Recombinant Human IFN-gamma Protein

GMP Version Available: 285-GMP
GMP
Analyzed by SEC-MALS

Carrier Free

Catalog # Availability Size / Price Qty
285-IF-100/CF

With Carrier

Catalog # Availability Size / Price Qty
285-IF-100
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Recombinant Human IFN‑ gamma  Protein SEC-MALS.
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Product Details
Citations (446)
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Recombinant Human IFN-gamma Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.01 EU per 1 μg of the protein by the LAL method.
Activity
Measured in anti-viral assays using HeLa human cervical epithelial carcinoma cells infected with encephalomyocarditis (EMC) virus. Meager, A. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 129. The ED50 for this effect is 0.15-0.75 ng/mL.
Source
E. coli-derived human IFN-gamma protein
Gln24-Gln166 with an N-terminal Met
Accession #
N-terminal Sequence
Analysis
Met
Predicted Molecular Mass
16.9 kDa
SDS-PAGE
17 kDa, reducing conditions

Product Datasheets

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285-IF (with carrier)

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285-IF/CF (carrier free)

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

285-IF

Formulation Lyophilized from a 0.2 μm filtered solution in Sodium Succinate, Mannitol and Tween® 80 with BSA as a carrier protein.
Reconstitution Reconstitute at 0.2 mg/mL in sterile, deionized water.  
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

285-IF/CF

Formulation Lyophilized from a 0.2 μm filtered solution in Sodium Succinate, Mannitol and Tween® 80.
Reconstitution Reconstitute at 0.2 mg/mL in sterile, deionized water. 
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Scientific Data

SEC-MALS View Larger

Recombinant Human IFN-gamma (Catalog # 285-IF) has a molecular weight (MW) of 34.9 kDa as analyzed by SEC-MALS, suggesting that this protein is a homodimer.  MW may differ from predicted MW due to post-translational modifications (PTMs) present (i.e. Glycosylation).

SDS-PAGE Recombinant Human IFN-gamma Protein SDS-PAGE View Larger

1 μg/lane of Recombinant Human IFN-gamma was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 17 kDa.

Bioactivity Recombinant Human IFN-gamma Protein Bioactivity View Larger

Recombinant Human IFN-gamma (Catalog # 285‑IF) demonstrates anti-viral activity in HeLa human cervical epithelial carcinoma cells infected with encephalomyocarditis (EMC) virus. The activity is over 2-fold greater than the top competitor's IFN-gamma.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IFN-gamma

Interferon-gamma (IFN-gamma ), also known as type II or immune interferon, exerts a wide range of immunoregulatory activities and is considered to be the prototype proinflammatory cytokine (1, 2). Mature human IFN-gamma exists as a non-covalently linked homodimer of 20-25 kDa variably glycosylated subunits (3). It shares 90% amino acid (aa) sequence identity with rhesus IFN-gamma, 59%‑64% with bovine, canine, equine, feline, and porcine IFN‑ gamma, and 37%‑43% with cotton rat, mouse, and rat IFN-gamma. IFN-gamma dimers bind to IFN-gamma RI ( alpha subunits) which then interact with IFN-gamma RII ( beta  subunits) to form the functional receptor complex of two alpha and two beta  subunits. Inclusion of IFN-gamma RII increases the binding affinity for ligand and the efficiency of signal transduction (4, 5). IFN-gamma is produced by a variety of immune cells under inflammatory conditions, notably by T cells and NK cells (6). It plays a key role in host defense by promoting the development and activation of Th1 cells, chemoattraction and activation of monocytes and macrophages, up‑regulation of antigen presentation molecules, and immunoglobulin class switching in B cells. It also exhibits antiviral, antiproliferative, and apoptotic effects (6, 7). In addition, IFN-gamma functions as an anti-inflammatory mediator by promoting the development of regulatory T cells and inhibiting Th17 cell differentiation (8, 9). The pleiotropic effects of IFN-gamma contribute to the development of multiple aspects of atherosclerosis (7).

References
  1. Billiau, A. and P. Matthys (2009) Cytokine Growth Factor Rev. 20:97.
  2. Pestka, S. et al. (2004) Immunol. Rev. 202:8.
  3. Gray, P.W. and D.V. Goeddel (1982) Nature 298:859.
  4. Marsters, S.A. et al. (1995) Proc. Natl. Acad. Sci. 92:5401.
  5. Krause, C.D. et al. (2000) J. Biol. Chem. 275:22995.
  6. Schroder, K. et al. (2004) J. Leukoc. Biol. 75:163.
  7. McLaren, J.E. and D.P. Ramji (2009) Cytokine Growth Factor Rev. 20:125.
  8. Muhl, H. and J. Pfeilschifter (2003) Int. Immunopharmacol. 3:1247.
  9. Kelchtermans, H. et al. (2008) Trends Immunol. 29:479.
Long Name
Interferon gamma
Entrez Gene IDs
3458 (Human); 15978 (Mouse); 25712 (Rat); 396991 (Porcine); 281237 (Bovine); 403801 (Canine); 493965 (Feline)
Alternate Names
IFG; IFI; IFNG; IFNgamma; IFN-gamma; Immune interferon; interferon gamma; interferon, gamma

Citations for Recombinant Human IFN-gamma Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

