Recombinant Cotton Rat CD8 alpha Protein, CF Summary
Product Specifications
Ser24-Asp182, with a C-terninal 6-His tag
Analysis
Product Datasheets
Carrier Free
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
9648-CD
Formulation | Lyophilized from a 0.2 μm filtered solution in PBS. |
Reconstitution | Reconstitute at 250 μg/mL in PBS. |
Shipping | The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. |
Reconstitution Calculator
Background: CD8
CD8 is a dimeric complex made up of two Ig superfamily members (1). The CD8 alpha chain is a type I transmembrane glycoprotein that can dimerize either with itself forming CD8 alpha alpha, or with a 30-35 kDa CD8 beta chain, forming CD8 alpha beta (2). CD8 alpha contains one V-type Ig-like domain in its extracellular region that binds to class I MHC molecules. CD8 alpha beta is a TCR co-receptor, while CD8 alpha alpha promotes T cell survival and differentiation (1, 3). The mature cotton rat CD8 alpha consists of a 159 amino acid (aa) extracellular domain (ECD), and runs at ~30 kDa under reduced condition. Within the ECD, cotton rat CD8 alpha shares 49%, 47%, and 54% amino acid sequence identity with human, mouse, and rat CD8 alpha, respectively.
- Laugel, B. et al. (2011) J. Leukoc. Biol. 90:1089.
- Snow, P.M. and C. Terhorst (1983) J. Biol. Chem. 258:14675.
- Cole, D.K. et al. (2012) Immunology 137:139.
FAQs
No product specific FAQs exist for this product, however you may
View all Proteins and Enzyme FAQsReviews for Recombinant Cotton Rat CD8 alpha Protein, CF
Average Rating: 5 (Based on 1 Review)
Have you used Recombinant Cotton Rat CD8 alpha Protein, CF?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥2500 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Filter by: