Home / IL-1 beta/IL-1F2 / Mouse IL-1 beta/IL-1F2 DuoSet ELISA

Mouse IL-1 beta/IL-1F2 DuoSet ELISA

Catalog #: DY401
489 Citations 34 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
DY401
DY401-05
Ancillary Products Available
DY008B: DuoSet ELISA Ancillary Reagent Kit 2
DY999B: Substrate Reagent Pack
DY999: Substrate Reagent Pack
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Mouse IL-1 beta / IL-1F2 ELISA Standard Curve
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Citations (489)
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Summary Product Features Kit Content Other Reagents Required Data Examples Product Datasheets Preparation and Storage Background

Mouse IL-1 beta/IL-1F2 DuoSet ELISA Summary

Assay Type
Solid Phase Sandwich ELISA
Format
96-well strip plate
Sample Volume Required
100 µL
Assay Range
15.6 - 1,000 pg/mL
Sufficient Materials
For five or fifteen 96-well plates*
Specificity
Please see the product datasheet

* Provided that the recommended microplates, buffers, diluents, substrates and solutions are used, and the assay is run as summarized in the Assay Procedure provided.

This DuoSet ELISA Development kit contains the basic components required for the development of sandwich ELISAs to measure natural and recombinant mouse IL-1 beta/IL-1F2. The suggested diluent is suitable for the analysis of most cell culture supernate samples. Diluents for complex matrices, such as serum and plasma, should be evaluated prior to use in this DuoSet.

Product Features

  • Optimized capture and detection antibody pairings with recommended concentrations save lengthy development time
  • Development protocols are provided to guide further assay optimization
  • Assay can be customized to your specific needs
  • Economical alternative to complete kits

Kit Content

  • Capture Antibody
  • Detection Antibody
  • Recombinant Standard
  • Streptavidin conjugated to horseradish-peroxidase (Streptavidin-HRP)

Other Reagents Required

DuoSet Ancillary Reagent Kit 2 (5 plates): (Catalog # DY008) containing 96 well microplates, plate sealers, substrate solution, stop solution, plate coating buffer (PBS), wash buffer, and Reagent Diluent Concentrate 2.

The components listed above may be purchased separately:

PBS: (Catalog # DY006), or 137 mM NaCl, 2.7 mM KCl, 8.1 mM Na2HPO4, 1.5 mM KH2PO4, pH 7.2 - 7.4, 0.2 µm filtered

Wash Buffer: (Catalog # WA126), or 0.05% Tween® 20 in PBS, pH 7.2-7.4

Reagent Diluent: (Catalog # DY995), or 1% BSA in PBS, pH 7.2-7.4, 0.2 µm filtered

Substrate Solution: 1:1 mixture of Color Reagent A (H2O2) and Color Reagent B (Tetramethylbenzidine) (Catalog # DY999)

Stop Solution: 2 N H2SO4 (Catalog # DY994)

Microplates: R&D Systems (Catalog # DY990)

Plate Sealers: ELISA Plate Sealers (Catalog # DY992)

 

Scientific Data

N/A Mouse IL-1 beta / IL-1F2 ELISA Standard Curve View Larger

Mouse IL-1 beta / IL-1F2 ELISA Standard Curve

ELISA Detection of Mouse IL-1 beta/IL-1F2 by ELISA View Larger

Detection of Mouse IL-1 beta/IL-1F2 by ELISA Exosomal release of IL-1 alpha by neutrophils(A) Representative confocal images of peritoneal neutrophils stimulated with LPS or curdlan for 6 h.(B) Quantification of IL-1 alpha and CD63 co-localization using ImageJ (each data point represents a single cell).(C) NTA of EV size distribution and concentration.(D–G) Neutrophils were stimulated in the presence of exosome inhibitor GW4869, and IL-1 alpha and IL-1 beta were quantified by ELISA in isolated EVs following lysis (D and F) and in total cell-free supernatants (E and G).(H) Inhibition of EV secretion shown by NTA.(I) Bioactive IL-1 signaling through IL-1R1 reporter cells was measured in isolated exosomes in the absence of detergent lysis (n = 4). Neutralizing antibodies (Abs) to IL-1 alpha, IL-1 beta, or both cytokines were included in the reporter assay, and bioactive cytokine concentration was calculated based on a standard curve using recombinant IL-1 alpha and IL-1 beta.Two-way ANOVA with Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Experiments in (A) and (B) were repeated three times; (C)–(G) are biological replicates from repeat experiments. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/34010648), licensed under a CC-BY license. Not internally tested by R&D Systems.

ELISA Detection of Mouse IL-1 beta/IL-1F2 by ELISA View Larger

Detection of Mouse IL-1 beta/IL-1F2 by ELISA Exosomal release of IL-1 alpha by neutrophils(A) Representative confocal images of peritoneal neutrophils stimulated with LPS or curdlan for 6 h.(B) Quantification of IL-1 alpha and CD63 co-localization using ImageJ (each data point represents a single cell).(C) NTA of EV size distribution and concentration.(D–G) Neutrophils were stimulated in the presence of exosome inhibitor GW4869, and IL-1 alpha and IL-1 beta were quantified by ELISA in isolated EVs following lysis (D and F) and in total cell-free supernatants (E and G).(H) Inhibition of EV secretion shown by NTA.(I) Bioactive IL-1 signaling through IL-1R1 reporter cells was measured in isolated exosomes in the absence of detergent lysis (n = 4). Neutralizing antibodies (Abs) to IL-1 alpha, IL-1 beta, or both cytokines were included in the reporter assay, and bioactive cytokine concentration was calculated based on a standard curve using recombinant IL-1 alpha and IL-1 beta.Two-way ANOVA with Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Experiments in (A) and (B) were repeated three times; (C)–(G) are biological replicates from repeat experiments. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/34010648), licensed under a CC-BY license. Not internally tested by R&D Systems.

ELISA Detection of Mouse IL-1 beta/IL-1F2 by ELISA View Larger

Detection of Mouse IL-1 beta/IL-1F2 by ELISA Exosomal release of IL-1 alpha by neutrophils(A) Representative confocal images of peritoneal neutrophils stimulated with LPS or curdlan for 6 h.(B) Quantification of IL-1 alpha and CD63 co-localization using ImageJ (each data point represents a single cell).(C) NTA of EV size distribution and concentration.(D–G) Neutrophils were stimulated in the presence of exosome inhibitor GW4869, and IL-1 alpha and IL-1 beta were quantified by ELISA in isolated EVs following lysis (D and F) and in total cell-free supernatants (E and G).(H) Inhibition of EV secretion shown by NTA.(I) Bioactive IL-1 signaling through IL-1R1 reporter cells was measured in isolated exosomes in the absence of detergent lysis (n = 4). Neutralizing antibodies (Abs) to IL-1 alpha, IL-1 beta, or both cytokines were included in the reporter assay, and bioactive cytokine concentration was calculated based on a standard curve using recombinant IL-1 alpha and IL-1 beta.Two-way ANOVA with Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Experiments in (A) and (B) were repeated three times; (C)–(G) are biological replicates from repeat experiments. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/34010648), licensed under a CC-BY license. Not internally tested by R&D Systems.

ELISA Detection of Mouse IL-1 beta/IL-1F2 by ELISA View Larger

Detection of Mouse IL-1 beta/IL-1F2 by ELISA Exosomal release of IL-1 alpha by neutrophils(A) Representative confocal images of peritoneal neutrophils stimulated with LPS or curdlan for 6 h.(B) Quantification of IL-1 alpha and CD63 co-localization using ImageJ (each data point represents a single cell).(C) NTA of EV size distribution and concentration.(D–G) Neutrophils were stimulated in the presence of exosome inhibitor GW4869, and IL-1 alpha and IL-1 beta were quantified by ELISA in isolated EVs following lysis (D and F) and in total cell-free supernatants (E and G).(H) Inhibition of EV secretion shown by NTA.(I) Bioactive IL-1 signaling through IL-1R1 reporter cells was measured in isolated exosomes in the absence of detergent lysis (n = 4). Neutralizing antibodies (Abs) to IL-1 alpha, IL-1 beta, or both cytokines were included in the reporter assay, and bioactive cytokine concentration was calculated based on a standard curve using recombinant IL-1 alpha and IL-1 beta.Two-way ANOVA with Tukey’s multiple comparisons test. *p < 0.05, **p < 0.01, ***p < 0.001, ****p < 0.0001. Experiments in (A) and (B) were repeated three times; (C)–(G) are biological replicates from repeat experiments. Image collected and cropped by CiteAb from the following publication (https://pubmed.ncbi.nlm.nih.gov/34010648), licensed under a CC-BY license. Not internally tested by R&D Systems.

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Preparation and Storage

Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-1 beta/IL-1F2

The Interleukin 1 (IL-1) family of proteins consists of IL-1 alpha, IL-1 beta, and the IL-1 receptor antagonist (IL-1ra). IL-1 alpha and IL-1 beta bind to the same cell surface receptors and share biological functions (1). IL-1 is not produced by unstimulated cells of healthy individuals with the exception of skin keratinocytes, some epithelial cells, and certain cells of the central nervous system. However, in response to inflammatory agents, infections, or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cell types is seen. IL-1 beta plays a central role in immune and inflammatory responses, bone remodeling, fever, carbohydrate metabolism, and GH/IGF-I physiology. Inappropriate or prolonged production of IL-1 has been implicated in a variety of pathological conditions including sepsis, rheumatoid arthritis, inflammatory bowel disease, acute and chronic myelogenous leukemia, insulindependent diabetes mellitus, atherosclerosis, neuronal injury, and aging-related diseases (2-5). 

 IL-1 alpha and IL-1 beta are structurally related polypeptides that show approximately 25% homology at the amino acid (aa) level. Both are synthesized as 31 kDa precursors that are subsequently cleaved into mature proteins of approximately 17.5 kDa (6, 7). Cleavage of the IL-1 beta precursor by Caspase-1/ICE is a key step in the inflammatory response (2, 8). Neither IL-1 alpha nor IL-1 beta contains a typical hydrophobic signal peptide (9-11), but evidence suggests that these factors can be secreted by non-classical pathways (12, 13). A portion of unprocessed IL-1 alpha can be presented on the cell membrane and may retain biological activity (14). The precursor form of IL-1 beta, unlike the IL-1 alpha precursor, shows little or no biological activity in comparison to the processed form (13, 15). Both unprocessed and mature forms of IL-1 beta are exported from the cell. 
 IL-1 alpha and IL-1 beta exert their effects through immunoglobulin superfamily receptors that additionally bind IL-1ra. The 80 kDa transmembrane type I receptor (IL-1 RI) is expressed on T cells, fibroblasts, keratinocytes, endothelial cells, synovial lining cells, chondrocytes, and hepatocytes (16, 17). The 68 kDa transmembrane type II receptor (IL-1 RII) is expressed on B cells, neutrophils, and bone marrow cells (18). The two IL-1 receptor types show approximately 28% homology in their extracellular domains but differ significantly in that the type II receptor has a cytoplasmic domain of only 29 aa, whereas the type I receptor has a 213 aa cytoplasmic domain. IL-1 RII does not appear to signal in response to IL-1 and may function as a decoy receptor that attenuates IL-1 function (19). The IL-1 receptor accessory protein (IL-1 RAcP) associates with IL-1 RI and is required for IL-1 RI signal transduction (20). IL-1ra is a secreted molecule that functions as a competitive inhibitor of IL-1 (21, 22). Soluble forms of both IL-1 RI and IL-1 RII have been detected in human plasma, synovial fluids, and the conditioned media of several human cell lines (23, 24). In addition, IL-1 binding proteins that resemble soluble IL-1 RII are encoded by vaccinia and cowpox viruses (25).

Long Name:
Interleukin 1 beta
Entrez Gene IDs:
3553 (Human); 16176 (Mouse); 24494 (Rat); 397122 (Porcine); 403974 (Canine); 100034237 (Equine); 100135556 (Guinea Pig)
Alternate Names:
catabolin; IL1 beta; IL-1 beta; IL-1; IL1B; IL-1b; IL1-BETA; IL-1F2; IL1F2IL-1 beta; interleukin 1, beta; interleukin-1 beta; preinterleukin 1 beta; pro-interleukin-1-beta

Assay Procedure

GENERAL ELISA PROTOCOL

Plate Preparation

  1. Dilute the Capture Antibody to the working concentration in PBS without carrier protein. Immediately coat a 96-well microplate with 100 μL per well of the diluted Capture Antibody. Seal the plate and incubate overnight at room temperature.
  2. Aspirate each well and wash with Wash Buffer, repeating the process two times for a total of three washes. Wash by filling each well with Wash Buffer (400 μL) using a squirt bottle, manifold dispenser, or autowasher. Complete removal of liquid at each step is essential for good performance. After the last wash, remove any remaining Wash Buffer by aspirating or by inverting the plate and blotting it against clean paper towels.
  3. Block plates by adding 300 μL of Reagent Diluent to each well. Incubate at room temperature for a minimum of 1 hour.
  4. Repeat the aspiration/wash as in step 2. The plates are now ready for sample addition.

Assay Procedure

  1. Add 100 μL of sample or standards in Reagent Diluent, or an appropriate diluent, per well. Cover with an adhesive strip and incubate 2 hours at room temperature.
  2. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  3. Add 100 μL of the Detection Antibody, diluted in Reagent Diluent, to each well. Cover with a new adhesive strip and incubate 2 hours at room temperature.
  4. Repeat the aspiration/wash as in step 2 of Plate Preparation.
  5. Add 100 μL of the working dilution of Streptavidin-HRP to each well. Cover the plate and incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  6. Repeat the aspiration/wash as in step 2.
  7. Add 100 μL of Substrate Solution to each well. Incubate for 20 minutes at room temperature. Avoid placing the plate in direct light.
  8. Add 50 μL of Stop Solution to each well. Gently tap the plate to ensure thorough mixing.
  9. Determine the optical density of each well immediately, using a microplate reader set to 450 nm. If wavelength correction is available, set to 540 nm or 570 nm. If wavelength correction is not available, subtract readings at 540 nm or 570 nm from the readings at 450 nm. This subtraction will correct for optical imperfections in the plate. Readings made directly at 450 nm without correction may be higher and less accurate.

