NNC 63-0532
Chemical Name: 8-(1-Naphthalenylmethyl)-4-oxo-1-phenyl-1,3,8-triazaspiro[4.5]decane-3-acetic acid, methyl ester
Purity: ≥98%
Biological Activity
NNC 63-0532 is a potent non-peptide agonist for the NOP receptor (EC50 = 305 nM, Ki = 7.3 nM); ~ 12-fold selective over other receptors. Centrally active following systemic administration in vivo.Technical Data
The technical data provided above is for guidance only.
For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.
Background References
-
(8-Naphthalen-1-ylmethyl-4-oxo-1-phenyl-1,3,8-triaza-spiro[4.5]-dec-3-yl)-acetic acid methyl ester (NNC 63-0532) is a novel potent nociceptin receptor agonist.
Thomsen and Hohlweg
Br.J.Pharmacol., 2000;131:903
Product Datasheets
Reconstitution Calculator
Molarity Calculator
Citation for NNC 63-0532
The citations listed below are publications that use Tocris products. Selected citations for NNC 63-0532 include:
1 Citation: Showing 1 - 1
-
NOP receptor mediates anti-analgesia induced by agonist-antagonist opioids.
Authors: Gear Et al.
Neuroscience 2014;257:139
FAQs
No product specific FAQs exist for this product, however you may
View all Small Molecule FAQsReviews for NNC 63-0532
There are currently no reviews for this product. Be the first to review NNC 63-0532 and earn rewards!
Have you used NNC 63-0532?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image