446 Citations: Showing 1 - 10
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  1. Replication competent HIV-guided CRISPR screen identifies antiviral factors including targets of the accessory protein Nef
    Authors: Prelli Bozzo, C;Laliberté, A;De Luna, A;Pastorio, C;Regensburger, K;Krebs, S;Graf, A;Blum, H;Volcic, M;Sparrer, KMJ;Kirchhoff, F;
    Nature communications
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  2. A murine model to evaluate immunotherapy effectiveness for human Fanconi anemia-mutated acute myeloid leukemia
    Authors: Huang, T;Leung, B;Huang, Y;Price, L;Gui, J;Lau, BW;
    PloS one
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Engagement of CD99 activates distinct programs in Ewing sarcoma and macrophages
    Authors: Manara, MC;Manferdini, C;Cristalli, C;Carrabotta, M;Santi, S;De Feo, A;Caldoni, G;Pasello, M;Landuzzi, L;Lollini, PL;Salamanna, F;Dominici, S;Fiori, V;Magnani, M;Lisignoli, G;Scotlandi, K;
    Cancer immunology research
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Investigation into the role of the MITA-TRIM38 interaction in regulating pyroptosis and maintaining immune tolerance at the maternal-fetal interface
    Authors: Liu, J;Deng, Y;Wang, A;Liu, B;Zhou, X;Yin, T;Wang, Y;Tang, T;Qiu, Y;Chen, J;Yang, J;
    Cell death & disease
    Species: Human
    Sample Types: Transduced Whole Cells, Whole Cells
    Applications: Bioassay
  5. Identification of the Functional PD-L1 Interface Region Responsible for PD-1 Binding and Initiation of PD-1 Signaling
    Authors: Carter, R;Alanazi, F;Sharp, A;Roman, J;Luchini, A;Liotta, L;Paige, M;Brown, AM;Haymond, A;
    The Journal of biological chemistry
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Influence of Macrophages on Vascular Invasion of Inflammatory Breast Cancer Emboli Measured Using an In Vitro Microfluidic Multi-Cellular Platform
    Authors: Gadde, M;Mehrabi-Dehdezi, M;Debeb, BG;Woodward, WA;Rylander, MN;
    Cancers
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Mapping the epigenomic landscape of human monocytes following innate immune activation reveals context-specific mechanisms driving endotoxin tolerance
    Authors: Amarasinghe, HE;Zhang, P;Whalley, JP;Allcock, A;Migliorini, G;Brown, AC;Scozzafava, G;Knight, JC;
    BMC genomics
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Tyrosine phosphorylation of IRF3 by BLK facilitates its sufficient activation and innate antiviral response
    Authors: Li, WW;Fan, XX;Zhu, ZX;Cao, XJ;Zhu, ZY;Pei, DS;Wang, YZ;Zhang, JY;Wang, YY;Zheng, HX;
    PLoS pathogens
    Species: Human
    Sample Types: Transfected Whole Cells
    Applications: Bioassay
  9. Human GBP1 facilitates the rupture of the Legionella-containing vacuole and inflammasome activation
    Authors: Bass, AR;Egan, MS;Alexander-Floyd, J;Lopes Fischer, N;Doerner, J;Shin, S;
    mBio
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Regulation of human interferon signaling by transposon exonization
    Authors: Pasquesi, GIM;Allen, H;Ivancevic, A;Barbachano-Guerrero, A;Joyner, O;Guo, K;Simpson, DM;Gapin, K;Horton, I;Nguyen, L;Yang, Q;Warren, CJ;Florea, LD;Bitler, BG;Santiago, ML;Sawyer, SL;Chuong, EB;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. DUX4 expression in cancer induces a metastable early embryonic totipotent program
    Authors: Smith, AA;Nip, Y;Bennett, SR;Hamm, DC;Lemmers, RJLF;van der Vliet, PJ;Setty, M;van der Maarel, SM;Tapscott, SJ;
    Cell reports
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Comprehensive analysis of E47?like factors and verification of ELF4 in clear cell renal cell carcinoma
    Authors: Lu, J;Zhang, Q;Mo, L;Chen, W;Mao, L;
    Oncology letters
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Macrophage Profiling in Head and Neck Cancer to Improve Patient Prognosis and Assessment of Cancer Cell-Macrophage Interactions Using Three-Dimensional Coculture Models
    Authors: Mhaidly, N;Journe, F;Najem, A;Stock, L;Trelcat, A;Dequanter, D;Saussez, S;Descamps, G;
    International journal of molecular sciences
    Species: Human
    Sample Types: Spheroids
    Applications: Bioassay
  14. Plug-and-play protein biosensors using aptamer-regulated in vitro transcription
    Authors: Lee, H;Xie, T;Yu, X;Schaffter, SW;Schulman, R;
    bioRxiv : the preprint server for biology
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  15. Inhibition of METTL3 results in a cell-intrinsic interferon response that enhances anti-tumour immunity
    Authors: Guirguis, AA;Ofir-Rosenfeld, Y;Knezevic, K;Blackaby, W;Hardick, D;Chan, YC;Motazedian, A;Gillespie, A;Vassiliadis, D;Lam, EY;Tran, K;Andrews, B;Harbour, ME;Vasiliauskaite, L;Saunders, CJ;Tsagkogeorga, G;Azevedo, A;Obacz, J;Pilka, ES;Carkill, M;MacPherson, L;Wainwright, EN;Liddicoat, B;Blyth, BJ;Albertella, MR;Rausch, O;Dawson, MA;
    Cancer discovery
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  16. Exosome from IFN-gamma -Primed Induced Pluripotent Stem Cell-Derived Mesenchymal Stem Cells Improved Skin Inflammation and Barrier Function
    Authors: Yoon, J;Lee, SK;Park, A;Lee, J;Jung, I;Song, KB;Choi, EJ;Kim, S;Yu, J;
    International journal of molecular sciences
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  17. Senescence-Driven Inflammatory and Trophic Microenvironment Imprints Mesenchymal Stromal/Stem Cells in Osteoarthritic Patients
    Authors: Fusi, G;Constantinides, M;Fissoun, C;Pichard, L;Pers, YM;Ferreira-Lopez, R;Pantesco, V;Poulet, C;Malaise, O;De Seny, D;Lemaitre, JM;Jorgensen, C;Brondello, JM;
    Biomedicines
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  18. PLSCR1 is a cell-autonomous defence factor against SARS-CoV-2 infection
    Authors: Xu, D;Jiang, W;Wu, L;Gaudet, RG;Park, ES;Su, M;Cheppali, SK;Cheemarla, NR;Kumar, P;Uchil, PD;Grover, JR;Foxman, EF;Brown, CM;Stansfeld, PJ;Bewersdorf, J;Mothes, W;Karatekin, E;Wilen, CB;MacMicking, JD;
    Nature
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  19. Dynamics of Ex Vivo Mesenchymal Stromal Cell Potency under Continuous Perfusion
    Authors: Doshi, A;Erickson, P;Teryek, M;Parekkadan, B;
    International journal of molecular sciences
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  20. High levels of endothelial ICAM-1 prohibit natalizumab mediated abrogation of CD4+ T cell arrest on the inflamed BBB under flow in vitro
    Authors: Soldati, S;B�r, A;Vladymyrov, M;Glavin, D;McGrath, JL;Gosselet, F;Nishihara, H;Goelz, S;Engelhardt, B;
    Journal of neuroinflammation
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. The HDAC2-SP1 axis orchestrates pro-tumor macrophage polarization
    Authors: Zheng, X;Sarode, P;Weigert, A;Turkowski, K;Chelladurai, P;G�nther, S;Kuenne, C;Winter, H;Stenzinger, A;Reu, S;Grimminger, F;Stiewe, T;Seeger, W;Pullamsetti, SS;Savai, R;
    Cancer research
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Small-molecule PIK-93 modulates the tumor microenvironment to improve immune checkpoint blockade response
    Authors: CY Lin, KY Huang, SH Kao, MS Lin, CC Lin, SC Yang, WC Chung, YH Chang, RJ Chein, PC Yang
    Science Advances, 2023-04-07;9(14):eade9944.
    Species: Human
    Sample Types: Whole Cell
    Applications: Bioassay
  23. Aryl hydrocarbon receptor activity downstream of IL-10 signaling is required to promote regulatory functions in human dendritic cells
    Authors: D Avancini, A Testori, L Fresolone, G Andolfi, M Vuono, V Martinelli, FR Santoni de, S Gregori
    Cell Reports, 2023-03-03;42(3):112193.
    Species: Human
    Sample Types: Protein
    Applications: Reference Standard
  24. PD-1highCXCR5-CD4+ peripheral helper T�cells promote CXCR3+ plasmablasts in human acute viral infection
    Authors: H Asashima, S Mohanty, M Comi, WE Ruff, KB Hoehn, P Wong, J Klein, C Lucas, I Cohen, S Coffey, N Lele, L Greta, K Raddassi, O Chaudhary, A Unterman, B Emu, SH Kleinstein, RR Montgomery, A Iwasaki, CS Dela Cruz, N Kaminski, AC Shaw, DA Hafler, TS Sumida
    Cell Reports, 2023-01-02;0(0):111895.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  25. Intestinal epithelial BLT1 promotes mucosal repair
    Authors: S Hayashi, CK Muraleedha, M Oku, S Tomar, SP Hogan, M Quiros, CA Parkos, A Nusrat
    JCI Insight, 2022-12-08;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  26. CRISPR/Cas9 Edited RAS & MEK Mutant Cells Acquire BRAF and MEK Inhibitor Resistance with MEK1 Q56P Restoring Sensitivity to MEK/BRAF Inhibitor Combo and KRAS G13D Gaining Sensitivity to Immunotherapy
    Authors: E Turner, L Chen, JG Foulke, Z Gu, F Tian
    Cancers, 2022-11-05;14(21):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel disease
    Authors: P Pavlidis, A Tsakmaki, A Treveil, K Li, D Cozzetto, F Yang, U Niazi, BH Hayee, M Saqi, J Friedman, T Korcsmaros, G Bewick, N Powell
    Cell Reports, 2022-09-27;40(13):111439.
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  28. NAD+ metabolism drives astrocyte proinflammatory reprogramming in central nervous system autoimmunity
    Authors: T Meyer, D Shimon, S Youssef, G Yankovitz, A Tessler, T Chernobyls, A Gaoni-Yoge, R Perelroize, N Budick-Har, L Steinman, L Mayo
    Proceedings of the National Academy of Sciences of the United States of America, 2022-08-22;119(35):e2211310119.
    Species: Human
    Sample Types: Whole Cell
    Applications: Cell Culture
  29. STUB1 is an intracellular checkpoint for interferon gamma sensing
    Authors: S Ng, S Lim, ACN Sim, R Mangadu, A Lau, C Zhang, SB Martinez, A Chandramoh, UM Lim, SSW Ho, SC Chang, P Gopal, LZ Hong, A Schwaid, AZ Fernandis, A Loboda, C Li, U Phan, B Henry, AW Partridge
    Scientific Reports, 2022-08-18;12(1):14087.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Microglia Impairs Proliferation and Induces Senescence In-Vitro in NGF Releasing Cells Used in Encapsulated Cell Biodelivery for Alzheimer's Disease Therapy
    Authors: S Mitra, R Gera, J Sundheimer, M Lemee, LU Wahlberg, B Linderoth, M Eriksdotte, H Behbahani
    International Journal of Molecular Sciences, 2022-08-12;23(16):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  31. IFN-gamma stimulated murine and human neurons mount anti-parasitic defenses against the intracellular parasite Toxoplasma gondii
    Authors: S Chandrasek, JA Kochanowsk, EF Merritt, JS Lagas, A Swannigan, AA Koshy
    Nature Communications, 2022-08-08;13(1):4605.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Loss of immunity-related GTPase GM4951 leads to nonalcoholic fatty liver disease without obesity
    Authors: Z Zhang, Y Xun, S Rong, L Yan, JA SoRelle, X Li, M Tang, K Keller, S Ludwig, EMY Moresco, B Beutler
    Nature Communications, 2022-07-16;13(1):4136.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  33. IFNgamma-induced PD-L1 expression in ovarian cancer cells is regulated by JAK1, STAT1 and IRF1 signaling
    Authors: S Padmanabha, B Gaire, Y Zou, MM Uddin, I Vancurova
    Cellular Signalling, 2022-07-09;97(0):110400.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  34. In vitro assessment of the anti-inflammatory and skin-moisturizing effects of Filipendula palmata (Pall.) Maxim. On human keratinocytes and identification of its bioactive phytochemicals
    Authors: XJ Mi, JK Kim, S Lee, SK Moon, YJ Kim, H Kim
    Journal of ethnopharmacology, 2022-07-07;296(0):115523.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis
    Authors: MD Gundersen, KB Larsen, KM Johnsen, R Goll, J Florholmen, G Haraldsen
    Scientific Reports, 2022-07-07;12(1):11550.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  36. Long-term survival in non-human primates of stem cell-derived, MHC-unmatched corneal epithelial cell sheets
    Authors: Y Yoshinaga, T Soma, S Azuma, K Maruyama, Y Hashikawa, T Katayama, Y Sasamoto, H Takayanagi, N Hosen, T Shiina, K Ogasawara, R Hayashi, K Nishida
    Stem Cell Reports, 2022-06-23;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium
    Authors: E Iverson, K Griswold, D Song, TB Gagliardi, K Hamidzadeh, M Kesimer, S Sinha, M Perry, GA Duncan, MA Scull
    MBio, 2022-06-14;0(0):e0105522.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  38. IgM anti-ACE2 autoantibodies in severe COVID-19 activate complement and perturb vascular endothelial function
    Authors: L Casciola-R, DR Thiemann, F Andrade, MI Trejo-Zamb, EK Leonard, JB Spangler, NE Skinner, J Bailey, S Yegnasubra, R Wang, AM Vaghasia, A Gupta, AL Cox, SC Ray, RM Linville, Z Guo, PC Searson, CE Machamer, S Desiderio, LM Sauer, O Laeyendeck, BT Garibaldi, L Gao, M Damarla, PM Hassoun, JE Hooper, CA Mecoli, L Christophe, L Gutierrez-, Q Yang, D Hines, WA Clarke, RE Rothman, A Pekosz, KZ Fenstermac, Z Wang, SL Zeger, A Rosen
    JCI Insight, 2022-05-09;7(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Cooperative effects of RIG-I-like receptor signaling and IRF1 on DNA damage-induced cell death
    Authors: DY Zander, SS Burkart, S Wüst, VG Magalhães, M Binder
    Cell Death & Disease, 2022-04-18;13(4):364.
    Species: Human
    Sample Types: Whole Cell
    Applications: Bioassay
  40. Dendrobium nobile Lindley Administration Attenuates Atopic Dermatitis-like Lesions by Modulating Immune Cells
    Authors: S Hong, EY Kim, SE Lim, JH Kim, Y Sohn, HS Jung
    International Journal of Molecular Sciences, 2022-04-18;23(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Inhibiting Type I arginine methyltransferase activity promotes the T cell mediated antitumor immune response
    Authors: A Fedoriw, L Shi, S O'Brien, KN Smitheman, Y Wang, J Hou, C Sherk, S Rajapurkar, J Laraio, LJ Williams, C Xu, G Han, Q Feng, MT Bedford, L Wang, O Barbash, RG Kruger, P Hwu, HP Mohammad, W Peng
    Cancer Immunology Research, 2022-04-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells
    Authors: P Sekhri, DK Ledezma, A Shukla, EE Sweeney, R Fernandes
    Cancers, 2022-03-11;14(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  43. Interferon-gamma promotes monocyte-mediated lung injury during influenza infection
    Authors: T Schmit, K Guo, JK Tripathi, Z Wang, B McGregor, M Klomp, G Ambigapath, R Mathur, J Hur, M Pichichero, J Kolls, MN Khan
    Cell Reports, 2022-03-01;38(9):110456.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  44. MMP-10 from M1 macrophages promotes pulmonary vascular remodeling and pulmonary arterial hypertension
    Authors: PL Chi, CC Cheng, CC Hung, MT Wang, HY Liu, MW Ke, MC Shen, KC Lin, SH Kuo, PP Hsieh, SR Wann, WC Huang
    International journal of biological sciences, 2022-01-01;18(1):331-348.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  45. A Novel Kinase Inhibitor AX-0085 Inhibits Interferon-gamma-Mediated Induction of PD-L1 Expression and Promotes Immune Reaction to Lung Adenocarcinoma Cells
    Authors: J Kim, H Jang, GJ Lee, Y Hur, J Keum, JK Jo, SE Yun, SJ Park, YJ Park, MJ Choi, KS Kim, J Kim
    Cells, 2021-12-22;11(1):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  46. Inhibitor of growth protein 3 epigenetically silences endogenous retroviral elements and prevents innate immune activation
    Authors: Y Song, G Hou, J Diep, YS Ooi, NS Akopyants, SM Beverley, JE Carette, HB Greenberg, S Ding
    Nucleic Acids Research, 2021-12-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  47. SOX10 requirement for melanoma tumor growth is due, in part, to immune-mediated effects
    Authors: SR Rosenbaum, M Tiago, S Caksa, C Capparelli, TJ Purwin, G Kumar, M Glasheen, D Pomante, D Kotas, I Chervoneva, AE Aplin
    Cell Reports, 2021-12-07;37(10):110085.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Stress increases MHC-I expression in dopaminergic neurons and induces autoimmune activation in Parkinson's disease
    Authors: BY Wang, YY Ye, C Qian, HB Zhang, HX Mao, LP Yao, X Sun, GH Lu, SZ Zhang
    Neural regeneration research, 2021-12-01;16(12):2521-2527.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets
    Authors: A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial
    Cell Reports, 2021-11-23;37(8):110037.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  50. Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells
    Authors: CW Lee, YF Chen, AW Hsiao, AY Wang, OY Shen, BY Wang, LWC Ho, WT Lin, CHJ Choi, OK Lee
    Journal of advanced research, 2021-11-19;39(0):73-88.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  51. TM4SF5-dependent crosstalk between hepatocytes and macrophages to reprogram the inflammatory environment
    Authors: E Kim, H Um, J Park, JW Jung, JE Kim, H Lee, EA Shin, Y Pinanga, H Lee, SH Nam, JW Lee
    Cell Reports, 2021-11-16;37(7):110018.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Proteasome inhibitors restore the STAT1 pathway and enhance the expression of MHC class I on human colon cancer cells
    Authors: YH Liang, KH Chen, JH Tsai, YM Cheng, CC Lee, CH Kao, KY Chan, YT Chen, WL Hsu, KH Yeh
    Journal of Biomedical Science, 2021-11-10;28(1):75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-kappaB signaling
    Authors: C Xu, J Tang, Q Yang, H Zhao, Y Liu, J Cao, Y Zhou, X Chen, J Chen
    The Journal of Biological Chemistry, 2021-11-03;0(0):101380.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris
    Authors: S Shao, J Chen, WR Swindell, LC Tsoi, X Xing, F Ma, R Uppala, MK Sarkar, O Plazyo, AC Billi, R Wasikowski, KM Smith, P Honore, VE Scott, E Maverakis, JM Kahlenberg, G Wang, NL Ward, PW Harms, JE Gudjonsson
    JCI Insight, 2021-10-22;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Comparative Analysis of Six IRF Family Members in Alveolar Epithelial Cell-Intrinsic Antiviral Responses
    Authors: S Wüst, P Schad, S Burkart, M Binder
    Cells, 2021-09-30;10(10):.
    Species: Human
    Sample Types: Whole Cell
    Applications: Stimulation
  56. IFN-gamma Licensing Does Not Enhance the Reduced Immunomodulatory Potential and Migratory Ability of Differentiation-Induced Porcine Bone Marrow-Derived Mesenchymal Stem Cells in an In Vitro Xenogeneic Application
    Authors: HJ Lee, HD Kim, CH Jo, EY Bok, SB Kim, SL Lee, M Jang, SG Bae, SH Yun, SJ Kim, GJ Rho, WJ Lee
    BioMed Research International, 2021-09-04;2021(0):4604856.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Impact of Type 2 Diabetes Mellitus on the Immunoregulatory Characteristics of Adipose Tissue-Derived Mesenchymal Stem Cells
    Authors: N Abu-Shahba, M Mahmoud, AM El-Erian, MI Husseiny, G Nour-Eldee, I Helwa, K Amr, M ElHefnawi, AI Othman, SA Ibrahim, O Azmy
    The international journal of biochemistry & cell biology, 2021-08-26;0(0):106072.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Impaired immunomodulatory capacity in adipose tissue-derived mesenchymal stem/stromal cells isolated from obese patients
    Authors: XY Zhu, N Klomjit, SM Conley, MM Ostlie, KL Jordan, A Lerman, LO Lerman
    Journal of Cellular and Molecular Medicine, 2021-08-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  59. The effects of T-DXd on the expression of HLA class I and chemokines CXCL9/10/11 in HER2-overexpressing gastric cancer cells
    Authors: S Nakajima, K Mimura, T Matsumoto, AK Thar Min, M Ito, H Nakano, P Neupane, Y Kanke, H Okayama, M Saito, T Momma, Y Watanabe, H Hanayama, S Hayase, Z Saze, K Kono
    Scientific Reports, 2021-08-19;11(1):16891.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Hofbauer Cells Spread Listeria monocytogenes among Placental Cells and Undergo Pro-Inflammatory Reprogramming while Retaining Production of Tolerogenic Factors
    Authors: S Azari, LJ Johnson, A Webb, SM Kozlowski, X Zhang, K Rood, A Amer, S Seveau
    MBio, 2021-08-17;12(4):e0184921.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  61. IFITM proteins promote SARS-CoV-2 infection and are targets for virus inhibition in vitro
    Authors: C Prelli Boz, R Nchioua, M Volcic, L Koepke, J Krüger, D Schütz, S Heller, CM Stürzel, D Kmiec, C Conzelmann, J Müller, F Zech, E Braun, R Gro beta, L Wettstein, T Weil, J Wei beta, F Diofano, AA Rodríguez, S Wiese, D Sauter, J Münch, C Goffinet, A Catanese, M Schön, TM Boeckers, S Stenger, K Sato, S Just, A Kleger, KMJ Sparrer, F Kirchhoff
    Nature Communications, 2021-07-28;12(1):4584.
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  62. Mechanistic insight into bacterial entrapment by septin cage reconstitution
    Authors: D Lobato-Már, J Xu, GÖ Güler, A Ojiakor, M Pilhofer, S Mostowy
    Nature Communications, 2021-07-23;12(1):4511.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  63. The inflammatory regulation of TRPA1 expression in human A549 lung epithelial cells
    Authors: S Luostarine, M Hämäläinen, N Hatano, K Muraki, E Moilanen
    Pulmonary pharmacology & therapeutics, 2021-07-21;70(0):102059.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  64. FKBP3 Induces Human Immunodeficiency Virus Type 1 Latency by Recruiting Histone Deacetylase 1/2 to the Viral Long Terminal Repeat
    Authors: X Yang, X Zhao, Y Zhu, Y Shen, Y Wang, P Lu, Z Jiang, H Pan, J Yang, J Xun, L Zhao, J Wang, Z Liang, X Shen, Y Liang, Q Lin, H Liang, L Jin, D Zhang, J Liu, B Wang, S Jiang, J Xu, H Wu, H Lu, H Zhu
    MBio, 2021-07-20;0(0):e0079521.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Disrupting Mitochondrial Electron Transfer Chain Complex I Decreases Immune Checkpoints in Murine and Human Acute Myeloid Leukemic Cells
    Authors: R Luna-Yolba, J Marmoiton, V Gigo, X Marechal, E Boet, A Sahal, N Alet, I Abramovich, E Gottlieb, V Visentin, MR Paillasse, JE Sarry
    Cancers, 2021-07-13;13(14):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Oxidized-Desialylated Low-Density Lipoprotein Inhibits the Antitumor Functions of Lymphokine Activated Killer Cells
    Authors: JS Aguilar Dí, HL Glenn, M Knappenber, CR Borges
    Journal of Cancer, 2021-06-16;12(16):4993-5004.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA (Capture)
  67. Identification of genes modulated by interferon gamma in breast cancer cells
    Authors: AC Tecalco-Cr, M Macías-Sil, JO Ramírez-Ja, B Méndez-Amb
    Biochemistry and Biophysics Reports, 2021-06-16;27(0):101053.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  68. Skullcapflavone II Suppresses TNF-alpha/IFN-gamma-Induced TARC, MDC, and CTSS Production in HaCaT Cells
    Authors: H Lee, DH Lee, JH Oh, JH Chung
    International Journal of Molecular Sciences, 2021-06-16;22(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  69. STAT1 potentiates oxidative stress revealing a targetable vulnerability that increases phenformin efficacy in breast cancer
    Authors: SP Totten, YK Im, E Cepeda Cañ, O Najyb, A Nguyen, S Hébert, R Ahn, K Lewis, B Lebeau, R La Selva, V Sabourin, C Martínez, P Savage, H Kuasne, D Avizonis, N Santos Mar, C Chabot, A Aguilar-Ma, ML Goulet, M Dankner, M Witcher, K Petrecca, M Basik, M Pollak, I Topisirovi, R Lin, PM Siegel, CL Kleinman, M Park, J St-Pierre, J Ursini-Sie
    Nature Communications, 2021-06-03;12(1):3299.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  70. The discriminatory power of the T cell receptor