Citations for Mouse IL-1 beta/IL-1F2 DuoSet ELISA

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

489 Citations: Showing 1 - 10
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  1. Cav3.2 channel regulates cerebral ischemia/reperfusion injury: a promising target for intervention
    Authors: Dai, F;Hu, C;Li, X;Zhang, Z;Wang, H;Zhou, W;Wang, J;Geng, Q;Dong, Y;Tang, C;
    Neural regeneration research
    Species: Mouse
    Sample Types: Tissue Homogenates
  2. A palmitoylation-depalmitoylation relay spatiotemporally controls GSDMD activation in pyroptosis
    Authors: Zhang, N;Zhang, J;Yang, Y;Shan, H;Hou, S;Fang, H;Ma, M;Chen, Z;Tan, L;Xu, D;
    Nature cell biology
    Species: Mouse
    Sample Types: Serum, Cell Culture Supernates
  3. LRRK2 G2019S Promotes Colon Cancer Potentially via LRRK2-GSDMD Axis-Mediated Gut Inflammation
    Authors: Wang, Y;Gao, JZ;Sakaguchi, T;Maretzky, T;Gurung, P;Narayanan, NS;Short, S;Xiong, Y;Kang, Z;
    Cells
    Species: Transgenic Mouse
    Sample Types: Cell Culture Supernates
  4. Targeting terminal pathway reduces brain complement activation, amyloid load and synapse loss, and improves cognition in a mouse model of dementia
    Authors: Zelek, WM;Bevan, RJ;Morgan, BP;
    Brain, behavior, and immunity
    Species: Mouse
    Sample Types: Serum
  5. Species-specific NLRP3 regulation and its role in CNS autoinflammatory diseases
    Authors: Koller, BH;Nguyen, M;Snouwaert, JN;Gabel, CA;Ting, JP;
    Cell reports
    Species: Mouse
    Sample Types: Cell Culture Supernates, BALF
  6. Panaxydol extracted from Panax ginseng inhibits NLRP3 inflammasome activation to ameliorate NASH-induced liver injury
    Authors: Kim, MY;Jeong, B;Lee, GS;Jeon, H;Yang, YM;Yang, H;Han, YH;
    International immunopharmacology
    Species: Mouse
    Sample Types: Cell Culture Supernates
  7. IFN-?3 is induced by Leishmania donovani and can inhibit parasite growth in cell line models but not in the mouse model, while it shows a significant association with leishmaniasis in humans
    Authors: De, M;Sukla, S;Bharatiya, S;Keshri, S;Roy, DG;Roy, S;Dutta, D;Saha, S;Ejazi, SA;Ravichandiran, V;Ali, N;Chatterjee, M;Chinnaswamy, S;
    Infection and immunity
    Species: Mouse
    Sample Types: Cell Culture Supernates
  8. GM-CSF-mediated epithelial-immune cell crosstalk orchestrates pulmonary immunity to Aspergillus fumigatus
    Authors: Mills, KAM;Westermann, F;Espinosa, V;Rosiek, E;Desai, JV;Aufiero, MA;Guo, Y;Mitchell, KA;Tuzlak, S;De Feo, D;Lionakis, MS;Rivera, A;Becher, B;Hohl, TM;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Tissue Homogenates
  9. Dihydrothiazolo ring-fused 2-pyridone antimicrobial compounds treat Streptococcus pyogenes skin and soft tissue infection
    Authors: Zou, Z;Obernuefemann, CLP;Singh, P;Pinkner, JS;Xu, W;Nye, TM;Dodson, KW;Almqvist, F;Hultgren, SJ;Caparon, MG;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Serum
  10. Central activation of the fatty acid sensor GPR120 suppresses microglia reactivity and alleviates sickness- and anxiety-like behaviors
    Authors: Nakajima, S;Demers, G;Machuca-Parra, AI;Pour, ZD;Bairamian, D;Bouyakdan, K;Fisette, A;Kabahizi, A;Robb, J;Rodaros, D;Laurent, C;Ferreira, G;Arbour, N;Alquier, T;Fulton, S;
    Journal of neuroinflammation
    Species: Mouse
    Sample Types: Cell Culture Supernates
  11. CpsA mediates infection of recruited lung myeloid cells by Mycobacterium tuberculosis
    Authors: Grigsby, SJ;Prasad, GVRK;Wallach, JB;Mittal, E;Hsu, FF;Schnappinger, D;Philips, JA;
    Cell reports
    Species: Mouse
    Sample Types: Tissue Homogenates
  12. Keratin 15 protects against cigarette smoke-induced epithelial mesenchymal transformation by MMP-9
    Authors: Zhu, W;Han, L;Wu, Y;Tong, L;He, L;Wang, Q;Yan, Y;Pan, T;Shen, J;Song, Y;Shen, Y;Zhu, Q;Zhou, J;
    Respiratory research
    Species: Mouse, Transgenic Mouse
    Sample Types: BALF
  13. Discovery of anti-neuroinflammatory agents from 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidin-2-amine derivatives by regulating microglia polarization
    Authors: Yang, Y;Gao, ZF;Hou, GG;Meng, QG;Hou, Y;
    European journal of medicinal chemistry
  14. Discovery of anti-neuroinflammatory agents from 1,4,5,6-tetrahydrobenzo[2,3]oxepino[4,5-d]pyrimidin-2-amine derivatives by regulating microglia polarization
    Authors: Yang, Y;Gao, ZF;Hou, GG;Meng, QG;Hou, Y;
    European journal of medicinal chemistry
    Species: Mouse
    Sample Types: Cell Culture Supernates
  15. A 5-Lipoxygenase Inhibitor, Zileuton, Modulates Host Immune Responses and Improves Lung Function in a Model of Severe Acute Respiratory Syndrome (SARS) Induced by Betacoronavirus
    Authors: Pereira, RDD;Rabelo, RAN;Oliveira, NFM;Porto, SLT;Andrade, ACDSP;Queiroz-Junior, CM;Barbosa, CLN;de Souza-Costa, LP;Santos, FRDS;Oliveira, FBR;da Silva, BLV;Umezu, HL;Ferreira, R;da Silva, GSF;Cruz, JS;Teixeira, MM;Costa, VV;Machado, FS;
    Viruses
    Species: Mouse
    Sample Types: Tissue Homogenates
  16. Chronic hyperpalatable diet induces impairment of hippocampal-dependent memories and alters glutamatergic and fractalkine axis signaling
    Authors: Ribeiro, R;Silva, EG;Moreira, FC;Gomes, GF;Cussat, GR;Silva, BSR;da Silva, MCM;de Barros Fernandes, H;de Sena Oliveira, C;de Oliveira Guarnieri, L;Lopes, V;Ferreira, CN;de Faria, AMC;Maioli, TU;Ribeiro, FM;de Miranda, AS;Moraes, GSP;de Oliveira, ACP;Vieira, LB;
    Scientific reports
    Species: Mouse
    Sample Types: Serum, Tissue Homogenates
  17. Effector memory T cells induce innate inflammation by triggering DNA damage and a non-canonical STING pathway in dendritic cells
    Authors: Meibers, HE;Warrick, KA;VonHandorf, A;Vallez, CN;Kawarizadeh, K;Saha, I;Donmez, O;Jain, VG;Kottyan, LC;Weirauch, MT;Pasare, C;
    Cell reports
    Species: Mouse
    Sample Types: Serum
  18. Inflammasome activation occurs in CD4+ and CD8+ T cells during graft-versus-host disease
    Authors: Talley, S;Rademacher, DJ;Campbell, EM;
    Cell death & disease
    Species: Mouse
    Sample Types: Cell Culture Supernates
  19. The Inflammasome Pathway is Activated by Dengue Virus Non-structural Protein 1 and is Protective During Dengue Virus Infection
    Authors: Wong, MP;Juan, EYW;Chelluri, SS;Wang, P;Pahmeier, F;Castillo-Rojas, B;Blanc, SF;Biering, SB;Vance, RE;Harris, E;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Cell Culture Supernates
  20. Cefaclor causes vagus nerve-mediated depression-like symptoms with gut dysbiosis in mice
    Authors: Joo, MK;Shin, YJ;Kim, DH;
    Scientific reports
    Species: Mouse
    Sample Types: Tissue Homogenates
  21. A phylogenetic approach to explore the Aspergillus fumigatus conidial surface-associated proteome and its role in pathogenesis
    Authors: Goldman, G;Valero, C;Pinzan, C;de Castro, P;van Rhijn, N;Earle, K;Liu, H;Horta, MA;Kniemeyer, O;Kruger, T;Pschibul, A;Coemert, D;Heinekamp, T;Brakhage, A;Steenwyk, J;Mead, M;Rokas, A;Filler, S;da Rosa-Garzon, N;Delbaje, E;Bromley, M;Angeli, C;Palmisano, G;Ibrahim, A;Gago, S;Reis, TD;
    Research square
    Species: Mouse
    Sample Types: Cell Culture Supernates
  22. P2X7R influences tau aggregate burden in human tauopathies and shows distinct signalling in microglia and astrocytes
    Authors: Beltran-Lobo, P;Hughes, MM;Troakes, C;Croft, CL;Rupawala, H;Jutzi, D;Ruepp, MD;Jimenez-Sanchez, M;Perkinton, MS;Kassiou, M;Golde, TE;Hanger, DP;Verkhratsky, A;Perez-Nievas, BG;Noble, W;
    Brain, behavior, and immunity
    Species: Mouse
    Sample Types: Cell Culture Supernates
  23. 3,3-dimethyl-1-butanol and its metabolite 3,3-dimethylbutyrate ameliorate collagen-induced arthritis independent of choline trimethylamine lyase activity
    Authors: Fechtner, S;Allen, BE;Chriswell, ME;Jubair, WK;Robertson, CE;Kofonow, JN;Frank, DN;Holers, VM;Kuhn, KA;
    Research square
    Species: Mouse
    Sample Types: Cell Culture Supernates
  24. Deficient P. aeruginosa in MlaA/VacJ outer membrane lipoprotein shows decrease in rhamnolipids secretion, motility, and biofilm formation, and increase in fluoroquinolones susceptibility and innate immune response
    Authors: Kaur, M;Buyck, JM;Goormaghtigh, F;Decout, JL;Mozaheb, N;Mingeot-Leclercq, MP;
    Research in microbiology
    Species: Human
    Sample Types: Cell Culture Supernates
  25. A phylogenetic approach to explore the Aspergillus fumigatus conidial surface-associated proteome and its role in pathogenesis
    Authors: Valero, C;Pinzan, CF;de Castro, PA;van Rhijn, N;Earle, K;Liu, H;Horta, MAC;Kniemeyer, O;Krüger, T;Pschibul, A;Coemert, DN;Heinekamp, T;Brakhage, AA;Steenwyk, JL;Mead, ME;Rokas, A;Filler, SG;da Rosa-Garzon, NG;Cabral, H;Deljabe, E;Bromley, MJ;Angeli, CB;Palmisano, G;Ibrahim, AS;Gago, S;Dos Reis, TF;Goldman, GH;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Cell Culture Supernates
  26. Short-Term Caloric Restriction and Subsequent Re-Feeding Compromise Liver Health and Associated Lipid Mediator Signaling in Aged Mice
    Authors: Schädel, P;Wichmann-Costaganna, M;Czapka, A;Gebert, N;Ori, A;Werz, O;
    Nutrients
    Species: Mouse
    Sample Types: Tissue Homogenates
  27. Genetic Downregulation of the Metabotropic Glutamate Receptor Type 5 Dampens the Reactive and Neurotoxic Phenotype of Adult ALS Astrocytes
    Authors: Torazza, C;Provenzano, F;Gallia, E;Cerminara, M;Balbi, M;Bonifacino, T;Tessitore, S;Ravera, S;Usai, C;Musante, I;Puliti, A;Van Den Bosch, L;Jafar-Nejad, P;Rigo, F;Milanese, M;Bonanno, G;
    Cells
    Species: Mouse
    Sample Types: Cell Culture Supernates
  28. Caudal DMN neurons innervate the spleen and release CART peptide to regulate neuroimmune function
    Authors: Kobori, N;Moore, AN;Redell, JB;Dash, PK;
    Journal of neuroinflammation
    Species: Mouse
    Sample Types: Plasma
  29. LRRK2 G2019S promotes the development of colon cancer via modulating intestinal inflammation
    Authors: Wang, Y;Gao, JZ;Sakaguchi, T;Maretzky, T;Gurung, P;Short, S;Xiong, Y;Kang, Z;
    bioRxiv : the preprint server for biology
    Species: Mouse
    Sample Types: Cell Culture Supernates
  30. Pharmacologic inhibition of NLRP3 reduces the levels of ?-synuclein and protects dopaminergic neurons in a model of Parkinson's disease
    Authors: Amo-Aparicio, J;Daly, J;Højen, JF;Dinarello, CA;
    Journal of neuroinflammation
    Species: Mouse
    Sample Types: Tissue Homogenates
  31. Polysialylation controls immune function of myeloid cells in murine model of pneumococcal pneumonia
    Authors: Shinde, P;Kiepas, A;Zhang, L;Sudhir, S;Konstantopoulos, K;Stamatos, NM;
    Cell reports
    Species: Mouse
    Sample Types: Tissue Homogenates
  32. Poly-?-caprolactone nanocapsules loaded with copaiba essential oil reduce inflammation and pain in mice
    Authors: Pinto, EP;da Costa, SOAM;D'Haese, C;Nysten, B;Machado, FP;Rocha, LM;de Souza, TM;Beloqui, A;Machado, RR;Araújo, RS;
    International journal of pharmaceutics
    Species: Mouse
    Sample Types: Tissue Homogenates
  33. The herbicides glyphosate and glufosinate and the cyanotoxin ?-N-methylamino-l-alanine induce long-term motor disorders following postnatal exposure: the importance of prior asymptomatic maternal inflammatory sensitization
    Authors: Oummadi, A;Menuet, A;Méresse, S;Laugeray, A;Guillemin, G;Mortaud, S;
    Frontiers in neuroscience
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  34. Modified Xiaoyao San reverses lipopolysaccharide-induced depression-like behavior through suppressing microglia M1 polarization via enhancing autophagy involved in PI3K/Akt/mTOR pathway in mice
    Authors: Su, P;Wu, M;Yin, X;Li, M;Li, Y;Bai, M;Wang, B;Xu, E;
    Journal of ethnopharmacology
    Species: Mouse
    Sample Types: Tissue Homogenates
  35. Soluble epoxide hydrolase inhibitor blockage microglial cell activation in subnucleus caudalis in a persistent model of arthritis
    Authors: Tarkany Basting, R;Henrique Napimoga, M;Ant�nio Trindade Silva, C;Ballassini Abdalla, H;Campos Durso, B;Henrique Barboza Martins, L;de Abreu Cavalcanti, H;Hammock, BD;Trindade Clemente-Napimoga, J;
    International immunopharmacology
    Species: Mouse
    Sample Types: Tissue Homogenates
  36. Fisetin, an Anti-Inflammatory Agent, Overcomes Radioresistance by Activating the PERK-ATF4-CHOP Axis in Liver Cancer
    Authors: Kim, TW;
    International journal of molecular sciences
    Species: Mouse
    Sample Types: Cell Culture Supernates
