Rat TNF-alpha Quantikine ELISA Kit Summary
Product Summary
Precision
Cell Culture Supernates, Serum, EDTA Plasma, Heparin Plasma
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 20 | 20 | 20 |
Mean (pg/mL) | 65 | 232 | 593 | 63 | 246 | 656 |
Standard Deviation | 3.3 | 5.1 | 12.5 | 6.1 | 23.6 | 57.6 |
CV% | 5.1 | 2.2 | 2.1 | 9.7 | 9.6 | 8.8 |
Recovery
The recovery of rat TNF-alpha spiked to three levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Supernates (n=6) | 101 | 93-119 |
EDTA Plasma (n=5) | 96 | 88-104 |
Heparin Plasma (n=4) | 80 | 73-84 |
Serum (n=8) | 93 | 83-105 |
Linearity
Scientific Data
Product Datasheets
Preparation and Storage
Background: TNF-alpha
Tumor necrosis factor alpha (TNF-alpha ), also known as cachectin and TNFSF1A, is the prototypic ligand of the TNF superfamily (1). It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism (2-5). TNF-alpha is also involved in a number of pathological conditions including asthma, Crohn's disease, rheumatoid arthritis, neuropathic pain, obesity, type 2 diabetes, septic shock, autoimmunity, and cancer (5-11).
Assay Procedure
Refer to the product- Prepare all reagents, standard dilutions, and samples as directed in the product insert.
- Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
- Add 50 µL of Assay Diluent to each well.
- Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
- Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.
- Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
- Aspirate and wash 5 times.
- Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
- Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations for Rat TNF-alpha Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Development of a proliposomal pretomanid dry powder inhaler as a novel alternative approach for combating pulmonary tuberculosis
Authors: Aekwattanaphol, N;Das, SC;Khadka, P;Nakpheng, T;Ali Khumaini Mudhar Bintang, M;Srichana, T;
International journal of pharmaceutics
Species: Rat
Sample Types: Cell Culture Supernates
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New Insights into Hepatic and Intestinal Microcirculation and Pulmonary Inflammation in a Model of Septic Shock and Venovenous Extracorporeal Membrane Oxygenation in the Rat
Authors: Edinger, F;Zajonz, T;Holtz, L;Schmidt, G;Schneck, E;Sander, M;Koch, C;
International journal of molecular sciences
Species: Rat
Sample Types: Plasma, BALF
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Geranylgeranylacetone mitigates sepsis-associated intestinal injury through CHIP-dependent anti-inflammation and anti-oxidative effect
Authors: Liu, X;Liu, Y;Su, X;Jiang, L;Tang, G;Wang, Y;
International immunopharmacology
Species: Rat
Sample Types: Cell Culture Supernates
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Asiatic acid rescues intestinal tissue by suppressing molecular, biochemical, and histopathological changes associated with the development of ulcerative colitis
Authors: Lokman, MS;Kassab, R;Salem, FAM;Elshopakey, GE;Hussein, A;Aldarmahi, AA;Theyab, A;Alzahrani, KJ;Hassan, KE;Alsharif, KF;Albrakati, A;Tayyeb, JZ;El-Khadragy, MF;Alkhateeb, MA;Al-Ghamdy, AO;Althagafi, HA;Abdel Moneim, A;El-Hennamy, RE;
Bioscience reports
Species: Rat
Sample Types: Tissue Homogenates
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Neuroprotective effects of a novel peptide through the Rho-integrin-Tie2 and PI3K/Akt pathways in experimental autoimmune encephalomyelitis model
Authors: Zhou, W;Qu, H;Fu, XX;Xu, MM;Li, Q;Jiang, Y;Han, S;
Frontiers in pharmacology
Species: Rat
Sample Types: Plasma
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Impact of Bariatric Surgery on ABC Subtilisin/Kexin Type 9 (PCSK9) Gene Expression and Inflammation in the Adipose Tissue of Obese Diabetic Rats
Authors: Heald, AH;Fachim, HA;Bashir, B;Garside, B;Adam, S;Iqbal, Z;Syed, AA;Donn, R;Le Roux, CW;Abdelaal, M;White, J;Soran, H;
International journal of molecular sciences
Species: Rat
Sample Types: Tissue Homogenates
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Experimental evidence of the neurotoxic effect of monosodium glutamate in adult female Sprague Dawley rats: The potential protective role of Zingiber officinale Rosc. rhizomes
Authors: El-Hashash, SA;El-Sakhawy, MA;Eldamaty, HSE;Alqasem, AA;
Saudi journal of biological sciences
Species: Rat
Sample Types: Tissue Homogenates
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A novel modified-curcumin 2.24 resolves inflammation by promoting M2 macrophage polarization
Authors: Deng, J;Golub, LM;Lee, HM;Bhatt, HD;Johnson, F;Xu, TM;Gu, Y;
Scientific reports
Species: Rat
Sample Types: Cell Culture Supernates
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Melatonin Alleviates Intestinal Barrier Damaging Effects Induced by Polyethylene Microplastics in Albino Rats
Authors: El Gazzar, WB;Sliem, RE;Bayoumi, H;Nasr, HE;Shabanah, M;Elalfy, A;Radwaan, SE;Gebba, MA;Mansour, HM;Badr, AM;Amer, MF;Ashour, SS;Morsi, H;Aboelkomsan, ESAF;Baioumy, B;Sayed, AEH;Farag, AA;
International journal of molecular sciences
Species: Rat
Sample Types: Cell Culture Supernates
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Allicin protects against LPS-induced cardiomyocyte injury by activating Nrf2-HO-1 and inhibiting NLRP3 pathways
Authors: Sun, F;Xu, K;Zhou, J;Zhang, W;Duan, G;Lei, M;
BMC cardiovascular disorders
Species: Rat
Sample Types: Cell Culture Supernates
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The protective effects of sesamol and/or the probiotic, Lactobacillus rhamnosus, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/?-catenin/GSK-3?, JAK-2/STAT-3, PPAR-?, inflammatory, and apoptotic pathways
Authors: Abu-Elfotuh, K;Selim, HMRM;Riad, OKM;Hamdan, AME;Hassanin, SO;Sharif, AF;Moustafa, NM;Gowifel, AMH;Mohamed, MYA;Atwa, AM;Zaghlool, SS;El-Din, MN;
Frontiers in pharmacology
Species: Rat
Sample Types: Tissue Homogenates
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Hydrogen alleviated cognitive impairment and blood‒brain barrier damage in sepsis-associated encephalopathy by regulating ABC efflux transporters in a PPAR alpha -dependent manner
Authors: Bai, Y;Mi, W;Meng, X;Dong, B;Jiang, Y;Lu, Y;Yu, Y;
BMC neuroscience
Species: Mouse
Sample Types: Tissue Homogenates
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Therapeutic Effect of Enzymatically Hydrolyzed Cervi Cornu Collagen NP-2007 and Potential for Application in Osteoarthritis Treatment
Authors: Kim, HR;Lee, SH;Noh, EM;Choi, B;Seo, HY;Jang, H;Kim, SY;Park, MH;
International journal of molecular sciences
Species: Rat
Sample Types: Cell Culture Supernates, Serum
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Vinpocetine alleviates intestinal ischemia/reperfusion injury and enhances M2 macrophage polarization in rats: Role of SIRT1/SOCS3/STAT3 signaling pathway
Authors: Elwany, NE;Abdelhamid, AM;Mohamed, NM;Khalil, SS;Elsayed Orabi, EE;Abdelfattah, AM;
International immunopharmacology
Species: Rat
Sample Types: Tissue Homogenates
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Experimental Liver Cirrhosis Inhibits Restenosis after Balloon Angioplasty
Authors: Mechelinck, M;Hein, M;Kupp, C;Braunschweig, T;Helmedag, MJ;Klinkenberg, A;Habigt, MA;Klinge, U;Tolba, RH;Uhlig, M;
International journal of molecular sciences
Species: Rat
Sample Types: Serum
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Efficacy of Carotenoid-Loaded Gelatin Nanoparticles in Reducing Plasma Cytokines and Adipocyte Hypertrophy in Wistar Rats
Authors: Queiroz, JLC;Medeiros, I;Lima, MSR;Carvalho, FMC;Camillo, CS;Santos, PPA;Guerra, GCB;da Silva, VC;Schroeder, HT;Krause, M;Morais, AHA;Passos, TS;
International journal of molecular sciences
Species: Rat
Sample Types: Plasma, Tissue Homogenates
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Aqueous cannabidiol ?-cyclodextrin complexed polymeric micelle nasal spray to attenuate in vitro and ex vivo SARS-CoV-2-induced cytokine storms
Authors: Changsan, N;Sawatdee, S;Suedee, R;Chunhachaichana, C;Srichana, T;
International journal of pharmaceutics
Species: Mouse
Sample Types: Cell Culture Supernates
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Microglial synaptic pruning in the nucleus accumbens during adolescence sex-specifically influences splenic immune outcomes
Authors: Kirkland, JM;Patel, I;Ardeshna, MS;Kopec, AM;
bioRxiv : the preprint server for biology
Species: Rat
Sample Types: Tissue Homogenates
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Natural antioxidant formula ameliorates lipopolysaccharide-induced impairment of hippocampal neurogenesis and contextual fear memory through suppression of neuroinflammation in rats
Authors: Zeng, W;Takashima, K;Tang, Q;Zou, X;Ojiro, R;Ozawa, S;Jin, M;Ando, Y;Yoshida, T;Shibutani, M;
Journal of chemical neuroanatomy
Species: Rat
Sample Types: Tissue Homogenates
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Cirrhotic Cardiomyopathy Following Bile Duct Ligation in Rats-A Matter of Time?
Authors: Uhlig, M;Hein, M;Habigt, MA;Tolba, RH;Braunschweig, T;Helmedag, MJ;Arici, M;Thei�en, A;Klinkenberg, A;Klinge, U;Mechelinck, M;
International journal of molecular sciences
Species: Rat
Sample Types: Serum
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Assessing the hepatoprotective effects of hesperidin on liver-associated disorders in albino rats with experimentally induced obesity and type II diabetes: A histological and biochemical study
Authors: Atta, IS;Elnady, MR;Alghamdi, AG;Alghamdi, AH;Aboulata, AA;Shatla, IM;
Heliyon
Species: Rat
Sample Types: Tissue Homogenates
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Ameliorative effect of cheqianzi decoction on hyperuricemia and kidney injury and underlying mechanism in rats
Authors: J Meng, J Tian, Y Zhao, C Li, Y Yi, Y Zhang, J Han, L Wang, C Pan, S Liu, C Liu, F Wang, X Tang, D Wang, S Qin, A Liang
Heliyon, 2023-04-11;9(4):e15333.
Species: Rat
Sample Types: Tissue Homogenates
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Supplementation with okra�combined or not with exercise training is able to protect the heart of animals with metabolic syndrome
Authors: MFP Gomes, EOC de Moura, NM Cardoso, GA da Silva, ACC Dos Santos, FS de Souza, D Estadella, RH Lambertucc, JHG Lago, A Medeiros
Scientific Reports, 2023-01-26;13(1):1468.
Species: Rat
Sample Types: Tissue Homogenates
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Yiyi Fuzi Baijiang Powder Alleviates Dextran Sulfate Sodium-Induced Ulcerative Colitis in Rats via Inhibiting the TLR4/NF-kappaB/NLRP3 Inflammasome Signaling Pathway to Repair the Intestinal Epithelial Barrier, and Modulating Intestinal Microbiota
Authors: J Yang, L Miao, Y Xue, X Wang
Oxidative Medicine and Cellular Longevity, 2023-01-14;2023(0):3071610.