    Authors: J Pettmann, A Huhn, E Abu Shah, MA Kutuzov, DB Wilson, ML Dustin, SJ Davis, PA van der Me, O Dushek
    Elife, 2021-05-25;10(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  71. Proteoglycan 4 Modulates Osteogenic Smooth Muscle Cell Differentiation during Vascular Remodeling and Intimal Calcification
    Authors: T Seime, AC Akbulut, ML Liljeqvist, A Siika, H Jin, G Winski, RH van Gorp, E Karlöf, M Lengquist, AJ Buckler, M Kronqvist, OJ Waring, JHN Lindeman, EAL Biessen, L Maegdefess, A Razuvaev, LJ Schurgers, U Hedin, L Matic
    Cells, 2021-05-21;10(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Claudin-Low Breast Cancer Inflammatory Signatures Support Polarization of M1-Like Macrophages with Protumoral Activity
    Authors: MC Suárez-Arr, A Méndez-Ten, V Pérez-Kold, EM Fuentes-Pa
    Cancers, 2021-05-07;13(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Chemotherapy agents stimulate dendritic cells against human colon cancer cells through upregulation of the transporter associated with antigen processing
    Authors: YH Liang, JH Tsai, YM Cheng, KY Chan, WL Hsu, CC Lee, KH Chen, KH Yeh
    Scientific Reports, 2021-04-27;11(1):9080.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  74. The Conversion of Human Tissue-Like Inflammatory Monocytes Into Macrophages.
    Authors: Bsat M, Mehta H, Rubio M, Sarfati M
    Curr Protoc, 2021-03-01;1(3):e74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Opposing immune and genetic mechanisms shape oncogenic programs in synovial sarcoma
    Authors: L Jerby-Arno, C Neftel, ME Shore, HR Weisman, ND Mathewson, MJ McBride, B Haas, B Izar, A Volorio, G Boulay, L Cironi, AR Richman, LC Broye, JM Gurski, CC Luo, R Mylvaganam, L Nguyen, S Mei, JC Melms, C Georgescu, O Cohen, JE Buendia-Bu, A Segerstolp, M Sud, MS Cuoco, D Labes, S Gritsch, DR Zollinger, N Ortogero, JM Beechem, G Petur Niel, I Chebib, T Nguyen-Ngo, M Montemurro, GM Cote, E Choy, I Letovanec, S Cherix, N Wagle, PK Sorger, AB Haynes, JT Mullen, I Stamenkovi, MN Rivera, C Kadoch, KW Wucherpfen, O Rozenblatt, ML Suvà, N Riggi, A Regev
    Nature Medicine, 2021-01-25;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Tissue-specific endothelial cell heterogeneity contributes to unequal inflammatory responses
    Authors: H Gunawardan, T Romero, N Yao, S Heidt, A Mulder, DA Elashoff, NM Valenzuela
    Scientific Reports, 2021-01-21;11(1):1949.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  77. SHP2 blockade enhances anti-tumor immunity via tumor cell intrinsic and extrinsic mechanisms
    Authors: Y Wang, M Mohseni, A Grauel, JE Diez, W Guan, S Liang, JE Choi, M Pu, D Chen, T Laszewski, S Schwartz, J Gu, L Mansur, T Burks, L Brodeur, R Velazquez, S Kovats, B Pant, G Buruzula, E Deng, JT Chen, F Sari-Sarra, C Dornelas, M Varadaraja, H Yu, C Liu, J Lim, HX Hao, X Jiang, A Malamas, MJ LaMarche, FC Geyer, M McLaughlin, C Costa, J Wagner, D Ruddy, P Jayaraman, ND Kirkpatric, P Zhang, O Iartchouk, K Aardalen, V Cremasco, G Dranoff, JA Engelman, S Silver, H Wang, WD Hastings, S Goldoni
    Scientific Reports, 2021-01-14;11(1):1399.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes
    Authors: TM Garcia-Bat, ML Palma, RR Anderko, DC Hsu, J Ananworani, BT Korber, GD Gaiha, N Phanuphak, R Thomas, S Tovanabutr, BD Walker, JW Mellors, PA Piazza, E Kroon, SA Riddler, NL Michael, CR Rinaldo, RB Mailliard, I4C and RV
    EBioMedicine, 2021-01-12;63(0):103175.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Repurposing screen identifies Amlodipine as an inducer of PD-L1 degradation and antitumor immunity
    Authors: C Li, H Yao, H Wang, JY Fang, J Xu
    Oncogene, 2020-12-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  80. Interferon-gamma promotes iron export in human macrophages to limit intracellular bacterial replication
    Authors: R Abreu, L Essler, P Giri, F Quinn
    PLoS ONE, 2020-12-08;15(12):e0240949.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  81. M1 Macrophage-Derived Exosomal MicroRNA-326 Suppresses Hepatocellular Carcinoma Cell Progression Via Mediating NF-&kappaB Signaling Pathway
    Authors: ZZ Bai, HY Li, CH Li, CL Sheng, XN Zhao
    Nanoscale research letters, 2020-12-02;15(1):221.
    Species: Human
    Sample Types: Whole Cells
  82. 18F-FHBG PET-CT Reporter Gene Imaging of Adoptive CIK Cell Transfer Immunotherapy for Breast Cancer in a Mouse Model
    Authors: X Li, G Yin, W Ji, J Liu, Y Zhang, J Wang, X Zhu, L Zhu, D Dai, W Ma, W Xu
    Onco Targets Ther, 2020-11-13;13(0):11659-11668.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  83. Interferon-&gamma signaling synergizes with LRRK2 in neurons and microglia derived from human induced pluripotent stem cells
    Authors: V Panagiotak, D Ivanyuk, S De Cicco, W Haq, A Arsi?, C Yu, D Messelodi, M Oldrati, DC Schöndorf, MJ Perez, RP Cassatella, M Jakobi, N Schneiderh, T Gasser, I Niki?-Spie, M Deleidi
    Nat Commun, 2020-10-14;11(1):5163.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation
    Authors: EM Wilfong, R Croze, X Fang, M Schwede, E Niemi, GY López, JW Lee, MC Nakamura, MA Matthay
    PLoS ONE, 2020-10-06;15(10):e0240319.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  85. ISG15 Connects Autophagy and IFN-&gamma-Dependent Control of Toxoplasma gondii Infection in Human Cells
    Authors: J Bhushan, JB Radke, YC Perng, M Mcallaster, DJ Lenschow, HW Virgin, LD Sibley
    MBio, 2020-10-06;11(5):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  86. Mesenchymal stem/stromal cell quality control: validation of mixed lymphocyte reaction assay using flow cytometry according to ICH Q2(R1)
    Authors: T Nicotra, A Desnos, J Halimi, H Antonot, L Reppel, T Belmas, A Freton, F Stranieri, M Mebarki, J Larghero, A Cras, L Faivre
    Stem Cell Res Ther, 2020-10-01;11(1):426.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  87. Modeling COVID-19 with Human Pluripotent Stem Cell-Derived Cells Reveals Synergistic Effects of Anti-inflammatory Macrophages with ACE2 Inhibition Against SARS-CoV-2
    Authors: F Duan, L Guo, L Yang, Y Han, A Thakur, BE Nilsson-Pa, P Wang, Z Zhang, CY Ma, X Zhou, T Han, T Zhang, X Wang, D Xu, X Duan, J Xiang, HF Tse, C Liao, W Luo, FP Huang, YW Chen, T Evans, RE Schwartz, B tenOever, DD Ho, S Chen, Q Lian, HJ Chen
    Res Sq, 2020-09-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Androgen receptor signalling in macrophages promotes TREM-1-mediated prostate cancer cell line migration and invasion
    Authors: B Cioni, A Zaalberg, JR van Beijnu, MHM Melis, J van Burgst, MJ Muraro, E Hooijberg, D Peters, I Hofland, Y Lubeck, J de Jong, J Sanders, J Vivié, HG van der Po, JP de Boer, AW Griffioen, W Zwart, AM Bergman
    Nat Commun, 2020-09-09;11(1):4498.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Mimicry Embedding Facilitates Advanced Neural Network Training for Image-Based Pathogen Detection
    Authors: A Yakimovich, M Huttunen, J Samolej, B Clough, N Yoshida, S Mostowy, EM Frickel, J Mercer
    mSphere, 2020-09-09;5(5):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia
    Authors: S Kim, M Park, JY Kim, T Kim, JY Hwang, KS Ha, MH Won, S Ryoo, YG Kwon, YM Kim
    Cells, 2020-08-31;9(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Human CD8+ T Cells Exhibit a Shared Antigen Threshold for Different Effector Responses
    Authors: E Abu-Shah, N Trendel, P Kruger, J Nguyen, J Pettmann, M Kutuzov, O Dushek
    J. Immunol., 2020-08-17;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  92. Thrombomodulin facilitates peripheral nerve regeneration through regulating M1/M2 switching
    Authors: TC Huang, HL Wu, SH Chen, YT Wang, CC Wu
    J Neuroinflammation, 2020-08-14;17(1):240.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  93. Human GBP1 Differentially Targets Salmonella and Toxoplasma to License Recognition of Microbial Ligands and Caspase-Mediated Death
    Authors: D Fisch, B Clough, MC Domart, V Encheva, H Bando, AP Snijders, LM Collinson, M Yamamoto, AR Shenoy, EM Frickel
    Cell Rep, 2020-08-11;32(6):108008.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Oxidized Low-Density Lipoprotein Induces Macrophage Production of Prothrombotic Microparticles
    Authors: JF Marchini, A Manica, P Crestani, J Dutzmann, EJ Folco, H Weber, P Libby, K Croce
    J Am Heart Assoc, 2020-07-31;9(15):e015878.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Insights into the Mechanism of Action of Highly Diluted Biologics
    Authors: SA Tarasov, EA Gorbunov, ES Don, AG Emelyanova, AL Kovalchuk, N Yanamala, AS S Schleker, J Klein-Seet, R Groenestei, JP Tafani, P van der Me, OI Epstein
    J. Immunol., 2020-07-29;0(0):.
    Species: Human
    Sample Types: Protein
    Applications: Bioassay
  96. Effect of IFN-gamma on the kynurenine/tryptophan ratio in monolayer-cultured keratinocytes and a 3D reconstructed human epidermis model
    Authors: A Gustafsson, Z Prgomet, S Jankovskaj, T Ruzgas, J Engblom, L Ohlsson, A Gjörloff W
    J. Dermatol. Sci., 2020-07-17;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Modeling Type 1 Diabetes In�Vitro Using Human Pluripotent Stem Cells
    Authors: NC Leite, E Sintov, TB Meissner, MA Brehm, DL Greiner, DM Harlan, DA Melton
    Cell Rep, 2020-07-14;32(2):107894.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Inflammation Differentially Modulates the Biological Features of Adult Derived Human Liver Stem/Progenitor Cells
    Authors: H El-Kehdy, M Najar, J De Kock, DM Agha, V Rogiers, M Merimi, L Lagneaux, EM Sokal, M Najimi
    Cells, 2020-07-08;9(7):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  99. Mapping effector genes at lupus GWAS loci using promoter Capture-C in follicular helper T cells
    Authors: C Su, ME Johnson, A Torres, RM Thomas, E Manduchi, P Sharma, P Mehra, C Le Coz, ME Leonard, S Lu, KM Hodge, A Chesi, J Pippin, N Romberg, SFA Grant, AD Wells
    Nat Commun, 2020-07-03;11(1):3294.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  100. Glycosaminoglycans bind human IL-27 and regulate its activity
    Authors: MC Cavé, S Maillard, K Hildenbran, C Mamelonet, MJ Feige, O Devergne
    Eur. J. Immunol., 2020-07-02;0(0):.
    Species: Human
    Sample Types: Protein
    Applications: Bioassay
  101. T Cell-Intrinsic IRF5 Regulates T Cell Signaling, Migration, and Differentiation and Promotes Intestinal Inflammation
    Authors: J Yan, SP Pandey, BJ Barnes, JR Turner, C Abraham
    Cell Rep, 2020-06-30;31(13):107820.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  102. MLKL trafficking and accumulation at the plasma membrane control the kinetics and threshold for necroptosis
    Authors: AL Samson, Y Zhang, ND Geoghegan, XJ Gavin, KA Davies, MJ Mlodzianos, LW Whitehead, D Frank, SE Garnish, C Fitzgibbon, A Hempel, SN Young, AV Jacobsen, W Cawthorne, EJ Petrie, MC Faux, K Shield-Art, N Lalaoui, JM Hildebrand, J Silke, KL Rogers, G Lessene, ED Hawkins, JM Murphy
    Nat Commun, 2020-06-19;11(1):3151.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Targeting macrophage checkpoint inhibitor SIRPa for anticancer therapy
    Authors: J Liu, S Xavy, S Mihardja, S Chen, K Sompalli, D Feng, TS Choi, B Agoram, R Majeti, IL Weissman, JP Volkmer
    JCI Insight, 2020-06-18;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Immunity-and-matrix-regulatory cells derived from human embryonic stem cells safely and effectively treat mouse lung injury and fibrosis
    Authors: J Wu, D Song, Z Li, B Guo, Y Xiao, W Liu, L Liang, C Feng, T Gao, Y Chen, Y Li, Z Wang, J Wen, S Yang, P Liu, L Wang, Y Wang, L Peng, GN Stacey, Z Hu, G Feng, W Li, Y Huo, R Jin, N Shyh-Chang, Q Zhou, L Wang, B Hu, H Dai, J Hao
    Cell Res., 2020-06-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Resolvin D1 and D2 inhibit tumour growth and inflammation via modulating macrophage polarization
    Authors: K Shan, N Feng, J Cui, S Wang, H Qu, G Fu, J Li, H Chen, X Wang, R Wang, Y Qi, Z Gu, YQ Chen
    J. Cell. Mol. Med., 2020-05-29;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Diminished toll-like receptor response in febrile infection-related epilepsy syndrome (FIRES)
    Authors: MY Hsieh, JJ Lin, SH Hsia, JL Huang, KW Yeh, KW Chang, WI Lee
    Biomed J, 2020-05-29;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. Mapping DNA interaction landscapes in psoriasis susceptibility loci highlights KLF4 as a target gene in 9q31
    Authors: H Ray-Jones, K Duffus, A McGovern, P Martin, C Shi, J Hankinson, O Gough, A Yarwood, AP Morris, A Adamson, C Taylor, J Ding, VP Gaddi, Y Fu, P Gaffney, G Orozco, RB Warren, S Eyre
    BMC Biol., 2020-05-04;18(1):47.
    Species: Human
    Sample Types:
    Applications: Cell Culture
  108. Increase in Efficacy of Checkpoint Inhibition by Cytokine-Induced-Killer Cells as a Combination Immunotherapy for Renal Cancer
    Authors: MN Dehno, Y Li, H Weiher, IGH Schmidt-Wo
    Int J Mol Sci, 2020-04-27;21(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  109. RIG-I-like receptor activation drives type I IFN and antiviral signaling to limit�Hantaan orthohantavirus replication
    Authors: AM Kell, EA Hemann, JB Turnbull, M Gale
    PLoS Pathog., 2020-04-24;16(4):e1008483.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  110. Macrophage M2 polarization induced by exosomes from adipose-derived stem cells contributes to the exosomal proangiogenic effect on mouse ischemic hindlimb
    Authors: D Zhu, TK Johnson, Y Wang, M Thomas, K Huynh, Q Yang, VC Bond, YE Chen, D Liu
    Stem Cell Res Ther, 2020-04-22;11(1):162.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  111. M1-like macrophages are potent producers of anti-viral interferons and M1-associated marker-positive lung macrophages are decreased during rhinovirus-induced asthma exacerbations
    Authors: A Nikonova, M Khaitov, DJ Jackson, S Traub, MB Trujillo-T, DA Kudlay, AS Dvornikov, A Del-Rosari, R Valenta, LA Stanciu, R Khaitov, SL Johnston
    EBioMedicine, 2020-04-09;54(0):102734.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  112. HDAC Inhibitor, CG-745, Enhances the Anti-Cancer Effect of Anti-PD-1 Immune Checkpoint Inhibitor by Modulation of the Immune Microenvironment
    Authors: YD Kim, SM Park, HC Ha, AR Lee, H Won, H Cha, S Cho, JM Cho
    J Cancer, 2020-04-06;11(14):4059-4072.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Class IIa Histone Deacetylases Drive Toll-like Receptor-Inducible Glycolysis and Macrophage Inflammatory Responses via Pyruvate Kinase M2
    Authors: K Das Gupta, MR Shakespear, JEB Curson, AMV Murthy, A Iyer, MP Hodson, D Ramnath, VA Tillu, JB von Pein, RC Reid, K Tunny, DM Hohenhaus, SV Moradi, GM Kelly, T Kobayashi, JH Gunter, AJ Stevenson, W Xu, L Luo, A Jones, WA Johnston, A Blumenthal, K Alexandrov, BM Collins, JL Stow, DP Fairlie, MJ Sweet
    Cell Rep, 2020-02-25;30(8):2712-2728.e8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  114. The anti-inflammatory potential of cefazolin as common gamma chain cytokine inhibitor
    Authors: B ?y?y?ska-G, B Trzaskowsk, M Dutkiewicz, O Zegrocka-S, M Machci?ska, K Bocian, M Kowalewska, K Koziak
    Sci Rep, 2020-02-19;10(1):2886.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  115. Anti-PD-1 antibody decreases tumour-infiltrating regulatory T cells
    Authors: K Yoshida, M Okamoto, J Sasaki, C Kuroda, H Ishida, K Ueda, H Ideta, T Kamanaka, A Sobajima, T Takizawa, M Tanaka, K Aoki, T Uemura, H Kato, H Haniu, N Saito
    BMC Cancer, 2020-01-08;20(1):25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  116. Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum
    Authors: A Stumpf, T Brandstett, J Hübner, J Rühe
    PLoS ONE, 2019-12-02;14(12):e0225525.
    Species: Human
    Sample Types: Serum
    Applications: ELISA Standard
  117. Mitochondrial mass governs the extent of human T cell senescence
    Authors: LA Callender, EC Carroll, EA Bober, AN Akbar, E Solito, SM Henson
    Aging Cell, 2019-12-02;0(0):e13067.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients
    Authors: D Deli?, K Wolk, R Schmid, O Gabrielyan, D Christou, K Rieber, M Rolser, I Jakob, F Wiech, M Griesser, C Wohnhaas, G Kokolakis, E Witte-Händ, P Baum, R Sabat
    J. Dermatol. Sci., 2019-11-30;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Immunomodulatory properties of photopolymerizable fucoidan and carrageenans
    Authors: ML Amin, D Mawad, S Dokos, P Koshy, PJ Martens, CC Sorrell
    Carbohydr Polym, 2019-11-28;230(0):115691.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  120. Mini tryptophanyl-tRNA synthetase is required for a synthetic phenotype in vascular smooth muscle cells induced by IFN-?-mediated beta2-adrenoceptor signaling
    Authors: E Biros, CS Moran
    Cytokine, 2019-11-28;127(0):154940.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  121. Pro-inflammatory monocyte profile in patients with major depressive disorder and suicide behaviour and how ketamine induces anti-inflammatory M2 macrophages by NMDAR and mTOR
    Authors: W Nowak, LN Grendas, LM Sanmarco, IG Estecho, ÁR Arena, N Eberhardt, DE Rodante, MP Aoki, FM Daray, EA Carrera Si, AE Errasti
    EBioMedicine, 2019-11-18;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  122. High glucose environment induces M1 macrophage polarization that impairs keratinocyte migration via TNF-alpha: An important mechanism to delay the diabetic wound healing
    Authors: SM Huang, CS Wu, MH Chiu, CH Wu, YT Chang, GS Chen, CE Lan
    J. Dermatol. Sci., 2019-11-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  123. Complex alternative splicing of human Endonuclease V mRNA, but evidence for only a single protein isoform
    Authors: N Berges, MS Nawaz, T Børresdatt, L Hagen, M Bjørås, JK Laerdahl, I Alseth
    PLoS ONE, 2019-11-08;14(11):e0225081.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  124. Dynamic lineage priming is driven via direct enhancer regulation by ERK
    Authors: WB Hamilton, Y Mosesson, RS Monteiro, KB Emdal, TE Knudsen, C Francavill, N Barkai, JV Olsen, JM Brickman
    Nature, 2019-11-06;575(7782):355-360.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  125. TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation
    Authors: KA Jha, M Pentecost, R Lenin, J Gentry, L Klaic, N Del Mar, A Reiner, CH Yang, LM Pfeffer, N Sohl, R Gangaraju
    Stem Cell Res Ther, 2019-11-05;10(1):318.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  126. Extracellular Vesicles Shedding Promotes Melanoma Growth in Response to Chemotherapy
    Authors: LNS Andrade, AH Otake, SGB Cardim, FI da Silva, MM Ikoma Saka, TK Furuya, M Uno, FS Pasini, R Chammas
    Sci Rep, 2019-10-09;9(1):14482.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  127. Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress
    Authors: C Merriman, D Fu
    J. Biol. Chem., 2019-10-07;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. IL-4 and IL-17A Cooperatively Promote Hydrogen Peroxide Production, Oxidative DNA Damage, and Upregulation of Dual Oxidase 2 in Human Colon and Pancreatic Cancer Cells
    Authors: Y Wu, MM Konaté, J Lu, H Makhlouf, R Chuaqui, S Antony, JL Meitzler, MJ Difilippan, H Liu, A Juhasz, G Jiang, I Dahan, K Roy, JH Doroshow
    J. Immunol., 2019-09-23;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Integrated Transcriptomic, Phenotypic, and Functional Study Reveals Tissue-Specific Immune Properties of Mesenchymal Stromal Cells
    Authors: C Ménard, J Dulong, D Roulois, B Hébraud, L Verdière, C Pangault, V Sibut, I Bezier, N Bescher, C Monvoisin, M Gadelorge, N Bertheuil, E Flécher, L Casteilla, P Collas, L Sensebé, P Bourin, N Espagnolle, K Tarte
    Stem Cells, 2019-09-10;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Boiling Histotripsy-induced Partial Mechanical Ablation Modulates Tumour Microenvironment by Promoting Immunogenic Cell Death of Cancers
    Authors: KJ Pahk, CH Shin, IY Bae, Y Yang, SH Kim, K Pahk, H Kim, SJ Oh
    Sci Rep, 2019-06-21;9(1):9050.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  131. LIF regulates CXCL9 in tumor-associated macrophages and prevents CD8+ T cell tumor-infiltration impairing anti-PD1 therapy
    Authors: M Pascual-Ga, E Bonfill-Te, E Planas-Rig, C Rubio-Pere, R Iurlaro, A Arias, I Cuartas, A Sala-Hojma, L Escudero, F Martínez-R, I Huber-Ruan, P Nuciforo, L Pedrosa, C Marques, I Braña, E Garralda, M Vieito, M Squatrito, E Pineda, F Graus, C Espejo, J Sahuquillo, J Tabernero, J Seoane
    Nat Commun, 2019-06-11;10(1):2416.
    Species: Human
    Sample Types: Organoid
    Applications: Bioassay
  132. Inhibitory Effects of a Novel Chrysin-Derivative, CPD 6, on Acute and Chronic Skin Inflammation
    Authors: CH Yu, B Suh, I Shin, EH Kim, D Kim, YJ Shin, SY Chang, SH Baek, H Kim, ON Bae
    Int J Mol Sci, 2019-05-28;20(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist
    Authors: S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett
    Stem Cells, 2019-05-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  134. Differential modulation of CXCL8 versus CXCL10, by cytokines, PPAR-gamma, or PPAR-alpha agonists, in primary cells from Graves' disease and ophthalmopathy
    Authors: SM Ferrari, F Ragusa, SR Paparo, F Nasini, M Nardi, SS Franceschi, P Fallahi, A Antonelli
    Autoimmun Rev, 2019-05-04;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  135. DNA from virulent M. tuberculosis induces TNF-? production and autophagy in M1 polarized macrophages
    Authors: A Ruiz, S Guzmán-Bel, LE Carreto-Bi, Y Gonzalez, E Juárez
    Microb. Pathog., 2019-05-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Autophagy links antimicrobial activity with antigen presentation in Langerhans cells
    Authors: AT Dang, RM Teles, PT Liu, A Choi, A Legaspi, EN Sarno, MT Ochoa, K Parvatiyar, G Cheng, M Gilliet, BR Bloom, RL Modlin
    JCI Insight, 2019-04-18;4(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  137. microRNA-148a-3p regulates immunosuppression in DNA mismatch repair-deficient colorectal cancer by targeting PD-L1
    Authors: M Ashizawa, H Okayama, T Ishigame, AK Thar Min, K Saito, D Ujiie, Y Murakami, T Kikuchi, Y Nakayama, M Noda, T Tada, H Endo, S Fujita, W Sakamoto, M Saito, Z Saze, T Momma, S Ohki, K Mimura, K Kono
    Mol. Cancer Res., 2019-03-14;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  138. APOBEC Mutagenesis and Copy-Number Alterations Are Drivers of Proteogenomic Tumor Evolution and Heterogeneity in Metastatic Thoracic Tumors
    Authors: N Roper, S Gao, TK Maity, AR Banday, X Zhang, A Venugopala, CM Cultraro, R Patidar, S Sindiri, AL Brown, A Goncearenc, AR Panchenko, R Biswas, A Thomas, A Rajan, CA Carter, DE Kleiner, SM Hewitt, J Khan, L Prokunina-, U Guha
    Cell Rep, 2019-03-05;26(10):2651-2666.e6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  139. Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells
    Authors: M Kita, Y Ano, A Inoue, J Aoki