  37. Candida auris uses metabolic strategies to escape and kill macrophages while avoiding robust activation of the NLRP3 inflammasome response
    Authors: Weerasinghe, H;Simm, C;Djajawi, TM;Tedja, I;Lo, TL;Simpson, DS;Shasha, D;Mizrahi, N;Olivier, FAB;Speir, M;Lawlor, KE;Ben-Ami, R;Traven, A;
    Cell reports
    Species: Mouse
    Sample Types: Cell Culture Supernates
  38. Salmonella Enteritidis T1SS protein SiiD inhibits NLRP3 inflammasome activation via repressing the mtROS-ASC dependent pathway
    Authors: Guo, Y;Gu, D;Huang, T;Li, A;Zhou, Y;Kang, X;Meng, C;Xiong, D;Song, L;Jiao, X;Pan, Z;
    PLoS pathogens
    Species: Transgenic Mouse, Mouse
    Sample Types: Cell Culture Supernates, Serum
  39. Metabololipidomic and proteomic profiling reveals aberrant macrophage activation and interrelated immunomodulatory mediator release during aging
    Authors: P Schädel, A Czapka, N Gebert, ID Jacobsen, A Ori, O Werz
    Aging Cell, 2023-04-26;0(0):e13856.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  40. Collagen-Derived Dipeptides and Amino Acids Have Immunomodulatory Effects in M1-Differentiated RAW264.7 Cells and PBMC
    Authors: T Tominaga, J Huang, S Wang, M Noguchi, Y Tong, M Asano-Orit, K Suzuki
    International Journal of Molecular Sciences, 2023-04-08;24(8):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  41. Neuroinflammation, Oxidative Stress, Apoptosis, Microgliosis and Astrogliosis in the Cerebellum of Mice Chronically Exposed to Waterpipe Smoke
    Authors: Hamadi, N;Beegam, S;Zaaba, NE;Elzaki, O;Altamimi, MA;Nemmar, A;
    Biomedicines
    Species: Mouse
    Sample Types: Tissue Homogenates
  42. ATP-releasing SWELL1 channel in spinal microglia contributes to neuropathic pain
    Authors: J Chu, J Yang, Y Zhou, J Chen, KH Chen, C Zhang, HY Cheng, N Koylass, JO Liu, Y Guan, Z Qiu
    Science Advances, 2023-03-29;9(13):eade9931.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  43. Macrophage fumarate hydratase restrains mtRNA-mediated interferon production
    Authors: A Hooftman, CG Peace, DG Ryan, EA Day, M Yang, AF McGettrick, M Yin, EN Montano, L Huo, JE Toller-Kaw, V Zecchini, TAJ Ryan, A Bolado-Car, AM Casey, HA Prag, ASH Costa, G De Los San, M Ishimori, DJ Wallace, S Venuturupa, E Nikitopoul, N Frizzell, C Johansson, A Von Kriegs, MP Murphy, C Jefferies, C Frezza, LAJ O'Neill
    Nature, 2023-03-08;615(7952):490-498.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  44. SIRT6 ameliorates LPS-induced apoptosis and tight junction injury in ARDS through the ERK1/2 pathway and autophagy
    Authors: H Liu, S Wang, L Gong, Y Shen, F Xu, Y Wang, L Hu, L Zhu
    International Journal of Medical Sciences, 2023-03-05;20(5):581-594.
    Species: Mouse
    Sample Types: BALF
  45. The DNA adenine methylase of Salmonella Enteritidis promotes their intracellular replication by inhibiting arachidonic acid metabolism pathway in macrophages
    Authors: M Wang, D Xiong, X Wang, D Gu, C Meng, X Jiao, Z Pan
    Frontiers in Microbiology, 2023-03-02;14(0):1080851.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  46. Identifying a selective inhibitor of autophagy that targets ATG12-ATG3 protein-protein interaction
    Authors: Nuta, GC;Gilad, Y;Goldberg, N;Meril, S;Bahlsen, M;Carvalho, S;Kozer, N;Barr, H;Fridmann Sirkis, Y;Herc�k, K;B?ehov�, P;Nencka, R;Bialik, S;Eisenstein, M;Kimchi, A;
    Autophagy
    Species: Mouse
    Sample Types: Cell Culture Supernates
  47. SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice
    Authors: FL Fontes-Dan, GG Fernandes, EG Gutman, EV De Lima, LS Antonio, MB Hammerle, HP Mota-Arauj, LC Colodeti, SMB Araújo, GM Froz, TN da Silva, LA Duarte, AL Salvio, KL Pires, LAA Leon, CCF Vasconcelo, L Romão, LEB Savio, JL Silva, R da Costa, JR Clarke, AT Da Poian, SV Alves-Leon, GF Passos, CP Figueiredo
    Cell Reports, 2023-02-17;42(3):112189.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  48. Small molecule inhibiting microglial nitric oxide release could become a potential treatment for neuroinflammation
    Authors: P Jordan, A Costa, E Specker, O Popp, A Volkamer, R Piske, T Obrusnik, S Kleissle, K Stuke, A Rex, M Neuenschwa, JP von Kries, M Nazare, P Mertins, H Kettenmann, SA Wolf
    PLoS ONE, 2023-02-06;18(2):e0278325.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  49. Definition of the contribution of an Osteopontin-producing CD11c+ microglial subset to Alzheimer's disease
    Authors: Y Qiu, X Shen, O Ravid, D Atrakchi, D Rand, AE Wight, HJ Kim, S Liraz-Zalt, I Cooper, M Schnaider, H Cantor
    Proceedings of the National Academy of Sciences of the United States of America, 2023-02-02;120(6):e2218915120.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  50. The NLRP3 Inflammasome Is Required for Protection Against Pseudomonas Keratitis
    Authors: A Ramadan, Z Cao, M Gadjeva, TS Zaidi, VA Rathinam, N Panjwani
    Investigative Ophthalmology & Visual Science, 2023-02-01;64(2):11.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  51. Antimicrobial overproduction sustains intestinal inflammation by inhibiting Enterococcus colonization
    Authors: KK Jang, T Heaney, M London, Y Ding, F Yeung, D Ercelen, YH Chen, J Axelrad, S Gurunathan, A Marijke Ke, ME Griffin, HC Hang, K Cadwell
    bioRxiv : the preprint server for biology, 2023-02-01;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  52. A hierarchy of cell death pathways confers layered resistance to shigellosis in mice
    Authors: JL Roncaioli, JP Babirye, RA Chavez, FL Liu, EA Turcotte, AY Lee, CF Lesser, RE Vance
    Elife, 2023-01-16;12(0):.
    Species: Mouse
    Sample Types: Fecal Supernates
  53. Phenolic and quinone methide nor-triterpenes as selective NLRP3 inflammasome inhibitors
    Authors: L González-C, J P Green, I Cuadrado, Á Amesty, S Oramas-Roy, David Brou, A Estévez-Br, S Hortelano, B de Las Her
    Bioorganic chemistry, 2023-01-14;132(0):106362.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  54. TRPC absence induces pro-inflammatory macrophages and gut microbe disorder, sensitizing mice to colitis
    Authors: Y Lin, X Cui, Q Cao, R Bi, Y Liu, D Jing, C Yue, Q Zhao, Y Wang, S Liu, Y Su, K Formoso, S Susperregu, L Birnbaumer, M Freichel, Y Yang, L You, X Gao
    International immunopharmacology, 2022-12-31;115(0):109655.
    Species: Mouse
    Sample Types: Tissue Homogenates
  55. Dysregulated systemic metabolism in a Down syndrome mouse model
    Authors: DC Sarver, C Xu, LM Velez, S Aja, AE Jaffe, MM Seldin, RH Reeves, GW Wong
    Molecular Metabolism, 2022-12-29;68(0):101666.
    Species: Mouse
    Sample Types: Serum
  56. JC2-11, a benzylideneacetophenone derivative, attenuates inflammasome activation
    Authors: G Lee, H Ahn, JH Yun, J Park, E Lee, S Oh, GS Lee
    Scientific Reports, 2022-12-28;12(1):22484.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  57. Distinct changes in endosomal composition promote NLRP3 inflammasome activation
    Authors: Z Zhang, R Venditti, L Ran, Z Liu, K Vivot, A Schürmann, JS Bonifacino, MA De Matteis, R Ricci
    Nature Immunology, 2022-11-28;0(0):.
    Species: Mouse
    Sample Types: Serum
  58. Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
    Authors: C Oh, L Li, A Verma, AD Reuven, EA Miao, JB Bliska, Y Aachoui
    Cell Reports, 2022-11-22;41(8):111688.
    Species: Mouse, Transgenic Mouse
    Sample Types: Cell Culture Supernates
  59. EC-18 prevents autoimmune arthritis by suppressing inflammatory cytokines and osteoclastogenesis
    Authors: JS Park, SC Yang, HY Jeong, SY Lee, JG Ryu, JW Choi, HY Kang, SM Kim, SH Hwang, ML Cho, SH Park
    Arthritis Research & Therapy, 2022-11-17;24(1):254.
    Species: Mouse
    Sample Types: Serum
  60. Consequences of the Lack of TNFR1 in Ouabain Response in the Hippocampus of C57BL/6J Mice
    Authors: PF Kinoshita, AM Orellana, DZ Andreotti, GA de Souza, NP de Mello, L de Sá Lima, EM Kawamoto, C Scavone
    Biomedicines, 2022-11-15;10(11):.
    Species: Mouse
    Sample Types: Serum
  61. Involvement of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor in proinflammatory mechanisms promoting cardiovascular injury mechanisms promoting cardiovascular inflammation tThe combined action of glycoinositolphospholipid from Trypanosoma cruzi and macrophage migration inhibitory factor increases proinflammatory mediator production by cardiomyocytes and vascular endothelial cells
    Authors: CS Rigazio, N Mariz-Pont, EP Caballero, FN Penas, NB Goren, MH Santamaría, RS Corral
    Microbial pathogenesis, 2022-11-12;0(0):105881.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  62. Involvement of the p38 MAPK-NLRC4-Caspase-1 Pathway in Ionizing Radiation-Enhanced Macrophage IL-1beta Production
    Authors: JS Baik, YN Seo, YC Lee, JM Yi, MH Rhee, MT Park, SD Kim
    International Journal of Molecular Sciences, 2022-11-09;23(22):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  63. Transcriptional licensing is required for Pyrin inflammasome activation in human macrophages and bypassed by mutations causing familial Mediterranean fever
    Authors: MSJ Mangan, F Gorki, K Krause, A Heinz, A Pankow, T Ebert, D Jahn, K Hiller, V Hornung, M Maurer, FI Schmidt, R Gerhard, E Latz
    PloS Biology, 2022-11-07;20(11):e3001351.
    Species: Human
    Sample Types: Cell Culture Supernates
  64. Postbiotics Prepared Using Lactobacillus paracasei CCFM1224 Prevent Nonalcoholic Fatty Liver Disease by Modulating the Gut Microbiota and Liver Metabolism
    Authors: Z Pan, B Mao, Q Zhang, X Tang, B Yang, J Zhao, S Cui, H Zhang
    International Journal of Molecular Sciences, 2022-11-04;23(21):.
    Species: Mouse
    Sample Types: Serum
  65. Only Acute but Not Chronic Thrombocytopenia Protects Mice against Left Ventricular Dysfunction after Acute Myocardial Infarction
    Authors: F Reusswig, A Polzin, M Klier, MA Dille, A Ayhan, M Benkhoff, C Lersch, A Prinz, S Gorressen, JW Fischer, M Kelm, M Elvers
    Cells, 2022-11-04;11(21):.
    Species: Mouse
    Sample Types: Plasma
  66. PD-1/PD-L1 inhibition enhances chemotherapy-induced neuropathic pain by suppressing neuroimmune antinociceptive signaling
    Authors: CWS Wanderley, A Maganin, B Adjafre, AS Mendes, CE Anibal Sil, AU Quadros, JPM Luiz, CMS Silva, NR Silva, FF Oliveira, FIF Gomes, JLJ Restrepo, CA Speck-Hern, F Turaça, GVL Silva, GR Pigatto, HI Nakaya, JM Mota, R Barroso-So, JC Alves-Filh, TM Cunha, FQ Cunha
    Cancer Immunology Research, 2022-11-02;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  67. Blockage of KHSRP-NLRP3 by MCC950 Can Reverse the Effect of Manganese-Induced Neuroinflammation in N2a Cells and Rat Brain
    Authors: S Singh, IA Shaikh, SS More, MH Mahnashi, HM Almohaimee, M El-Sherbin, MM Ghoneim, A Umar, HK Soni, H Agrawal, BA Mannasaheb, AA Khan, UM Muddapur, SMS Iqubal
    International Journal of Molecular Sciences, 2022-10-30;23(21):.
    Species: Mouse, Rat
    Sample Types: Cell Culture Supernates, Tissue Homogenates
  68. Gasdermin D restricts anti-tumor immunity during PD-L1 checkpoint blockade
    Authors: Y Jiang, Y Yang, Y Hu, R Yang, J Huang, Y Liu, Y Wu, S Li, C Ma, F Humphries, B Wang, X Wang, Z Hu, S Yang
    Cell Reports, 2022-10-25;41(4):111553.
    Species: Mouse
    Sample Types: Tissue Homogenates
  69. Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice
    Authors: S Li, Y Fang, Y Zhang, M Song, X Zhang, X Ding, H Yao, M Chen, Y Sun, J Ding, Q Wang, M Lu, G Wu, G Hu
    Cell Reports, 2022-10-25;41(4):111532.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  70. Combinatorial microRNA Loading into Extracellular Vesicles for Increased Anti-Inflammatory Efficacy
    Authors: AE Pottash, D Levy, A Jeyaram, L Kuo, SM Kronstadt, W Chao, SM Jay
    Non-coding RNA, 2022-10-21;8(5):.
    Species: Mouse
    Sample Types: Plasma
  71. YAP1 protects against septic liver injury via ferroptosis resistance
    Authors: J Wang, Q Zhu, R Li, J Zhang, X Ye, X Li
    Cell & bioscience, 2022-10-01;12(1):163.
    Species: Mouse
    Sample Types: Tissue Homogenates
  72. Homoharringtonine Attenuates Dextran Sulfate Sodium-Induced Colitis by Inhibiting NF-kappaB Signaling
    Authors: J Liu, L Shi, W Huang, Z Zheng, X Huang, Y Su
    Mediators of Inflammation, 2022-09-29;2022(0):3441357.
    Species: Mouse
    Sample Types: Cell Lysates
  73. In vivo peptide-based delivery of a gene-modifying enzyme into cells of the central nervous system
    Authors: JK Allen, TC Sutherland, AR Prater, CG Geoffroy, JP Pellois
    Science Advances, 2022-09-28;8(39):eabo2954.