Species: Rat
Sample Types: Tissue Homogenates
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Ameliorative effect of cheqianzi decoction on hyperuricemia and kidney injury and underlying mechanism in rats
Authors: J Meng, J Tian, Y Zhao, C Li, Y Yi, Y Zhang, J Han, L Wang, C Pan, S Liu, C Liu, F Wang, X Tang, D Wang, S Qin, A Liang
Heliyon, 2023;9(4):e15333.
Species: Rat
Sample Types: Tissue Homogenates
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Lactate attenuates astrocytic inflammation by inhibiting ubiquitination and degradation of NDRG2 under oxygen-glucose deprivation conditions
Authors: J Xu, T Ji, G Li, H Zhang, Y Zheng, M Li, J Ma, Y Li, G Chi
Journal of Neuroinflammation, 2022-12-26;19(1):314.
Species: Rat
Sample Types: Cell Culture Supernates
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Acute postoperative pain and dorsal root ganglia transcriptomic signatures following total knee arthroplasty (TKA) in rats: An experimental study
Authors: DE Komatsu, SMZ Uddin, C Gordon, MP Kanjiya, D Bogdan, J Achonu, A DiBua, H Iftikhar, A Ackermann, RJ Shah, J Shieh, AB Bialkowska, M Kaczocha
PLoS ONE, 2022-12-06;17(12):e0278632.
Species: Rat
Sample Types: Serum
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A Comparative Study of Two Models of Intraluminal Filament Middle Cerebral Artery Occlusion in Rats: Long-Lasting Accumulation of Corticosterone and Interleukins in the Hippocampus and Frontal Cortex in Koizumi Model
Authors: MV Onufriev, MY Stepaniche, YV Moiseeva, MY Zhanina, OA Nedogreeva, PA Kostryukov, NA Lazareva, NV Gulyaeva
Biomedicines, 2022-12-02;10(12):.
Species: Rat
Sample Types: Serum
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Black Garlic and Thiosulfinate-Enriched Extracts as Adjuvants to Ceftriaxone Treatment in a Rat Peritonitis Model of Sepsis
Authors: FJ Redondo-Ca, N Bejarano-R, V Baladrón, O Montenegro, LA Gómez, R Velasco, N Villasanti, S Illescas, MT Franco-Ser, I Gracia, JF Rodríguez, JR Muñoz-Rodr, JM Pérez-Orti
Biomedicines, 2022-12-01;10(12):.
Species: Rat
Sample Types: Serum
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Reducing brain TACE activity improves neuroinflammation and cardiac function in heart failure rats
Authors: Y Yu, B Xue, NM Irfan, T Beltz, RM Weiss, AK Johnson, RB Felder, SG Wei
Frontiers in Physiology, 2022-11-09;13(0):1052304.
Species: Rat
Sample Types: CSF
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Anti-Inflammatory Protein Isolated from Tamarind Promotes Better Histological Aspects in the Intestine Regardless of the Improvement of Intestinal Permeability in a Preclinical Study of Diet-Induced Obesity
Authors: MSR Lima, C Gonçalves, MD Neto, MH Macedo, JLC Queiroz, VC da Silva, IS Costa, CDS Camillo, PPA Santos, AAM Lima, L Pastrana, BLL Maciel, AHA Morais
Nutrients, 2022-11-04;14(21):.
Species: Rat
Sample Types: Plasma
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MicroRNA-25-5p negatively regulates TXNIP expression and relieves inflammatory responses of brain induced by lipopolysaccharide
Authors: J Wang, Z Ye, Y Chen, X Qiao, Y Jin
Scientific Reports, 2022-10-26;12(1):17915.
Species: Rat
Sample Types: Plasma
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DUSP8/TAK1 signaling mediates neuropathic pain through regulating neuroinflammation and neuron death in a spinal nerve ligation (SNL) rat model
Authors: C Liao, H Zhou, H Chen, G Cheng, S Li, F Ma, X Yang, B Xie, W Zhang
International immunopharmacology, 2022-10-21;113(0):109284.
Species: Rat
Sample Types: Cell Culture Supernates
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Sacubitril/valsartan (LCZ696) ameliorates hyperthyroid-induced cardiac hypertrophy in male rats through modulation of miR-377, let-7 b, autophagy, and fibrotic signaling pathways
Authors: T Khamis, AE Alsemeh, DM Abdullah
Scientific Reports, 2022-08-27;12(1):14654.
Species: Rat
Sample Types: Serum
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Rhabdomyolysis-induced acute kidney injury and concomitant apoptosis induction via ROS-mediated ER stress is efficaciously counteracted by epigallocatechin gallate
Authors: SN Chang, M Haroon, DK Dey, SC Kang
The Journal of nutritional biochemistry, 2022-08-24;0(0):109134.
Species: Rat
Sample Types: Tissue Homogenates
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Anti-inflammatory clearance of amyloid-beta by a chimeric Gas6 fusion protein
Authors: H Jung, SY Lee, S Lim, HR Choi, Y Choi, M Kim, S Kim, Y Lee, KH Han, WS Chung, CH Kim
Nature Medicine, 2022-08-04;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
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Transient neuroinflammation following surgery contributes to long-lasting cognitive decline in elderly rats via dysfunction of synaptic NMDA receptor
Authors: B Chen, G Qin, J Xiao, X Deng, A Lin, H Liu
Journal of Neuroinflammation, 2022-07-13;19(1):181.
Species: Rat
Sample Types: Serum
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Neuroprotective Effect of Bcl-2 on Lipopolysaccharide-Induced Neuroinflammation in Cortical Neural Stem Cells
Authors: SY Park, JS Han
International Journal of Molecular Sciences, 2022-06-07;23(12):.
Species: Rat
Sample Types: Cell Culture Supernates
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Aerobic exercise training combined or not with okra consumption as a strategy to prevent kidney changes caused by metabolic syndrome in Zucker rats
Authors: MM da Silva, MFP Gomes, EOC de Moura, MM Veras, MC Kubota, AP Takano, ACC Dos Santos, CGDR José, GADS Souza, NM Cardoso, D Estadella, RH Lambertucc, A Medeiros
PLoS ONE, 2022-06-03;17(6):e0269418.
Species: Rat
Sample Types: Tissue Homogenates
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Melatonin and zinc supplements with physical and mental activities subside neurodegeneration and hepatorenal injury induced by aluminum chloride in rats: Inclusion of GSK-3beta-Wnt/beta-catenin signaling pathway
Authors: K Abu-Elfotu, FH Hussein, AN Abbas, MD Al-Rekabi, SS Barghash, SS Zaghlool, SZ El-Emam
Neurotoxicology, 2022-05-05;91(0):69-83.
Species: Rat
Sample Types: Tissue Homogenates
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H3K9me2 regulation of BDNF expression via G9a partakes in the progression of heart failure
Authors: F Yan, Z Chen, W Cui
BMC cardiovascular disorders, 2022-04-19;22(1):182.
Species: Rat
Sample Types: Serum
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PPARalpha contributes to the therapeutic effect of hydrogen gas against sepsis-associated encephalopathy with the regulation to the CREB-BDNF signaling pathway and hippocampal neuron plasticity-related gene expression
Authors: Y Bai, Q Han, B Dong, H Lin, Y Jiang, X Zhang, H Chen, Y Yu
Brain research bulletin, 2022-03-30;184(0):56-67.
Species: Mouse
Sample Types: Tissue Homogenates
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Piceatannol suppresses inflammation and promotes apoptosis in rheumatoid arthritis?fibroblast?like synoviocytes by inhibiting the NF?kappaB and MAPK signaling pathways
Authors: X Gao, X Kang, H Lu, E Xue, R Chen, J Pan, J Ma
Molecular Medicine Reports, 2022-03-24;25(5):.
Species: Rat
Sample Types: Serum
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Vitamin C Improves the Outcomes of Cardiopulmonary Resuscitation and Alters Shedding of Syndecan-1 and p38/MAPK Phosphorylation in a Rat Model
Authors: Y Xiao, C Su, G Zhang, L Liang, T Jin, J Bradley, JP Ornato, W Tang
Journal of the American Heart Association, 2022-03-15;0(0):e023787.
Species: Rat
Sample Types: Serum
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Repeated glucose spikes and insulin resistance synergistically deteriorate endothelial function and bardoxolone methyl ameliorates endothelial dysfunction
Authors: K Ogiso, SC Shayo, S Kawade, H Hashiguchi, T Deguchi, Y Nishio
PLoS ONE, 2022-01-24;17(1):e0263080.
Species: Rat
Sample Types: Serum
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Targeting inflammation, autophagy, and apoptosis by troxerutin attenuates methotrexate-induced renal injury in rats
Authors: HH Arab, SA Abd El-Aal, AH Eid, EA Arafa, AM Mahmoud, AM Ashour
International immunopharmacology, 2021-12-23;103(0):108284.
Species: Rat
Sample Types: Tissue Homogenates
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A Comparative Study of Koizumi and Longa Methods of Intraluminal Filament Middle Cerebral Artery Occlusion in Rats: Early Corticosterone and Inflammatory Response in the Hippocampus and Frontal Cortex
Authors: MV Onufriev, YV Moiseeva, MY Zhanina, NA Lazareva, NV Gulyaeva
International Journal of Molecular Sciences, 2021-12-17;22(24):.
Species: Rat
Sample Types: Serum
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Essential Fatty Acids and Their Metabolites in the Pathobiology of Inflammation and Its Resolution
Authors: UN Das
Biomolecules, 2021-12-14;11(12):.
Species: Rat
Sample Types: Plasma
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Study of the Role of the Tyrosine Kinase Receptor MerTK in the Development of Kidney Ischemia-Reperfusion Injury in RCS Rats
Authors: T Pelé, S Giraud, S Joffrion, V Ameteau, A Delwail, JM Goujon, L Macchi, T Hauet, F Dkhissi, O Benzakour
International Journal of Molecular Sciences, 2021-11-09;22(22):.
Species: Rat
Sample Types: Plasma
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Protective effects of endothelial progenitor cell microvesicles on Ang�II?induced rat kidney cell injury
Authors: Y Song, Z Bai, Y Zhang, J Chen, M Chen, Y Zhang, X Zhang, H Mai, B Wang, Y Lin, S Gu
Molecular Medicine Reports, 2021-11-05;25(1):.
Species: Rat
Sample Types: Cell Culture Supernates
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Endogenous tRNA-derived small RNA (tRF3-Thr-AGT) inhibits ZBP1/NLRP3 pathway-mediated cell pyroptosis to attenuate acute pancreatitis (AP)
Authors: B Sun, Z Chen, Q Chi, Y Zhang, B Gao
Journal of Cellular and Molecular Medicine, 2021-10-13;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
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Loganin Ameliorates Painful Diabetic Neuropathy by Modulating Oxidative Stress, Inflammation and Insulin Sensitivity in Streptozotocin-Nicotinamide-Induced Diabetic Rats
Authors: YC Cheng, YM Chiu, ZK Dai, BN Wu
Cells, 2021-10-08;10(10):.
Species: Rat
Sample Types: Plasma
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Renoprotection Induced by Aerobic Training Is Dependent on Nitric Oxide Bioavailability in Obese Zucker Rats
Authors: RVP Neves, HL Corrêa, IV de Sousa N, MK Souza, F Costa, AS Haro, LA Deus, AL Reis, HG Simões, RV Andrade, CO Assumpção, W Stone, J Prestes, EC Vieira, R de Cássia, V Cruzat, TS Rosa
Oxidative Medicine and Cellular Longevity, 2021-09-28;2021(0):3683796.
