PAG 3'-fluoro-4'-piperazine

Catalog # Availability Size / Price Qty
7994/25
PAG 3'-fluoro-4'-piperazine | Degrader Building Blocks
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Description: Functionalized cereblon ligand for PROTAC development

Chemical Name: 3-[[3-Fluoro-4-(1-piperazinyl)phenyl]amino]-2,6-piperidinedione dihydrochloride

Purity: ≥95%

Product Details
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Biological Activity

Phenyl amino glutarimide (PAG) 3'-fluoro-4'-piperazine is a functionalized cereblon ligand for PROTAC® research and development; incorporates an E3 ligase ligand with a terminal piperazine for onward chemistry to generate Protein Degraders with rigid linkers. Part of a range of functionalized tool molecules for PROTAC® Degrader R&D.

Please contact us for SD files of our available Degrader Building Blocks.

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.

Usage Guidelines

This product is provided for use in onward chemistry. Suitable solvents can be used.

Technical Data

M.Wt:
379.26
Formula:
C15H19FN4O2.2HCl
Purity:
≥95%
Storage:
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

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