    Species: Mouse
    Sample Types: Tissue Homogenates
  74. The escape of Candida albicans from macrophages is enabled by the fungal toxin candidalysin and two host cell death pathways
    Authors: FAB Olivier, V Hilsenstei, H Weerasingh, A Weir, S Hughes, S Crawford, JE Vince, MJ Hickey, A Traven
    Cell Reports, 2022-09-20;40(12):111374.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  75. Bone marrow adipocytes drive the development of tissue invasive Ly6Chigh monocytes during obesity
    Authors: P Boroumand, DC Prescott, T Mukherjee, PJ Bilan, M Wong, J Shen, I Tattoli, Y Zhou, A Li, T Sivasubram, N Shi, LY Zhu, Z Liu, C Robbins, DJ Philpott, SE Girardin, A Klip
    Elife, 2022-09-20;11(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  76. FAAH served a key membrane-anchoring and stabilizing role for NLRP3 protein independently of the endocannabinoid system
    Authors: Y Zhu, H Zhang, H Mao, S Zhong, Y Huang, S Chen, K Yan, Z Zhao, X Hao, Y Zhang, H Yao, X Huang, M Wang, W Zhang, J Li, G Meng, X Qin, Z Ye, J Shen, Y Song, Y Xu, Z Yang, L Wang, Y Zhang, L Wen
    Cell Death and Differentiation, 2022-09-14;0(0):.
    Species: Mouse
    Sample Types: Serum
  77. Context-dependent function of TSLP and IL-1beta in skin allergic sensitization and atopic march
    Authors: J Segaud, W Yao, P Marschall, F Daubeuf, C Lehalle, B German, P Meyer, P Hener, C Hugel, E Flatter, M Guivarch, L Clauss, SF Martin, M Oulad-Abde, M Li
    Nature Communications, 2022-09-01;13(1):4703.
    Species: Mouse
    Sample Types: Tissue Homogenates
  78. Dynamics of action of a Lys-49 and an Asp-49 PLA2s on inflammasome NLRP3 activation in murine macrophages
    Authors: CN Boeno, MV Paloschi, JA Lopes, MD Souza Silv, JR Evangelist, VP Dos Reis, S da S Setúb, AM Soares, JP Zuliani
    International immunopharmacology, 2022-08-27;112(0):109194.
    Species: Mouse
    Sample Types: Cell Supernates
  79. Extracellular matrix of early pulmonary fibrosis modifies the polarization of alveolar macrophage
    Authors: Y Zhang, L Zhu, J Hong, C Chen
    International immunopharmacology, 2022-08-24;111(0):109179.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  80. Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation
    Authors: Y Ni, GH Wu, JJ Cai, R Zhang, Y Zheng, JQ Liu, XH Yang, X Yang, Y Shen, JM Lai, XM Ye, SJ Mo
    International journal of biological sciences, 2022-08-08;18(13):5168-5184.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  81. Concerted regulation of OPG/RANKL/ NF?kappaB/MMP-13 trajectories contribute to ameliorative capability of prodigiosin and/or low dose gamma-radiation against adjuvant- induced arthritis in rats
    Authors: MK Abdel-Rafe, NM Thabet, MM Amin
    International immunopharmacology, 2022-08-06;111(0):109068.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  82. The role of PP2A /NLRP3 signaling pathway in ambient particulate matter 2.5 induced lung injury
    Authors: B Han, Q Liu, X Su, L Zhou, B Zhang, H Kang, J Ning, C Li, B Zhao, Y Niu, W Chen, L Chen, R Zhang
    Chemosphere, 2022-08-01;307(0):135794.
    Species: Mouse
    Sample Types: BALF
  83. HIF-1alpha induces glycolytic reprograming in tissue-resident alveolar macrophages to promote cell survival during acute lung injury
    Authors: PS Woods, LM Kimmig, KA Sun, AY Meliton, OR Shamaa, Y Tian, R Cetin-Atal, WW Sharp, RB Hamanaka, GM Mutlu
    Elife, 2022-07-13;11(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  84. Lithocholic acid inhibits dendritic cell activation by reducing intracellular glutathione via TGR5 signaling
    Authors: J Hu, Y Zhang, S Yi, C Wang, X Huang, S Pan, J Yang, G Yuan, S Tan, H Li
    International journal of biological sciences, 2022-07-11;18(11):4545-4559.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  85. Allergen protease-activated stress granule assembly and gasdermin D fragmentation control interleukin-33 secretion
    Authors: W Chen, S Chen, C Yan, Y Zhang, R Zhang, M Chen, S Zhong, W Fan, S Zhu, D Zhang, X Lu, J Zhang, Y Huang, L Zhu, X Li, D Lv, Y Fu, H Iv, Z Ling, L Ma, H Jiang, G Long, J Zhu, D Wu, B Wu, B Sun
    Nature Immunology, 2022-07-06;23(7):1021-1030.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  86. Artemisinin inhibits neutrophil and macrophage chemotaxis, cytokine production and NET release
    Authors: HOJ Morad, S Luqman, LG Pinto, KP Cunningham, B Vilar, G Clayton, M Shankar-Ha, PA McNaughton
    Scientific Reports, 2022-06-30;12(1):11078.
    Species: Mouse
    Sample Types: BALF
  87. Synthetic cannabinoids reduce the inflammatory activity of microglia and subsequently improve neuronal survival in vitro
    Authors: AP Young, EM Denovan-Wr
    Brain, Behavior, and Immunity, 2022-06-25;105(0):29-43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  88. Phosphatidylinositol 3-Kinase (PI3K) Orchestrates Aspergillus fumigatus-Induced Eosinophil Activation Independently of Canonical Toll-Like Receptor (TLR)/C-Type-Lectin Receptor (CLR) Signaling
    Authors: A Dietschman, S Schruefer, S Westermann, F Henkel, K Castiglion, R Willebrand, J Adam, J Ruland, R Lang, DC Sheppard, J Esser-von-, D Radtke, S Krappmann, D Voehringer
    MBio, 2022-06-13;0(0):e0123922.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  89. Neuroprotective effects of ex vivo-expanded regulatory T cells on trimethyltin-induced neurodegeneration in mice
    Authors: SY Park, H Yang, M Ye, X Liu, I Shim, YT Chang, H Bae
    Journal of Neuroinflammation, 2022-06-11;19(1):143.
    Species: Mouse
    Sample Types: Serum
  90. Acinetobacter quorum sensing contributes to inflammation-induced inhibition of orthopaedic implant osseointegration
    Authors: H Choe, BS Hausman, KM Hujer, O Akkus, PN Rather, Z Lee, RA Bonomo, EM Greenfield
    Oncogene, 2022-06-09;43(0):267-276.
    Species: Mouse
    Sample Types: Tissue Homogenates
  91. ZBP1 promotes inflammatory responses downstream of TLR3/TLR4 via timely delivery of RIPK1 to TRIF
    Authors: HI Muendlein, WM Connolly, Z Magri, D Jetton, I Smirnova, A Degterev, S Balachandr, A Poltorak
    Proceedings of the National Academy of Sciences of the United States of America, 2022-06-06;119(24):e2113872119.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  92. Asymmetric synthesis of flavanols via Cu-catalyzed kinetic resolution of chromenes and their anti-inflammatory activity
    Authors: Q Yang, Z Wang, CHH Hor, H Xiao, Z Bian, JJ Wang
    Science Advances, 2022-06-03;8(22):eabm9603.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  93. Macrophage-intrinsic DUOX1 contributes to type 2 inflammation and mucus metaplasia during allergic airway disease
    Authors: CR Morris, A Habibovic, CM Dustin, C Schiffers, MC Lin, JL Ather, YMW Janssen-He, ME Poynter, O Utermohlen, M Krönke, A van der Vl
    Mucosal Immunology, 2022-06-02;0(0):.
    Species: Mouse
    Sample Types: BALF
  94. The Therapeutic Treatment with the GAG-Binding Chemokine Fragment CXCL9(74-103) Attenuates Neutrophilic Inflammation and Lung Dysfunction during Klebsiella pneumoniae Infection in Mice
    Authors: D Boff, RC Russo, H Crijns, VLS de Oliveir, MS Mattos, PE Marques, GB Menezes, AT Vieira, MM Teixeira, P Proost, FA Amaral
    International Journal of Molecular Sciences, 2022-06-02;23(11):.
    Species: Mouse
    Sample Types: BALF
  95. NLRP3 Inflammasome Negatively Regulates RANKL-Induced Osteoclastogenesis of Mouse Bone Marrow Macrophages but Positively Regulates It in the Presence of Lipopolysaccharides
    Authors: MI Alam, M Mae, F Farhana, M Oohira, Y Yamashita, Y Ozaki, E Sakai, A Yoshimura
    Oncogene, 2022-05-29;23(11):.
    Species: Mouse
    Sample Types: Cell Lysates
  96. The antioxidant enzyme Peroxiredoxin-1 controls stroke-associated microglia against acute ischemic stroke
    Authors: S Kim, W Lee, H Jo, SK Sonn, SJ Jeong, S Seo, J Suh, J Jin, HY Kweon, TK Kim, SH Moon, S Jeon, JW Kim, YR Kim, EW Lee, HK Shin, SH Park, GT Oh
    Redox Biology, 2022-05-25;54(0):102347.
    Species: Mouse
    Sample Types: Serum
  97. Preclinical Efficacy of a Capsid Virus-like Particle-Based Vaccine Targeting IL-1beta for Treatment of Allergic Contact Dermatitis
    Authors: L Goksøyr, AB Funch, AK Okholm, TG Theander, WA de Jongh, CM Bonefeld, AF Sander
    Vaccines, 2022-05-23;10(5):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  98. Development of sulfonamide-based NLRP3 inhibitors: Further modifications and optimization through structure-activity relationship studies
    Authors: Y Xu, Y Xu, H Blevins, C Guo, S Biby, XY Wang, C Wang, S Zhang
    European Journal of Medicinal Chemistry, 2022-05-21;238(0):114468.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  99. Mitochondrial electron transport chain is necessary for NLRP3 inflammasome activation
    Authors: LK Billingham, JS Stoolman, K Vasan, AE Rodriguez, TA Poor, M Szibor, HT Jacobs, CR Reczek, A Rashidi, P Zhang, J Miska, NS Chandel
    Nature Immunology, 2022-04-28;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  100. Salmonella Enteritidis GalE Protein Inhibits LPS-Induced NLRP3 Inflammasome Activation
    Authors: T Huang, D Gu, Y Guo, A Li, X Kang, X Jiao, Z Pan
    Microorganisms, 2022-04-26;10(5):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  101. Bladder epithelial cell phosphate transporter inhibition protects mice against uropathogenic Escherichia coli infection
    Authors: Y Pang, Z Cheng, S Zhang, S Li, X Li, X Li, X Zhang, X Li, Y Feng, H Cui, Z Chen, L Liu, Q Li, J Huang, M Zhang, S Zhu, L Wang, L Feng
    Cell Reports, 2022-04-19;39(3):110698.
    Species: Mouse
    Sample Types: Serum
  102. ADP-ribosylating adjuvant reveals plasticity in cDC1 cells that drive mucosal Th17 cell development and protection against influenza virus infection
    Authors: M Arabpour, C Lebrero-Fe, K Schön, A Strömberg, V Börjesson, K Lahl, M Ballegeer, X Saelens, D Angeletti, W Agace, N Lycke
    Mucosal Immunology, 2022-04-13;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  103. Liposomal Dexamethasone Reduces A/H1N1 Influenza-Associated Morbidity in Mice
    Authors: JW Kwon, H Quan, J Song, H Chung, D Jung, JJ Hong, YR Na, SH Seok
    Frontiers in Microbiology, 2022-04-12;13(0):845795.
    Species: Mouse
    Sample Types: BALF
  104. Effects of mango and mint pod-based e-cigarette aerosol inhalation on inflammatory states of the brain, lung, heart, and colon in mice
    Authors: A Moshensky, CS Brand, H Alhaddad, J Shin, JA Masso-Silv, I Advani, D Gunge, A Sharma, S Mehta, A Jahan, S Nilaad, J Olay, W Gu, T Simonson, D Almarghala, J Pham, S Perera, K Park, R Al-Kolla, H Moon, S Das, M Byun, Z Shah, Y Sari, J Heller Bro, LE Crotty Ale
    Elife, 2022-04-12;11(0):.
    Species: Mouse
    Sample Types: BALF
  105. Menthone Inhalation Alleviates Local and Systemic Allergic Inflammation in Ovalbumin-Sensitized and Challenged Asthmatic Mice
    Authors: YH Su, JY Lin
    International Journal of Molecular Sciences, 2022-04-04;23(7):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  106. The Mechanism of Pertussis Cough Revealed by the Mouse-Coughing Model
    Authors: Y Hiramatsu, K Suzuki, T Nishida, N Onoda, T Satoh, S Akira, M Ikawa, H Ikeda, J Kamei, S Derouiche, M Tominaga, Y Horiguchi
    MBio, 2022-03-31;0(0):e0319721.
    Species: Mouse
    Sample Types: Cell culture supernate
  107. Disulfiram inhibits neutrophil extracellular trap formation protecting rodents from acute lung injury and SARS-CoV-2 infection
    Authors: JM Adrover, L Carrau, J Da beta ler-Ple, Y Bram, V Chandar, S Houghton, D Redmond, JR Merrill, M Shevik, BR tenOever, SK Lyons, RE Schwartz, M Egeblad
    JCI Insight, 2022-03-08;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  108. Nociceptor-derived Reg3gamma prevents endotoxic death by targeting kynurenine pathway in microglia
    Authors: E Sugisawa, T Kondo, Y Kumagai, H Kato, Y Takayama, K Isohashi, E Shimosegaw, N Takemura, Y Hayashi, T Sasaki, MM Martino, M Tominaga, K Maruyama
    Cell Reports, 2022-03-08;38(10):110462.
    Species: Mouse
    Sample Types: Plasma
  109. Acute exposure to phthalates during recovery from a myocardial infarction induces greater inflammasome activation in male C57bl/6N mice
    Authors: A Schwendt, JB Chammas, LE Chalifour
    Toxicology and Applied Pharmacology, 2022-03-01;440(0):115954.
    Species: Mouse
    Sample Types: Plasma
  110. The phosphoinositide-3-kinase (PI3K)-delta inhibitor seletalisib impairs monocyte-derived dendritic cells maturation, APC function, and promotes their migration to CCR7 and CXCR4 ligands