Species: Rat
Sample Types: Tissue Homogenates
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Hydrogen Sulfide Reduces Ischemia and Reperfusion Injury in Neuronal Cells in a Dose- and Time-Dependent Manner
Authors: S Scheid, M Goeller, W Baar, J Wollborn, H Buerkle, G Schlunck, W Lagrèze, U Goebel, F Ulbrich
International Journal of Molecular Sciences, 2021-09-18;22(18):.
Species: Rat
Sample Types: Serum
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Intervention of Gastrodin in Type 2 Diabetes Mellitus and Its Mechanism
Authors: Y Bai, K Mo, G Wang, W Chen, W Zhang, Y Guo, Z Sun
Frontiers in Pharmacology, 2021-09-16;12(0):710722.
Species: Rat
Sample Types: Serum
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Balance of Drug Residence and Diffusion in Lacrimal Fluid Determine Ocular Bioavailability in In Situ Gels Incorporating Tranilast Nanoparticles
Authors: M Minami, H Otake, Y Nakazawa, N Okamoto, N Yamamoto, H Sasaki, N Nagai
Pharmaceutics, 2021-09-08;13(9):.
Species: Rat
Sample Types: Tissue Homogenates
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GPER and IGF-1R mediate the anti-inflammatory effect of genistein against lipopolysaccharide (LPS)-induced nigrostriatal injury in rats
Authors: ZR Du, Y Gu, XM Xie, M Zhang, GY Jiang, WF Chen
The Journal of steroid biochemistry and molecular biology, 2021-08-31;214(0):105989.
Species: Rat
Sample Types: Tissue Homogenates
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Acute myocardial injury secondary to severe acute liver failure: A retrospective analysis supported by animal data
Authors: M Uhlig, M Hein, MA Habigt, RH Tolba, T Braunschwe, MJ Helmedag, U Klinge, A Koch, C Trautwein, M Mechelinck
PLoS ONE, 2021-08-30;16(8):e0256790.
Species: Rat
Sample Types: Plasma
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Acute Inflammatory Response in Osteoporotic Fracture Healing Augmented with Mechanical Stimulation is Regulated In Vivo through the p38-MAPK Pathway
Authors: SKH Chow, C Cui, KYK Cheng, YN Chim, J Wang, CHW Wong, KW Ng, RMY Wong, WH Cheung
International Journal of Molecular Sciences, 2021-08-13;22(16):.
Species: Rat
Sample Types: Serum
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Suppression of Inflammation-Associated Kidney Damage Post-Transplant Using the New PrC-210 Free Radical Scavenger in Rats
Authors: TR Goesch, NA Wilson, W Zeng, BM Verhoven, W Zhong, MM Coumbe Git, WE Fahl
Biomolecules, 2021-07-19;11(7):.
Species: Rat
Sample Types: Plasma
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L. Cucurbita pepo Alleviates Chronic Unpredictable Mild Stress via Modulation of Apoptosis, Neurogenesis, and Gliosis in Rat Hippocampus
Authors: N Ayuob, SA Shaker, E Hawuit, NS Al-Abbas, NA Shaer, S Al Jaouni, MR Mahdi
Oxidative Medicine and Cellular Longevity, 2021-07-10;2021(0):6662649.
Species: Rat
Sample Types: Serum
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Can selenium-enriched spirulina supplementation ameliorate sepsis outcomes in selenium-deficient animals?
Authors: T Castel, M Theron, K Pichavant-, A Guernec, A Joublin-De, B Gueguen, K Leon
Physiological Reports, 2021-07-01;9(14):e14933.
Species: Rat
Sample Types: Plasma
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Prenatal Hyperhomocysteinemia Induces Glial Activation and Alters Neuroinflammatory Marker Expression in Infant Rat Hippocampus
Authors: AD Shcherbits, DS Vasilev, YP Milyutina, NL Tumanova, AV Mikhel, IV Zalozniaia, AV Arutjunyan
Cells, 2021-06-18;10(6):.
Species: Rat
Sample Types: Tissue Homogenates
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Co-infection by Salmonella enterica subsp. Enterica serovar typhimurium and Entamoeba dispar pathogenic strains enhances colitis and the expression of amoebic virulence factors
Authors: FM Silva Oliv, A Claúdia de, S Henrique d, LO Prata, MA Junior, CA Vilela da, GH Campolina-, M Lorenzo de, CA Oliveira, E Neumann, ÁC Nunes, MA Gomes, MV Caliari
Microbial pathogenesis, 2021-06-12;158(0):105010.
Species: Rat
Sample Types: Plasma
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Down-regulation of SNHG16 alleviates the acute lung injury in sepsis rats through miR-128-3p/HMGB3 axis
Authors: J Sun, K Xin, C Leng, J Ge
BMC pulmonary medicine, 2021-06-06;21(1):191.
Species: Rat
Sample Types: Tissue Homogenates
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Neuroprotective Effects of VEGF-A Nanofiber Membrane and FAAH Inhibitor URB597 Against Oxygen-Glucose Deprivation-Induced Ischemic Neuronal Injury
Authors: DP Wang, KY Jin, P Zhao, Q Lin, K Kang, J Hai
International Journal of Nanomedicine, 2021-05-27;16(0):3661-3678.
Species: Rat
Sample Types: Cell Culture Supernates
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MiR-128-3p alleviates TNBS-induced colitis through inactivating TRAF6/NF-&kappaB signaling pathway in rats
Authors: LL Huo, ZR Sun
The Kaohsiung journal of medical sciences, 2021-05-27;0(0):.
Species: Rat
Sample Types: Tissue Homogenates
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Non-alcoholic fatty liver disease is associated with bacterial translocation and a higher inflammation response in psoriatic patients
Authors: I Belinchón-, P Bellot, D Romero-Pér, I Herraiz-Ro, F Marco, R Frances, JM Ramos-Rinc
Scientific Reports, 2021-04-21;11(1):8593.
Species: Rat
Sample Types: Serum
-
Phgdh serves a protective role in Il?1&beta induced chondrocyte inflammation and oxidative?stress damage
Authors: H Huang, K Liu, H Ou, X Qian, J Wan
Molecular Medicine Reports, 2021-04-13;23(6):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Spirulina platensis and its ingredient biopterin glucoside improved insulin sensitivity in non-alcoholic steatohepatitis model
Authors: Y Fujihara, Y Kodo, SI Miyoshi, R Watanabe, H Toyoda, M Mankura, H Kabuto, F Takayama
Journal of Clinical Biochemistry and Nutrition, 2021-03-25;69(2):151-157.
Species: Rat
Sample Types: Plasma
-
Protective effects of curcumin against rat intestinal inflammation?related motility disorders
Authors: Y Yao, R Luo, S Xiong, C Zhang, Y Zhang
Molecular Medicine Reports, 2021-03-24;23(5):.
Species: Rat
Sample Types: Serum
-
Precisely Fabricated Sulpiride-Loaded Nanolipospheres with Ameliorated Oral Bioavailability and Antidepressant Activity
Authors: SM Mohyeldin, WM Samy, D Ragab, DA Abdelmonsi, RG Aly, NA Elgindy
International Journal of Nanomedicine, 2021-03-09;16(0):2013-2044.
Species: Rat
Sample Types: Tissue Homogenates
-
Vagus nerve stimulation ameliorates L-NAME-induced preeclampsia-like symptoms in rats through inhibition of the inflammatory response
Authors: L Zheng, R Tang, L Shi, M Zhong, Z Zhou
BMC pregnancy and childbirth, 2021-03-04;21(1):177.
Species: Rat
Sample Types: Serum
-
Antioxidative Capacity of Liver- and Adipose-Derived Mesenchymal Stem Cell-Conditioned Media and Their Applicability in Treatment of Type 2 Diabetic Rats
Authors: MM Elshemy, M Asem, KS Allemailem, K Uto, M Ebara, A Nabil
Oxidative Medicine and Cellular Longevity, 2021-02-02;2021(0):8833467.
Species: Rat
Sample Types: Serum
-
Sericin-chitosan-glycosaminoglycans hydrogels incorporated with growth factors for in vitro and in vivo skin repair
Authors: S Sapru, S Das, M Mandal, AK Ghosh, SC Kundu
Carbohydrate polymers, 2021-01-29;258(0):117717.
Species: Rat
Sample Types: Serum
-
Docosahexaenoic fatty acid reduces the pro-inflammatory response induced by IL-1&beta in astrocytes through inhibition of NF-&kappaB and AP-1 transcription factor activation
Authors: E Zgórzy?ska, D Stulczewsk, B Dziedzic, KP Su, A Walczewska
Bmc Neuroscience, 2021-01-27;22(1):4.
Species: Rat
Sample Types: Cell Culture Supernates
-
Cognitive effects of the GSK-3 inhibitor "lithium" in LPS/chronic mild stress rat model of depression: Hippocampal and cortical neuroinflammation and tauopathy
Authors: MA Ebeid, MZ Habib, AM Mohamed, YE Faramawy, SST Saad, OA El-Kharash, HME Magdoub, HA Abd-Alkhal, S Aboul-Foto, AM Abdel-Tawa
Neurotoxicology, 2021-01-06;83(0):77-88.
Species: Rat
Sample Types: Tissue Homogenates
-
Potential of an Interorgan Network Mediated by Toxic Advanced Glycation End-Products in a Rat Model
Authors: S Inoue, T Takata, Y Nakazawa, Y Nakamura, X Guo, S Yamada, Y Ishigaki, M Takeuchi, K Miyazawa
Nutrients, 2020-12-29;13(1):.
Species: Rat
Sample Types: Serum
-
Isoflurane reduces septic neuron injury by HO?1?mediated abatement of inflammation and apoptosis
Authors: L Zhang, X Zhang, T Wu, X Pan, Z Wang
Molecular Medicine Reports, 2020-12-23;23(2):.
Species: Mouse
Sample Types: Serum
-
The antihypertensive agent hydralazine reduced extracellular matrix synthesis and liver fibrosis in nonalcoholic steatohepatitis exacerbated by hypertension
Authors: Y Yuan, H Naito, K Kitamori, S Hashimoto, T Asano, T Nakajima
PLoS ONE, 2020-12-14;15(12):e0243846.
Species: Rat
Sample Types: Serum
-
Angiopoietin-2 is released during anaphylactic hypotension in anesthetized and unanesthetized rats
Authors: T Zhang, T Shibamoto, M Tanida, M Taniguchi, Y Kuda, W Yang, Y Kurata
PLoS ONE, 2020-11-17;15(11):e0242026.
Species: Rat
Sample Types: Plasma
-
Sex Differences in Vagus Nerve Stimulation Effects on Rat Cardiovascular and Immune Systems
Authors: F Yaghouby, K Jang, U Hoang, S Asgari, S Vasudevan
Front Neurosci, 2020-11-06;14(0):560668.
Species: Rat
Sample Types: Plasma
-
SNHG16 aggravates chronic constriction injury-induced neuropathic pain in rats via binding with miR-124-3p and miR-141-3p to upregulate JAG1
Authors: H Li, L Fan, Y Zhang, Y Cao, X Liu
Brain Res Bull, 2020-10-10;165(0):228-237.
Species: Rat
Sample Types: Cell Culture Supernates
-
Anticolitic Effect of Berberine in Rat Experimental Model: Impact of PGE2/p38 MAPK Pathways
Authors: L Jia, K Xue, J Liu, OA Habotta, L Hu, AE Abdel Mone
Mediators Inflamm, 2020-09-29;2020(0):9419085.
Species: Rat
Sample Types: Cell Culture Supernates
-
Selenium Nanoparticles Pre-Treatment Reverse Behavioral, Oxidative Damage, Neuronal Loss and Neurochemical Alterations in Pentylenetetrazole-Induced Epileptic Seizures in Mice
Authors: X Yuan, Z Fu, P Ji, L Guo, AO Al-Ghamdy, A Alkandiri, OA Habotta, AE Abdel Mone, RB Kassab
Int J Nanomedicine, 2020-08-24;15(0):6339-6353.