    Sci Rep, 2019-02-28;9(1):3135.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  140. hCMV-Mediated Immune Escape Mechanisms Favor Pathogen Growth and Disturb the Immune Privilege of the Eye
    Authors: K Spekker-Bo, CM Ufermann, M Maywald, A Zimmermann, A Domröse, C Woite, W Däubener, SK Eller
    Int J Mol Sci, 2019-02-16;20(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  141. Preexisting Virus-Specific T Lymphocytes-Mediated Enhancement of Adenovirus Infections to Human Blood CD14+ Cells
    Authors: F Feng, J Zhao, P Li, R Li, L Chen, C Sun
    Viruses, 2019-02-13;11(2):.
    Species: Human
    Sample Types:
    Applications: Bioassay
  142. Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis
    Authors: JC de Quaglia, AM Della Cole, TP Gardizani, GG Romagnoli, R Kaneno, LA Dias-Melic
    J Immunol Res, 2019-02-06;2019(0):1529189.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Differential expression and regulation of the non-integrin 37/67-kDa laminin receptor on peripheral blood leukocytes of healthy individuals and patients with rheumatoid arthritis
    Authors: BA Kane, H An, P Rajasekari, HP McNeil, K Bryant, N Tedla
    Sci Rep, 2019-02-04;9(1):1149.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  144. CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS
    Authors: T Karnezis, R Farnsworth, NC Harris, SP Williams, C Caesar, DJ Byrne, P Herle, ML Macheda, R Shayan, YF Zhang, S Yazar, SJ Takouridis, C Gerard, S Fox, MG Achen, SA Stacker
    Cancer Res., 2019-02-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  145. Prioritizing Crohn's disease genes by integrating association signals with gene expression implicates monocyte subsets
    Authors: K Gettler, M Giri, E Kenigsberg, J Martin, LS Chuang, NY Hsu, LA Denson, JS Hyams, A Griffiths, JD Noe, WV Crandall, DR Mack, R Kellermaye, C Abraham, G Hoffman, S Kugathasan, JH Cho
    Genes Immun., 2019-01-29;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  146. IFN-? and IL-17A differentially influence the response of human macrophages and neutrophils to Pseudomonas aeruginosa infection
    Authors: S Muntaka, Y Almuhanna, D Jackson, S Singh, A Afryie-Asa, M Cámara, L Martínez-P
    Infect. Immun., 2019-01-24;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  147. Anti-Allergic and Anti-Inflammatory Effects of Kuwanon G and Morusin on MC/9 Mast Cells and HaCaT Keratinocytes
    Authors: SE Jin, H Ha, HK Shin, CS Seo
    Molecules, 2019-01-11;24(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Total HLA Class I Antigen Loss with the Downregulation of Antigen-Processing Machinery Components in Two Newly Established Sarcomatoid Hepatocellular Carcinoma Cell Lines
    Authors: WY Lei, SC Hsiung, SH Wen, CH Hsieh, CL Chen, CG Wallace, CC Chang, SK Liao
    J Immunol Res, 2018-12-16;2018(0):8363265.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Myeloid-Derived Suppressor Cells Produce IL-10 to Elicit DNMT3b-Dependent IRF8 Silencing to Promote Colitis-Associated Colon Tumorigenesis
    Authors: ML Ibrahim, JD Klement, C Lu, PS Redd, W Xiao, D Yang, DD Browning, NM Savage, PJ Buckhaults, HC Morse, K Liu
    Cell Rep, 2018-12-11;25(11):3036-3046.e6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  150. Non-muscle myosin IIA is post-translationally modified by interferon-stimulated gene 15 in breast cancer cells
    Authors: E Cruz-Ramos, M Macías-Sil, A Sandoval-H, AC Tecalco-Cr
    Int. J. Biochem. Cell Biol., 2018-12-05;107(0):14-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  151. Guanylate-Binding Protein 1 Promotes Migration and Invasion of Human Periodontal Ligament Stem Cells
    Authors: S Bai, T Chen, X Deng
    Stem Cells Int, 2018-11-28;2018(0):6082956.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Interplay between interferon-stimulated gene 15/ISGylation and interferon gamma signaling in breast cancer cells
    Authors: AC Tecalco-Cr, CC Cortés-Gon, E Cruz-Ramos, JO Ramírez Ja, AK Romero-Man, M Sosa-Garro
    Cell. Signal., 2018-11-27;54(0):91-101.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence
    Authors: M Rentschler, Y Chen, J Pahl, L Soria-Mart, H Braumüller, E Brenner, O Bischof, M Röcken, T Wieder
    Cell. Physiol. Biochem., 2018-11-26;51(3):1103-1118.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Detailed Characterization of Early HIV-1 Replication Dynamics in Primary Human Macrophages
    Authors: DA Bejarano, MC Puertas, K Börner, J Martinez-P, B Müller, HG Kräusslich
    Viruses, 2018-11-10;10(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Attenuation of CD47-SIRP? Signal in Cholangiocarcinoma Potentiates Tumor-Associated Macrophage-Mediated Phagocytosis and Suppresses Intrahepatic Metastasis
    Authors: K Vaeteewoot, R Kariya, P Pothipan, S Fujikawa, C Pairojkul, S Waraasawap, K Kuwahara, C Wongkham, S Wongkham, S Okada
    Transl Oncol, 2018-11-09;12(2):217-225.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  156. VISTA expressed in tumour cells regulates T cell function
    Authors: K Mulati, J Hamanishi, N Matsumura, K Chamoto, N Mise, K Abiko, T Baba, K Yamaguchi, N Horikawa, R Murakami, M Taki, K Budiman, X Zeng, Y Hosoe, M Azuma, I Konishi, M Mandai
    Br. J. Cancer, 2018-11-09;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Status of programmed death-ligand 1 expression in sarcomas
    Authors: HK Park, M Kim, M Sung, SE Lee, YJ Kim, YL Choi
    J Transl Med, 2018-11-06;16(1):303.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Exosomes released from tumor-associated macrophages transfer miRNAs that induce a Treg/Th17 cell imbalance in epithelial ovarian cancer
    Authors: J Zhou, X Li, X Wu, T Zhang, Q Zhu, X Wang, H Wang, K Wang, Y Lin, X Wang
    Cancer Immunol Res, 2018-11-05;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Functionalization-dependent effects of cellulose nanofibrils on tolerogenic mechanisms of human dendritic cells
    Authors: S Tomi?, N Ili?, V Kokol, A Gruden-Mov, D Mihajlovi?, M Beki?, L Sofroni?-M, M ?oli?, D Vu?evi?
    Int J Nanomedicine, 2018-10-31;13(0):6941-6960.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  160. IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment
    Authors: L Mercurio, M Morelli, C Scarponi, EZ Eisenmesse, N Doti, G Pagnanelli, E Gubinelli, C Mazzanti, A Cavani, M Ruvo, CA Dinarello, C Albanesi, S Madonna
    Cell Death Dis, 2018-10-30;9(11):1104.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Decreased allergy incidence in children supplemented with E. coli O83:K24:H31 and its possible modes of action
    Authors: J Hrdý, K Vlasáková, V ?erný, L Súkeníková, O Novotná, P Petrásková, K Boráková, R Lodinová-Ž, L Kolá?ová, L Prokešová
    Eur. J. Immunol., 2018-10-21;0(0):.
    Species: Human
    Sample Types: Plasma
  162. Co-culture of dendritic cells and cytokine-induced killer cells effectively suppresses liver cancer stem cell growth by inhibiting pathways in the immune system
    Authors: T Yang, W Zhang, L Wang, C Xiao, L Wang, Y Gong, D Huang, B Guo, Q Li, Y Xiang, Y Nan
    BMC Cancer, 2018-10-16;18(1):984.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  163. INF-?: A new spotlight in innate immunity against influenza virus infection
    Authors: Y Sun, J Jiang, P Tien, W Liu, J Li
    Protein Cell, 2018-10-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  164. Clearance of senescent glial cells prevents tau-dependent pathology and cognitive decline
    Authors: TJ Bussian, A Aziz, CF Meyer, BL Swenson, JM van Deurse, DJ Baker
    Nature, 2018-09-19;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  165. Prolonging culture of primary human keratinocytes isolated from suction blisters with the Rho kinase inhibitor Y-27632
    Authors: ED Anderson, I Sastalla, NJ Earland, M Mahnaz, IN Moore, F Otaizo-Car, TG Myers, CA Myles, SK Datta, IA Myles
    PLoS ONE, 2018-09-12;13(9):e0198862.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Interferon-gamma inhibits seminal plasma induction of colony stimulating factor 2 in mouse and human reproductive tract epithelial cells
    Authors: DJ Sharkey, DJ Glynn, JE Schjenken, KP Tremellen, SA Robertson
    Biol. Reprod., 2018-09-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  167. The proto-oncogene Bcl3 induces immune checkpoint PD-L1 expression, mediating proliferation of ovarian cancer cells
    Authors: Y Zou, MM Uddin, S Padmanabha, Y Zhu, P Bu, A Vancura, I Vancurova
    J. Biol. Chem., 2018-08-22;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Interleukin 4 is inactivated via selective disulfide-bond reduction by extracellular thioredoxin
    Authors: NM Plugis, N Weng, Q Zhao, BA Palanski, HT Maecker, A Habtezion, C Khosla
    Proc. Natl. Acad. Sci. U.S.A., 2018-08-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  169. ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes
    Authors: SL Figenschau, E Knutsen, I Urbarova, C Fenton, B Elston, M Perander, ES Mortensen, KA Fenton
    Sci Rep, 2018-08-06;8(1):11720.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-?, IL-1?, and IFN-?
    Authors: M Schwede, EM Wilfong, RL Zemans, PJ Lee, C Dos Santos, X Fang, MA Matthay
    Physiol Rep, 2018-08-01;6(16):e13831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  171. USP17 mediates macrophage-promoted inflammation and stemness in lung cancer cells by regulating TRAF2/TRAF3 complex formation
    Authors: CH Lu, DW Yeh, CY Lai, YL Liu, LR Huang, AY Lee, SC Jin, TH Chuang
    Oncogene, 2018-07-23;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Tumor innate immunity primed by specific interferon-stimulated endogenous retroviruses
    Authors: I Cañadas, R Thummalapa, JW Kim, S Kitajima, RW Jenkins, CL Christense, M Campisi, Y Kuang, Y Zhang, E Gjini, G Zhang, T Tian, DR Sen, D Miao, Y Imamura, T Thai, B Piel, H Terai, AR Aref, T Hagan, S Koyama, M Watanabe, H Baba, AE Adeni, CA Lydon, P Tamayo, Z Wei, M Herlyn, TU Barbie, R Uppaluri, LM Sholl, E Sicinska, J Sands, S Rodig, KK Wong, CP Paweletz, H Watanabe, DA Barbie
    Nat. Med., 2018-07-23;0(0):.
    Species: Human
    Sample Types: Transfected Whole Cells
    Applications: Bioassay
  173. Differential Gene Expression Profile of Human Neutrophils Cultured with Plasmodium falciparum-Parasitized Erythrocytes
    Authors: MA Terkawi, R Takano, K Kato
    J Immunol Res, 2018-07-05;2018(0):6709424.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  174. Proton irradiation orchestrates macrophage reprogramming through NF?B signaling
    Authors: G Genard, AC Wera, C Huart, B Le Calve, S Penninckx, A Fattacciol, T Tabarrant, C Demazy, N Ninane, AC Heuskin, S Lucas, C Michiels
    Cell Death Dis, 2018-06-27;9(7):728.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  175. Intratumoral delivery of an adenoviral vector carrying the SOCS-1 gene enhances T cell-mediated anti-tumor immunity by suppressing PD-L1
    Authors: S Nakagawa, S Serada, R Kakubari, K Hiramatsu, T Sugase, S Matsuzaki, S Matsuzaki, Y Ueda, K Yoshino, T Ohkawara, M Fujimoto, T Kishimoto, T Kimura, T Naka
    Mol. Cancer Ther., 2018-06-11;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  176. Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation
    Authors: JA Marwick, R Mills, O Kay, K Michail, J Stephen, AG Rossi, I Dransfield, N Hirani
    Cell Death Dis, 2018-06-04;9(6):665.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Interferon-gamma drives programmed death-ligand 1 expression on islet ? cells to limit T cell function during autoimmune diabetes
    Authors: KC Osum, AL Burrack, T Martinov, NL Sahli, JS Mitchell, CG Tucker, KE Pauken, K Papas, B Appakalai, JA Spanier, BT Fife
    Sci Rep, 2018-05-29;8(1):8295.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Unique and shared inflammatory profiles of human brain endothelia and pericytes
    Authors: LCD Smyth, J Rustenhove, TI Park, P Schweder, D Jansson, PA Heppner, SJ O'Carroll, EW Mee, RLM Faull, M Curtis, M Dragunow
    J Neuroinflammation, 2018-05-11;15(1):138.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  179. slan+ monocytes and macrophages mediate CD20-dependent B cell lymphoma elimination via ADCC and ADCP
    Authors: W Vermi, A Micheletti, G Finotti, C Tecchio, F Calzetti, S Costa, M Bugatti, S Calza, C Agostinell, S Pileri, P Balzarini, A Tucci, G Rossi, L Furlani, G Todeschini, A Zamò, F Facchetti, L Lorenzi, S Lonardi, MA Cassatella
    Cancer Res., 2018-05-10;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Antimycobacterial effect of IFNG (interferon gamma)-induced autophagy is dependent on the HMOX1 (heme oxygenase 1)-mediated increase in the intracellular calcium levels and modulation of PPP3/calcineurin-TFEB (transcription factor EB) axis
    Authors: N Singh, P Kansal, Z Ahmad, N Baid, H Kushwaha, N Khatri, A Kumar
    Autophagy, 2018-05-10;0(0):1-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli
    Authors: AE Dodi, IO Ajayi, C Chang, M Beard, SL Ashley, SK Huang, VJ Thannickal, DJ Tschumperl, TH Sisson, JC Horowitz
    Respir. Res., 2018-05-10;19(1):91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Metabolic systems analysis of LPS induced endothelial dysfunction applied to sepsis patient stratification
    Authors: S McGarrity, Ó Anuforo, H Halldórsso, A Bergmann, S Halldórsso, S Palsson, HH Henriksen, PI Johansson, Ó Rolfsson
    Sci Rep, 2018-05-01;8(1):6811.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Class 3 semaphorins modulate the invasive capacity of rheumatoid arthritis fibroblast-like synoviocytes
    Authors: MW Tang, B Malvar Fer, SP Newsom, JD van Buul, TRDJ Radstake, DL Baeten, PP Tak, KA Reedquist, S García
    Rheumatology (Oxford), 2018-05-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Differentiation, Differentiation
  184. Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms
    Authors: E Vorkapic, A Kunath, D Wågsäter
    Mol Med Rep, 2018-04-27;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Effect of colorectal cancer-derived extracellular vesicles on the immunophenotype and cytokine secretion profile of monocytes and macrophages
    Authors: I Pop?na, A ?bols, L Saul?te, K Pleiko, E Zandberga, K J?kabsons, E Endzeli?š, A Llorente, A Lin?, U Rieksti?a
    Cell Commun. Signal, 2018-04-24;16(1):17.
    Species: Human
    Sample Types: Whole Cells
    Applications: Differentiation, Differentiation
  186. The Absence of Indoleamine 2,3-Dioxygenase Inhibits Retinal Capillary Degeneration in Diabetic Mice
    Authors: RB Nahomi, S Sampathkum, AM Myers, L Elghazi, DG Smith, J Tang, CA Lee, TS Kern, RH Nagaraj, PE Fort
    Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):2042-2053.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  187. High-Mobility Group Box 1 in Dry Eye Inflammation
    Authors: C Lema, RY Reins, RL Redfern
    Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):1741-1750.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Natural Killer Cell Inhibition by HLA-E Molecules on Induced Pluripotent Stem Cell-Derived Retinal Pigment Epithelial Cells
    Authors: S Sugita, K Makabe, Y Iwasaki, S Fujii, M Takahashi
    Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):1719-1731.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Carcinoembryonic antigen as a marker of radioresistance in colorectal cancer: a potential role of macrophages
    Authors: EY Huang, JC Chang, HH Chen, CY Hsu, HC Hsu, KL Wu
    BMC Cancer, 2018-03-27;18(1):321.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus
    Authors: D Sireesh, U Dhamodhara, K Ezhilarasi, V Vijay, KM Ramkumar
    Sci Rep, 2018-03-23;8(1):5126.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  191. The RNA-binding protein MEX3B mediates resistance to cancer immunotherapy by downregulating HLA-A�expression
    Authors: L Huang, S Malu, JA McKenzie, MC Andrews, AH Talukder, T Tieu, TV Karpinets, C Haymaker, MA Forget, LJ Williams, Z Wang, R Mbofung, ZQ Wang, RE Davis, RS Lo, JA Wargo, MA Davies, C Bernatchez, TP Heffernan, RN Amaria, A Korkut, W Peng, J Roszik, G Lizee, SE Woodman, P Hwu
    Clin. Cancer Res., 2018-03-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  192. The PI3K?-Selective Inhibitor Idelalisib Minimally Interferes with Immune Effector Function Mediated by Rituximab or Obinutuzumab and Significantly Augments B Cell Depletion In Vivo
    Authors: A Palazzo, S Herter, L Grosmaire, R Jones, CR Frey, F Limani, M Bacac, P Umana, RJ Oldham, MJE Marshall, KL Cox, AH Turaj, MS Cragg, C Klein, MJ Carter, S Tannheimer
    J. Immunol., 2018-02-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes
    Authors: AJ Lakhter, RE Pratt, RE Moore, KK Doucette, BF Maier, LA DiMeglio, EK Sims
    Diabetologia, 2018-02-14;0(0):.
    Species: Human, Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  194. Changes in the Anti-Allergic Activities of Sesame by Bioconversion
    Authors: TD Jung, SI Choi, SH Choi, BY Cho, WS Sim, SJ Lee, SJ Park, DB Kim, YC Kim, JH Lee, OH Lee
    Nutrients, 2018-02-14;10(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  195. Pathogen recognition by NK cells amplifies the pro-inflammatory cytokine production of monocyte-derived DC via IFN-?
    Authors: T Oth, THPM Habets, WTV Germeraad, MI Zonneveld, GMJ Bos, J Vanderloch
    BMC Immunol., 2018-02-13;19(1):8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  196. Eradication of Triple-Negative Breast Cancer Cells by Targeting Glycosylated PD-L1
    Authors: CW Li, SO Lim, EM Chung, YS Kim, AH Park, J Yao, JH Cha, W Xia, LC Chan, T Kim, SS Chang, HH Lee, CK Chou, YL Liu, HC Yeh, EP Perillo, AK Dunn, CW Kuo, KH Khoo, JL Hsu, Y Wu, JM Hsu, H Yamaguchi, TH Huang, AA Sahin, GN Hortobagyi, SS Yoo, MC Hung
    Cancer Cell, 2018-02-12;33(2):187-201.e10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Virus-like infection induces human ? cell dedifferentiation
    Authors: M Oshima, KP Knoch, M Diedisheim, A Petzold, P Cattan, M Bugliani, P Marchetti, P Choudhary, GC Huang, SR Bornstein, M Solimena, O Albagli-Cu, R Scharfmann
    JCI Insight, 2018-02-08;3(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  198. MicroRNA-374b inhibits liver cancer progression via down regulating programmed cell death-1 expression on cytokine-induced killer cells
    Authors: F Huang, B Wang, J Zeng, S Sang, J Lei, Y Lu
    Oncol Lett, 2018-02-05;15(4):4797-4804.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Decreased RNF41 expression leads to insulin resistance in skeletal muscle of obese women
    Authors: C Breuker, C Amouzou, O Fabre, K Lambert, P Seyer, A Bourret, T Salehzada, J Mercier, A Sultan, C Bisbal
    Metab. Clin. Exp., 2018-02-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  200. RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature
    Authors: WR Swindell, MA Beamer, MK Sarkar, S Loftus, J Fullmer, X Xing, NL Ward, LC Tsoi, MJ Kahlenberg, Y Liang, JE Gudjonsson
    Front Immunol, 2018-01-29;9(0):80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  201. Trichinella spiralis Excretory-Secretory Products Induce Tolerogenic Properties in Human Dendritic CellsviaToll-Like Receptors 2 and 4
    Authors: N Ilic, A Gruden-Mov, J Cvetkovic, S Tomic, DB Vucevic, C Aranzamend, M Colic, E Pinelli, L Sofronic-M
    Front Immunol, 2018-01-24;9(0):11.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  202. The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock
    Authors: TA Nakada, P Wacharasin, JA Russell, JH Boyd, E Nakada, SA Thair, T Shimada, KR Walley
    J Innate Immun, 2018-01-16;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes enhances the killing effect of cytotoxic T lymphocytes on tumor stem-like cells derived from cisplatin-resistant lung cancer cells
    Authors: X Zhang, Y Zhang, J Xu, H Wang, X Zheng, Y Lou, B Han
    J Cancer, 2018-01-01;9(2):367-374.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  204. Conserved structures formed by heterogeneous RNA sequences drive silencing of an inflammation responsive post-transcriptional operon
    Authors: A Basu, N Jain, BS Tolbert, AA Komar, B Mazumder
    Nucleic Acids Res., 2017-12-15;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  205. Liraglutide dictates macrophage phenotype in apolipoprotein E null mice during early atherosclerosis
    Authors: R Bruen, S Curley, S Kajani, D Crean, ME O'Reilly, MB Lucitt, CG Godson, FC McGillicud, O Belton
    Cardiovasc Diabetol, 2017-11-06;16(1):143.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  206. Ex Vivo Profiling of PD-1 Blockade Using Organotypic Tumor Spheroids
    Authors: RW Jenkins, AR Aref, PH Lizotte, E Ivanova, S Stinson, CW Zhou, M Bowden, J Deng, H Liu, D Miao, MX He, W Walker, G Zhang, T Tian, C Cheng, Z Wei, S Palakurthi, M Bittinger, H Vitzthum, JW Kim, A Merlino, M Quinn, C Venkataram, JA Kaplan, A Portell, PC Gokhale, B Phillips, A Smart, A Rotem, RE Jones, L Keogh, M Anguiano, L Stapleton, Z Jia, M Barzily-Ro, I Cañadas, TC Thai, MR Hammond, R Vlahos, ES Wang, H Zhang, S Li, GJ Hanna, W Huang, MP Hoang, A Piris, JP Eliane, AO Stemmer-Ra, L Cameron, MJ Su, P Shah, B Izar, M Thakuria, NR LeBoeuf, G Rabinowits, V Gunda, S Parangi, JM Cleary, BC Miller, S Kitajima, R Thummalapa, B Miao, TU Barbie, V Sivathanu, J Wong, WG Richards, R Bueno, CH Yoon, J Miret, M Herlyn, LA Garraway, EM Van Allen, GJ Freeman, PT Kirschmeie, JH Lorch, PA Ott, FS Hodi, KT Flaherty, RD Kamm, GM Boland, KK Wong, D Dornan, CP Paweletz, DA Barbie
    Cancer Discov, 2017-11-03;0(0):.
    Species: Human, Mouse
    Sample Types: Organoids
    Applications: Bioassay
  207. IFN-? and TNF-? synergism may provide a link between psoriasis and inflammatory atherogenesis
    Authors: NN Mehta, HL Teague, WR Swindell, Y Baumer, NL Ward, X Xing, B Baugous, A Johnston, AA Joshi, J Silverman, DH Barnes, L Wolterink, RP Nair, PE Stuart, M Playford, JJ Voorhees, MK Sarkar, JT Elder, K Gallagher, SK Ganesh, JE Gudjonsson
    Sci Rep, 2017-10-23;7(1):13831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  208. Priming and Activation of Inflammasome by Canarypox Virus Vector ALVAC via the cGAS/IFI16-STING-Type I IFN Pathway and AIM2 Sensor
    Authors: F Liu, Q Niu, X Fan, C Liu, J Zhang, Z Wei, W Hou, TD Kanneganti, ML Robb, JH Kim, NL Michael, J Sun, L Soong, H Hu
    J. Immunol., 2017-09-25;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  209. SPI-2/CrmA inhibits IFN-? induction by targeting TBK1/IKK?
    Authors: Y Qin, M Li, SL Zhou, W Yin, Z Bian, HB Shu
    Sci Rep, 2017-09-05;7(1):10495.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency
    Authors: N Starc, D Ingo, A Conforti, V Rossella, L Tomao, A Pitisci, F De Mattia, I Brigida, M Algeri, M Montanari, G Palumbo, P Merli, P Rossi, A Aiuti, F Locatelli, ME Bernardo
    Sci Rep, 2017-08-15;7(1):8153.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  211. Rheumatoid arthritis and psoriatic arthritis synovial fluid stimulates prolactin production by macrophages