    Authors: F Scopelliti, L Mercurio, C Cattani, V Dimartino, C Albanesi, G Costanzo, C Mirisola, S Madonna, A Cavani
    Journal of leukocyte biology, 2022-02-24;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  111. Fibrotic lung disease inhibits innate immune responses to Staphylococcal pneumonia via impaired neutrophil and macrophage function
    Authors: HI Warheit-Ni, SJ Edwards, S SenGupta, CA Parent, X Zhou, DN O'Dwyer, BB Moore
    JCI Insight, 2022-02-22;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  112. Inhibition of mitoNEET attenuates LPS-induced inflammation and oxidative stress
    Authors: S Lee, BG Seok, SJ Lee, SW Chung
    Cell Death & Disease, 2022-02-08;13(2):127.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  113. Recombinant BCG Expressing the Subunit 1 of Pertussis Toxin Induces Innate Immune Memory and Confers Protection against Non-Related Pathogens
    Authors: AI Kanno, D Boraschi, LCC Leite, D Rodriguez
    Vaccines, 2022-02-03;10(2):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  114. Recruitment and activation of type 3 innate lymphoid cells promote antitumor immune responses
    Authors: M Bruchard, M Geindreau, A Perrichet, C Truntzer, E Ballot, R Boidot, C Racoeur, E Barsac, F Chalmin, C Hibos, T Baranek, C Paget, B Ryffel, C Rébé, C Paul, F Végran, F Ghiringhel
    Nature Immunology, 2022-01-31;23(2):262-274.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  115. Langerhans cells and cDC1s play redundant roles in mRNA-LNP induced protective anti-influenza and anti-SARS-CoV-2 immune responses
    Authors: S Ndeupen, A Bouteau, C Herbst, Z Qin, S Jacobsen, NE Powers, Z Hutchins, D Kurup, LZ Diba, M Watson, H Ramage, BZ Igyártó
    PloS Pathogens, 2022-01-24;18(1):e1010255.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  116. Clinical-like cryotherapy in acute knee arthritis of the knee improves inflammation signs, pain, joint swelling, and motor performance in mice
    Authors: PATS Castro, GM Barbosa, DH Machanocke, RS Peres, TM Cunha, JE Cunha, FFB Oliveira, FS Ramalho, TL Russo, FQ Cunha, TF Salvini
    PLoS ONE, 2022-01-21;17(1):e0261667.
    Species: Mouse
    Sample Types: Tissue Homogenates
  117. The Compound (E)-2-Cyano-N,3-diphenylacrylamide (JMPR-01): A Potential Drug for Treatment of Inflammatory Diseases
    Authors: PR da Silva, RF do Espírit, CO Melo, FE Pachú Cava, TB Costa, YV Barbosa, YMSM E Silva, NF de Sousa, CF Villarreal, RO de Moura, VL Dos Santos
    Pharmaceutics, 2022-01-13;14(1):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  118. Intense Acute Swimming Induces Delayed-Onset Muscle Soreness Dependent on Spinal Cord Neuroinflammation
    Authors: SM Borghi, SKD Bussulo, FA Pinho-Ribe, V Fattori, TT Carvalho, FS Rasquel-Ol, TH Zaninelli, CR Ferraz, AMB Casella, FQ Cunha, TM Cunha, R Casagrande, WA Verri
    Frontiers in Pharmacology, 2022-01-07;12(0):734091.
    Species: Mouse
    Sample Types: Tissue Homogenates
  119. The Salutary Effects of Catalpol on Diesel Exhaust Particles-Induced Thrombogenic Changes and Cardiac Oxidative Stress, Inflammation and Apoptosis
    Authors: A Nemmar, S Beegam, NE Zaaba, S Alblooshi, S Alseiari, BH Ali
    Biomedicines, 2022-01-04;10(1):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  120. Ephedrine ameliorates chronic obstructive pulmonary disease (COPD) through restraining endoplasmic reticulum (ER) stress in vitro and in vivo
    Authors: HL Wang, FQ Chen, LJ Wu
    International immunopharmacology, 2021-12-22;103(0):107842.
    Species: Mouse
    Sample Types: BALF
  121. Metabolic Regulation of Macrophages by SIRT1 Determines Activation During Cholestatic Liver Disease in Mice
    Authors: A Isaacs-Ten, M Moreno-Gon, C Bone, A Martens, F Bernuzzi, T Ludwig, C Hellmich, K Hiller, SA Rushworth, N Beraza
    Cellular and Molecular Gastroenterology and Hepatology, 2021-12-22;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
  122. IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-gamma production by CD25+Foxp3- T cells
    Authors: J Tomala, P Weberova, B Tomalova, Z Jiraskova, L Sivak, J Kovarova, M Kovar
    Elife, 2021-12-21;10(0):.
    Species: Mouse
    Sample Types: Serum
  123. Differences in Cell-Intrinsic Inflammatory Programs of Yolk Sac and Bone Marrow Macrophages
    Authors: S Elhag, C Stremmel, A Zehrer, J Plocke, R Hennel, M Keuper, C Knabe, J Winterhalt, V Gölling, L Tomas, T Weinberger, M Fischer, L Liu, F Wagner, M Lorenz, K Stark, H Häcker, M Schmidt-Su, U Völker, M Jastroch, K Lauber, T Straub, B Walzog, E Hammer, C Schulz
    Cells, 2021-12-17;10(12):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  124. Heterocellular OSM-OSMR signalling reprograms fibroblasts to promote pancreatic cancer growth and metastasis
    Authors: BY Lee, EKJ Hogg, CR Below, A Kononov, A Blanco-Gom, F Heider, J Xu, C Hutton, X Zhang, T Scheidt, K Beattie, A Lamarca, M McNamara, JW Valle, C Jørgensen
    Nature Communications, 2021-12-17;12(1):7336.
    Species: Mouse
    Sample Types: Tissue Homogenates
  125. Identification of an ASC oligomerization inhibitor for the treatment of inflammatory diseases
    Authors: PM Soriano-Te, G García-Laí, M Marco-Salv, J Pardo, M Arias, C DeFord, I Merfort, MJ Vicent, P Pelegrín, M Sancho, M Orzáez
    Cell Death & Disease, 2021-12-13;12(12):1155.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  126. Hepatocytes are resistant to cell death from canonical and non-canonical inflammasome-activated pyroptosis
    Authors: P Sun, J Zhong, H Liao, P Loughran, J Mulla, G Fu, D Tang, J Fan, TR Billiar, W Gao, MJ Scott
    Cellular and Molecular Gastroenterology and Hepatology, 2021-12-07;0(0):.
    Species: Mouse
    Sample Types: Plasma
  127. The Role of Cytokines Produced via the NLRP3 Inflammasome in Mouse Macrophages Stimulated with Dental Calculus in Osteoclastogenesis
    Authors: M Mae, MI Alam, Y Yamashita, Y Ozaki, K Higuchi, SM Ziauddin, JL Montenegro, E Sakai, T Tsukuba, A Yoshimura
    International Journal of Molecular Sciences, 2021-11-18;22(22):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  128. The APPL1-Rab5 axis restricts NLRP3 inflammasome activation through early endosomal-dependent mitophagy in macrophages
    Authors: KKL Wu, K Long, H Lin, PMF Siu, RLC Hoo, D Ye, A Xu, KKY Cheng
    Nature Communications, 2021-11-17;12(1):6637.
    Species: Mouse
    Sample Types: Tissue Homogenates
  129. Anti-IAPP Monoclonal Antibody Improves Clinical Symptoms in a Mouse Model of Type 2 Diabetes
    Authors: AS Vogt, ES Roesti, MO Mohsen, A Leonchiks, M Vogel, MF Bachmann
    Vaccines, 2021-11-12;9(11):.
    Species: Mouse
    Sample Types: Serum
  130. Cooling and Sterile Inflammation in an Oxygen-Glucose-Deprivation/Reperfusion Injury Model in BV-2 Microglia
    Authors: J Lücht, N Rolfs, SJ Wowro, F Berger, KRL Schmitt, G Tong
    Mediators of Inflammation, 2021-11-05;2021(0):8906561.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  131. Endangered Lymphocytes: The Effects of Alloxan and Streptozotocin on Immune Cells in Type 1 Induced Diabetes
    Authors: LAD Queiroz, JB Assis, JPT Guimarães, ESA Sousa, AC Milhomem, KKS Sunahara, A Sá-Nunes, JO Martins
    Mediators of Inflammation, 2021-10-19;2021(0):9940009.
    Species: Mouse
    Sample Types: Tissue Homogenates
  132. Sulforaphane ameliorates non-alcoholic fatty liver disease in mice by promoting FGF21/FGFR1 signaling pathway
    Authors: YK Wu, ZN Ren, SL Zhu, YZ Wu, G Wang, H Zhang, W Chen, Z He, XL Ye, QX Zhai
    Acta pharmacologica Sinica, 2021-10-15;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  133. Sambucus nigra: A traditional medicine effective in reducing inflammation in mice
    Authors: JR Santin, L Benvenutti, MF Broering, R Nunes, FC Goldoni, YBK Patel, JA de Souza, MAT Kopp, P de Souza, RCV da Silva, MVD Pastor, AB de Souza, LD Testoni, AG Couto, TMB Bresolin, NLM Quintão
    Journal of ethnopharmacology, 2021-10-11;283(0):114736.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  134. Oxidized carbon black nanoparticles induce endothelial damage through C-X-C chemokine receptor 3-mediated pathway
    Authors: N Majumder, M Velayutham, D Bitounis, VK Kodali, MH Hasan Mazu, J Amedro, VV Khramtsov, A Erdely, T Nurkiewicz, P Demokritou, EE Kelley, S Hussain
    Redox Biology, 2021-10-04;47(0):102161.
    Species: Mouse
    Sample Types: BALF
  135. Parabens disrupt non-canonical inflammasome activation
    Authors: H Ahn, H Lee, G Lee, J Park, HW Sung, E Lee, GS Lee
    International immunopharmacology, 2021-09-30;101(0):108196.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  136. Anti-inflammatory activity of lefamulin versus azithromycin and dexamethasone in vivo and in vitro in a lipopolysaccharide-induced lung neutrophilia mouse model
    Authors: M Hafner, S Paukner, WW Wicha, B Hrva?i?, M Cedilak, I Faraho, SP Gelone
    PLoS ONE, 2021-09-29;16(9):e0237659.
    Species: Mouse
    Sample Types: Tissue Homogenates
  137. Gut microbiota-mediated secondary bile acids regulate dendritic cells to attenuate autoimmune uveitis through TGR5 signaling
    Authors: J Hu, C Wang, X Huang, S Yi, S Pan, Y Zhang, G Yuan, Q Cao, X Ye, H Li
    Cell Reports, 2021-09-21;36(12):109726.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  138. Proteopathic tau primes and activates interleukin-1beta via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
    Authors: S Jiang, NM Maphis, J Binder, D Chisholm, L Weston, W Duran, C Peterson, A Zimmerman, MA Mandell, SD Jett, E Bigio, C Geula, N Mellios, JP Weick, GA Rosenberg, E Latz, MT Heneka, K Bhaskar
    Cell Reports, 2021-09-21;36(12):109720.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  139. Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2
    Authors: WJ Melvin, CO Audu, FM Davis, SB Sharma, A Joshi, A DenDekker, S Wolf, E Barrett, K Mangum, X Zhou, M Bame, A Ruan, A Obi, SL Kunkel, BB Moore, KA Gallagher
    Proceedings of the National Academy of Sciences of the United States of America, 2021-09-21;118(38):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  140. The SNX-482 peptide from Hysterocrates gigas spider acts as an immunomodulatory molecule activating macrophages
    Authors: J Munhoz, R Thomé, A Rostami, LLW Ishikawa, L Verinaud, C Rapôso
    Peptides, 2021-09-16;146(0):170648.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  141. Peony seed oil ameliorates neuroinflammation-mediated cognitive deficits by suppressing microglial activation through inhibition of NF-kappaB pathway in presenilin 1/2 conditional double knockout mice
    Authors: J Gao, L Wang, C Zhao, Y Wu, Z Lu, Y Gu, Z Ba, X Wang, J Wang, Y Xu
    Journal of leukocyte biology, 2021-09-08;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  142. Oxidant-induced epithelial alarmin pathway mediates lung inflammation and functional decline following ultrafine carbon and ozone inhalation co-exposure
    Authors: N Majumder, WT Goldsmith, VK Kodali, M Velayutham, SA Friend, VV Khramtsov, TR Nurkiewicz, A Erdely, PC Zeidler-Er, V Castranova, JR Harkema, EE Kelley, S Hussain
    Redox Biology, 2021-08-05;46(0):102092.
    Species: Mouse
    Sample Types: BALF
  143. Correction: Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol
    Authors: MG Dorrington, CJ Bradfield, JB Lack, B Lin, SP John, JJ Liang, T Starr, O Ernst, JL Gross, J Sun, AH Miller, O Steele-Mor, IDC Fraser
    PloS Pathogens, 2021-08-04;17(8):e1009821.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  144. Pertactin contributes to shedding and transmission of Bordetella bronchiseptica
    Authors: L Ma, KK Dewan, DL Taylor-Mul, SM Wagner, B Linz, I Rivera, Y Su, AD Caulfield, U Blas-Macha, ET Harvill
    PloS Pathogens, 2021-08-04;17(8):e1009735.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  145. A phenotypic high-content, high-throughput screen identifies inhibitors of NLRP3 inflammasome activation
    Authors: S Nizami, V Millar, K Arunasalam, T Zarganes-T, D Brough, G Tresadern, PE Brennan, JB Davis, D Ebner, E Di Daniel
    Scientific Reports, 2021-07-28;11(1):15319.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  146. Peroxiredoxin AhpC1 protects Pseudomonas aeruginosa against the inflammatory oxidative burst and confers virulence
    Authors: LS Rocha, BPD Silva, TML Correia, RPD Silva, DA Meireles, R Pereira, LES Netto, FC Meotti, RF Queiroz
