Mouse IL-28 R alpha/IFN-lambda R1 NP_777276 VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC1599
R&D Systems VersaClone cDNA Plasmids
1 Image
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Mouse IL-28 R alpha/IFN-lambda R1 NP_777276 VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Mouse

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Background: IL-28 R alpha/IFN-lambda R1

IL-28 receptor alpha subunit, also named interferon-lambda R1, is a type I transmembrane glycoprotein that is cytokine receptor family 2 member 12 (CRF2-12). It pairs with the IL-10 receptor beta subunit (IL-10 R beta, CRF2-4) to form the IL-28 R. This receptor interacts with the interferon-like cytokines (type III interferons) IL-28A (IFN-lambda 2), IL-28B (IFN-lambda 3) and IL-29 (IFN-lambda 1). Signaling through IL-28 R alpha results in upregulated expression of MHC class I antigens and anti-viral, anti-proliferative and anti-tumor activity.

Long Name
Interleukin 28 Receptor alpha
Entrez Gene IDs
163702 (Human); 242700 (Mouse); 362628 (Rat)
Alternate Names
class II cytokine receptor CRF2/12; CRF2/12; CRF2-12; Cytokine receptor class-II member 12; Cytokine receptor family 2 member 12; IFN-lambda R1; IFN-lambda receptor 1; IFN-lambda-R1; IFNLR; IFNLR1; IL-28 R alpha; IL-28 receptor subunit alpha; IL28R alpha; IL-28R1; IL28RA; IL-28Ra; IL-28R-alpha; Interferon lambda receptor 1; interferon lambda, receptor 1; interleukin 28 receptor A; interleukin 28 receptor, alpha (interferon, lambda receptor); interleukin 28 receptor, alpha; interleukin or cytokine receptor 2; interleukin-28 receptor subunit alpha; LICR2; Likely interleukin or cytokine receptor 2

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