    Authors: MW Tang, S Garcia, B Malvar Fer, DM Gerlag, PP Tak, KA Reedquist
    J. Leukoc. Biol., 2017-06-22;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Mitochondrial DNA depletion induces innate immune dysfunction rescued by interferon-?
    Authors: JD Widdringto, A Gomez-Dura, JS Steyn, A Pyle, MH Ruchaud-Sp, J Scott, SV Baudouin, AJ Rostron, J Simpson, PF Chinnery F
    J. Allergy Clin. Immunol., 2017-06-17;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  213. A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors
    Authors: A Pavesi, AT Tan, S Koh, A Chia, M Colombo, E Antonecchi, C Miccolis, E Ceccarello, G Adriani, MT Raimondi, RD Kamm, A Bertoletti
    JCI Insight, 2017-06-15;2(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Image based Machine Learning for identification of macrophage subsets
    Authors: HM Rostam, PM Reynolds, MR Alexander, N Gadegaard, AM Ghaemmagha
    Sci Rep, 2017-06-14;7(1):3521.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  215. NOX2-dependent ATM kinase activation dictates pro-inflammatory macrophage phenotype and improves effectiveness to radiation therapy
    Authors: Q Wu, A Allouch, A Paoletti, C Leteur, C Mirjolet, I Martins, L Voisin, F Law, H Dakhli, E Mintet, M Thoreau, Z Muradova, M Gauthier, O Caron, F Milliat, DM Ojcius, F Rosselli, E Solary, N Modjtahedi, E Deutsch, JL Perfettini
    Cell Death Differ., 2017-06-02;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  216. Colony-stimulating factor 1 receptor blockade inhibits tumor growth by altering the polarization of tumor-associated macrophages in hepatocellular carcinoma
    Authors: JY Ao, XD Zhu, ZT Chai, H Cai, YY Zhang, KZ Zhang, LQ Kong, N Zhang, BG Ye, DN Ma, HC Sun
    Mol. Cancer Ther., 2017-06-01;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Human Neutrophils Produce CCL23 in Response to Various TLR-Agonists and TNF?
    Authors: F Arruda-Sil, F Bianchetto, S Gasperini, S Polletti, E Cosentino, N Tamassia, MA Cassatella
    Front Cell Infect Microbiol, 2017-05-12;7(0):176.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  218. Monocytic microRNA profile associated with coronary collateral artery function in chronic total occlusion patients
    Authors: N Hakimzadeh, J Elias, GWM Wijntjens, R Theunissen, A van Weert, MW Smulders, N van den Ak, PD Moerland, HJ Verberne, LP Hoebers, JPS Henriques, AM van der La, M Ilhan, M Post, SCAM Bekkers, JJ Piek
    Sci Rep, 2017-05-08;7(1):1532.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Psoriatic cutaneous inflammation promotes human monocyte differentiation into active osteoclasts, facilitating bone damage
    Authors: A Raimondo, S Lembo, RD Caprio, G Donnarumma, G Monfrecola, N Balato, F Ayala, A Balato
    Eur. J. Immunol., 2017-05-02;0(0):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  220. Differential regulation of surface receptor expression, proliferation, and apoptosis in HaCaT cells stimulated with interferon-?, interleukin-4, tumor necrosis factor-?, or muramyl dipeptide
    Authors: E El Darzi, S Bazzi, S Daoud, KS Echtay, GM Bahr
    Int J Immunopathol Pharmacol, 2017-04-28;0(0):3946320177076.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions
    Authors: X Wang, R Wilkinson, K Kildey, J Potriquet, J Mulvenna, RJ Lobb, A Möller, N Cloonan, P Mukhopadhy, AJ Kassianos, H Healy
    J Extracell Vesicles, 2017-04-21;6(1):1314073.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  222. Salt suppresses IFN? inducible chemokines through the IFN?-JAK1-STAT1 signaling pathway in proximal tubular cells
    Authors: Y Arai, D Takahashi, K Asano, M Tanaka, M Oda, SBH Ko, MSH Ko, S Mandai, N Nomura, T Rai, S Uchida, E Sohara
    Sci Rep, 2017-04-20;7(0):46580.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  223. Interferon-? Released by Activated CD8(+) T Lymphocytes Impairs the Calcium Resorption Potential of Osteoclasts in Calcified Human Aortic Valves
    Authors: E Nagy, Y Lei, E Martínez-M, SC Body, F Schlotter, M Creager, A Assmann, K Khabbaz, P Libby, GK Hansson, E Aikawa
    Am. J. Pathol., 2017-04-19;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  224. Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
    Authors: E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux
    Stem Cell Res Ther, 2017-04-17;8(1):79.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  225. Interferon-? induced insufficient autophagy contributes to p62-dependent apoptosis of epithelial cells in chronic rhinosinusitis with nasal polyps
    Authors: BF Wang, PP Cao, ZC Wang, ZY Li, ZZ Wang, J Ma, B Liao, YK Deng, XB Long, K Xu, H Wang, H Wang, M Zeng, X Lu, Z Liu
    Allergy, 2017-04-04;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  226. Mutual regulation of tumour vessel normalization and immunostimulatory reprogramming
    Authors: L Tian, A Goldstein, H Wang, H Ching Lo, I Sun Kim, T Welte, K Sheng, LE Dobrolecki, X Zhang, N Putluri, TL Phung, SA Mani, F Stossi, A Sreekumar, MA Mancini, WK Decker, C Zong, MT Lewis, XH Zhang
    Nature, 2017-04-03;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  227. Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36?
    Authors: JS Ainscough, T Macleod, D McGonagle, R Brakefield, JM Baron, A Alase, M Wittmann, M Stacey
    Proc. Natl. Acad. Sci. U.S.A, 2017-03-13;114(13):E2748-E2757.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  228. Cell type-dependent regulation of free ISG15 levels and ISGylation
    Authors: AC Tecalco Cr, K Mejía-Barr
    J Cell Commun Signal, 2017-03-11;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  229. VHL promotes immune response against renal cell carcinoma via NF-?B-dependent regulation of VCAM-1
    Authors: D Labrousse-, E Martínez-A, M Corral-Esc, R Bienes-Mar, J Berridy, L Serrano-Ov, E Conde, ML García-Ber, JM Giménez-Ba, AS Salinas-Sá, R Sánchez-Pr, M Yao, M Lasa, MJ Calzada
    J. Cell Biol, 2017-02-24;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  230. Mesenchymal stromal cells as vehicles of tetravalent bispecific Tandab (CD3/CD19) for the treatment of B cell lymphoma combined with IDO pathway inhibitor D-1-methyl-tryptophan
    Authors: X Zhang, Y Yang, L Zhang, Y Lu, Q Zhang, D Fan, Y Zhang, Y Zhang, Z Ye, D Xiong
    J Hematol Oncol, 2017-02-23;10(1):56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  231. ErbB4 signaling stimulates pro-inflammatory macrophage apoptosis and limits colonic inflammation
    Authors: MA Schumacher, M Hedl, C Abraham, JK Bernard, PR Lozano, JJ Hsieh, D Almohazey, EB Bucar, S Punit, PJ Dempsey, MR Frey
    Cell Death Dis, 2017-02-23;8(2):e2622.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  232. Th1high in tumor microenvironment is an indicator of poor prognosis for patients with NSCLC
    Authors: J Huang, F Shen, H Huang, C Ling, G Zhang
    Oncotarget, 2017-02-21;8(8):13116-13125.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  233. Macrophages confer survival signals via CCR1-dependent translational MCL-1 induction in chronic lymphocytic leukemia
    Authors: MH van Atteku, S Terpstra, E Slinger, M von Linder, PD Moerland, A Jongejan, AP Kater, E Eldering
    Oncogene, 2017-02-13;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Cytosolic DNA Promotes Signal Transducer and Activator of Transcription 3 (STAT3) Phosphorylation by TANK-binding kinase 1 (TBK1) to Restrain STAT3 Activity
    Authors: HC Hsia, JE Hutti, AS Baldwin
    J. Biol. Chem, 2017-02-10;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  235. Involvement of ?-defensin 130 (DEFB130) in the macrophage microbicidal mechanisms for killing Plasmodium falciparum
    Authors: MA Terkawi, R Takano, A Furukawa, F Murakoshi, K Kato
    Sci Rep, 2017-02-09;7(0):41772.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Guanylate-binding protein 1 (GBP1) contributes to the immunity of human mesenchymal stromal cells against Toxoplasma gondii
    Authors: A Qin, DH Lai, Q Liu, W Huang, YP Wu, X Chen, S Yan, H Xia, G Hide, ZR Lun, FJ Ayala, AP Xiang
    Proc. Natl. Acad. Sci. U.S.A, 2017-01-25;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  237. Curcumin induces apoptosis in human leukemic cell lines through an IFIT2-dependent pathway
    Authors: Y Zhang, Y Kong, S Liu, L Zeng, L Wan, Z Zhang
    Cancer Biol. Ther, 2017-01-10;0(0):1-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  238. IFN type I and II induce BAFF secretion from human decidual stromal cells
    Authors: AC Lundell, I Nordstr”m, K Andersson, C Lundqvist, E Telemo, S Nava, H Kaipe, A Rudin
    Sci Rep, 2017-01-06;7(0):39904.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  239. Mycobacterium tuberculosis ESAT6 and CPF10 Induce Adenosine Deaminase 2 mRNA Expression in Monocyte-Derived Macrophages
    Authors: MJ Bae, S Ryu, HJ Kim, SI Cha, CH Kim, J Lee
    Tuberc Respir Dis (Seoul), 2016-12-30;80(1):77-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Thioredoxin-1 Selectively Activates Transglutaminase 2 in the Extracellular Matrix of the Small Intestine: Implications for Celiac Disease
    Authors: Nicholas M Plugis
    J. Biol. Chem, 2016-12-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  241. Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells
    PLoS ONE, 2016-12-01;11(12):e0167361.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  242. Fc engineering approaches to enhance the agonism and effector functions of an anti-OX40 antibody
    Authors: Mark L Chiu
    J. Biol. Chem., 2016-11-17;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  243. Regulation and function of Bone Morphogenetic Protein signaling in colonic injury and inflammation
    Authors: Andrea Todisco
    Am. J. Physiol. Gastrointest. Liver Physiol., 2016-11-17;0(0):ajpgi.00169.2.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  244. Procyanidin A2 Modulates IL-4-Induced CCL26 Production in Human Alveolar Epithelial Cells
    Int J Mol Sci, 2016-11-12;17(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  245. Duck Tembusu Virus Nonstructural Protein 1 Antagonizes IFN-? Signaling Pathways by Targeting VISA
    Authors: Qiyun Zhu
    J. Immunol., 2016-11-07;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  246. Interferon-? Promotes Antibody-mediated Fratricide of Acute Myeloid Leukemia Cells
    Authors: Susheela Tridandapa
    J. Biol. Chem., 2016-10-25;291(49):25656-25666.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  247. MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations
    Authors: Robert Sabat
    Mediators Inflamm., 2016-10-23;2016(0):4097574.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  248. Programmed death-ligand 1 (PD-L1) characterization of circulating tumor cells (CTCs) in muscle invasive and metastatic bladder cancer patients
    BMC Cancer, 2016-09-22;16(1):744.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  249. Interferon-? blocks signalling through PDGFR? in human brain pericytes
    J Neuroinflammation, 2016-09-21;13(1):249.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  250. TLR3 preconditioning enhances the therapeutic efficacy of umbilical cord mesenchymal stem cells in TNBS-induced colitis via the TLR3-Jagged-1-Notch-1 pathway
    Mucosal Immunol, 2016-09-21;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Diverse fates of uracilated HIV-1 DNA during infection of myeloid lineage cells
    Elife, 2016-09-20;5(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  252. Gene-expression profiling of different arms of lymphatic vasculature identifies candidates for manipulation of cell traffic
    Proc Natl Acad Sci USA, 2016-09-06;113(38):10643-10648.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  253. MiR-146a modulates macrophage polarization in systemic juvenile idiopathic arthritis by targeting INHBA
    Mol Immunol, 2016-08-16;77(0):205-212.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  254. Identification of a major epitope by anti-interferon-? autoantibodies in patients with mycobacterial disease
    Nat Med, 2016-08-15;0(0):.
    Species: Human
    Sample Types: Plasma
    Applications: Western Blot
  255. PD-1/PD-L1 blockade enhances T cell activity and antitumor efficacy of imatinib in gastrointestinal stromal tumors
    Clin Cancer Res, 2016-07-28;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  256. Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype
    Sci Rep, 2016-07-19;6(0):29712.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  257. CD1c-Expression by Monocytes - Implications for the Use of Commercial CD1c+ Dendritic Cell Isolation Kits
    Authors: Martine Schrøder
    PLoS ONE, 2016-06-16;11(6):e0157387.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  258. Monocyte Differentiation towards Protumor Activity Does Not Correlate with M1 or M2 Phenotypes
    Authors: G Karina Chimal-Ram
    J Immunol Res, 2016-06-08;2016(0):6031486.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  259. Soluble Siglec-9 suppresses arthritis in a collagen-induced arthritis mouse model and inhibits M1 activation of RAW264.7 macrophages
    Authors: Takuya Matsumoto
    Arthritis Res Ther, 2016-06-07;18(1):133.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  260. Effective Cytotoxic T Lymphocyte Targeting of Persistent HIV-1 during Antiretroviral Therapy Requires Priming of Naive CD8+ T Cells
    Authors: Kellie N Smith
    MBio, 2016-05-31;7(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  261. Immunomodulation by mesenchymal stem cells in treating human autoimmune disease-associated lung fibrosis
    Authors: M Liu, X Zeng, J Wang, Z Fu, J Wang, M Liu, D Ren, B Yu, L Zheng, X Hu, W Shi, J Xu
    Stem Cell Res Ther, 2016-04-23;7(1):63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  262. B cell IFN-? receptor signaling promotes autoimmune germinal centers via cell-intrinsic induction of BCL-6
    Authors: SW Jackson, HM Jacobs, T Arkatkar, EM Dam, NE Scharping, NS Kolhatkar, B Hou, JH Buckner, DJ Rawlings
    J Exp Med, 2016-04-11;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex.
    Authors: Guo Z, Zheng L, Liao X, Geller D
    PLoS ONE, 2016-01-11;11(1):e0146640.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  264. IDO Downregulation Induces Sensitivity to Pemetrexed, Gemcitabine, FK866, and Methoxyamine in Human Cancer Cells.
    Authors: Maleki Vareki S, Chen D, Di Cresce C, Ferguson P, Figueredo R, Pampillo M, Rytelewski M, Vincent M, Min W, Zheng X, Koropatnick J
    PLoS ONE, 2015-11-18;10(11):e0143435.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  265. PRC2 Epigenetically Silences Th1-Type Chemokines to Suppress Effector T-Cell Trafficking in Colon Cancer.
    Authors: Nagarsheth N, Peng D, Kryczek I, Wu K, Li W, Zhao E, Zhao L, Wei S, Frankel T, Vatan L, Szeliga W, Dou Y, Owens S, Marquez V, Tao K, Huang E, Wang G, Zou W
    Cancer Res, 2015-11-13;76(2):275-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  266. Interferon-gamma Inhibits Ebola Virus Infection.
    Authors: Rhein B, Powers L, Rogers K, Anantpadma M, Singh B, Sakurai Y, Bair T, Miller-Hunt C, Sinn P, Davey R, Monick M, Maury W
    PLoS Pathog, 2015-11-12;11(11):e1005263.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  267. Sphingosine 1 Phosphate at the Blood Brain Barrier: Can the Modulation of S1P Receptor 1 Influence the Response of Endothelial Cells and Astrocytes to Inflammatory Stimuli?
    Authors: Spampinato S, Obermeier B, Cotleur A, Love A, Takeshita Y, Sano Y, Kanda T, Ransohoff R
    PLoS ONE, 2015-07-21;10(7):e0133392.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  268. Activated Brain Endothelial Cells Cross-Present Malaria Antigen.
    Authors: Howland S, Poh C, Renia L
    PLoS Pathog, 2015-06-05;11(6):e1004963.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  269. Mouse pancreatic beta cells express MHC class II and stimulate CD4(+) T cells to proliferate.
    Authors: Zhao Y, Scott N, Quah H, Krishnamurthy B, Bond F, Loudovaris T, Mannering S, Kay T, Thomas H
    Eur J Immunol, 2015-05-28;45(9):2494-503.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage.
    Authors: Catanzaro D, Rancan S, Orso G, Dall'Acqua S, Brun P, Giron M, Carrara M, Castagliuolo I, Ragazzi E, Caparrotta L, Montopoli M
    PLoS ONE, 2015-05-08;10(5):e0125375.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  271. An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells.
    Authors: Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, Ghigo D, Riganti C
    PLoS ONE, 2015-05-08;10(5):e0126159.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  272. Identification of a nuclear export sequence in the MHC CIITA.
    Authors: Chiu E, Gold T, Fettig V, LeVasseur M, Cressman D
    J Immunol, 2015-05-06;194(12):6102-11.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  273. TIM-3/Gal-9 interaction induces IFNgamma-dependent IDO1 expression in acute myeloid leukemia blast cells.
    Authors: Folgiero V, Cifaldi L, Li Pira G, Goffredo B, Vinti L, Locatelli F
    J Hematol Oncol, 2015-04-16;8(0):36.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  274. Impaired T cell responsiveness to interleukin-6 in hematological patients with invasive aspergillosis.
    Authors: Camargo J, Bhimji A, Kumar D, Kaul R, Pavan R, Schuh A, Seftel M, Lipton J, Gupta V, Humar A, Husain S
    PLoS ONE, 2015-04-02;10(4):e0123171.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  275. IFN-gamma from lymphocytes induces PD-L1 expression and promotes progression of ovarian cancer.
    Authors: Abiko K, Matsumura N, Hamanishi J, Horikawa N, Murakami R, Yamaguchi K, Yoshioka Y, Baba T, Konishi I, Mandai M
    Br J Cancer, 2015-03-31;112(9):1501-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  276. Characterization of pancreatic NMDA receptors as possible drug targets for diabetes treatment.
    Authors: Marquard J, Otter S, Welters A, Stirban A, Fischer A, Eglinger J, Herebian D, Kletke O, Klemen M, Stozer A, Wnendt S, Piemonti L, Kohler M, Ferrer J, Thorens B, Schliess F, Rupnik M, Heise T, Berggren P, Klocker N, Meissner T, Mayatepek E, Eberhard D, Kragl M, Lammert E
    Nat Med, 2015-03-16;21(4):363-72.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  277. Epidermal Expression and Regulation of Interleukin-33 during Homeostasis and Inflammation: Strong Species Differences.
    Authors: Sundnes O, Pietka W, Loos T, Sponheim J, Rankin A, Pflanz S, Bertelsen V, Sitek J, Hol J, Haraldsen G, Khnykin D
    J Invest Dermatol, 2015-03-04;135(7):1771-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  278. Granulocyte-macrophage colony stimulatory factor enhances the pro-inflammatory response of interferon-gamma-treated macrophages to Pseudomonas aeruginosa infection.
    Authors: Singh S, Barr H, Liu Y, Robins A, Heeb S, Williams P, Fogarty A, Camara M, Martinez-Pomares L
    PLoS ONE, 2015-02-23;10(2):e0117447.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  279. Regulation of IL-17A responses in human airway smooth muscle cells by Oncostatin M.
    Authors: Kwofie K, Scott M, Rodrigues R, Guerette J, Radford K, Nair P, Richards C
    Respir Res, 2015-02-07;16(0):14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  280. ChemR23, the receptor for chemerin and resolvin E1, is expressed and functional on M1 but not on M2 macrophages.
    Authors: Herova M, Schmid M, Gemperle C, Hersberger M
    J Immunol, 2015-01-30;194(5):2330-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  281. Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells.
    Authors: Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M
    Invest Ophthalmol Vis Sci, 2015-01-20;56(2):1051-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  282. The activation status of human macrophages presenting antigen determines the efficiency of Th17 responses.
    Authors: Arnold C, Gordon P, Barker R, Wilson H
    Immunobiology, 2015-01-01;220(1):10-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  283. Motor, visual and emotional deficits in mice after closed-head mild traumatic brain injury are alleviated by the novel CB2 inverse agonist SMM-189.
    Authors: Reiner A, Heldt S, Presley C, Guley N, Elberger A, Deng Y, D'Surney L, Rogers J, Ferrell J, Bu W, Del Mar N, Honig M, Gurley S, Moore B
    Int J Mol Sci, 2014-12-31;16(1):758-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Disease-associated polymorphisms in ERAP1 do not alter endoplasmic reticulum stress in patients with ankylosing spondylitis.
    Authors: Kenna T, Lau M, Keith P, Ciccia F, Costello M, Bradbury L, Low P, Agrawal N, Triolo G, Alessandro R, Robinson P, Thomas G, Brown M
    Genes Immun, 2014-11-06;16(1):35-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  285. Monitoring the initiation and kinetics of human dendritic cell-induced polarization of autologous naive CD4+ T cells.
    Authors: Oth, Tammy, Schnijderberg, Melanie, Senden-Gijsbers, Birgit L, Germeraad, Wilfred, Bos, Gerard M, Vanderlocht, Joris
    PLoS ONE, 2014-08-21;9(8):e103725.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  286. Nitric oxide enhances Th9 cell differentiation and airway inflammation.
    Authors: Niedbala W, Besnard A, Nascimento D, Donate P, Sonego F, Yip E, Guabiraba R, Chang H, Fukada S, Salmond R, Schmitt E, Bopp T, Ryffel B, Liew F
    Nat Commun, 2014-08-07;5(0):4575.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  287. IFN-gamma primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b.
    Authors: Wu C, Xue Y, Wang P, Lin L, Liu Q, Li N, Xu J, Cao X
    J Immunol, 2014-08-04;193(6):3036-44.
  288. Maresin biosynthesis and identification of maresin 2, a new anti-inflammatory and pro-resolving mediator from human macrophages.
    Authors: Deng B, Wang C, Arnardottir H, Li Y, Cheng C, Dalli J, Serhan C
    PLoS ONE, 2014-07-18;9(7):e102362.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  289. Annexin V incorporated into influenza virus particles inhibits gamma interferon signaling and promotes viral replication.
    Authors: Berri F, Haffar G, Le V, Sadewasser A, Paki K, Lina B, Wolff T, Riteau B
    J Virol, 2014-07-16;88(19):11215-28.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  290. The NKG2D ligand ULBP2 is specifically regulated through an invariant chain-dependent endosomal pathway.
    Authors: Uhlenbrock F, Hagemann-Jensen M, Kehlet S, Andresen L, Pastorekova S, Skov S
    J Immunol, 2014-07-14;193(4):1654-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  291. A role for human brain pericytes in neuroinflammation.
    Authors: Jansson D, Rustenhoven J, Feng S, Hurley D, Oldfield R, Bergin P, Mee E, Faull R, Dragunow M
    J Neuroinflammation, 2014-06-11;11(0):104.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  292. Hemin controls T cell polarization in sickle cell alloimmunization.
    Authors: Zhong H, Bao W, Friedman D, Yazdanbakhsh K
    J Immunol, 2014-05-30;193(1):102-10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  293. Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency.