    Redox Biology, 2021-07-19;46(0):102075.
    Species: Mouse
    Sample Types: Serum
  147. Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs
    Authors: L Benvenutti, R Nunes, I Venturi, SA Ramos, MF Broering, FC Goldoni, SE Pavan, MVD Pastor, A Malheiros, NLM Quintão, ES Fernandes, JR Santin
    Journal of Immunology Research, 2021-07-19;2021(0):9957451.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  148. Acute Lung Injury in Cholinergic-Deficient Mice Supports Anti-Inflammatory Role of alpha7 Nicotinic Acetylcholine Receptor
    Authors: NM Pinheiro, R Banzato, I Tibério, MAM Prado, VF Prado, AK Hamouda, CM Prado
    International Journal of Molecular Sciences, 2021-07-14;22(14):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  149. PB1-F2 amyloid-like fibers correlate with pro-inflammatory signaling and respiratory distress in influenza-infected mice
    Authors: C Chevalier, O Leymarie, L Sedano, B Da Costa, CA Richard, P Maisonnass, M Réfregiers, F Jamme, R Le Goffic
    The Journal of Biological Chemistry, 2021-06-17;0(0):100885.
    Species: Mouse
    Sample Types: BALF
  150. The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity
    Authors: C Xu, S Sun, T Johnson, R Qi, S Zhang, J Zhang, K Yang
    Cell Reports, 2021-06-15;35(11):109235.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  151. Anti-inflammatory Effects of Empagliflozin and Gemigliptin on LPS-Stimulated Macrophage via the IKK/NF-&kappaB, MKK7/JNK, and JAK2/STAT1 Signalling Pathways
    Authors: N Lee, YJ Heo, SE Choi, JY Jeon, SJ Han, DJ Kim, Y Kang, KW Lee, HJ Kim
    Journal of Immunology Research, 2021-06-02;2021(0):9944880.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  152. Clostridioides difficile spores stimulate inflammatory cytokine responses and induce cytotoxicity in macrophages
    Authors: PJ Chiu, J Rathod, YP Hong, PJ Tsai, YP Hung, WC Ko, JW Chen, D Paredes-Sa, IH Huang
    Anaerobe, 2021-05-31;70(0):102381.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  153. Probiotic and Functional Properties of Limosilactobacillus reuteri INIA P572
    Authors: P Diez-Echav, I Martín-Cab, J Garrido-Me, S Langa, T Vezza, JM Landete, L Hidalgo-Ga, F Algieri, MJ Mayer, A Narbad, A García-Laf, M Medina, A Rodríguez-, ME Rodríguez-, J Gálvez, JL Arqués
    Nutrients, 2021-05-29;13(6):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  154. d-enantiomers of CATH-2 enhance the response of macrophages against Streptococcus suis serotype 2
    Authors: RM van Harten, JLM Tjeerdsma-, A de Greeff, MD Balhuizen, A van Dijk, EJA Veldhuizen, HP Haagsman, MR Scheenstra
    Journal of advanced research, 2021-05-26;36(0):101-112.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  155. Serum Amyloid A1/Toll-Like Receptor-4 Axis, an Important Link between Inflammation and Outcome of TBI Patients
    Authors: V Farré-Alin, A Palomino-A, P Narros-Fer, AB Lopez-Rodr, C Decouty-Pe, A Muñoz-Mont, J Zamorano-F, B Mansilla-F, J Giner-Garc, P García-Fei, M Sáez-Alegr, AJ Palpán-Flo, JM Roda-Frade, CS Carabias, JM Rosa, B Civantos-M, S Yus-Teruel, L Gandía, A Lagares, BJ Hernández-, J Egea
    Biomedicines, 2021-05-25;9(6):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  156. NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes
    Authors: FRC Costa, JA Leite, DM Rassi, JF da Silva, J Elias-Oliv, JB Guimarães, MC Foss-Freit, NOS Câmara, A Pontillo, RC Tostes, JS Silva, D Carlos
    Cell Reports, 2021-05-25;35(8):109176.
    Species: Mouse
    Sample Types: Tissue Homogenates
  157. &beta-Glucan-stimulated neutrophil secretion of IL-1&alpha is independent of GSDMD and mediated through extracellular vesicles
    Authors: B Ratitong, M Marshall, E Pearlman
    Cell Reports, 2021-05-18;35(7):109139.
    Species: Mouse, Transgenic Mouse
    Sample Types: Cell Culture Supernates
  158. Studies of involvement of G-protein coupled receptor-3 in cannabidiol effects on inflammatory responses of mouse primary astrocytes and microglia
    Authors: J Wu, N Chen, Y Liu, G Godlewski, HJ Kaplan, SH Shrader, ZH Song, H Shao
    PLoS ONE, 2021-05-13;16(5):e0251677.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  159. Topical administration of the kappa opioid receptor agonist nalfurafine suppresses corneal neovascularization and inflammation
    Authors: H Shokirova, T Inomata, T Saitoh, J Zhu, K Fujio, Y Okumura, A Yanagawa, K Fujimoto, J Sung, A Eguchi, M Miura, K Nagino, K Hirosawa, M Kuwahara, Y Akasaki, H Nagase, A Murakami
    Scientific Reports, 2021-04-21;11(1):8647.
    Species: Mouse
    Sample Types: Tissue Homogenates
  160. 4R-cembranoid confers neuroprotection against LPS-induced hippocampal inflammation in mice
    Authors: LA Rojas-Coló, PK Dash, FA Morales-Ví, M Lebrón-Dáv, PA Ferchmin, JB Redell, G Maldonado-, WI Vélez-Torr
    Journal of Neuroinflammation, 2021-04-19;18(1):95.
    Species: Mouse
    Sample Types: Plasma
  161. Thymoquinone, a Dietary Bioactive Compound, Exerts Anti-Inflammatory Effects in Colitis by Stimulating Expression of the Colonic Epithelial PPAR-&gamma Transcription Factor
    Authors: B Venkataram, S Almarzooqi, V Raj, AT Alhassani, AS Alhassani, KJ Ahmed, VS Subramania, SK Ojha, S Attoub, TE Adrian, SB Subramanya
    Nutrients, 2021-04-17;13(4):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  162. NLRP3-Inflammasome Inhibition during Respiratory Virus Infection Abrogates Lung Immunopathology and Long-Term Airway Disease Development
    Authors: CA Malinczak, CF Schuler, AJ Duran, AJ Rasky, MM Mire, G Núñez, NW Lukacs, W Fonseca
    Viruses, 2021-04-16;13(4):.
    Species: Mouse
    Sample Types: BALF
  163. A NOVEL NOX/PHOX-CD38-NAADP-TFEB AXIS IMPORTANT FOR MACROPHAGE ACTIVATION DURING BACTERIAL PHAGOCYTOSIS
    Authors: M Najibi, HH Honwad, JA Moreau, SM Becker, JE Irazoqui
    Autophagy, 2021-04-13;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  164. Generation and utilization of a HEK-293T murine GM-CSF expressing cell line
    Authors: EK Robinson, S Covarrubia, S Zhou, S Carpenter
    PLoS ONE, 2021-04-09;16(4):e0249117.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  165. Exploiting pyocyanin to treat mitochondrial disease due to respiratory complex III dysfunction
    Authors: R Peruzzo, S Corrà, R Costa, M Brischigli, T Varanita, L Biasutto, C Rampazzo, D Ghezzi, L Leanza, M Zoratti, M Zeviani, C De Pittà, C Viscomi, R Costa, I Szabò
    Nature Communications, 2021-04-08;12(1):2103.
    Species: Mouse
    Sample Types: Plasma
  166. The anti-inflammatory cytokine interleukin-37 is an inhibitor of trained immunity
    Authors: G Cavalli, IW Tengesdal, M Gresnigt, T Nemkov, RJW Arts, J Domínguez-, R Molteni, D Stefanoni, E Cantoni, L Cassina, S Giugliano, K Schraa, TS Mills, EM Pietras, EZ Eisenmenss, L Dagna, A Boletta, A D'Alessand, LAB Joosten, MG Netea, CA Dinarello
    Cell Reports, 2021-04-06;35(1):108955.
    Species: Mouse
    Sample Types: Tissue Homogenates
  167. Combined Effects of Exercise and Phytoanabolic Extracts in Castrated Male and Female Mice
    Authors: JP Martins, LC Silva, MS Nunes, G Rübensam, JR Oliveira, RBM Silva, MM Campos
    Nutrients, 2021-04-02;13(4):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  168. Discovery and characterization of small molecule inhibitors of NLRP3 and NLRC4 inflammasomes
    Authors: M Sebastian-, H Wu, M Al Rahim, R Sanchez, K Kumar, RJ De Vita, GM Pasinetti
    The Journal of Biological Chemistry, 2021-03-26;0(0):100597.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  169. Hepatoprotective Effect of Mixture of Dipropyl Polysulfides in Concanavalin A-Induced Hepatitis
    Authors: D Arsenijevi, B Stojanovic, J Milovanovi, A Arsenijevi, M Simic, M Pergal, I Kodranov, O Cvetkovic, D Vojvodic, E Ristanovic, D Manojlovic, M Milovanovi, N Arsenijevi
    Nutrients, 2021-03-22;13(3):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  170. Roles of lung-recruited monocytes and pulmonary Vascular Endothelial Growth Factor (VEGF) in resolving Ventilator-Induced Lung Injury (VILI)
    Authors: CK Lin, TH Huang, CT Yang, CS Shi
    PLoS ONE, 2021-03-19;16(3):e0248959.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  171. &alpha-Phellandrene exhibits antinociceptive and tumor-reducing effects in a mouse model of oncologic pain
    Authors: FR Pinheiro-N, EM Lopes, BT Acha, LDS Gomes, WA Dias, ACD Reis Filho, BS Leal, DCDN Rodrigues, JDN Silva, D Dittz, PMP Ferreira, FRC Almeida
    Toxicology and Applied Pharmacology, 2021-03-17;418(0):115497.
    Species: Mouse
    Sample Types: Serum
  172. The AIM2 inflammasome exacerbates atherosclerosis in clonal haematopoiesis
    Authors: TP Fidler, C Xue, M Yalcinkaya, B Hardaway, S Abramowicz, T Xiao, W Liu, DG Thomas, MA Hajebrahim, J Pircher, C Silvestre-, AG Kotini, LL Luchsinger, Y Wei, M Westerterp, HW Snoeck, EP Papapetrou, C Schulz, S Massberg, O Soehnlein, B Ebert, RL Levine, MP Reilly, P Libby, N Wang, AR Tall
    Nature, 2021-03-17;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  173. STAT6-Dependent Exacerbation of House Dust Mite-Induced Allergic Airway Disease in Mice by Multi-Walled Carbon Nanotubes
    Authors: MD Ihrie, KS Duke, KA Shipkowski, DJ You, HY Lee, AJ Taylor-Jus, JC Bonner
    NanoImpact, 2021-03-13;22(0):.
    Species: Mouse
    Sample Types: BALF
  174. Proteomics reveals distinct mechanisms regulating the release of cytokines and alarmins during pyroptosis
    Authors: K Phulphagar, LI Kühn, S Ebner, A Frauenstei, JJ Swietlik, J Rieckmann, F Meissner
    Cell Reports, 2021-03-09;34(10):108826.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  175. Itaconate confers tolerance to late NLRP3 inflammasome activation
    Authors: M Bambouskov, L Potuckova, T Paulenda, M Kerndl, DA Mogilenko, K Lizotte, A Swain, S Hayes, RD Sheldon, H Kim, U Kapadnis, AE Ellis, C Isaguirre, S Burdess, A Laha, GK Amarasingh, V Chubukov, TP Roddy, MS Diamond, RG Jones, DM Simons, MN Artyomov
    Cell Reports, 2021-03-09;34(10):108756.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  176. Type I IFNs facilitate innate immune control of the opportunistic bacteria Burkholderia cenocepacia in the macrophage cytosol
    Authors: MG Dorrington, CJ Bradfield, JB Lack, B Lin, JJ Liang, T Starr, O Ernst, JL Gross, J Sun, AH Miller, O Steele-Mor, IDC Fraser
    PloS Pathogens, 2021-03-08;17(3):e1009395.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  177. Mitochondrial arginase-2 is essential for IL-10 metabolic reprogramming of inflammatory macrophages
    Authors: JK Dowling, R Afzal, LJ Gearing, MP Cervantes-, S Annett, GM Davis, C De Santi, N Assmann, K Dettmer, DJ Gough, GR Bantug, FI Hamid, FK Nally, CP Duffy, AL Gorman, AM Liddicoat, EC Lavelle, C Hess, PJ Oefner, DK Finlay, GP Davey, T Robson, AM Curtis, PJ Hertzog, BRG Williams, CE McCoy
    Nature Communications, 2021-03-05;12(1):1460.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  178. Small Immunomodulatory Molecules as Potential Therapeutics in Experimental Murine Models of Acute Lung Injury (ALI)/Acute Respiratory Distress Syndrome (ARDS)
    Authors: D Shah, P Das, S Acharya, B Agarwal, DJ Christense, SM Robertson, V Bhandari
    International Journal of Molecular Sciences, 2021-03-04;22(5):.
    Species: Mouse
    Sample Types: BALF
  179. Physalis angulata reduces the progression of chronic experimental periodontitis by immunomodulatory mechanisms
    Authors: PS Vieceli, PJ Lima Juiz, PS Sales Laur, RD Couto, TC Barbosa To, IM Ribeiro, MB Pereira So, CF Villarreal
    Journal of ethnopharmacology, 2021-03-03;0(0):113986.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  180. Sex-dependent differences in the gut microbiota following chronic nasal inflammation in adult mice
    Authors: Y Mishima, T Osaki, A Shimada, S Kamiya, S Hasegawa-I
    Scientific Reports, 2021-02-25;11(1):4640.
    Species: Mouse
    Sample Types: Serum
  181. Inflammatory, synaptic, motor, and behavioral alterations induced by gestational sepsis on the offspring at different stages of life
    Authors: MG Granja, LP Alves, M Leardini-T, ME Saul, LC Bortoni, FM de Moraes, EC Ferreira, BPT de Moraes, VZ da Silva, AFR Dos Santos, AR Silva, CF Gonçalves-, V Bambini-Ju, AS Weyrich, MT Rondina, GA Zimmerman, HC de Castro-
    Journal of Neuroinflammation, 2021-02-25;18(1):60.
    Species: Mouse
    Sample Types: Tissue Homogenates
  182. Sevoflurane preconditioning activates HGF/Met-mediated autophagy to attenuate hepatic ischemia-reperfusion injury in mice
