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O8 OGG1 Inhibitor

Catalog #: 6236
1 Citation Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6236/5
6236/25
O8 OGG1 Inhibitor | CAS No. 350997-39-6 | Glycosylase Inhibitors
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Description: Potent and selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor

Chemical Name: 3,4-Dichlorobenzo[b]thiophene-2-carbohydrazide

Purity: ≥98%

Product Details
Citations (1)
Reviews
Biological Activity Technical Data Background Product Datasheets Calculators

Biological Activity

O8 OGG1 Inhibitor is a potent and selective 8-oxoguanine DNA glycosylase 1 (OGG1) inhibitor (IC50 = 0.2 μM in a gel based assay). Exhibits > 200-fold selectivity for OGG1 over other DNA glycosylases, NEIL1 and NTH1.

Technical Data

M.Wt:
261.13
Formula:
C9H6Cl2N2OS
Solubility:
Soluble to 100 mM in DMSO
Purity:
≥98%
Storage:
Store at +4°C
CAS No:
350997-39-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Background References

  1. Small molecule inhibitors of 8-oxoguanine DNA glycosylase-1 (OGG1).
    Donley et al.
    ACS Chem.Biol., 2015;10:2334

Product Datasheets

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Citation for O8 OGG1 Inhibitor

The citations listed below are publications that use Tocris products. Selected citations for O8 OGG1 Inhibitor include:

1 Citation: Showing 1 - 1

  1. Ginkgolic Acid Inhibits Coronavirus Strain 229E Infection of Human Epithelial Lung Cells.
    Authors: Gustavo F Et al.
    Pharmaceuticals (Basel)  2021;14

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