    Authors: Cichocki F, Schlums H, Li H, Stache V, Holmes T, Lenvik T, Chiang S, Miller J, Meeths M, Anderson S, Bryceson Y
    J Exp Med, 2014-05-19;211(6):1079-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  294. Skin-resident T cells sense ultraviolet radiation-induced injury and contribute to DNA repair.
    Authors: MacLeod A, Rudolph R, Corriden R, Ye I, Garijo O, Havran W
    J Immunol, 2014-05-07;192(12):5695-702.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  295. The SLE transcriptome exhibits evidence of chronic endotoxin exposure and has widespread dysregulation of non-coding and coding RNAs.
    Authors: Shi L, Zhang Z, Yu A, Wang W, Wei Z, Akhter E, Maurer K, Costa Reis P, Song L, Petri M, Sullivan K
    PLoS ONE, 2014-05-05;9(5):e93846.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  296. E2F1 renders prostate cancer cell resistant to ICAM-1 mediated antitumor immunity by NF-kappaB modulation.
    Authors: Ren Z, Kang W, Wang L, Sun B, Ma J, Zheng C, Sun J, Tian Z, Yang X, Xiao W
    Mol Cancer, 2014-04-17;13(0):84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  297. Human adipose-derived stromal/stem cells induce functional CD4+CD25+FoxP3+CD127- regulatory T cells under low oxygen culture conditions.
    Authors: Frazier T, McLachlan J, Gimble J, Tucker H, Rowan B
    Stem Cells Dev, 2014-03-11;23(9):968-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  298. Eosinophils regulate peripheral B cell numbers in both mice and humans.
    Authors: Wong, Tina W, Doyle, Alfred D, Lee, James J, Jelinek, Diane F
    J Immunol, 2014-03-10;192(8):3548-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  299. Innate immune activity conditions the effect of regulatory variants upon monocyte gene expression.
    Authors: Fairfax B, Humburg P, Makino S, Naranbhai V, Wong D, Lau E, Jostins L, Plant K, Andrews R, McGee C, Knight J
    Science, 2014-03-07;343(6175):1246949.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  300. MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation.
    Authors: Lopez-Ramirez M, Wu D, Pryce G, Simpson J, Reijerkerk A, King-Robson J, Kay O, de Vries H, Hirst M, Sharrack B, Baker D, Male D, Michael G, Romero I
    FASEB J, 2014-03-06;28(6):2551-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  301. IL-17 induces an expanded range of downstream genes in reconstituted human epidermis model.
    Authors: Chiricozzi, Andrea, Nograles, Kristine, Johnson-Huang, Leanne M, Fuentes-Duculan, Judilyn, Cardinale, Irma, Bonifacio, Kathleen, Gulati, Nicholas, Mitsui, Hiroshi, Guttman-Yassky, Emma, Suarez-Farinas, Mayte, Krueger, James G
    PLoS ONE, 2014-02-28;9(2):e90284.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  302. A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure.
    Authors: Llop-Guevara A, Chu D, Walker T, Goncharova S, Fattouh R, Silver J, Moore C, Xie J, O'Byrne P, Coyle A, Kolbeck R, Humbles A, Stampfli M, Jordana M
    PLoS ONE, 2014-02-14;9(2):e88714.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  303. Rapid healing of cutaneous leishmaniasis by high-frequency electrocauterization and hydrogel wound care with or without DAC N-055: a randomized controlled phase IIa trial in Kabul.
    Authors: Jebran A, Schleicher U, Steiner R, Wentker P, Mahfuz F, Stahl H, Amin F, Bogdan C, Stahl K
    PLoS Negl Trop Dis, 2014-02-13;8(2):e2694.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  304. An airway epithelial iNOS-DUOX2-thyroid peroxidase metabolome drives Th1/Th2 nitrative stress in human severe asthma.
    Authors: Voraphani N, Gladwin M, Contreras A, Kaminski N, Tedrow J, Milosevic J, Bleecker E, Meyers D, Ray A, Ray P, Erzurum S, Busse W, Zhao J, Trudeau J, Wenzel S
    Mucosal Immunol, 2014-02-12;7(5):1175-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  305. cmvIL-10 stimulates the invasive potential of MDA-MB-231 breast cancer cells.
    Authors: Valle Oseguera, Cendy A, Spencer, Juliet V
    PLoS ONE, 2014-02-10;9(2):e88708.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  306. No major role for insulin-degrading enzyme in antigen presentation by MHC molecules.
    Authors: Culina S, Mauvais F, Hsu H, Burgevin A, Guenette S, Moser A, van Endert P
    PLoS ONE, 2014-02-07;9(2):e88365.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  307. Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators.
    Authors: Milwid, Jack M, Elman, Jessica, Li, Matthew, Shen, Keyue, Manrai, Arjun, Gabow, Aaron, Yarmush, Joshua, Jiao, Yunxin, Fletcher, Anne, Lee, Jungwoo, Cima, Michael, Yarmush, Martin L, Parekkadan, Biju
    Mol Ther, 2014-02-05;22(5):999-1007.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  308. CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis.
    Authors: Parlato M, Souza-Fonseca-Guimaraes F, Philippart F, Misset B, Adib-Conquy M, Cavaillon J
    J Immunol, 2014-02-05;192(5):2449-59.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  309. Transcriptomic profiling of the development of the inflammatory response in human monocytes in vitro.
    Authors: Italiani, Paola, Mazza, Emilia M, Lucchesi, Davide, Cifola, Ingrid, Gemelli, Claudia, Grande, Alexis, Battaglia, Cristina, Bicciato, Silvio, Boraschi, Diana
    PLoS ONE, 2014-02-03;9(2):e87680.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  310. Increased metabolite levels of glycolysis and pentose phosphate pathway in rabbit atherosclerotic arteries and hypoxic macrophage.
    Authors: Yamashita A, Zhao Y, Matsuura Y, Yamasaki K, Moriguchi-Goto S, Sugita C, Iwakiri T, Okuyama N, Koshimoto C, Kawai K, Tamaki N, Zhao S, Kuge Y, Asada Y
    PLoS ONE, 2014-01-23;9(1):e86426.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  311. The productive entry pathway of HIV-1 in macrophages is dependent on endocytosis through lipid rafts containing CD4.
    Authors: van Wilgenburg, Bonnie, Moore, Michael, James, William, Cowley, Sally A
    PLoS ONE, 2014-01-22;9(1):e86071.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  312. TRIM38 inhibits TNFalpha- and IL-1beta-triggered NF-kappaB activation by mediating lysosome-dependent degradation of TAB2/3.
    Authors: Hu M, Yang Q, Zhang J, Liu S, Zhang Y, Lin H, Huang Z, Wang Y, Zhang X, Zhong B, Shu H
    Proc Natl Acad Sci U S A, 2014-01-13;111(4):1509-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.
    Authors: Suzuki, Hitoshi, Raska, Milan, Yamada, Koshi, Moldoveanu, Zina, Julian, Bruce A, Wyatt, Robert J, Tomino, Yasuhiko, Gharavi, Ali G, Novak, Jan
    J Biol Chem, 2014-01-07;289(8):5330-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  314. G protein-coupled bile acid receptor 1 stimulation mediates arterial vasodilation through a K(Ca)1.1 (BK(Ca))-dependent mechanism.
    Authors: Fryer, Ryan M, Ng, Khing Jo, Nodop Mazurek, Suzanne, Patnaude, Lori, Skow, Donna J, Muthukumarana, Akalushi, Gilpin, Kyle E, Dinallo, Roger M, Kuzmich, Daniel, Lord, John, Sanyal, Sulagna, Yu, Hui, Harcken, Christia, Cerny, Matthew, Hickey, Eugene R, Modis, Louise K
    J Pharmacol Exp Ther, 2014-01-07;348(3):421-31.
    Species: Human
    Sample Types: Plasma
    Applications: Bioassay
  315. Tie2 signaling cooperates with TNF to promote the pro-inflammatory activation of human macrophages independently of macrophage functional phenotype.
    Authors: Garcia S, Krausz S, Ambarus C, Fernandez B, Hartkamp L, van Es I, Hamann J, Baeten D, Tak P, Reedquist K
    PLoS ONE, 2014-01-03;9(1):e82088.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  316. slanDCs selectively accumulate in carcinoma-draining lymph nodes and marginate metastatic cells.
    Authors: Vermi W, Micheletti A, Lonardi S, Costantini C, Calzetti F, Nascimbeni R, Bugatti M, Codazzi M, Pinter P, Schakel K, Tamassia N, Cassatella M
    Nat Commun, 2014-01-01;5(0):3029.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  317. Identification of novel human leukocyte antigen-A*0201-restricted, cytotoxic T lymphocyte epitopes on CD133 for cancer stem cell immunotherapy.
    Authors: Ji, Jianfei, Judkowski, Valeria, Liu, Gentao, Wang, Hongqian, Bunying, Alcinett, Li, Zhenhua, Xu, Minlin, Bender, James, Pinilla, Clemenci, Yu, John S
    Stem Cells Transl Med, 2013-12-27;3(3):356-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  318. The impact of viral evolution and frequency of variant epitopes on primary and memory human immunodeficiency virus type 1-specific CD8(+) T cell responses.
    Authors: Melhem N, Smith K, Huang X, Colleton B, Jiang W, Mailliard R, Mullins J, Rinaldo C
    Virology, 2013-12-20;450(0):34-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  319. Therapeutic efficacy of suppressing the Jak/STAT pathway in multiple models of experimental autoimmune encephalomyelitis.
    Authors: Liu Y, Holdbrooks A, De Sarno P, Rowse A, Yanagisawa L, McFarland B, Harrington L, Raman C, Sabbaj S, Benveniste E, Qin H
    J Immunol, 2013-12-09;192(1):59-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Conditioned media from macrophages of M1, but not M2 phenotype, inhibit the proliferation of the colon cancer cell lines HT-29 and CACO-2.
    Authors: Engstrom A, Erlandsson A, Delbro D, Wijkander J
    Int J Oncol, 2013-12-02;44(2):385-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  321. CD14 mediates Toll-like receptor 4 (TLR4) endocytosis and spleen tyrosine kinase (Syk) and interferon regulatory transcription factor 3 (IRF3) activation in epithelial cells and impairs neutrophil infiltration and Pseudomonas aeruginosa killing in vivo.
    Authors: Roy S, Karmakar M, Pearlman E
    J Biol Chem, 2013-11-25;289(2):1174-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  322. Cyclooxygenase-2 (COX-2) inhibition constrains indoleamine 2,3-dioxygenase 1 (IDO1) activity in acute myeloid leukaemia cells.
    Authors: Iachininoto M, Nuzzolo E, Bonanno G, Mariotti A, Procoli A, Locatelli F, De Cristofaro R, Rutella S
    Molecules, 2013-08-22;18(9):10132-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  323. Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation.
    Authors: Gieseke F, Kruchen A, Tzaribachev N, Bentzien F, Dominici M, Muller I
    Eur J Immunol, 2013-07-23;43(10):2741-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  324. Therapeutical potential of a peptide mimicking the SOCS1 kinase inhibitory region in skin immune responses.
    Authors: Madonna S, Scarponi C, Doti N, Carbone T, Cavani A, Scognamiglio P, Marasco D, Albanesi C
    Eur J Immunol, 2013-05-28;43(7):1883-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  325. Interleukin-22 binding protein (IL-22BP) is constitutively expressed by a subset of conventional dendritic cells and is strongly induced by retinoic acid.
    Authors: Martin J, Beriou G, Heslan M, Chauvin C, Utriainen L, Aumeunier A, Scott C, Mowat A, Cerovic V, Houston S, Leboeuf M, Hubert F, Hemont C, Merad M, Milling S, Josien R
    Mucosal Immunol, 2013-05-08;7(1):101-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  326. TGR5 signalling inhibits the production of pro-inflammatory cytokines by in vitro differentiated inflammatory and intestinal macrophages in Crohn's disease.
    Authors: Yoneno K, Hisamatsu T, Shimamura K, Kamada N, Ichikawa R, Kitazume M, Mori M, Uo M, Namikawa Y, Matsuoka K, Sato T, Koganei K, Sugita A, Kanai T, Hibi T
    Immunology, 2013-05-01;139(1):19-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  327. IL-17 stimulates differentiation of human anti-inflammatory macrophages and phagocytosis of apoptotic neutrophils in response to IL-10 and glucocorticoids.
    Authors: Zizzo G, Cohen P
    J Immunol, 2013-04-17;190(10):5237-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  328. Anti-CD70 immunocytokines for exploitation of interferon-gamma-induced RIP1-dependent necrosis in renal cell carcinoma.
    Authors: Chen P, Nogusa S, Thapa R, Shaller C, Simmons H, Peri S, Adams G, Balachandran S
    PLoS ONE, 2013-04-17;8(4):e61446.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  329. The internal architecture of leukocyte lipid body organelles captured by three-dimensional electron microscopy tomography.
    Authors: Melo, Rossana, Paganoti, Guillher, Dvorak, Ann M, Weller, Peter F
    PLoS ONE, 2013-03-26;8(3):e59578.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  330. Anti-GM-CSF autoantibodies in patients with cryptococcal meningitis.
    Authors: Rosen L, Freeman A, Yang L, Jutivorakool K, Olivier K, Angkasekwinai N, Suputtamongkol Y, Bennett J, Pyrgos V, Williamson P, Ding L, Holland S, Browne S
    J Immunol, 2013-03-18;190(8):3959-66.
    Species: Human
    Sample Types: Plasma
    Applications: Bioassay
  331. Inhibition of hepatitis B virus gene expression and replication by ribonuclease P.
    Authors: Xia, Chuan, Chen, Yuan-Chu, Gong, Hao, Zeng, Wenbo, Vu, Gia-Phon, Trang, Phong, Lu, Sangwei, Wu, Jianguo, Liu, Fenyong
    Mol Ther, 2013-03-12;21(5):995-1003.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  332. Loss of methylation at the IFNG promoter and CNS-1 is associated with the development of functional IFN-gamma memory in human CD4(+) T lymphocytes.
    Authors: Dong J, Chang H, Ivascu C, Qian Y, Rezai S, Okhrimenko A, Cosmi L, Maggi L, Eckhardt F, Wu P, Sieper J, Alexander T, Annunziato F, Gossen M, Li J, Radbruch A, Thiel A
    Eur J Immunol, 2013-03-01;43(3):793-804.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  333. STAT2 deficiency and susceptibility to viral illness in humans.
    Authors: Hambleton, Sophie, Goodbourn, Stephen, Young, Dan F, Dickinson, Paul, Mohamad, Siti M B, Valappil, Manoj, McGovern, Naomi, Cant, Andrew J, Hackett, Scott J, Ghazal, Peter, Morgan, Neil V, Randall, Richard
    Proc Natl Acad Sci U S A, 2013-02-07;110(8):3053-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  334. Differential regulation of interleukin-12 (IL-12)/IL-23 by Tim-3 drives T(H)17 cell development during hepatitis C virus infection.
    Authors: Wang, Jia M, Shi, Lei, Ma, Cheng J, Ji, Xiao J, Ying, Ruo S, Wu, Xiao Y, Wang, Ke S, Li, Guangyu, Moorman, Jonathan, Yao, Zhi Q
    J Virol, 2013-02-06;87(8):4372-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  335. Susceptibility-associated genetic variation at IL12B enhances Th1 polarization in psoriasis.
    Authors: Johnston A, Xing X, Swindell W, Kochkodan J, Riblett M, Nair R, Stuart P, Ding J, Voorhees J, Elder J, Gudjonsson J
    Hum Mol Genet, 2013-01-31;22(9):1807-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  336. CDK8 kinase phosphorylates transcription factor STAT1 to selectively regulate the interferon response.
    Authors: Bancerek J, Poss Z, Steinparzer I, Sedlyarov V, Pfaffenwimmer T, Mikulic I, Dolken L, Strobl B, Muller M, Taatjes D, Kovarik P
    Immunity, 2013-01-24;38(2):250-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  337. p38alpha senses environmental stress to control innate immune responses via mechanistic target of rapamycin.
    Authors: Katholnig K, Kaltenecker C, Hayakawa H, Rosner M, Lassnig C, Zlabinger G, Gaestel M, Muller M, Hengstschlager M, Horl W, Park J, Saemann M, Weichhart T
    J Immunol, 2013-01-11;190(4):1519-27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  338. Indoleamine 2,3-dioxygenase 1 (IDO1) activity correlates with immune system abnormalities in multiple myeloma.
    Authors: Bonanno G, Mariotti A, Procoli A, Folgiero V, Natale D, De Rosa L, Majolino I, Novarese L, Rocci A, Gambella M, Ciciarello M, Scambia G, Palumbo A, Locatelli F, De Cristofaro R, Rutella S
    J Transl Med, 2012-12-11;10(0):247.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  339. IL-22 suppresses IFN-gamma-mediated lung inflammation in asthmatic patients.
    Authors: Pennino D, Bhavsar P, Effner R, Avitabile S, Venn P, Quaranta M, Marzaioli V, Cifuentes L, Durham S, Cavani A, Eyerich K, Chung K, Schmidt-Weber C, Eyerich S
    J Allergy Clin Immunol, 2012-11-19;131(2):562-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  340. Identification of Axl as a downstream effector of TGF-beta1 during Langerhans cell differentiation and epidermal homeostasis.
    J. Exp. Med., 2012-10-15;209(11):2033-47.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  341. Mycobacterium tuberculosis infection and tissue factor expression in macrophages.
    Authors: Kothari H, Rao L, Vankayalapati R, Pendurthi U
    PLoS ONE, 2012-09-24;7(9):e45700.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  342. Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.
    Authors: Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, Kikushige Y, Kishimoto J, Abe Y, Harada N, Miyamoto T, Iwasaki H, Teshima T, Akashi K
    Blood, 2012-09-18;120(19):4058-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  343. Efficient clearance of early apoptotic cells by human macrophages requires M2c polarization and MerTK induction.
    Authors: Zizzo G, Hilliard B, Monestier M, Cohen P
    J Immunol, 2012-08-31;189(7):3508-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  344. CD34-derived dendritic cells transfected ex vivo with HIV-Gag mRNA induce polyfunctional T-cell responses in nonhuman primates.
    Eur. J. Immunol., 2012-07-04;42(8):2019-30.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  345. The SDF-1α/CXCR4 Axis is Required for Proliferation and Maturation of Human Fetal Pancreatic Endocrine Progenitor Cells.
    Authors: Kayali AG, Lopez AD, Hao E, Hinton A, Hayek A, King CC
    PLoS ONE, 2012-06-22;7(6):e38721.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  346. The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase.
    Authors: Graham LM, Gupta V, Schafer G, Reid DM, Kimberg M, Dennehy KM, Hornsell WG, Guler R, Campanero-Rhodes MA, Palma AS, Feizi T, Kim SK, Sobieszczuk P, Willment JA, Brown GD
    J. Biol. Chem., 2012-06-11;287(31):25964-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  347. Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes.
    J. Invest. Dermatol., 2012-06-07;132(11):2593-600.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  348. Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
    Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
    PLoS ONE, 2012-04-18;7(4):e34965.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  349. Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
    Gene Ther, 2011-11-10;19(10):1035-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  350. Expression and regulation of CCL15 by human airway smooth muscle cells.
    Authors: Joubert P, Lajoie-Kadoch S, Wellemans V, Létuvé S, Tulic MK, Halayko AJ, Hamid Q
    Clin. Exp. Allergy, 2011-11-09;42(1):85-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  351. Natural killer cell-produced IFN-gamma and TNF-alpha induce target cell cytolysis through up-regulation of ICAM-1.
    Authors: Wang R, Jaw JJ, Jaw J, Stutzman NC, Stutzman N, Zou Z, Sun PD
    J Leukoc Biol, 2011-11-01;91(2):299-309.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  352. Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis.
    Authors: Carrier Y, Ma HL, Ramon HE, Napierata L, Small C, O'Toole M, Young DA, Fouser LA, Nickerson-Nutter C, Collins M, Dunussi-Joannopoulos K, Medley QG
    J. Invest. Dermatol., 2011-09-01;131(12):2428-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  353. Identification of IDO-positive and IDO-negative human dendritic cells after activation by various proinflammatory stimuli.
    Authors: Von Bubnoff D, Scheler M, Wilms H, Fimmers R, Bieber T
    J. Immunol., 2011-05-04;186(12):6701-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  354. Human cytomegalovirus IE1 protein elicits a type II interferon-like host cell response that depends on activated STAT1 but not interferon-gamma.
    Authors: Knoblach T, Grandel B, Seiler J, Nevels M, Paulus C
    PLoS Pathog., 2011-04-14;7(4):e1002016.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  355. Epigenetic modulation enhances the therapeutic effect of anti-IL-13R alpha2 antibody in human mesothelioma xenografts.
    Clin. Cancer Res., 2011-02-28;17(9):2819-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  356. Native IL-32 is released from intestinal epithelial cells via a non-classical secretory pathway as a membrane-associated protein.
    Authors: Hasegawa H, Thomas HJ, Schooley K, Born TL
    Cytokine, 2011-01-01;53(1):74-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  357. Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo.
    Authors: Shin HS, Xu F, Bagchi A, Herrup E, Wilhelmsen K
    J. Immunol., 2010-12-17;186(2):1119-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  358. Xanthine oxidoreductase promotes the inflammatory state of mononuclear phagocytes through effects on chemokine expression, peroxisome proliferator-activated receptor-gamma sumoylation, and HIF-1alpha.
    Authors: Gibbings S, Elkins ND, Fitzgerald H, Tiao J, Weyman ME, Shibao G, Fini MA, Wright RM
    J. Biol. Chem., 2010-11-08;286(2):961-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  359. IL-16 promotes T. whipplei replication by inhibiting phagosome conversion and modulating macrophage activation.
    Authors: Ghigo E, Barry AO, Pretat L, Al Moussawi K, Desnues B, Capo C, Kornfeld H, Mege JL
    PLoS ONE, 2010-10-21;5(10):e13561.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  360. B7-h3 augments the inflammatory response and is associated with human sepsis.
    Authors: Zhang G, Wang J, Kelly J
    J. Immunol., 2010-08-09;185(6):3677-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  361. Systematic cytokine receptor profiling reveals GM-CSF as a novel TLR-independent activator of human plasmacytoid predendritic cells.
    Authors: Ghirelli C, Zollinger R, Soumelis V
    Blood, 2010-04-09;115(24):5037-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  362. Evidence for altered Wnt signaling in psoriatic skin.
    Authors: Gudjonsson JE, Johnston A, Stoll SW
    J. Invest. Dermatol., 2010-04-08;130(7):1849-59.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  363. IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes.
    Authors: Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A
    J. Immunol., 2010-03-31;184(9):4880-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  364. A crucial role for Kupffer cell-derived galectin-9 in regulation of T cell immunity in hepatitis C infection.
    Authors: Mengshol JA, Golden-Mason L, Arikawa T
    PLoS ONE, 2010-03-04;5(3):e9504.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  365. Creation of a LIGHT mutant with the capacity to evade the decoy receptor for cancer therapy.
    Authors: Morishige T, Yoshioka Y, Inakura H, Tanabe A, Yao X, Tsunoda S, Tsutsumi Y, Mukai Y, Okada N, Nakagawa S
    Biomaterials, 2010-02-01;31(12):3357-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  366. Expression of interleukin 1-like cytokine interleukin 33 and its receptor complex (ST2L and IL1RAcP) in human pancreatic myofibroblasts.
