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NVS PAK1 C

Catalog #: 6133 Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
6133/25
6133/5
NVS PAK1 C | CAS No. 2250019-95-3 | PAK Inhibitors
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Description: Negative control of NVS PAK1 1 (Cat. No. 6132)

Chemical Name: (3S)-3-(2-Chloro-5-(2,2-difluoroethyl)-8-fluoro-5H-dibenzo[b,e][1,4]diazepin-11-ylamino)-N,N-dimethylpyrrolidine-1-carboxamide

Purity: ≥98%

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Biological Activity

NVS PAK1 C is a negative control of NVS PAK1 1 (Cat. No. 6132), a potent and selective PAK1 inhibitor.

Technical Data

M.Wt:
465.91
Formula:
C22H23ClF3N5O
Solubility:
Soluble to 100 mM in DMSO and to 20 mM in ethanol
Purity:
≥98%
Storage:
Store at -20°C
CAS No:
2250019-95-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Additional Information

Licensing Caveats:
This probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the NVS PAK1 1 probe summary on the SGC website.

Background References

  1. Optimization of a dibenzodiazepine hit to a potent and selective allosteric PAK1 inhibitor.
    Karpov et al.
    ACS Med.Chem.Lett, 2015;6:776

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