    Authors: X Xiao, D Liu, S Chen, X Li, M Ge, W Huang
    Cellular Signalling, 2021-02-25;0(0):109966.
    Species: Mouse
    Sample Types: Tissue Homogenates
  183. NLRP6-associated host microbiota composition impacts in the intestinal barrier to systemic dissemination of Brucella abortus
    Authors: M Rungue, V Melo, D Martins, PC Campos, G Leles, I Galvão, V Mendes, M Aganetti, Á Pedersen, NRG Assis, R Santos, GD Cassali, ALB Godard, FS Martins, SC Oliveira, AT Vieira
    PloS Neglected Tropical Diseases, 2021-02-22;15(2):e0009171.
    Species: Mouse
    Sample Types: Tissue Homogenates
  184. Tim4 recognizes carbon nanotubes and mediates phagocytosis leading to granuloma formation
    Authors: S Omori, M Tsugita, Y Hoshikawa, M Morita, F Ito, SI Yamaguchi, Q Xie, O Noyori, T Yamaguchi, A Takada, T Saitoh, S Toyokuni, H Akiba, S Nagata, K Kinoshita, M Nakayama
    Cell Reports, 2021-02-09;34(6):108734.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  185. Dual Role of Interleukin-10 in Murine NZB/W F1 Lupus
    Authors: A Amend, N Wickli, AL Schäfer, DTL Sprenger, RA Manz, RE Voll, N Chevalier
    International Journal of Molecular Sciences, 2021-01-29;22(3):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  186. Fatty Acids and a High-Fat Diet Induce Epithelial-Mesenchymal Transition by Activating TGF&beta and &beta-Catenin in Liver Cells
    Authors: O Kwapisz, J Górka, A Korlatowic, J Kotlinowsk, A Waligórska, P Marona, N Pydyn, JW Dobrucki, J Jura, K Miekus
    International Journal of Molecular Sciences, 2021-01-28;22(3):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  187. Hypoxia-Induced S100A8 Expression Activates Microglial Inflammation and Promotes Neuronal Apoptosis
    Authors: JS Ha, HR Choi, IS Kim, EA Kim, SW Cho, SJ Yang
    International Journal of Molecular Sciences, 2021-01-26;22(3):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  188. Gasdermin D restricts Burkholderia cenocepacia infection in vitro and in vivo
    Authors: S Estfanous, K Krause, MNK Anne, M Eltobgy, K Caution, A Abu Khweek, K Hamilton, A Badr, K Daily, C Carafice, D Baetzhold, X Zhang, T Li, H Wen, MA Gavrilin, H Haffez, S Soror, AO Amer
    Scientific Reports, 2021-01-13;11(1):855.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  189. Disrupted Iron Metabolism and Mortality during Co-infection with Malaria and an Intestinal Gram-Negative Extracellular Pathogen
    Authors: LI Dos Santos, TA Torres, SQ Diniz, R Gonçalves, G Caballero-, G Núñez, RT Gazzinelli, KJ Maloy, L Ribeiro do
    Cell Reports, 2021-01-12;34(2):108613.
    Species: Mouse
    Sample Types: Serum
  190. Pra-C exerts analgesic effect through inhibiting microglial activation in anterior cingulate cortex in complete Freund's adjuvant-induced mouse model
    Authors: DJ Su, LF Li, SY Wang, Q Yang, YJ Wu, MG Zhao, L Yang
    Molecular pain, 2021-01-01;17(0):1744806921990.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  191. Severity of Experimental Autoimmune Uveitis Is Reduced by Pretreatment with Live Probiotic Escherichia coli Nissle 1917
    Authors: O Dusek, A Fajstova, A Klimova, P Svozilkova, T Hrncir, M Kverka, S Coufal, J Slemin, H Tlaskalova, JV Forrester, J Heissigero
    Cells, 2020-12-25;10(1):.
    Species: Mouse
    Sample Types: Tissue Culture Supernates
  192. Diet Rich in Simple Sugars Promotes Pro-Inflammatory Response via Gut Microbiota Alteration and TLR4 Signaling
    Authors: A Fajstova, N Galanova, S Coufal, J Malkova, M Kostovcik, M Cermakova, H Pelantova, M Kuzma, B Sediva, T Hudcovic, T Hrncir, H Tlaskalova, M Kverka, K Kostovciko
    Cells, 2020-12-16;9(12):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  193. TXNIP Regulates Natural Killer Cell-Mediated Innate Immunity by Inhibiting IFN-&gamma Production during Bacterial Infection
    Authors: DO Kim, JE Byun, WS Kim, MJ Kim, JH Choi, H Kim, E Choi, TD Kim, SR Yoon, JY Noh, YJ Park, J Lee, HJ Cho, HG Lee, SH Min, I Choi, H Jung
    International Journal of Molecular Sciences, 2020-12-14;21(24):.
    Species: Mouse
    Sample Types: Serum
  194. Active food ingredients production from cold pressed processing residues of Camellia oleifera and Camellia sinensis seeds for regulation of blood pressure and vascular function
    Authors: SS Chiang, LS Chen, CY Chu
    Chemosphere, 2020-12-11;267(0):129267.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  195. Ubiquitination of RIPK1 regulates its activation mediated by TNFR1 and TLRs signaling in distinct manners
    Authors: X Li, M Zhang, X Huang, W Liang, G Li, X Lu, Y Li, H Pan, L Shi, H Zhu, L Qian, B Shan, J Yuan
    Nature Communications, 2020-12-11;11(1):6364.
    Species: Mouse
    Sample Types: Serum
  196. Olive Leaf Extract, from Olea europaea L., Reduces Palmitate-Induced Inflammation via Regulation of Murine Macrophages Polarization
    Authors: P De Cicco, M Maisto, GC Tenore, A Ianaro
    Nutrients, 2020-11-28;12(12):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  197. Dual chemotherapy with benznidazole at suboptimal dose plus curcumin nanoparticles mitigates Trypanosoma cruzi-elicited chronic cardiomyopathy
    Authors: M Hernández, S Wicz, E Pérez Caba, MH Santamaría, RS Corral
    Parasitol Int, 2020-11-22;81(0):102248.
    Species: Mouse
    Sample Types: Tissue Homogenates
  198. Unique maternal immune and functional microbial profiles during prenatal stress
    Authors: AM Antonson, MV Evans, JD Galley, HJ Chen, TA Rajasekera, SM Lammers, VL Hale, MT Bailey, TL Gur
    Sci Rep, 2020-11-20;10(1):20288.
    Species: Mouse
    Sample Types: Tissue Homogenates
  199. Different experimental multiple trauma models induce comparable inflammation and organ injury
    Authors: B Relja, B Yang, K Bundkirche, B Xu, K Köhler, C Neunaber
    Sci Rep, 2020-11-19;10(1):20185.
    Species: Mouse
    Sample Types: Plasma
  200. Tau Pathology Drives Dementia Risk-Associated Gene Networks toward Chronic Inflammatory States and Immunosuppression
    Authors: JE Rexach, D Polioudaki, A Yin, V Swarup, TS Chang, T Nguyen, A Sarkar, L Chen, J Huang, LC Lin, W Seeley, JQ Trojanowsk, D Malhotra, DH Geschwind
    Cell Rep, 2020-11-17;33(7):108398.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  201. Inducing regulated necrosis and shifting macrophage polarization with anti-EMMPRIN antibody (161-pAb) and complement factors
    Authors: N Hijaze, M Ledersnaid, E Simanovich, S Kassem, MA Rahat
    J Leukoc Biol, 2020-11-17;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  202. Disrupting Bordetella Immunosuppression Reveals a Role for Eosinophils in Coordinating the Adaptive Immune Response in the Respiratory Tract
    Authors: MC Gestal, U Blas-Macha, HM Johnson, LN Rubin, KK Dewan, C Bryant, M Tiemeyer, ET Harvill
    Microorganisms, 2020-11-17;8(11):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  203. RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly
    Authors: Y Duan, L Zhang, D Angosto-Ba, P Pelegrín, G Núñez, Y He
    Cell Rep, 2020-11-17;33(7):108405.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  204. Riboflavin, vitamin B2, attenuates NLRP3, NLRC4, AIM2, and non-canonical inflammasomes by the inhibition of caspase-1 activity
    Authors: H Ahn, GS Lee
    Sci Rep, 2020-11-05;10(1):19091.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  205. Anti-Axl antibody treatment reduces the severity of experimental autoimmune encephalomyelitis
    Authors: JC DuBois, AK Ray, P Davies, B Shafit-Zag
    J Neuroinflammation, 2020-10-29;17(1):324.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  206. TNF Signaling Dictates Myeloid and Non-Myeloid Cell Crosstalk to Execute MCMV-Induced Extrinsic Apoptosis
    Authors: P Mandal, AL McCormick, ES Mocarski
    Viruses, 2020-10-28;12(11):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  207. Human recombinant interleukin-38 suppresses inflammation in mouse models of local and systemic disease
    Authors: DM de Graaf, RJA Maas, SP Smeekens, E Eisenmesse, JS Redzic, MM Helsen, NE Powers, S Li, V Kalabokis, MS Gresnigt, LAB Joosten, CA Dinarello, FL van de Vee
    Cytokine, 2020-10-28;137(0):155334.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  208. Repeated dermal application of the common preservative methylisothiazolinone triggers local inflammation, T cell influx, and prolonged mast cell-dependent tactile sensitivity in mice
    Authors: JM Kline, E Arriaga-Go, T Yangdon, B Boo, J Landry, M Saldías-Mo, N Neamonitak, H Mengistu, S Silverio, H Zacheis, D Pasha, T Martinov, BT Fife, D Chatterjea
    PLoS ONE, 2020-10-26;15(10):e0241218.
    Species: Mouse
    Sample Types: Cell Lysates
  209. The protective role of proton-sensing TDAG8 in the brain injury in a mouse ischemia reperfusion model
    Authors: K Sato, A Tobo, C Mogi, M Tobo, N Yamane, M Tosaka, H Tomura, DS Im, F Okajima
    Sci Rep, 2020-10-14;10(1):17193.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  210. The overexpression of TDP-43 in astrocytes causes neurodegeneration via a PTP1B-mediated inflammatory response
    Authors: S Lee, S Kim, HY Kang, HR Lim, Y Kwon, M Jo, YM Jeon, SR Kim, K Kim, CM Ha, S Lee, HJ Kim
    J Neuroinflammation, 2020-10-14;17(1):299.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  211. Simvastatin Posttreatment Controls Inflammation and Improves Bacterial Clearance in Experimental Sepsis
    Authors: FM de Jesus O, CF Gonçalves-, IMM de Moraes, PA Reis, VN Rocha, PT Bozza, AR Silva, HC de Castro
    Mediators Inflamm, 2020-10-14;2020(0):1839762.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  212. Staphylococcus aureus-Derived &alpha-Hemolysin Evokes Generation of Specialized Pro-resolving Mediators Promoting Inflammation Resolution
    Authors: PM Jordan, J Gerstmeier, S Pace, R Bilancia, Z Rao, F Börner, L Miek, Ó Gutiérrez-, V Arakandy, A Rossi, A Ialenti, C González-E, B Löffler, L Tuchscherr, CN Serhan, O Werz
    Cell Rep, 2020-10-13;33(2):108247.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  213. The Pseudomonas aeruginosa protease LasB directly activates IL-1&beta
    Authors: J Sun, DL LaRock, EA Skowronski, JM Kimmey, J Olson, Z Jiang, AJ O'Donoghue, V Nizet, CN LaRock
    EBioMedicine, 2020-09-23;60(0):102984.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  214. Deficiency of peroxiredoxin 2 exacerbates angiotensin II-induced abdominal aortic aneurysm
    Authors: SJ Jeong, MJ Cho, NY Ko, S Kim, IH Jung, JK Min, SH Lee, JG Park, GT Oh
    Exp. Mol. Med., 2020-09-14;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
  215. Standardized herbal extract PM014 alleviates fine dust-induced lung inflammation in mice
    Authors: YS Lee, D Min, SY Park, J Lee, H Bae
    BMC Complement Med Ther, 2020-09-07;20(1):270.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  216. Activation of the NLRP3 Inflammasome by Particles from the Echinococcus granulosus Laminated Layer
    Authors: C Casaravill, Á Pittini, D Rückerl, JE Allen, Á Díaz
    Infect. Immun., 2020-08-19;88(9):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  217. Neutrophil Extracellular Traps Impair Intestinal Barrier Function during Experimental Colitis
    Authors: EY Lin, HJ Lai, YK Cheng, KQ Leong, LC Cheng, YC Chou, YC Peng, YH Hsu, HS Chiang
    Biomedicines, 2020-08-05;8(8):.
    Species: Mouse
    Sample Types: Cell Lysates, Tissue Homogenates
  218. Metabolic competition between host and pathogen dictates inflammasome responses to fungal infection
    Authors: TM Tucey, J Verma, FAB Olivier, TL Lo, AAB Robertson, T Naderer, A Traven
    PLoS Pathog., 2020-08-04;16(8):e1008695.
    Species: Mouse
    Sample Types: Cell Culture Supernates, Tissue Homogenates
  219. A Clinical Metabolite of Azidothymidine Inhibits Experimental Choroidal Neovascularization and Retinal Pigmented Epithelium Degeneration
    Authors: S Narendran, F Pereira, P Yerramothu, I Apicella, SB Wang, A Varshney, KL Baker, KM Marion, M Ambati, VL Ambati, K Ambati, SR Sadda, BD Gelfand, J Ambati
    Invest. Ophthalmol. Vis. Sci., 2020-08-03;61(10):4.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  220. STAT3 serine phosphorylation is required for TLR4 metabolic reprogramming and IL-1&beta expression
    Authors: JJ Balic, H Albargy, K Luu, FJ Kirby, WSN Jayasekara, F Mansell, DJ Garama, D De Nardo, N Baschuk, C Louis, F Humphries, K Fitzgerald, E Latz, DJ Gough, A Mansell
    Nat Commun, 2020-07-30;11(1):3816.
    Species: Mouse