    Authors: Nishida A, Andoh A, Imaeda H, Inatomi O, Shiomi H, Fujiyama Y
    Gut, 2009-12-08;59(4):531-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  367. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis.
    Authors: Wolk K, Witte E, Warszawska K, Schulze-Tanzil G, Witte K, Philipp S, Kunz S, Docke WD, Asadullah K, Volk HD, Sterry W, Sabat R
    Eur. J. Immunol., 2009-12-01;39(12):3570-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  368. A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
    Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
    Mucosal Immunol, 2009-10-07;3(1):40-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  369. Despite IFN-lambda receptor expression, blood immune cells, but not keratinocytes or melanocytes, have an impaired response to type III interferons: implications for therapeutic applications of these cytokines.
    Authors: Witte K, Gruetz G, Volk HD, Looman AC, Asadullah K, Sterry W, Sabat R, Wolk K
    Genes Immun., 2009-10-01;10(8):702-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  370. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
    Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
    J Biol Chem, 2009-07-15;284(36):24035-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  371. Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.
    Authors: Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT
    Clin. Immunol., 2009-06-25;133(1):27-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  372. Interleukin-32 expression in the pancreas.
    Authors: Nishida A, Andoh A, Inatomi O, Fujiyama Y
    J. Biol. Chem., 2009-04-21;284(26):17868-76.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  373. Interferon-gamma down-regulates NKG2D ligand expression and impairs the NKG2D-mediated cytolysis of MHC class I-deficient melanoma by natural killer cells.
    Authors: Schwinn N, Vokhminova D, Sucker A, Textor S, Striegel S, Moll I, Nausch N, Tuettenberg J, Steinle A, Cerwenka A, Schadendorf D, Paschen A
    Int. J. Cancer, 2009-04-01;124(7):1594-604.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  374. Interleukin-17 and interferon-gamma are produced concomitantly by human coronary artery-infiltrating T cells and act synergistically on vascular smooth muscle cells.
    Authors: Eid RE, Rao DA, Zhou J, Lo SF, Ranjbaran H, Gallo A, Sokol SI, Pfau S, Pober JS, Tellides G
    Circulation, 2009-03-02;119(10):1424-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  375. Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
    Authors: Hao Q, Wang L, Tang H
    Am. J. Physiol., Cell Physiol., 2009-01-28;296(4):C821-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  376. Erythropoietin inhibits respiratory epithelial cell apoptosis in a model of acute lung injury.
    Authors: MacRedmond R, Singhera GK, Dorscheid DR
    Eur. Respir. J., 2009-01-22;33(6):1403-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  377. Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines.
    Authors: Ma P, Bian F, Wang Z, Zheng X, Chotikavanich S, Pflugfelder SC, Li DQ
    Invest. Ophthalmol. Vis. Sci., 2009-01-17;50(6):2702-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  378. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment.
    Authors: Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, Fortugno P, Gonzalvo-Feo S, Franssen JD, Parmentier M, De Pita O, Girolomoni G, Sozzani S
    J. Exp. Med., 2008-12-29;206(1):249-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  379. Immunologic analysis of HIV-uninfected Taiwanese children with BCG-induced disease.
    Authors: Lee WI, Liang FC, Huang JL, Jaing TH, Wang CH, Lin TY, Huang YC, Huang WL, Jou R, Hsieh MY, Chia JH, Wu TL
    J. Clin. Immunol., 2008-12-13;29(3):319-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  380. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.
    Authors: Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H
    J. Allergy Clin. Immunol., 2008-12-03;123(1):179-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  381. Nitric oxide attenuates vascular endothelial cadherin-mediated vascular integrity in human chronic inflammation.
    Authors: Hama S, Takeichi O, Fujisaki K, Tanabe N, Maeno M, Ochiai K
    Clin. Exp. Immunol., 2008-12-01;154(3):384-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  382. Human bronchial intraepithelial T cells produce interferon-gamma and stimulate epithelial cells.
    Authors: Hirosako S, Goto E, Fujii K, Tsumori K, Hirata N, Tsumura S, Kamohara H, Kohrogi H
    Clin. Exp. Immunol., 2008-11-26;155(2):266-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  383. Escherichia coli type 1 pili trigger late IL-8 production by neutrophil-like differentiated PLB-985 cells through a Src family kinase- and MAPK-dependent mechanism.
    Authors: Semiramoth N, Gleizes A, Turbica I, Sandre C, Gorges R, Kansau I, Servin A, Chollet-Martin S
    J. Leukoc. Biol., 2008-11-17;85(2):310-21.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  384. Low expression of the IL-23/Th17 pathway in atopic dermatitis compared to psoriasis.
    Authors: Guttman-Yassky E, Lowes MA, Fuentes-Duculan J, Zaba LC, Cardinale I, Nograles KE, Khatcherian A, Novitskaya I, Carucci JA, Bergman R, Krueger JG
    J. Immunol., 2008-11-15;181(10):7420-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  385. Cytokine-induced CEACAM1 expression on keratinocytes is characteristic for psoriatic skin and contributes to a prolonged lifespan of neutrophils.
    Authors: Rahmoun M, Moles JP, Pedretti N, Mathieu M, Fremaux I, Raison-Peyron N, Lecron JC, Yssel H, Pene J
    J. Invest. Dermatol., 2008-10-09;129(3):671-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  386. Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma.
    Authors: Wente MN, Gaida MM, Mayer C, Michalski CW, Haag N, Giese T, Felix K, Bergmann F, Giese NA, Friess H
    Int. J. Oncol., 2008-08-01;33(2):297-308.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  387. C-reactive protein (CRP) induces chemokine secretion via CD11b/ICAM-1 interaction in human adherent monocytes.
    Authors: Montecucco F, Steffens S, Burger F, Pelli G, Monaco C, Mach F
    J. Leukoc. Biol., 2008-06-30;84(4):1109-19.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  388. Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps.
    Authors: Kato A, Peters A, Suh L, Carter R, Harris KE, Chandra R, Conley D, Grammer LC, Kern R, Schleimer RP
    J. Allergy Clin. Immunol., 2008-04-14;121(6):1385-92, 1392.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  389. Distinct subsets of human invariant NKT cells differentially regulate T helper responses via dendritic cells.
    Authors: Liu TY, Uemura Y, Suzuki M, Narita Y, Hirata S, Ohyama H, Ishihara O, Matsushita S
    Eur. J. Immunol., 2008-04-01;38(4):1012-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  390. Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo.
    Authors: Biancotto A, Iglehart SJ, Lisco A, Vanpouille C, Grivel JC, Lurain NS, Reichelderfer PS, Margolis LB
    AIDS Res. Hum. Retroviruses, 2008-03-01;24(3):453-62.
    Applications: ELISA (Standard)
  391. Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes.
    Authors: Wolk K, Witte K, Witte E, Proesch S, Schulze-Tanzil G, Nasilowska K, Thilo J, Asadullah K, Sterry W, Volk HD, Sabat R
    J. Leukoc. Biol., 2008-02-15;83(5):1181-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  392. Expression and regulation of CCR1 by airway smooth muscle cells in asthma.
    Authors: Joubert P, Lajoie-Kadoch S, Welman M, Dragon S, Letuvee S, Tolloczko B, Halayko AJ, Gounni AS, Maghni K, Hamid Q
    J. Immunol., 2008-01-15;180(2):1268-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  393. The role of interleukin-22 in hepatitis C virus infection.
    Authors: Dambacher J, Beigel F, Zitzmann K, Heeg MH, Goke B, Diepolder HM, Auernhammer CJ, Brand S
    Cytokine, 2008-01-11;41(3):209-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  394. Association of reactive oxygen and nitrogen intermediate and complement levels with apoptosis of peripheral blood mononuclear cells in lupus patients.
    Authors: Oates JC, Farrelly LW, Hofbauer AF, Wang W, Gilkeson GS
    Arthritis Rheum., 2007-11-01;56(11):3738-47.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  395. Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines.
    Authors: Qui H, Ferrell EP, Nolan N, Phelps BH, Tabibiazar R, Whitney DH, Naelfski EA
    Clin. Chem., 2007-11-01;53(11):2010-2.
    Applications: ELISA (Standard)
  396. Alpha-4/beta-1 and alpha-L/beta-2 integrins mediate cytokine induced lung leukocyte-epithelial adhesion and injury.
    Authors: Parmley LA, Elkins ND, Fini MA, Liu YE, Repine JE, Wright RM
    Br. J. Pharmacol., 2007-09-10;152(6):915-29.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  397. Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration.
    Authors: Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, Mo W, Wen D, Miatkowski K, Gonzales M, Sanicola M, Seno M, Salomon DS
    J. Biol. Chem., 2007-08-24;282(43):31643-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  398. Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis.
    Authors: Wosik K, Cayrol R, Dodelet-Devillers A, Berthelet F, Bernard M, Moumdjian R, Bouthillier A, Reudelhuber TL, Prat A
    J. Neurosci., 2007-08-22;27(34):9032-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  399. Complement receptor 3 blockade promotes IL-12-Mediated Clearance of Porphyromonas gingivalis and Negates Its Virulence In Vivo.
    Authors: Hajishengallis G, Shakhatreh MA, Wang M, Liang S
    J. Immunol., 2007-08-15;179(4):2359-67.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  400. TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells.
    Authors: Kato A, Favoreto S, Avila PC, Schleimer RP
    J. Immunol., 2007-07-15;179(2):1080-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  401. Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis.
    Authors: Facco M, Baesso I, Miorin M, Bortoli M, Cabrelle A, Boscaro E, Gurrieri C, Trentin L, Zambello R, Calabrese F, Cassatella MA, Semenzato G, Agostini C
    J. Leukoc. Biol., 2007-07-05;82(4):946-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  402. Epithelial overexpression of interleukin-32alpha in inflammatory bowel disease.
    Authors: Shioya M, Nishida A, Yagi Y, Ogawa A, Tsujikawa T, Kim-Mitsuyama S, Takayanagi A, Shimizu N, Fujiyama Y, Andoh A
    Clin. Exp. Immunol., 2007-06-22;149(3):480-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  403. Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes.
    Authors: Hundhausen C, Schulte A, Schulz B, Andrzejewski MG, Schwarz N, von Hundelshausen P, Winter U, Paliga K, Reiss K, Saftig P, Weber C, Ludwig A
    J. Immunol., 2007-06-15;178(12):8064-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  404. Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.
    Authors: Dambacher J, Beigel F, Seiderer J, Haller D, Goke B, Auernhammer CJ, Brand S
    Gut, 2007-04-20;56(9):1257-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  405. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.
    Authors: Sa SM, Valdez PA, Wu J
    J. Immunol., 2007-02-15;178(4):2229-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  406. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.
    Authors: Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM
    Blood, 2007-02-08;109(10):4272-9.
    Applications: ELISA (Standard)
  407. Prolactin enhances interferon-gamma-induced production of CXC ligand 9 (CXCL9), CXCL10, and CXCL11 in human keratinocytes.
    Authors: Kanda N, Watanabe S
    Endocrinology, 2007-01-25;148(5):2317-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  408. IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation.
    Authors: Dame TM, Orenzoff BL, Palmer LE, Furie MB
    J. Immunol., 2007-01-15;178(2):1172-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  409. Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway.
    Authors: Nagineni CN, Cherukuri KS, Kutty V, Detrick B, Hooks JJ
    J. Cell. Physiol., 2007-01-01;210(1):192-200.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  410. HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1.
    Authors: Grivel JC, Elliott J, Lisco A, Biancotto A, Condack C, Shattock RJ, McGowan I, Margolis L, Anton P
    AIDS, 2007;21(10):1263-72.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  411. Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis.
    Authors: Wan B, Nie H, Liu A, Feng G, He D, Xu R, Zhang Q, Dong C, Zhang JZ
    J. Immunol., 2006-12-15;177(12):8844-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  412. Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes.
    Authors: Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST
    J. Immunol., 2006-12-01;177(11):7665-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  413. Interleukin-11 potentiates oligodendrocyte survival and maturation, and myelin formation.
    Authors: Zhang Y, Taveggia C, Melendez-Vasquez C, Einheber S, Raine CS, Salzer JL, Brosnan CF, John GR
    J. Neurosci., 2006-11-22;26(47):12174-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  414. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
    Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
    J. Exp. Med., 2006-11-20;203(12):2763-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  415. HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
    Authors: Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J
    Glia, 2006-11-01;54(6):619-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  416. ICOS cooperates with CD28, IL-2, and IFN-gamma and modulates activation of human naive CD4+ T cells.
    Authors: Mesturini R, Nicola S, Chiocchetti A, Bernardone IS, Castelli L, Bensi T, Ferretti M, Comi C, Dong C, Rojo JM, Yagi J, Dianzani U
    Eur. J. Immunol., 2006-10-01;36(10):2601-12.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  417. Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression.
    Authors: Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L
    J. Endocrinol., 2006-10-01;191(1):65-81.
    Species: Hamster
    Sample Types: Whole Cells
    Applications: Bioassay
  418. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
    Authors: Ebert EC, Mehta V
    Cell. Immunol., 2006-08-17;241(1):7-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  419. Increased expression of Th2-associated chemokines in bullous pemphigoid disease. Role of eosinophils in the production and release of these chemokines.
    Authors: Gounni Abdelilah S, Wellemans V, Agouli M, Guenounou M, Hamid Q, Beck LA, Lamkhioued B
    Clin. Immunol., 2006-06-16;120(2):220-31.
    Applications: ELISA (Standard)
  420. IL-22 regulates the expression of genes responsible for antimicrobial defense, cellular differentiation, and mobility in keratinocytes: a potential role in psoriasis.
    Authors: Wolk K, Witte E, Wallace E, Docke WD, Kunz S, Asadullah K, Volk HD, Sterry W, Sabat R
    Eur. J. Immunol., 2006-05-01;36(5):1309-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  421. The apoptotic-cell receptor CR3, but not alphavbeta5, is a regulator of human dendritic-cell immunostimulatory function.
    Authors: Skoberne M, Somersan S, Almodovar W, Truong T, Petrova K, Henson PM, Bhardwaj N
    Blood, 2006-04-13;108(3):947-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  422. Transforming growth factor beta 1(TGF-beta1) down-regulates TNFalpha-induced RANTES production in rheumatoid synovial fibroblasts through NF-kappaB-mediated transcriptional repression.
    Authors: Cho ML, Min SY, Chang SH, Kim KW, Heo SB, Lee SH, Park SH, Cho CS, Kim HY
    Immunol. Lett., 2006-03-03;105(2):159-66.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  423. Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist.
    Authors: Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME
    J. Virol., 2005-10-01;79(20):12828-39.
    Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
    Sample Types: Whole Cells
    Applications: Bioassay
  424. Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle.
    Authors: Ameredes BT, Calhoun WJ
    J. Allergy Clin. Immunol., 2005-07-01;116(1):65-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  425. Regulation of peritoneal and systemic neutrophil-derived tumor necrosis factor-alpha release in patients with severe peritonitis: role of tumor necrosis factor-alpha converting enzyme cleavage.
    Authors: Kermarrec N, Selloum S, Plantefeve G, Chosidow D, Paoletti X, Lopez A, Mantz J, Desmonts JM, Gougerot-Pocidalo MA, Chollet-Martin S
    Crit. Care Med., 2005-06-01;33(6):1359-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  426. Ultraviolet radiation-induced injury, chemokines, and leukocyte recruitment: An amplification cycle triggering cutaneous lupus erythematosus.
    Authors: Meller S, Winterberg F, Gilliet M, Muller A, Lauceviciute I, Rieker J, Neumann NJ, Kubitza R, Gombert M, Bunemann E, Wiesner U, Franken-Kunkel P, Kanzler H, Dieu-Nosjean MC, Amara A, Ruzicka T, Lehmann P, Zlotnik A, Homey B
    Arthritis Rheum., 2005-05-01;52(5):1504-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  427. CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines.
    Authors: Dulos J, van der Vleuten MA, Kavelaars A, Heijnen CJ, Boots AM
    Arthritis Rheum., 2005-03-01;52(3):770-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  428. Expression of toll-like receptors 2 and 4 in rheumatoid synovial tissue and regulation by proinflammatory cytokines interleukin-12 and interleukin-18 via interferon-gamma.
    Authors: Radstake TR, Roelofs MF, Jenniskens YM, van Riel PL, Barrera P
    Arthritis Rheum., 2004-12-01;50(12):3856-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  429. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
    Authors: Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC
    J. Exp. Med., 2004-11-22;200(11):1419-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  430. CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure.
    Authors: Pivarcsi A, Gombert M, Dieu-Nosjean MC, Kubitza R, Meller S, Rieker J, Muller A, Da Cunha L, Haahtela A, Sonkoly E, Fridman WH, Alenius H, Kemeny L, Ruzicka T, Zlotnik A
    J. Immunol., 2004-11-01;173(9):5810-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  431. Proinflammatory mediators elicit secretion of the intracellular B-lymphocyte stimulator pool (BLyS) that is stored in activated neutrophils: implications for inflammatory diseases.
    Authors: Scapini P, Carletto A, Nardelli B, Calzetti F, Roschke V, Merigo F, Tamassia N, Pieropan S, Biasi D, Sbarbati A, Sozzani S, Bambara L, Cassatella MA
    Blood, 2004-09-09;105(2):830-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  432. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.
    Authors: Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R
    J. Immunol., 2004-09-01;173(5):3482-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  433. IL-22 increases the innate immunity of tissues.
    Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
    Immunity, 2004-08-01;21(2):241-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  434. Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor.
    Authors: Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM
    Biochem. J., 2004-06-01;380(0):425-33.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  435. Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
    Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
    Blood, 2004-03-25;104(2):314-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  436. TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia.
    Authors: Ryan LA, Peng H, Erichsen DA, Huang Y, Persidsky Y, Zhou Y, Gendelman HE, Zheng J
    J. Neuroimmunol., 2004-03-01;148(1):127-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  437. Interferon-gamma inhibits transforming growth factor-beta production in human airway epithelial cells by targeting Smads.
    Authors: Wen FQ, Liu X, Kobayashi T, Abe S, Fang Q, Kohyama T, Ertl R, Terasaki Y, Manouilova L, Rennard SI
    Am. J. Respir. Cell Mol. Biol., 2004-01-12;30(6):816-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  438. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
    Authors: Copeland S, Siddiqui J, Remick D
    J. Immunol. Methods, 2004-01-01;284(1):99-106.
    Applications: ELISA (Standard)
  439. High-affinity autoantibodies specifically eliminate granulocyte-macrophage colony-stimulating factor activity in the lungs of patients with idiopathic pulmonary alveolar proteinosis.
    Authors: Uchida K, Nakata K, Trapnell BC, Terakawa T, Hamano E, Mikami A, Matsushita I, Seymour JF, Oh-Eda M, Ishige I, Eishi Y, Kitamura T, Yamada Y, Hanaoka K, Keicho N
    Blood, 2003-09-25;103(3):1089-98.
    Species: Human
    Sample Types:
    Applications: Binding Assay
  440. Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation.
    Authors: McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N
    J. Clin. Invest., 2003-08-01;112(4):598-607.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  441. In human B cells, IL-12 triggers a cascade of molecular events similar to Th1 commitment.
    Authors: Durali D, de Goer de Herve MG, Giron-Michel J, Azzarone B, Delfraissy JF, Taoufik Y
    Blood, 2003-07-31;102(12):4084-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  442. The human anti-CD30 antibody 5F11 shows in vitro and in vivo activity against malignant lymphoma.
    Authors: Borchmann P, Treml JF, Hansen H, Gottstein C, Schnell R, Staak O, Zhang HF, Davis T, Keler T, Diehl V, Graziano RF, Engert A
    Blood, 2003-07-24;102(10):3737-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  443. Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis.
    Authors: Groh V, Bruhl A, El-Gabalawy H, Nelson JL, Spies T
    Proc. Natl. Acad. Sci. U.S.A., 2003-07-23;100(16):9452-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  444. HIV-1 protein Vpr suppresses IL-12 production from human monocytes by enhancing glucocorticoid action: potential implications of Vpr coactivator activity for the innate and cellular immunity deficits observed in HIV-1 infection.
    Authors: Mirani M, Elenkov I, Volpi S, Hiroi N, Chrousos GP, Kino T
    J. Immunol., 2002-12-01;169(11):6361-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  445. Expression of CTLA-4 by human monocytes.
    Authors: Wang XB, Giscombe R, Yan Z
    Scand. J. Immunol., 2002-01-01;55(1):53-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  446. Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver.
    Authors: Barcena A, Park SW, Banapour B, Muench MO, Mechetner E
    Blood, 1996-09-15;88(6):2013-25.
    Species: Human
    Sample Types:
    Applications: Bioassay