Species: Mouse
Sample Types: Tissue Homogenates
-
Methane Ameliorates Lipopolysaccharide-Induced Acute Orchitis by Anti-inflammatory, Antioxidative, and Antiapoptotic Effects via Regulation of the PK2/PKR1 Pathway
Authors: C Huang, W Zhang, A Sun, X Zhang, J Guo, R Ji, L Qiao, X Sun, D Zhao
Oxid Med Cell Longev, 2020-08-18;2020(0):7075836.
Species: Rat
Sample Types: Plasma
-
N?acetyl cysteine inhibits the lipopolysaccharide?induced inflammatory response in bone marrow mesenchymal stem cells by suppressing the TXNIP/NLRP3/IL?1&beta signaling pathway
Authors: X Wang, M Jiang, X He, B Zhang, W Peng, L Guo
Molecular Medicine Reports, 2020-08-13;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Inhibitor of RAGE and glucose?induced inflammation in bone marrow mesenchymal stem cells: Effect and mechanism of action
Authors: M Jiang, X Wang, P Wang, W Peng, B Zhang, L Guo
Molecular Medicine Reports, 2020-08-07;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Prevention of Oxygen-Induced Inflammatory Lung Injury by Caffeine in Neonatal Rats
Authors: S Endesfelde, E Strau beta, I Bendix, T Schmitz, C Bührer
Oxid Med Cell Longev, 2020-08-07;2020(0):3840124.
Species: Rat
Sample Types: Tissue Homogenates
-
Effects of dietary fiber on vascular calcification by repetitive diet-induced fluctuations in plasma phosphorus in early-stage chronic kidney disease rats
Authors: M Tani, S Tanaka, K Takamiya, Y Kato, G Harata, F He, M Sakaue, M Ito
Journal of Clinical Biochemistry and Nutrition, 2020-08-06;67(3):283-289.
Species: Rat
Sample Types: Plasma
-
Inhibition of HtrA2 alleviates inflammatory response and cell apoptosis in lipopolysaccharide?induced acute pneumonia in rats
Authors: X Wang
Molecular Medicine Reports, 2020-08-04;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Tetramethylpyrazine alleviates acute kidney injury by inhibiting NLRP3/HIF?1&alpha and apoptosis
Authors: W Sun, A Li, Z Wang, X Sun, M Dong, F Qi, L Wang, Y Zhang, P Du
Molecular Medicine Reports, 2020-07-28;0(0):.
Species: Rat
Sample Types: Serum
-
Histamine 2/3 receptor agonists alleviate perioperative neurocognitive disorders by inhibiting microglia activation through the PI3K/AKT/FoxO1 pathway in aged rats
Authors: YN Chen, HH Sha, YW Wang, Q Zhou, P Bhuiyan, NN Li, YN Qian, HQ Dong
J Neuroinflammation, 2020-07-22;17(1):217.
Species: Rat
Sample Types: Cell Culture Supernates
-
Prophylactic therapy with human amniotic fluid stem cells improved survival in a rat model of lipopolysaccharide-induced neonatal sepsis through immunomodulation via aggregates with peritoneal macrophages
Authors: Y Sato, D Ochiai, Y Abe, H Masuda, M Fukutake, S Ikenoue, Y Kasuga, M Shimoda, Y Kanai, M Tanaka
Stem Cell Res Ther, 2020-07-20;11(1):300.
Species: Rat
Sample Types: Serum
-
Dexmedetomidine alleviates blunt chest trauma and hemorrhagic shock?resuscitation?induced acute lung injury through inhibiting the NLRP3 inflammasome
Authors: T Ming, M Yuan, Q Kong, Q Huang, Z Xia, X Wu
Mol Med Rep, 2020-07-10;22(3):2507-2515.
Species: Rat
Sample Types: Serum
-
HPLC-PDA-MS/MS profiling of secondary metabolites from Opuntia ficus-indica cladode, peel and fruit pulp extracts and their antioxidant, neuroprotective effect in rats with aluminum chloride induced neurotoxicity
Authors: SS El-Hawary, M Sobeh, WK Badr, MAO Abdelfatta, ZY Ali, ME El-Tantawy, MA Rabeh, M Wink
Saudi J Biol Sci, 2020-07-09;27(10):2829-2838.
Species: Rat
Sample Types: Tissue Homogenates
-
Skeletal muscle dysregulation in rheumatoid arthritis: Metabolic and molecular markers in a rodent model and patients
Authors: N Casanova-V, D Constantin, A Filer, RS Hardy, PL Greenhaff, V Chapman
PLoS ONE, 2020-07-07;15(7):e0235702.
Species: Rat
Sample Types: Plasam
-
Xanthan gum protects temporomandibular chondrocytes from IL?1&beta through Pin1/NF?&kappaB signaling pathway
Authors: F Yuan, JL Xie, KY Liu, JL Shan, YG Sun, WG Ying
Mol Med Rep, 2020-06-15;22(2):1129-1136.
Species: Rat
Sample Types: Cell Culture Supernates
-
Comparison of the effect of membrane sizes and fibre arrangements of two membrane oxygenators on the inflammatory response, oxygenation and decarboxylation in a rat model of extracorporeal membrane oxygenation
Authors: F Edinger, E Schneck, C Schulte, J Gehron, S Mueller, M Sander, C Koch
BMC Cardiovasc Disord, 2020-06-15;20(1):294.
Species: Rat
Sample Types: Plasma
-
Activation of FoxO1/SIRT1/RANKL/OPG pathway may underlie the therapeutic effects of resveratrol on aging-dependent male osteoporosis
Authors: O Ameen, RI Yassien, YM Naguib
BMC Musculoskelet Disord, 2020-06-12;21(1):375.
Species: Rat
Sample Types: Serum
-
Long non-coding RNA ANRIL knockdown suppresses apoptosis and pro-inflammatory cytokines while enhancing neurite outgrowth via binding microRNA-125a in a cellular model of Alzheimer's disease
Authors: B Zhou, L Li, X Qiu, J Wu, L Xu, W Shao
Mol Med Rep, 2020-06-02;22(2):1489-1497.
Species: Rat
Sample Types: Cell Culture Supernates
-
Protective effect of Chresta martii extract on the zymosan-induced temporomandibular joint arthritis in rats
Authors: D Rocha do V, MM Bezerra, FI Fernandes, CA Nobre, SC Teixeira, JC Lemos, KM Alves Pere, V de Paulo T, AA Rodrigues, E de Sousa F, M Bernadete, HV Chaves
J Oral Biol Craniofac Res, 2020-05-28;10(3):276-280.
Species: Rat
Sample Types: Cell Lysates
-
Red Beetroot Extract Abrogates Chlorpyrifos-Induced Cortical Damage in Rats
Authors: G Albasher, AS Alsaleh, N Alkubaisi, S Alfarraj, S Alkahtani, M Farhood, N Alotibi, R Almeer
Oxid Med Cell Longev, 2020-03-09;2020(0):2963020.
Species: Rat
Sample Types: Tissue Homogenates
-
Therapeutic Effects of Lithospermate B Complexed with Mg2+ or Zn2+ on Metabolic Syndrome Induced in Rats Fed with High-Fat Diet
Authors: SK Hsieh, NH Lin, YJ Chen, MR Lee, WY Chen, JTC Tzen
Molecules, 2020-02-22;25(4):.
Species: Rat
Sample Types: Whole Blood
-
Effects of repetitive diet-induced fluctuations in plasma phosphorus on vascular calcification and inflammation in rats with early-stage chronic kidney disease
Authors: M Tani, S Tanaka, K Takamiya, M Sakaue, M Ito
J Clin Biochem Nutr, 2020-02-08;66(2):139-145.
Species: Rat
Sample Types: Plasma
-
Comparison of the acute toxicity, analgesic and anti-inflammatory activities and chemical composition changes in Rhizoma anemones Raddeanae caused by vinegar processing
Authors: SS Wang, SY Zhou, XY Xie, L Zhao, Y Fu, GZ Cai, JY Gong
BMC Complement Med Ther, 2020-01-15;20(1):7.
Species: Rat
Sample Types: Serum
-
Identification of microRNA?363?3p as an essential regulator of chondrocyte apoptosis in osteoarthritis by targeting NRF1 through the p53?signaling pathway
Authors: M Zhang, Z Wang, B Li, F Sun, A Chen, M Gong
Mol Med Rep, 2020-01-14;21(3):1077-1088.
Species: Rat
Sample Types: Synovial Fluid
-
Oxidative Stress Parameters in the Liver of Growing Male Rats Receiving Various Alcoholic Beverages
Authors: A Ko?ota, D G??bska, M Oczkowski, J Gromadzka-
Nutrients, 2020-01-06;12(1):.
Species: Rat
Sample Types: Tissue Homogenates
-
Nephroprotective Role of Beta vulgaris L. Root Extract against Chlorpyrifos-Induced Renal Injury in Rats
Authors: G Albasher, R Almeer, S Alarifi, S Alkhtani, M Farhood, FO Al-Otibi, N Alkubaisi, H Rizwana
Evid Based Complement Alternat Med, 2019-11-22;2019(0):3595761.
Species: Rat
Sample Types: Tissue Homogenates
-
Hemorrhagic Shock Sensitized the Diaphragm to Ventilator-Induced Dysfunction through the Activation of IL-6/JAK/STAT Signaling-Mediated Autophagy in Rats
Authors: LJ Zhang, SZ Ni, XL Zhou, Y Zhao
Mediators Inflamm., 2019-11-14;2019(0):3738409.
Species: Rat
Sample Types: Tissue Homogenates
-
Neutrophil activation causes tumor regression in Walker 256 tumor-bearing rats
Authors: WMT Kuwabara, J Andrade-Si, JNB Pereira, JH Scialfa, J Cipolla-Ne
Sci Rep, 2019-11-11;9(1):16524.
Species: Rat
Sample Types: BALF
-
CoQ10 ameliorates monosodium glutamate-induced alteration in detrusor activity and responsiveness in rats via anti-inflammatory, anti-oxidant and channel inhibiting mechanisms
Authors: DF El Agamy, YM Naguib
BMC Urol, 2019-10-28;19(1):103.
Species: Rat
Sample Types: Serum
-
Interactive effects of maternal and weaning high linoleic acid intake on hepatic lipid metabolism, oxylipins profile and hepatic steatosis in offspring
Authors: J Marchix, D Catheline, C Duby, N Monthéan-B, F Boissel, F Pédrono, G Boudry, P Legrand
J. Nutr. Biochem., 2019-10-26;75(0):108241.
Species: Rat
Sample Types: Plasma
-
IL?1beta increases the expression of inflammatory factors in synovial fluid?derived fibroblast?like synoviocytes via activation of the NF?kappaB?mediated ERK?STAT1 signaling pathway
Authors: J Yang, J Wang, X Liang, H Zhao, J Lu, Q Ma, B Jing, F Tian
Mol Med Rep, 2019-10-21;0(0):.
Species: Rat
Sample Types: Whole Blood
-
Low-Energy Extracorporeal Shock Wave Ameliorates Streptozotocin Induced Diabetes and Promotes Pancreatic Beta Cells Regeneration in a Rat Model
Authors: CC Hsiao, CC Lin, YS Hou, JY Ko, CJ Wang
Int J Mol Sci, 2019-10-05;20(19):.
Species: Rat
Sample Types: Tissue Lysates
-
Human mesenchymal stromal cells ameliorate complement induced inflammatory cascade and improve renal functions in a rat model of ischemia-reperfusion induced acute kidney injury
Authors: S Zilberman-, R Abu-Hamad, R Zarura, M Sova, Y Hachmo, M Stark, S Neuman, S Slavin, S Efrati
PLoS ONE, 2019-09-12;14(9):e0222354.
