
Applications: Control

FGF8 dose-dependent regulation of embryonic submandibular salivary gland morphogenesis.
Authors: Jaskoll T, Witcher D, Toreno L, Bringas P, Moon AM, Melnick M
Dev. Biol., 2004-04-15;268(2):457-69.
Species: Mouse
Sample Types: Whole Cells

Antiangiogenic and antitumor efficacy of EphA2 receptor antagonist.
Authors: Dobrzanski P, Hunter K, Jones-Bolin S, Chang H, Robinson C, Pritchard S, Zhao H, Ruggeri B
Cancer Res., 2004-02-01;64(3):910-9.
Species: Rat
Sample Types: Whole Cells
Applications: Control

Wnt regulation of progenitor maturation in the cortex depends on Shh or fibroblast growth factor 2.
Authors: Viti J, Gulacsi A, Lillien L
J. Neurosci., 2003-07-02;23(13):5919-27.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control

Control of hippocampal dendritic spine morphology through ephrin-A3/EphA4 signaling.
Authors: Murai KK, Nguyen LN, Irie F, Yamaguchi Y, Pasquale EB
Nat. Neurosci., 2003-02-01;6(2):153-60.
Species: Mouse
Sample Types: Whole Tissue
Applications: Control