Pentobarbital sodium salt

Name: Pentobarbital sodium salt
Brand: Tocris Bioscience
SKU: 4579
Price: 89 USD

Catalog #: 4579
6 Citations Datasheet / COA / SDS

Discontinued Product

4579 has been discontinued.

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Pentobarbital sodium salt | CAS No. 57-33-0 | Additional GABA Compounds

1 Image

Description: Enhances GABAergic activity

Chemical Name: 5-Ethyl-5-(1-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione sodium salt

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Product Details

Citations (6)

Reviews

Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

Pentobarbital sodium salt enhances GABAergic activity. Pentobarbital is a short-acting barbiturate.

Technical Data

M.Wt:

248.25

Formula:

C₁₁H₁₇N₂NaO₃

Solubility:

Soluble to 100 mM in water

Storage:

Store at RT

CAS No:

57-33-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

Oral kanglaite injection (KLTI) attenuates the lung cancer-promoting effect of high-fat diet (HFD)-induced obesity
N Cao, X Ma, Z Guo, Y Zheng, S Geng, M Meng, Z Du, H Lin, Y Duan, G Du
Oncotarget, 2016;7(38):61093-61106.
Modulation of GABA_A receptor channel gating by pentobar.
Steinbach and Akk
J.Physiol., 2001;537:715
Trigeminal Nerve Electrical Stimulation: An Effective Arousal Treatment for Loss of Consciousness
Y Zheng, S Wu, Q Yang, Z Xu, S Zhang, S Fan, C Liu, X Li, C Ma
Brain research bulletin, 2021;169(0):81-93.

Product Datasheets

Certificate of Analysis is currently unavailable on-line. Please contact Customer Service

SDS

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Mass

Concentration

Volume

M. Wt* g/mol

*When preparing stock solutions always use the batch-specific molecular weight of the product found on the vial label and CoA (available online).

Citations for Pentobarbital sodium salt

The citations listed below are publications that use Tocris products. Selected citations for Pentobarbital sodium salt include:

6 Citations: Showing 1 - 6

Intravitreal Short-Hairpin RNA Attenuated Adeno-Associated Virus-Induced Knockdown of Amphiregulin and Axial Elongation in Experimental Myopia.
Authors: Jost B Et al.
Invest Ophthalmol Vis Sci 2023;64:11
Upregulation of miR-144-3p alleviates Doxorubicin-induced heart failure and cardiomyocytes apoptosis via SOCS2/PI3K/AKT axis.
Authors: Xueyu Et al.
Chem Biol Drug Des 2023;101:24-39
In vivo Imaging of Retina and Choroid in Guinea Pigs.
Authors: Jost B Et al.
Front Med (Lausanne) 2021;8:730494
The P300/XBP1s/Herpud1 axis promotes macrophage M2 polarization and the development of choroidal neovascularization.
Authors: Ying Et al.
J Cell Mol Med 2021;25:6709-6720
Disruption of Cholinergic Circuits as an Area for Targeted Drug Treatment of Alzheimer's Disease: In Vivo Assessment of Short-Term Plasticity in Rat Brain.
Authors: Konstantin Et al.
Pharmaceuticals (Basel) 2020;13
MicroRNA-34a affects chondrocyte apoptosis and proliferation by targeting the SIRT1/p53 signaling pathway during the pathogenesis of osteoarthritis.
Authors: Yan Et al.
Nat Commun 2016;38:201

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