Species: Rat
Sample Types: Serum
-
Ameliorative Effect of Beta vulgaris Root Extract on Chlorpyrifos-Induced Oxidative Stress, Inflammation and Liver Injury in Rats
Authors: G Albasher, R Almeer, FO Al-Otibi, N Al-Kubaisi, AM Mahmoud
Biomolecules, 2019-07-07;9(7):.
Species: Rat
Sample Types: Tissue Homogenates
-
Rice Porridge Containing Welsh Onion Root Water Extract Alleviates Osteoarthritis-Related Pain Behaviors, Glucose Levels, and Bone Metabolism in Osteoarthritis-Induced Ovariectomized Rats
Authors: HJ Yang, MJ Kim, JY Qiu, T Zhang, X Wu, DJ Jang, S Park
Nutrients, 2019-06-30;11(7):.
Species: Rat
Sample Types: Serum
-
Sex-specific maternofetal innate immune responses triggered by group B Streptococci
Authors: MJ Allard, A Giraud, M Segura, G Sebire
Sci Rep, 2019-06-13;9(1):8587.
Species: Rat
Sample Types: Protein
-
Atractylenolide III Attenuates Muscle Wasting in Chronic Kidney Disease via the Oxidative Stress-Mediated PI3K/AKT/mTOR Pathway
Authors: M Wang, R Hu, Y Wang, L Liu, H You, J Zhang, X Wu, T Pei, F Wang, L Lu, W Xiao, L Wei
Oxid Med Cell Longev, 2019-04-18;2019(0):1875471.
Species: Rat
Sample Types: Serum
-
Exosomes derived from mangiferin?stimulated perivascular adipose tissue ameliorate endothelial dysfunction
Authors: Q Zhao, J Yang, B Liu, F Huang, Y Li
Mol Med Rep, 2019-04-04;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Neuroinflammation induced by the peptide amyloid-? (25-35) increase the presence of galectin-3 in astrocytes and microglia and impairs spatial memory
Authors: E Ramírez, C Sánchez-Ma, MA Mayoral, L Mendieta, V Alatriste, A Patricio-M, ID Limón
Neuropeptides, 2019-02-14;0(0):.
Species: Rat
Sample Types: Tissue Homogenates
-
Elevated pulmonary arterial pressure in Zucker diabetic fatty rats
Authors: D Morales-Ca, M Callejo, B Barreira, G Mondejar-P, S Esquivel-R, S Ramos, MÁ Martín, A Cogolludo, L Moreno, F Perez-Vizc
PLoS ONE, 2019-01-28;14(1):e0211281.
Species: Rat
Sample Types: Serum
-
Hepatokine ?1-Microglobulin Signaling Exacerbates Inflammation and Disturbs Fibrotic Repair in Mouse Myocardial Infarction
Authors: D Hakuno, M Kimura, S Ito, J Satoh, Y Nakashima, T Horie, Y Kuwabara, M Nishiga, Y Ide, O Baba, H Nishi, T Nakao, T Nishino, F Nakazeki, S Koyama, R Hanada, RR Randolph, J Endo, T Kimura, K Ono
Sci Rep, 2018-11-13;8(1):16749.
Species: Rat
Sample Types: Cell Culture Supernates
-
Valproate reduces neuroinflammation and neuronal death in a rat chronic constriction injury model
Authors: JY Chen, LW Chu, KI Cheng, SL Hsieh, YS Juan, BN Wu
Sci Rep, 2018-11-07;8(1):16457.
Species: Rat
Sample Types: Tissue Homogenates
-
Trans-repression of NF?B pathway mediated by PPAR? improves vascular endothelium insulin resistance
Authors: Y Kong, Y Gao, D Lan, Y Zhang, R Zhan, M Liu, Z Zhu, G Zeng, Q Huang
J. Cell. Mol. Med., 2018-11-05;0(0):.
Species: Rat
Sample Types: Serum
-
MiR-10 targets NgR to modulate the proliferation of microglial cells and the secretion of inflammatory cytokines
Authors: W Wang, R Zhan, J Zhou, J Wang, S Chen
Exp. Mol. Pathol., 2018-10-09;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Complement depletion with cobra venom factor alleviates acute hepatic injury induced by ischemia?reperfusion
Authors: B Wang, H Xu, J Li, HM Gao, YH Xing, Z Lin, HJ Li, YQ Wang, SH Cao
Mol Med Rep, 2018-09-14;0(0):.
Species: Rat
Sample Types: Serum
-
Lipoic Acid Prevents High-Fat Diet-Induced Hepatic Steatosis in Goto Kakizaki Rats by Reducing Oxidative Stress Through Nrf2 Activation
Authors: CM Sena, MA Cipriano, MF Botelho, RM Seiça
Int J Mol Sci, 2018-09-11;19(9):.
Species: Rat
Sample Types: Tissue Homogenates
-
Effect of Xuefu Zhuyu Decoction Pretreatment on Myocardium in Sepsis Rats
Authors: F Meng, H Lai, Z Luo, Y Liu, X Huang, J Chen, B Liu, Y Guo, Y Cai, Q Huang
Evid Based Complement Alternat Med, 2018-09-09;2018(0):2939307.
Species: Rat
Sample Types: Serum
-
Dysregulation of PI3K-Akt-mTOR pathway in brain of streptozotocin-induced type 2 diabetes mellitus in Wistar rats
Authors: S Bathina, UN Das
Lipids Health Dis, 2018-07-24;17(1):168.
Species: Rat
Sample Types: Plasma
-
Cobra Venom Factor-induced complement depletion protects against lung ischemia reperfusion injury through alleviating blood-air barrier damage
Authors: C Haihua, W Wei, H Kun, L Yuanli, L Fei
Sci Rep, 2018-07-09;8(1):10346.
Species: Rat
Sample Types: BALF
-
Anti-inflammatory effect of Mongolian drug Naru-3 on traumatic spinal cord injury and its mechanism of action
Authors: B Baiyila, B He, G He, T Long
J. Int. Med. Res., 2018-04-03;0(0):3000605187601.
Species: Rat
Sample Types: Serum
-
Role of dysfunctional adipocytes in cholesterol-induced nonobese metabolic syndrome
Authors: JP Huang, SC Hsu, YJ Meir, PS Hsieh, CC Chang, KH Chen, JK Chen, LM Hung
J. Mol. Endocrinol., 2018-03-26;0(0):.
Species: Rat
Sample Types: Plasma
-
The local cytokine and growth factor response to rhBMP-2 after spinal fusion
Authors: JD Koerner, DZ Markova, GD Schroeder, BP Calio, A Shah, CW Brooks, AR Vaccaro, DG Anderson, CK Kepler
Spine J, 2018-03-14;0(0):.
Species: Rat
Sample Types: Tissue Lysates
Applications: ELISA (Standard) -
In Vitro and In Vivo Short-Term Pulmonary Toxicity of Differently Sized Colloidal Amorphous SiO?
Authors: M Wiemann, UG Sauer, A Vennemann, S Bäcker, JG Keller, L Ma-Hock, W Wohlleben, R Landsiedel
Nanomaterials (Basel), 2018-03-13;8(3):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Toll-like receptor 3 activation impairs excitability and synaptic activity via TRIF signalling in immature rat and human neurons
Authors: L Ritchie, R Tate, LH Chamberlai, G Robertson, M Zagnoni, T Sposito, S Wray, JA Wright, CE Bryant, NJ Gay, TJ Bushell
Neuropharmacology, 2018-03-02;135(0):1-10.
Species: Rat
Sample Types: Cell Culture Supernates
-
Interleukin-10 attenuates impairment of the blood-brain barrier in a severe acute pancreatitis rat model
Authors: R Lin, F Chen, S Wen, T Teng, Y Pan, H Huang
J Inflamm (Lond), 2018-02-27;15(0):4.
Species: Rat
Sample Types: Serum
Applications: ELISA (detection) -
The PI3K/Akt/FOXO3a pathway regulates regeneration following spinal cord injury in adult rats through TNF-? and p27kip1 expression
Authors: H Lu, LH Zhang, L Yang, PF Tang
Int. J. Mol. Med., 2018-02-06;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Ablation of the Right Cardiac Vagus Nerve Reduces Acetylcholine Content without Changing the Inflammatory Response during Endotoxemia
Authors: K Plaschke, TQM Do, F Uhle, T Brenner, MA Weigand, J Kopitz
Int J Mol Sci, 2018-02-01;19(2):.
Species: Rat
Sample Types: Plasma
-
Short-term inhalation study of graphene oxide nanoplates
Authors: YH Kim, MS Jo, JK Kim, JH Shin, JE Baek, HS Park, HJ An, JS Lee, BW Kim, HP Kim, KH Ahn, K Jeon, SM Oh, JH Lee, T Workman, EM Faustman, IJ Yu
Nanotoxicology, 2018-02-01;0(0):1-15.
Species: Rat
Sample Types: Cell Culture Supernates
-
?-Melanocyte-Stimulating Hormone Protects Early Diabetic Retina from Blood-Retinal Barrier Breakdown and Vascular Leakage via MC4R
Authors: S Cai, Q Yang, M Hou, Q Han, H Zhang, J Wang, C Qi, Q Bo, Y Ru, W Yang, Z Gu, R Wei, Y Cao, X Li, Y Zhang
Cell. Physiol. Biochem., 2018-01-25;45(2):505-522.
Species: Rat
Sample Types: Tissue Homogenates
-
Green tea extract attenuates LPS-induced retinal inflammation in rats
Authors: JL Ren, QX Yu, WC Liang, PY Leung, TK Ng, WK Chu, CP Pang, SO Chan
Sci Rep, 2018-01-11;8(1):429.
Species: Rat
Sample Types: Vitreous Humor
-
Amelioration of streptozotocin-induced type 2 diabetes mellitus in Wistar rats by arachidonic acid
Authors: NKV Gundala, VGM Naidu, UN Das
Biochem. Biophys. Res. Commun., 2018-01-06;0(0):.
Species: Rat
Sample Types: Plasma
-
A Novel Role of SIRT1/ FGF-21 in Taurine Protection Against Cafeteria Diet-Induced Steatohepatitis in Rats
Authors: AH Abd Elwaha, BK Ramadan, MF Schaalan, AM Tolba
Cell. Physiol. Biochem., 2017-09-22;43(2):644-659.
Species: Rat
Sample Types: Tissue Homogenates
-
Scavenging of reactive oxygen species by astaxanthin inhibits epithelial-mesenchymal transition in high glucose-stimulated mesothelial cells
Authors: K Hara, C Hamada, K Wakabayash, R Kanda, K Kaneko, S Horikoshi, Y Tomino, Y Suzuki
PLoS ONE, 2017-09-19;12(9):e0184332.
Species: Rat
Sample Types: Cell Culture Supernates
-
Protective effects of GV1001 on myocardial ischemia?reperfusion injury
Authors: JE Chang, HJ Kim, S Jheon, C Lim
Mol Med Rep, 2017-09-19;0(0):.
Species: Rat
Sample Types: Tissue Homogenates
-
Betaine attenuates chronic alcohol?induced fatty liver by broadly regulating hepatic lipid metabolism
Authors: W Yang, L Huang, J Gao, S Wen, Y Tai, M Chen, Z Huang, R Liu, C Tang, J Li
Mol Med Rep, 2017-08-21;16(4):5225-5234.
Species: Rat
Sample Types: Tissue Homogenates
-
Effects of TNF-? on penile structure alteration in rats with hyperprolactinemia
Authors: ZL Wang, LY Yang, HH Chen, HH Lin, YT Tsai, WJ Huang
PLoS ONE, 2017-08-01;12(8):e0181952.