FAQs

  1. Why does Recombinant Human IFN-gamma protein, Catalog # 285-IF, have the amio acid substitution R160Q?

    • The sequence of R&D Systems' rhIFN-gamma, Catalog # 285-IF,  is based on the the following publication in Nature:[https://www.ncbi.nlm.nih.gov/pubmed/?term=Gray+1982+503] Note that in figure 3, the article describes a Gln (Q) in position 160.

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Reviews for Recombinant Human IFN-gamma Protein

Average Rating: 4.6 (Based on 23 Reviews)

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Recombinant Human IFN-gamma Protein
By Lana Jagannathan on 08/26/2024
Application: Stem/Immune cell maintenance or differentiation
Reason for Rating: We use this cytokine to produce a maturation response in dendritic cells and have had consistent success over the years in inducing this maturation using R&D IFN-g.

Recombinant Human IFN-gamma Protein
By Anonymous on 06/24/2022
Application: Flow

Black -> HLA-E surface expression in T cells
Grey -> HLA-E surface expression in T cells upon IFNg stimulation (12h)


Recombinant Human IFN-gamma Protein
By Anonymous on 06/24/2022
Application: In vitro bioactivity in cell culture
Reason for Rating: Comparing gene expression responses by qPCR after IFNg treatment in immune cell subsets

More than a hundred-fold increase for a given target gene in immune cells stimulated with IFNg for 6h compared to controls (for basal level).


Recombinant Human IFN-gamma Protein
By Anonymous on 06/24/2022

Reason for Rating: Used for successfully stimulating human PBMCs.

Lane 1: PBMCs, unstimulated
Lane 2: PBMCs, stimulated with IFNg for 6h
Lane 3: PBMCs, stimulated with IFNg for 24h

Target: HLA detection


Recombinant Human IFN-gamma Protein
By Anonymous on 05/21/2021
Application: In vitro bioactivity in cell culture

Recombinant Human IFN-gamma Protein
By Marija Pieper on 03/11/2021
Application: Apoptosis assay

Recombinant Human IFN-gamma Protein
By Anonymous on 12/18/2020

Recombinant Human IFN-gamma Protein
By Anonymous on 11/20/2020
Application: Stem/Immune cell maintenance or differentiation
Reason for Rating: Gave consistent M1-like macrophage differentiation of human PBMCs

Recombinant Human IFN-gamma Protein
By Anonymous on 10/16/2020
Application: In vitro bioactivity in cell culture
Reason for Rating: Easy to solubilize

Used the to stimulate ex vivo skin culture


Recombinant Human IFN-gamma Protein
By Anonymous on 10/09/2020
Application: In vitro bioactivity in cell culture

HCT-116 cells were treated with hr-IFN-gamma for 24 hours and intracellular IDO-1 expression was measured.


Recombinant Human IFN-gamma Protein
By Anonymous on 06/08/2020
Application: In vitro bioactivity in cell culture

Recombinant Human IFN-gamma Protein
By Anonymous on 06/06/2020
Application: In vitro bioactivity in cell culture

Recombinant Human IFN-gamma Protein
By Anonymous on 07/26/2019
Application: CellProlif

Recombinant Human IFN-gamma Protein
By Anonymous on 07/25/2019
Application: In vitro bioactivity in cell culture
Reason for Rating: Consistent results when used for in vitro cell culture

CD38 transcript levels measured by qPCR after 24 hours treatment with 10 ng/mL IFN-g in MV-4-11 cells


Recombinant Human IFN-gamma Protein
By Anonymous on 06/09/2019
Application: In vitro bioactivity in cell culture
Reason for Rating: The expression of HLA-DR increased with MDAMB231 cells incubated with 1000 IU mL–1 IFN-gamma for 72 h

Recombinant Human IFN-gamma Protein
By Mehdi Alavi on 03/19/2019
Application: Enzymatic activity in vitro

Recombinant Human IFN-gamma Protein
By Anonymous on 11/16/2018
Application: CellProlif
Reason for Rating: HT-29 Cell lines were treated with 100 U/ml IFN gamma, after which HLA-DR expression was examined by flow cytometer

Recombinant Human IFN-gamma Protein
By Anonymous on 10/08/2018
Application: In vitro bioactivity in cell culture

Recombinant Human IFN-gamma Protein
By Pia Muyot on 04/26/2017

Recombinant Human IFN-gamma Protein
By Anonymous on 07/21/2016
Application: In vitro bioactivity in cell culture
Reason for Rating: The IFN-g was excellent in stimulating whole blood.

IFN-g was used to stimulate whole blood. 100ng/mL final concentration was used in 1mL whole blood for 15 minutes at 37C. The cells were fixed and stored in -80C until further analysis on CyTOF


Recombinant Human IFN-gamma Protein
By Adam Guess on 07/13/2016
Application: In vivo study

IFN-gamma treatment (solid line) induces HLA-DR expression in cultured MSC as compared to control cells (filled histogram).


Recombinant Human IFN-gamma Protein
By shu wang on 05/31/2016
Application: In vitro bioactivity in cell culture

Recombinant Human IFN-gamma Protein
By SOjan Abraham on 01/21/2016
Application: In vitro bioactivity in cell culture