Quantikine Immunoassay Control 1032 for Human HS Granzyme B

Catalog #: QC274 Datasheet / COA / SDS

For use with catalog number HSGZB0

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QC274

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All Granzyme B ELISAs

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Quantikine Immunoassay Control 1032 for Human HS Granzyme B Summary

Specifications

Storage

Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Applications

Control

Species

Human

Product Datasheets

COA

SDS

Background: Granzyme B

Granzyme family serine proteases are stored in the granules of cytotoxic T lymphocytes and natural killer cells. Granzymes contain one S1 protease domain and are synthesized as preproproteins. Granzymes are released toward pathogen infected or transformed target cells during cellular immune reactions. Target cell entry by granzymes is through perforin channels. Granzymes trigger apoptosis by caspase-dependent and -independent mechanisms. There are five granzymes (A, B, G, H and K) in human and many more in mouse and rat.

Entrez Gene IDs

3002 (Human); 14939 (Mouse)

Alternate Names

C11; CCPI; CGL1; CGL-1; CSPB; CSP-B; CTLA1; CTLA-1; CTSGL1; Fragmentin-2; Granzyme B; Granzyme-2; GranzymeB; GRB; GrzB; GZMB; HLP; SECT