Species: Rat
Sample Types: Serum
-
Oral Administration of Red Ginseng Extract Promotes Neurorestoration after Compressive Spinal Cord Injury in Rats
Authors: P Zhu, K Samukawa, H Fujita, H Kato, M Sakanaka
Evid Based Complement Alternat Med, 2017-07-30;2017(0):1265464.
Species: Rat
Sample Types: Tissue Homogenates
-
Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate?induced osteoarthritis rats
Authors: JW Jeong, HH Lee, J Kim, EO Choi, H Hwang-Bo, HJ Kim, MY Kim, KI Ahn, GY Kim, KW Lee, KY Kim, SG Kim, SH Hong, C Park, HJ Cha, YH Choi
Mol Med Rep, 2017-07-21;0(0):.
Species: Rat
Sample Types: Serum
-
Podophyllotoxin Extracted from Juniperus sabina Fruit Inhibits Rat Sperm Maturation and Fertility by Promoting Epididymal Epithelial Cell Apoptosis
Authors: S Xie, G Li, L Qu, R Zhong, P Chen, Z Lu, J Zhou, X Guo, Z Li, A Ma, Y Qian, Y Zhu
Evid Based Complement Alternat Med, 2017-07-04;2017(0):6958982.
Species: Rat
Sample Types: Cell Culture Supernates
-
Estrogen-dependent efficacy of limb ischemic preconditioning in female rats
Authors: L Pócs, Á Janovszky, D Garab, G Terhes, I Ocsovszki, J Kaszaki, M Boros, J Piffkó, A Szabó
J. Orthop. Res., 2017-06-28;0(0):.
Species: Rat
Sample Types: Plasma
-
Resveratrol protects against ICV collagenase-induced neurobehavioral and biochemical deficits
Authors: N Singh, Y Bansal, R Bhandari, L Marwaha, R Singh, K Chopra, A Kuhad
J Inflamm (Lond), 2017-06-09;14(0):14.
Species: Rat
Sample Types: Tissue Homogenates
-
Pharmacologic targeting ERK1/2 attenuates the development and progression of hyperuricemic nephropathy in rats
Authors: N Liu, L Xu, Y Shi, L Fang, H Gu, H Wang, X Ding, S Zhuang
Oncotarget, 2017-05-16;8(20):33807-33826.
Species: Rat
Sample Types: Tissue Culture Supernates
-
Activated Microglia Desialylate and Phagocytose Cells via Neuraminidase, Galectin-3, and Mer Tyrosine Kinase
Authors: K Nomura, A Vilalta, DH Allendorf, TC Hornik, GC Brown
J. Immunol., 2017-05-12;0(0):.
Species: Rat
Sample Types: Cell Culture Supernates
-
Sodium tanshinone IIA sulfonate improves inflammation, aortic endothelial cell apoptosis, disseminated intravascular coagulation and multiple organ damage in a rat heat stroke model
Authors: F Chen, H Li, G Zhu, X Chen, Z Tang
Mol Med Rep, 2017-05-11;0(0):.
Species: Rat
Sample Types: Serum
-
The Effects of Remifentanil on Expression of High Mobility Group Box 1 in Septic Rats
Authors: KH Seo, JW Choi, HS Jung, H Yoo, JD Joo
J. Korean Med. Sci, 2017-03-01;32(3):542-551.
Species: Rat
Sample Types: Serum
-
Investigation of the effect of phlomisoside F on complete Freund's adjuvant-induced arthritis
Authors: X Zhang, Y Dong, H Dong, W Zhang, F Li
Exp Ther Med, 2016-12-22;13(2):710-716.
Species: Rat
Sample Types: Serum
-
Postconditioning: Toll-erating mesenteric ischemia-reperfusion injury?
Authors: Attila Szijártó
Surgery, 2016-11-11;0(0):.
Species: Rat
Sample Types: Serum
-
Transport patterns of anti-TNF-? in burn wounds: Therapeutic implications of hyaluronic acid conjugation
Authors: Newell R Washburn
Biomaterials, 2016-11-04;114(0):10-22.
Species: Rat
Sample Types: Complex Sample Type
-
The analgesic effect of rolipram is associated with the inhibition of the activation of the spinal astrocytic JNK/CCL2 pathway in bone cancer pain
Authors: Chi-Hua Guo
Int. J. Mol. Med, 2016-09-30;38(5):1433-1442.
Species: Rat
Sample Types: Tissue Homogenates
-
Chronic Cognitive Dysfunction after Traumatic Brain Injury Is Improved with a Phosphodiesterase 4B Inhibitor
J Neurosci, 2016-07-06;36(27):7095-108.
Species: Rat
Sample Types: Tissue Homogenates
-
Co-Administration of Cholesterol-Lowering Probiotics and Anthraquinone from Cassia obtusifolia L. Ameliorate Non-Alcoholic Fatty Liver.
Authors: Mei L, Tang Y, Li M, Yang P, Liu Z, Yuan J, Zheng P
PLoS ONE, 2015-09-16;10(9):e0138078.
Species: Rat
Sample Types: Serum
-
IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation.
Authors: Sun J, Zhang S, Zhang X, Zhang X, Dong H, Qian Y
J Neuroinflammation, 2015-09-15;12(0):165.
Species: Rat
Sample Types: Serum
-
The extent of irradiation-induced long-term visceral organ damage depends on cranial/brain exposure.
Authors: Boittin F, Denis J, Mayol J, Martigne P, Raffin F, Coulon D, Grenier N, Drouet M, Herodin F
PLoS ONE, 2015-04-02;10(4):e0122900.
Species: Rat
Sample Types: Plasma
-
Non-invasive technology that improves cardiac function after experimental myocardial infarction: Whole Body Periodic Acceleration (pGz).
Authors: Uryash A, Bassuk J, Kurlansky P, Altamirano F, Lopez J, Adams J
PLoS ONE, 2015-03-25;10(3):e0121069.
Species: Rat
Sample Types: Tissue Homogenates
-
Inhibition of the spinal astrocytic JNK/MCP-1 pathway activation correlates with the analgesic effects of tanshinone IIA sulfonate in neuropathic pain.
Authors: Tang J, Zhu C, Li Z, Liu X, Sun S, Zhang T, Luo Z, Zhang H, Li W
J Neuroinflammation, 2015-03-25;12(0):57.
Species: Rat
Sample Types: Tissue Homogenates
-
Xanthine oxidase inhibition alleviates the cardiac complications of insulin resistance: effect on low grade inflammation and the angiotensin system.
Authors: El-Bassossy H, Watson M
J Transl Med, 2015-03-06;13(0):82.
Species: Rat
Sample Types: Serum
-
Ameliorative effect of allopurinol on vascular complications of insulin resistance.
Authors: El-Bassossy H, Elberry A, Azhar A, Ghareib S, Alahdal A
J Diabetes Res, 2015-02-15;2015(0):178540.
Species: Rat
Sample Types: Serum
-
Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer.
Authors: Chuffa L, Fioruci-Fontanelli B, Mendes L, Ferreira Seiva F, Martinez M, Favaro W, Domeniconi R, Pinheiro P, Delazari Dos Santos L, Martinez F
BMC Cancer, 2015-02-06;15(0):34.
Species: Rat
Sample Types: Tissue Culture Supernates
-
Preventive effects of probiotic bacteria Lactobacillus plantarum and dietary fiber in chemically-induced mammary carcinogenesis.
Authors: Kassayova M, Bobrov N, Strojny L, Kiskova T, Mikes J, Demeckova V, Orendas P, Bojkova B, Pec M, Kubatka P, Bomba A
Anticancer Res, 2014-09-01;34(9):4969-75.
Species: Rat
Sample Types: Serum
-
Prolonged neuroinflammation after lipopolysaccharide exposure in aged rats.
Authors: Fu H, Yang T, Xiao W, Fan L, Wu Y, Terrando N, Wang T
PLoS ONE, 2014-08-29;9(8):e106331.
Species: Rat
Sample Types: Serum
-
Improving membrane based multiplex immunoassays for semi-quantitative detection of multiple cytokines in a single sample.
Authors: Altara, Raffaele, Manca, Marco, Hessel, Marleen, Janssen, Ben J, Struijker-Boudier, Harry H, Hermans, Rob J J, Blankesteijn, W Matthi
BMC Biotechnol, 2014-07-15;14(0):63.
Species: Rat
Sample Types: Serum
-
Melatonin synergized with cyclosporine A improves cardiac allograft survival by suppressing inflammation and apoptosis.
Authors: Liu C, Hong T, Shao M, Chen Z, Wang C
Mol Med Rep, 2014-07-15;10(3):1323-8.
Species: Rat
Sample Types: Serum
-
Catalpol ameliorates sodium taurocholate-induced acute pancreatitis in rats via inhibiting activation of nuclear factor kappa B.
Authors: Xiao W, Yin G, Fan Y, Qiu L, Cang X, Yu G, Hu Y, Xing M, Wu D, Wang X, Hu G, Wan R
Int J Mol Sci, 2014-07-04;15(7):11957-72.
Species: Rat
Sample Types: Serum
-
Dose responsive effects of subcutaneous pentosan polysulfate injection in mucopolysaccharidosis type VI rats and comparison to oral treatment.
Authors: Frohbergh M, Ge Y, Meng F, Karabul N, Solyom A, Lai A, Iatridis J, Schuchman E, Simonaro C
PLoS ONE, 2014-06-25;9(6):e100882.
Species: Rat
Sample Types: Serum
-
Pentoxifylline alleviates cardiac ischemia and dysfunction following experimental angina in insulin resistance.
Authors: Azhar A, El-Bassossy H
PLoS ONE, 2014-05-29;9(5):e98281.
Species: Rat
Sample Types: Serum
-
Epidermal growth factor receptor inhibitor ameliorates excessive astrogliosis and improves the regeneration microenvironment and functional recovery in adult rats following spinal cord injury.
Authors: Li Z, Li J, Wang L, Zhang J, Wu J, Mao X, Shi G, Wang Q, Wang F, Zou J
J Neuroinflammation, 2014-04-05;11(0):71.
Species: Rat
Sample Types: Cell Culture Supernates
-
Deoxyglucose prevents neurodegeneration in culture by eliminating microglia.
Authors: Vilalta, Anna, Brown, Guy C
J Neuroinflammation, 2014-03-26;11(0):58.
Species: Rat
Sample Types: Cell Culture Supernates
-
Rhamnogalacturonan from Acmella oleracea (L.) R.K. Jansen: gastroprotective and ulcer healing properties in rats.
Authors: Maria-Ferreira D, da Silva L, Mendes D, Cabrini D, Nascimento A, Iacomini M, Cipriani T, Santos A, Werner M, Baggio C
PLoS ONE, 2014-01-08;9(1):e84762.
Species: Rat
Sample Types: Tissue Culture Supernates
-
Cerebral ischemia is exacerbated by extracellular nicotinamide phosphoribosyltransferase via a non-enzymatic mechanism.
Authors: Zhao B, Zhang M, Han X, Zhang X, Xing Q, Dong X, Shi Q, Huang P, Lu Y, Wei E, Xia Q, Zhang W, Tang C
PLoS ONE, 2013-12-31;8(12):e85403.
Species: Rat
Sample Types: Cell Culture Supernates
-
Ubiquitin-specific peptidase 5, a target molecule of vialinin A, is a key molecule of TNF-alpha production in RBL-2H3 cells.
Authors: Yoshioka Y, Ye Y, Okada K, Taniguchi K, Yoshida A, Sugaya K, Onose J, Koshino H, Takahashi S, Yajima A, Yajima S, Abe N
PLoS ONE, 2013-12-04;8(12):e80931.
Species: Rat
Sample Types: Whole Cells
-
Mechanical ventilation enhances HMGB1 expression in an LPS-induced lung injury model.
Authors: Ding N, Wang F, Xiao H, Xu L, She S
PLoS ONE, 2013-09-10;8(9):e74633.
Species: Rat
Sample Types: BALF
-
Suppression of neuroinflammatory and apoptotic signaling cascade by curcumin alone and in combination with piperine in rat model of olfactory bulbectomy induced depression.
Authors: Rinwa P, Kumar A, Garg S
PLoS ONE, 2013-04-17;8(4):e61052.
Species: Rat
Sample Types: Tissue Homogenates
-
Medium-chain fatty acid-sensing receptor, GPR84, is a proinflammatory receptor.
Authors: Suzuki M, Takaishi S, Nagasaki M, Onozawa Y, Iino I, Maeda H, Komai T, Oda T
J Biol Chem, 2013-02-28;288(15):10684-91.
Species: Rat
Sample Types: Serum
-
Caspase inhibitors protect neurons by enabling selective necroptosis of inflamed microglia.
Authors: Fricker M, Vilalta A, Tolkovsky A, Brown G
J Biol Chem, 2013-02-05;288(13):9145-52.
Species: Rat
Sample Types: Cell Culture Supernates
-
Positional isomers of aspirin are equally potent in inhibiting colon cancer cell growth: differences in mode of cyclooxygenase inhibition.
Authors: Kodela R, Chattopadhyay M, Goswami S, Gan Z, Rao P, Nia K, Velazquez-Martinez C, Kashfi K
J Pharmacol Exp Ther, 2013-01-24;345(1):85-94.
Species: Rat
Sample Types: Plasma
-
A short course of infusion of a hydrogen sulfide-donor attenuates endotoxemia induced organ injury via stimulation of anti-inflammatory pathways, with no additional protection from prolonged infusion.
Cytokine, 2012-12-23;61(2):614-21.
Species: Rat
Sample Types: BALF
-
Keratinocyte expression of inflammatory mediators plays a crucial role in substance P-induced acute and chronic pain.
J Neuroinflammation, 2012-07-23;9(0):181.
Species: Rat
Sample Types: Tissue Homogenates
-
Glial tumor necrosis factor alpha (TNF-alpha) generates metaplastic inhibition of spinal learning.
Authors: Huie JR, Baumbauer KM, Lee KH, Bresnahan JC, Beattie MS, Ferguson AR, Grau JW
PLoS ONE, 2012-06-20;7(6):e39751.
Species: Rat
Sample Types: Tissue Homogenates
-
The effects of low-dose ionizing radiation in the activated rat basophilic leukemia (RBL-2H3) mast cells.
Authors: Joo H, Nam S, Yang K, Kim C, Jin Y, Kim J
J Biol Chem, 2012-06-14;287(33):27789-95.
Species: Rat
Sample Types: Cell Culture Supernates
-
Anti-inflammatory effects of FTY720 do not prevent neuronal cell loss in a rat model of optic neuritis.
Authors: Rau CR, Hein K, Sattler MB, Kretzschmar B, Hillgruber C, McRae BL, Diem R, Bahr M
Am. J. Pathol., 2011-02-26;178(4):1770-81.
Species: Rat
Sample Types: Tissue Homogenates
-
Systemic effects of ulna loading in male rats during functional adaptation.
Authors: Sample SJ, Collins RJ, Wilson AP, Racette MA, Behan M, Markel MD, Kalscheur VL, Hao Z, Muir P
J. Bone Miner. Res., 2010-09-01;25(9):2016-28.
Species: Rat
Sample Types: Plasma
-
Vipera aspis venom reduces lethality and down-regulates tumor necrosis factor-alpha in a rat model of LPS-induced sepsis.
Authors: Frolkis I, Klein Y, Locker C, Adi N, Dahan E, Uretzsky G, Shapira I, Sorkine P
Cytokine, 2010-01-19;49(3):319-24.
Species: Rat
Sample Types: Serum
-
Protease-activated receptor 2 blocking peptide counteracts endotoxin-induced inflammation and coagulation and ameliorates renal fibrin deposition in a rat model of acute renal failure.
Authors: Jesmin S, Gando S, Zaedi S, Prodhan SH, Sawamura A, Miyauchi T, Hiroe M, Yamaguchi N
Shock, 2009-12-01;32(6):626-32.
Species: Rat
Sample Types: Plasma
-
Tumor necrosis factor-alpha participates in apoptosis in the limbic system after myocardial infarction.
Authors: Kaloustian S, Bah TM, Rondeau I, Mathieu S, Lada-Moldovan L, Ryvlin P, Godbout R, Rousseau G
Apoptosis, 2009-11-01;0(0):.
Species: Rat
Sample Types: Plasma
-
House dust mite induces direct airway inflammation in vivo: implications for future disease therapy?
Authors: De Alba J, Raemdonck K, Dekkak A, Collins M, Wong S, Nials AT, Knowles RG, Belvisi MG, Birrell MA
Eur. Respir. J., 2009-10-19;35(6):1377-87.
Species: Rat
Sample Types: BALF
-
Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis.
Authors: Costello J, Higgins B, Contreras M, Chonghaile MN, Hassett P, O'Toole D, Laffey JG
Crit. Care Med., 2009-08-01;37(8):2412-20.
Species: Rat
Sample Types: BALF
-
Effects of an antagonist of the gastrin-releasing peptide receptor in an animal model of uveitis.
Authors: Pereira DV, Steckert AV, Mina F, Petronilho F, Roesler R, Schwartsmann G, Ritter C, Dal-Pizzol F
Invest. Ophthalmol. Vis. Sci., 2009-06-10;50(11):5300-3.
Species: Rat
Sample Types: Aqueous Humor
-
In vivo Angiotensin II AT1 receptor blockade selectively inhibits LPS-induced innate immune response and ACTH release in rat pituitary gland.
Authors: Sanchez-Lemus E, Benicky J, Pavel J, Saavedra JM
Brain Behav. Immun., 2009-05-07;23(7):945-57.
Species: Rat
Sample Types: Plasma
-
Role of sensory innervation in the rat pulmonary neutrophil recruitment induced by staphylococcal enterotoxins type A and B.
Authors: Desouza IA, Camargo EA, Mariano NS, Optiz-Neto JB, Resende JS, Mello GC, Costa SK, De Nucci G, Antunes E
Eur. J. Pharmacol., 2009-04-16;613(1):128-34.
Species: Rat
Sample Types: Cell Culture Supernates
-
Mechanism of hepatoprotection in proestrus female rats following trauma-hemorrhage: heme oxygenase-1-derived normalization of hepatic inflammatory responses.
Authors: Yang S, Hu S, Chen J, Choudhry MA, Rue LW, Bland KI, Chaudry IH
J. Leukoc. Biol., 2009-02-24;85(6):1015-26.
Species: Rat
Sample Types: Serum
-
4-thiouridine induces dose-dependent reduction of oedema, leucocyte influx and tumour necrosis factor in lung inflammation.
Authors: Evaldsson C, Ryden I, Rosen A, Uppugunduri S
Clin. Exp. Immunol., 2008-12-01;155(2):330-8.
Species: Rat
Sample Types: BALF
-
Effects of the immunomodulator, VGX-1027, in endotoxin-induced uveitis in Lewis rats.
Authors: Mangano K, Sardesai NY, Quattrocchi C, Mazzon E, Cuzzocrea S, Bendtzen K, Meroni PL, Kim JJ, Nicoletti F
Br. J. Pharmacol., 2008-09-08;155(5):722-30.
Species: Rat
Sample Types: Aqueous Humor
-
Role of central beta-adrenergic receptors in regulating proinflammatory cytokine responses to a peripheral bacterial challenge.
Authors: Johnson JD, Cortez V, Kennedy SL, Foley TE, Hanson H, Fleshner M
Brain Behav. Immun., 2008-05-12;22(7):1078-86.
Species: Rat
Sample Types: Plasma
-
Substance P acts via the neurokinin receptor 1 to elicit bronchoconstriction, oxidative stress, and upregulated ICAM-1 expression after oil smoke exposure.
Authors: Li PC, Chen WC, Chang LC, Lin SC
Am. J. Physiol. Lung Cell Mol. Physiol., 2008-03-07;294(5):L912-20.
Species: Rat
Sample Types: BALF
-
Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats.
Authors: Choi G, Hofstra JJ, Roelofs JJ, Rijneveld AW, Bresser P, van der Zee JS, Florquin S, van der Poll T, Levi M, Schultz MJ
Crit. Care Med., 2008-01-01;36(1):204-10.
Species: Rat
Sample Types: BALF
-
Role of sex steroids in modulating tumor necrosis factor alpha-induced changes in vascular function and blood pressure.
Authors: LaMarca BD, Chandler DL, Grubbs L, Bain J, McLemore GR, Granger JP, Ryan MJ
Am. J. Hypertens., 2007-11-01;20(11):1216-21.
Species: Rat
Sample Types: Serum
-
Triamcinolone acetonide protects the rat retina from STZ-induced acute inflammation and early vascular leakage.
Authors: Kim YH, Choi MY, Kim YS, Park CH, Lee JH, Chung IY, Yoo JM, Choi WS, Cho GJ, Kang SS
Life Sci., 2007-08-31;81(14):1167-73.
Species: Rat
Sample Types: Tissue Homogenates
-
Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation.
Authors: Stevenson CS, Docx C, Webster R, Battram C, Hynx D, Giddings J, Cooper PR, Chakravarty P, Rahman I, Marwick JA, Kirkham PA, Charman C, Richardson DL, Nirmala NR, Whittaker P, Butler K
Am. J. Physiol. Lung Cell Mol. Physiol., 2007-08-24;293(5):L1183-93.
Species: Rat
Sample Types: BALF
-
In the adult mesenchymal stem cell population, source gender is a biologically relevant aspect of protective power.
Authors: Crisostomo PR, Markel TA, Wang M, Lahm T, Lillemoe KD, Meldrum DR
Surgery, 2007-08-01;142(2):215-21.
Species: Rat
Sample Types: Cell Culture Supernates
-
Expression of the mu opioid receptor in the human immunodeficiency virus type 1 transgenic rat model.
Authors: Chang SL, Beltran JA, Swarup S
J. Virol., 2007-06-06;81(16):8406-11.
Species: Rat
Sample Types: Serum
-
Natural anticoagulants limit lipopolysaccharide-induced pulmonary coagulation but not inflammation.
Authors: Choi G, Vlaar AP, Schouten M, Van't Veer C, van der Poll T, Levi M, Schultz MJ
Eur. Respir. J., 2007-05-30;30(3):423-8.
Species: Rat
Sample Types: Tissue Homogenates
-
5-aminosalicylic acid improves indomethacin-induced enteropathy by inhibiting iNOS transcription in rats.
Authors: Nandi J, Saud B, Zinkievich JM, Palma DT, Levine RA
Dig. Dis. Sci., 2007-05-15;53(1):123-32.
Species: Rat
Sample Types: Serum
-
Changes of gene expression of iron regulatory proteins during turpentine oil-induced acute-phase response in the rat.
Authors: Sheikh N, Dudas J, Ramadori G
Lab. Invest., 2007-04-09;87(7):713-25.
Species: Rat
Sample Types: Serum
-
Prothymosin alpha lacking the nuclear localization signal as an effective gene therapeutic strategy in collagen-induced arthritis.
Authors: Shiau AL, Chen SY, Chang MY
J. Immunol., 2007-04-01;178(7):4688-94.
Species: Rat
Sample Types: Tissue Homogenates
-
Cell-based angiopoietin-1 gene therapy for acute lung injury.
Authors: McCarter SD, Mei SH, Lai PF, Zhang QW, Parker CH, Suen RS, Hood RD, Zhao YD, Deng Y, Han RN, Dumont DJ, Stewart DJ
Am. J. Respir. Crit. Care Med., 2007-02-22;175(10):1014-26.
Species: Rat
Sample Types: BALF
-
The arthritis severity quantitative trait loci Cia4 and Cia6 regulate neutrophil migration into inflammatory sites and levels of TNF-alpha and nitric oxide.
Authors: Laragione T, Yarlett NC, Brenner M, Mello A, Sherry B, Miller EJ, Metz CN, Gulko PS
J. Immunol., 2007-02-15;178(4):2344-51.
Species: Rat
Sample Types: Air Pouch Exudate
-
Interleukin-6 mediates low-threshold mechanical allodynia induced by intrathecal HIV-1 envelope glycoprotein gp120.
Authors: Schoeniger-Skinner DK, Ledeboer A, Frank MG, Milligan ED, Poole S, Martin D, Maier SF, Watkins LR
Brain Behav. Immun., 2007-01-03;21(5):660-7.
Species: Rat
Sample Types: CSF
-
Bacterial translocation is downregulated by anti-TNF-alpha monoclonal antibody administration in rats with cirrhosis and ascites.
Authors: Frances R, Chiva M, Sanchez E, Gonzalez-Navajas JM, Llovet T, Zapater P, Soriano G, Munoz C, Balanzo J, Perez-Mateo M, Song XY, Guarner C, Such J
J. Hepatol., 2006-12-27;46(5):797-803.
Species: Rat
Sample Types: Serum
-
Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage.
Authors: Yang S, Hu S, Choudhry MA, Rue LW, Bland KI, Chaudry IH
J. Mol. Cell. Cardiol., 2006-12-16;42(3):620-30.
Species: Rat
Sample Types: Plasma
-
Anti-inflammatory effects of inhaled nitric oxide are optimized at lower oxygen concentration in experimental Klebsiella pneumoniae pneumonia.
Authors: Sun Z, Sun B, Wang X, Wang W, Zhu L
Inflamm. Res., 2006-10-01;55(10):430-40.
Species: Rat
Sample Types: Tissue Homogenates
-
P2Y1 receptor-evoked glutamate exocytosis from astrocytes: control by tumor necrosis factor-alpha and prostaglandins.
Authors: Domercq M, Brambilla L, Pilati E, Marchaland J, Volterra A, Bezzi P
J. Biol. Chem., 2006-08-01;281(41):30684-96.
Species: Rat
Sample Types: Cell Culture Supernates
-
Doxycycline reduces mortality and injury to the brain and cochlea in experimental pneumococcal meningitis.
Authors: Meli DN, Coimbra RS, Erhart DG, Loquet G, Bellac CL, Tauber MG, Neumann U, Leib SL
Infect. Immun., 2006-07-01;74(7):3890-6.
Species: Rat
Sample Types: CSF
-
Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure.
Authors: Holly MK, Dear JW, Hu X, Schechter AN, Gladwin MT, Hewitt SM, Yuen PS, Star RA
Kidney Int., 2006-06-07;70(3):496-506.
Species: Rat
Sample Types: Serum
-
Glucosamine administration during resuscitation improves organ function after trauma hemorrhage.
Authors: Yang S, Zou LY, Bounelis P, Chaudry I, Chatham JC, Marchase RB
Shock, 2006-06-01;25(6):600-7.
Species: Rat
Sample Types: Serum
-
Resuscitation from experimental heatstroke by estrogen therapy.
Authors: Chen SH, Chang FM, Niu KC, Lin MY, Lin MT
Crit. Care Med., 2006-04-01;34(4):1113-8.
Species: Rat
Sample Types: Serum
-
Effects of gabexate mesilate on serum inflammatory cytokines in rats with acute necrotizing pancreatitis.
Authors: Chen CC, Wang SS, Tsay SH, Lee FY, Lu RH, Chang FY, Lee SD
Cytokine, 2006-02-10;33(2):95-9.
Species: Rat
Sample Types: Serum
-
Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat.
Authors: Hofstetter C, Flondor M, Hoegl S, Muhl H, Zwissler B
Crit. Care Med., 2005-10-01;33(10):2317-22.
Species: Rat
Sample Types: BALF, Plasma
-
Prophylactic adenovirus-mediated human kallistatin gene therapy suppresses rat arthritis by inhibiting angiogenesis and inflammation.
Authors: Wang CR, Chen SY, Wu CL, Liu MF, Jin YT, Chao L, Chao J
Arthritis Rheum., 2005-04-01;52(4):1319-24.
Species: Rat
Sample Types: Tissue Homogenates
-
Effects of pyrrolidine dithiocarbamate, an NF-kappaB inhibitor, on cytokine expression and ocular inflammation in experimental autoimmune anterior uveitis.
Authors: Fang IM, Yang CH, Lin CP, Yang CM, Chen MS
J Ocul Pharmacol Ther, 2005-04-01;21(2):95-106.
Species: Rat
Sample Types: Aqueous Humor
-
Developmental changes induced by graded prenatal systemic hypoxic-ischemic insults in rats.
Authors: Robinson S, Petelenz K, Li Q, Cohen ML, Dechant A, Tabrizi N, Bucek M, Lust D, Miller RH
Neurobiol. Dis., 2005-04-01;18(3):568-81.
Species: Rat
Sample Types: Tissue Homogenates
-
Suppression of autoimmune retinal disease by lovastatin does not require Th2 cytokine induction.
Authors: Gegg ME, Harry R, Hankey D, Zambarakji H, Pryce G, Baker D, Adamson P, Calder V, Greenwood J
J. Immunol., 2005-02-15;174(4):2327-35.
Species: Rat
Sample Types: Cell Culture Supernates
-
Tumor necrosis factor alpha expression and protein levels after fluid percussion injury in rats: the effect of injury severity and brain temperature.
Authors: Vitarbo EA, Chatzipanteli K, Kinoshita K, Truettner JS, Alonso OF, Dietrich WD
Neurosurgery, 2004-08-01;55(2):416-24; discu.
Species: Rat
Sample Types: Serum
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HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS).
Authors: Holguin A, O'Connor KA, Biedenkapp J, Campisi J, Wieseler-Frank J, Milligan ED, Hansen MK, Spataro L, Maksimova E, Bravmann C, Martin D, Fleshner M, Maier SF, Watkins LR
Pain, 2004-08-01;110(3):517-30.
Species: Rat
Sample Types: CSF
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Anti-inflammatory effects of alpha-melanocyte-stimulating hormone against rat endotoxin-induced uveitis and the time course of inflammatory agents in aqueous humor.
Authors: Nishida T, Miyata S, Itoh Y, Mizuki N, Ohgami K, Shiratori K, Ilieva IB, Ohno S, Taylor AW
Int. Immunopharmacol., 2004-08-01;4(8):1059-66.
Species: Rat
Sample Types: Aqueous Humor
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Insulin treatment improves hepatic morphology and function through modulation of hepatic signals after severe trauma.
Authors: Schubert T, Horch RE
Ann. Surg., 2004-08-01;240(2):340-9.
Species: Rat
Sample Types: Tissue Homogenates
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Ameliorating effects of the immunomodulator 3-(2-ethylphenyl)-5-(3-methoxyphenyl)-1H-1,2,4-triazole in an experimental model of colitis in the rat.
Authors: Stasi MA, Ruggiero V, Ursillo A, Taurelli R, Agliano M, Weber E, Lorenzoni P, Sorrentino V, Pacifici L, Carminati P
Eur. J. Pharmacol., 2004-06-28;494(2):263-72.
Species: Rat
Sample Types: Tissue Homogenates
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Insulin attenuates the systemic inflammatory response in endotoxemic rats.
Authors: Jeschke MG, Klein D, Bolder U, Einspanier R
Endocrinology, 2004-06-10;145(9):4084-93.
Species: Rat
Sample Types: Tissue Homogenates
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Gene transfer of tumor necrosis factor inhibitor improves the function of lung allografts.
Authors: Tagawa T, Kozower BD, Kanaan SA, Daddi N, Muraoka M, Oka T, Ritter JH, Patterson GA
J. Thorac. Cardiovasc. Surg., 2004-06-01;127(6):1558-63.
Species: Rat
Sample Types: Tissue Homogenates
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A method for measuring multiple cytokines from small samples.
Authors: O'Connor KA
Brain Behav. Immun., 2004-05-01;18(3):274-80.
Species: Rat
Sample Types: CSF
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Oral (gavage), in utero and post-natal exposure of Sprague-Dawley rats to low doses of tributyltin chloride. Part II: effects on the immune system.
Authors: Tryphonas H, Cooke G, Caldwell D, Bondy G, Parenteau M, Hayward S, Pulido O
Food Chem. Toxicol., 2004-02-01;42(2):221-35.
Species: Rat
Sample Types: Serum
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Alveolar macrophage cytotoxicity for normal lung fibroblasts is mediated by nitric oxide release.
Authors: Morgan DL, Shines CJ
Toxicol In Vitro, 2004-02-01;18(1):139-46.
Species: Rat
Sample Types: Cell Culture Supernates
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Differential cytokine response in interstitial fluid in skin and serum during experimental inflammation in rats.
Authors: Nedrebo T, Reed RK, Jonsson R, Berg A, Wiig H
J. Physiol. (Lond.), 2004-01-14;556(0):193-202.
Species: Rat
Sample Types: Interstitial Fluid
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Differential expression of cytokine genes and inducible nitric oxide synthase induced by opacity phenotype variants of Streptococcus pneumoniae during acute otitis media in the rat.
Authors: Long JP, Tong HH, Shannon PA, DeMaria TF
Infect. Immun., 2003-10-01;71(10):5531-40.
Species: Rat
Sample Types: Tissue Secretion
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Iron intake increases infarct volume after permanent middle cerebral artery occlusion in rats.
Authors: Castellanos M, Puig N, Carbonell T, Castillo J, Martinez J, Rama R, Davalos A
Brain Res., 2002-10-11;952(1):1-6.
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Recipient intramuscular cotransfection of naked plasmid transforming growth factor beta1 and interleukin 10 ameliorates lung graft ischemia-reperfusion injury.
Authors: D'Ovidio F
J. Thorac. Cardiovasc. Surg., 2002-08-01;124(2):259-69.
Species: Rat
Sample Types: BALF
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Differential effects of ebselen on neutrophil recruitment, chemokine, and inflammatory mediator expression in a rat model of lipopolysaccharide-induced pulmonary inflammation.
Authors: Haddad el-B, McCluskie K, Birrell MA, Dabrowski D, Pecoraro M, Underwood S, Chen B, De Sanctis GT, Webber SE, Foster ML, Belvisi MG
J. Immunol., 2002-07-15;169(2):974-82.
Species: Rat
Sample Types: BALF
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Gene transfer of transforming growth factor-beta1 to the rat peritoneum: effects on membrane function.
Authors: Margetts PJ, Kolb M, Galt T, Hoff CM, Shockley TR, Gauldie J
J. Am. Soc. Nephrol., 2001-10-01;12(10):2029-39.
Species: Rat
Sample Types: Peritoneal Fluid
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Excellent kit worked for rat placenta tissue lysate.
We tested TNF-alpha levels in homogenized rat spinal cord. The standard curve was excellent and the CV values were all very low. We have used kits from other companies and found RnD systems kits to be superior to all other companies. The kits from RnD systems result in much lower background levels and much lower CV levels, which really helps with consistency and repeatability. The image shows the standard curve and the green outlines the low CV values from a run containing homogenized rat spinal cord.