    Sample Types: Cell Lysate
  221. Essential role of Salmonella Enteritidis DNA adenine methylase in modulating inflammasome activation
    Authors: Y Guo, D Gu, T Huang, L Cao, X Zhu, Y Zhou, K Wang, X Kang, C Meng, X Jiao, Z Pan
    BMC Microbiol., 2020-07-28;20(1):226.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  222. Immunomodulatory Effect of a Salvia plebeia R. Aqueous Extract in Forced Swimming Exercise-induced Mice
    Authors: J Shin, OK Kim, S Kim, D Bae, J Lee, J Park, W Jun
    Nutrients, 2020-07-28;12(8):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  223. Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
    Authors: SB Kovacs, C Oh, VI Maltez, BD McGlaughon, A Verma, EA Miao, Y Aachoui
    Cell Rep, 2020-07-28;32(4):107967.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  224. MG53 suppresses interferon-&beta and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling
    Authors: M Sermershei, AD Kenney, PH Lin, TM McMichael, C Cai, K Gumpper, TMA Adesanya, H Li, X Zhou, KH Park, JS Yount, J Ma
    Nat Commun, 2020-07-17;11(1):3624.
    Species: Human
    Sample Types: Cell Culture Supernates
  225. Zinc Finger Protein St18 Protects against Septic Death by Inhibiting VEGF-A from Macrophages
    Authors: K Maruyama, H Kidoya, N Takemura, E Sugisawa, O Takeuchi, T Kondo, MMA Eid, H Tanaka, MM Martino, N Takakura, Y Takayama, S Akira, A Vandenbon, Y Kumagai
    Cell Rep, 2020-07-14;32(2):107906.
    Species: Mouse
    Sample Types: Serum
  226. Regorafenib Regulates AD Pathology, Neuroinflammation, and Dendritic Spinogenesis in Cells and a Mouse Model of AD
    Authors: KM Han, RJ Kang, H Jeon, HJ Lee, JS Lee, H Park, S Gak Jeon, K Suk, J Seo, HS Hoe
    Cells, 2020-07-09;9(7):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  227. GM-CSF Calibrates Macrophage Defense and Wound Healing Programs during Intestinal Infection and Inflammation
    Authors: T Castro-Dop, A Fleming, TW Dennison, JR Ferdinand, K Harcourt, BJ Stewart, Z Cader, ZK Tuong, C Jing, LSC Lok, RJ Mathews, A Portet, A Kaser, S Clare, MR Clatworthy
    Cell Rep, 2020-07-07;32(1):107857.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  228. Induction of ASC pyroptosis requires gasdermin D or caspase-1/11-dependent mediators and IFNbeta from pyroptotic macrophages
    Authors: C Zhang, C Zhao, X Chen, R Tao, S Wang, G Meng, X Liu, C Shao, X Su
    Cell Death Dis, 2020-06-18;11(6):470.
    Species: Mouse, Transgenic Mouse
    Sample Types: Cell Culture Supernates
  229. Enhancing the regenerative effectiveness of growth factors by local inhibition of interleukin-1 receptor signaling
    Authors: Z Julier, R Karami, B Nayer, YZ Lu, AJ Park, K Maruyama, GA Kuhn, R Müller, S Akira, MM Martino
    Sci Adv, 2020-06-12;6(24):eaba7602.
    Species: Mouse
    Sample Types: Tissue Homogenates
  230. TRPM5 Negatively Regulates Calcium-Dependent Responses in Lipopolysaccharide-Stimulated B Lymphocytes
    Authors: T Sakaguchi, R Okumura, C Ono, D Okuzaki, T Kawai, Y Okochi, N Tanimura, M Murakami, H Kayama, E Umemoto, H Kioka, T Ohtani, Y Sakata, K Miyake, Y Okamura, Y Baba, K Takeda
    Cell Rep, 2020-06-09;31(10):107755.
    Species: Mouse
    Sample Types: Serum
  231. Antitumor and Anti-Metastatic Effects of Citral-Loaded Nanostructured Lipid Carrier in 4T1-Induced Breast Cancer Mouse Model
    Authors: N Nordin, SK Yeap, HS Rahman, NR Zamberi, NE Mohamad, N Abu, MJ Masarudin, R Abdullah, NB Alitheen
    Molecules, 2020-06-09;25(11):.
    Species: Mouse
    Sample Types: Serum
  232. Sulforaphane elicts dual therapeutic effects on Renal Inflammatory Injury and crystal deposition in Calcium Oxalate Nephrocalcinosis
    Authors: H Liu, X Yang, K Tang, T Ye, C Duan, P Lv, L Yan, X Wu, Z Chen, J Liu, Y Deng, G Zeng, J Xing, Z Ye, H Xu
    Theranostics, 2020-06-05;10(16):7319-7334.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  233. The TSPO-NOX1 axis controls phagocyte-triggered pathological angiogenesis in the eye
    Authors: A Wolf, M Herb, M Schramm, T Langmann
    Nat Commun, 2020-06-01;11(1):2709.
    Species: Mouse
    Sample Types: Tissue Homogenates
  234. Progesterone Attenuates Stress-Induced NLRP3 Inflammasome Activation and Enhances Autophagy following Ischemic Brain Injury
    Authors: C Espinosa-G, F Atif, S Yousuf, I Sayeed, GN Neigh, DG Stein
    Int J Mol Sci, 2020-05-26;21(11):.
    Species: Mouse
    Sample Types: Cell Supernatants
  235. Mitophagy deficiency increases NLRP3 to induce brown fat dysfunction in mice
    Authors: MS Ko, JY Yun, IJ Baek, JE Jang, JJ Hwang, SE Lee, SH Heo, DA Bader, CH Lee, J Han, JS Moon, JM Lee, EG Hong, IK Lee, SW Kim, JY Park, SM Hartig, UJ Kang, DD Moore, EH Koh, KU Lee
    Autophagy, 2020-05-13;0(0):1-17.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  236. TNF-&alpha Pretreatment Improves the Survival and Function of Transplanted Human Neural Progenitor Cells Following Hypoxic-Ischemic Brain Injury
    Authors: M Kim, K Jung, Y Ko, IS Kim, K Hwang, JH Jang, JE Shin, KI Park
    Cells, 2020-05-11;9(5):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  237. N-GSDMD trafficking to neutrophil organelles facilitates IL-1&beta release independently of plasma membrane pores and pyroptosis
    Authors: M Karmakar, M Minns, EN Greenberg, J Diaz-Apont, K Pestonjama, JL Johnson, JK Rathkey, DW Abbott, K Wang, F Shao, SD Catz, GR Dubyak, E Pearlman
    Nat Commun, 2020-05-05;11(1):2212.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  238. The Role of ST2 Receptor in the Regulation of Brucella abortus Oral Infection
    Authors: R Santos, PC Campos, M Rungue, V Rocha, D Santos, V Mendes, FV Marinho, F Martins, MF Ricci, DCD Reis, GD Cassali, JC Alves-Filh, AT Vieira, SC Oliveira
    Pathogens, 2020-04-28;9(5):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  239. Region-Specific Proteome Changes of the Intestinal Epithelium during Aging and Dietary Restriction
    Authors: N Gebert, CW Cheng, JM Kirkpatric, D Di Fraia, J Yun, P Schädel, S Pace, GB Garside, O Werz, KL Rudolph, H Jasper, ÖH Yilmaz, A Ori
    Cell Rep, 2020-04-28;31(4):107565.
    Species: Mouse
    Sample Types: Tissue Homogenates
  240. TLR2 and caspase-1 signaling are critical for bacterial containment but not clearance during craniotomy-associated biofilm infection
    Authors: AL Aldrich, CE Heim, W Shi, RW Fallet, B Duan, T Kielian
    J Neuroinflammation, 2020-04-14;17(1):114.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  241. The C5a/C5aR2 axis promotes renal inflammation and tissue damage
    Authors: T Zhang, KY Wu, N Ma, LL Wei, M Garstka, W Zhou, K Li
    JCI Insight, 2020-04-09;5(7):.
    Species: Mouse
    Sample Types: Tissue Lysates
  242. (E)-2-Cyano-3-(1H-Indol-3-yl)-N-Phenylacrylamide, a Hybrid Compound Derived from Indomethacin and Paracetamol: Design, Synthesis and Evaluation of the Anti-Inflammatory Potential
    Authors: P Silva, M de Almeida, J Silva, S Albino, R Espírito-S, M Lima, C Villarreal, R Moura, V Santos
    Int J Mol Sci, 2020-04-08;21(7):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  243. M1 Polarization but Anti-LPS-Induced Inflammation and Anti-MCF-7 Breast Cancer Cell Growth Effects of Five Selected Polysaccharides
    Authors: HC Lin, JY Lin
    Evid Based Complement Alternat Med, 2020-03-25;2020(0):9450246.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  244. &beta-Amyloid Clustering around ASC Fibrils Boosts Its Toxicity in Microglia
    Authors: LL Friker, H Scheiblich, IV Hochheiser, R Brinkschul, D Riedel, E Latz, M Geyer, MT Heneka
    Cell Rep, 2020-03-17;30(11):3743-3754.e6.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  245. SIRT1 Alleviates LPS-Induced IL-1&beta Production by Suppressing NLRP3 Inflammasome Activation and ROS Production in Trophoblasts
    Authors: S Park, J Shin, J Bae, D Han, SR Park, J Shin, SK Lee, HW Park
    Cells, 2020-03-16;9(3):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  246. Angiotensin II induces RAW264.7 macrophage polarization to the M1?type through the connexin 43/NF?&kappaB pathway
    Authors: L Wu, K Chen, J Xiao, J Xin, L Zhang, X Li, L Li, J Si, L Wang, K Ma
    Mol Med Rep, 2020-03-12;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  247. Interleukin-1 Receptor-Induced Nitric Oxide Production in the Pancreas Controls Hyperglycemia Caused by Scorpion Envenomation
    Authors: MB Reis, J Elias-Oliv, MR Pastore, SG Ramos, LG Gardinassi, LH Faccioli
    Toxins (Basel), 2020-03-05;12(3):.
    Species: Mouse
    Sample Types: Serum
  248. Chronic oral administration of adipoRon reverses cognitive impairments and ameliorates neuropathology in an Alzheimer's disease mouse model
    Authors: RC Ng, M Jian, OK Ma, M Bunting, JS Kwan, GJ Zhou, K Senthilkum, A Iyaswamy, PK Chan, M Li, KM Leung, SS Kumar Dura, KS Lam, LW Chu, R Festenstei, SK Chung, KH Chan
    Mol. Psychiatry, 2020-03-04;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  249. Pharmacological LRH-1/Nr5a2 inhibition limits pro-inflammatory cytokine production in macrophages and associated experimental hepatitis
    Authors: J Schwaderer, TS Phan, A Glöckner, J Delp, M Leist, T Brunner, ME Delgado
    Cell Death Dis, 2020-02-28;11(2):154.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  250. Waterpipe Tobacco Smoke Inhalation Triggers Thrombogenicity, Cardiac Inflammation and Oxidative Stress in Mice: Effects of Flavouring
    Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, NE Zaaba, J Yasin, BH Ali
    Int J Mol Sci, 2020-02-14;21(4):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  251. Nose-Only Water-Pipe Smoke Exposure in Mice Elicits Renal Histopathological Alterations, Inflammation, Oxidative Stress, DNA Damage, and Apoptosis
    Authors: A Nemmar, S Beegam, P Yuvaraju, J Yasin, BH Ali, E Adeghate
    Front Physiol, 2020-02-11;11(0):46.
    Species: Mouse
    Sample Types: Tissue Homogenates
  252. Uric acid pathway activation during respiratory virus infection promotes Th2 immune response via innate cytokine production and ILC2 accumulation
    Authors: W Fonseca, CA Malinczak, CF Schuler, SKK Best, AJ Rasky, SB Morris, TX Cui, AP Popova, NW Lukacs
    Mucosal Immunol, 2020-02-11;0(0):.
    Species: Mouse
    Sample Types: BALF
  253. ACE2 activation protects against cognitive decline and reduces amyloid pathology in the Tg2576 mouse model of Alzheimer's disease.
    Authors: Evans C, Miners J, Piva G, Willis C, Heard D, Kidd E, Good M, Kehoe P
    Acta Neuropathol, 2020-01-25;139(3):485-502.
    Species: Mouse
    Sample Types: Tissue Homogenates
  254. Periostin Promotes Colorectal Tumorigenesis through Integrin-FAK-Src Pathway-Mediated YAP/TAZ Activation
    Authors: H Ma, J Wang, X Zhao, T Wu, Z Huang, D Chen, Y Liu, G Ouyang
    Cell Rep, 2020-01-21;30(3):793-806.e6.
    Species: Mouse
    Sample Types: Tissue Homogenates
  255. Detrimental Role of Nerve Injury-Induced Protein 1 in Myeloid Cells under Intestinal Inflammatory Conditions
    Authors: HJ Jung, JH Kang, S Pak, K Lee, JK Seong, SH Oh
    Int J Mol Sci, 2020-01-17;21(2):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  256. Maternal high fat diet consumption reduces liver alpha7 nicotinic cholinergic receptor expression and impairs insulin signalling in the offspring
    Authors: SO Costa, CM Souza, PG Lanza, JO Sartori, LM Ignacio-So, T Candreva, HG Rodrigues, AS Torsoni, M Milanski, MA Torsoni
    Sci Rep, 2020-01-08;10(1):48.
    Species: Mouse
    Sample Types: Tissue Homogenates
  257. I&kappaB? controls NLRP3 inflammasome activation via upregulation of the Nlrp3 gene
    Authors: J Kim, H Ahn, S Yu, JH Ahn, HJ Ko, MN Kweon, EJ Hong, BS An, E Lee, GS Lee
    Cytokine, 2020-01-07;127(0):154983.
    Species: Mouse
    Sample Types: Serum
  258. Eupatorin Suppressed Tumor Progression and Enhanced Immunity in a 4T1 Murine Breast Cancer Model
    Authors: N Abd Razak, SK Yeap, NB Alitheen, WY Ho, CY Yong, SW Tan, WS Tan, K Long
    Integr Cancer Ther, 2020-01-01;19(0):1534735420935.
    Species: Mouse
    Sample Types: Serum
  259. Enhancing the regenerative effectiveness of growth factors by local inhibition of interleukin-1 receptor signaling
    Authors: Z Julier, R Karami, B Nayer, YZ Lu, AJ Park, K Maruyama, GA Kuhn, R Müller, S Akira, MM Martino
    Sci Adv, 2020;6(24):eaba7602.
    Species: Mouse
    Sample Types: Tissue Homogenates
  260. Caveolin-1 gene therapy inhibits inflammasome activation to protect from bleomycin-induced pulmonary fibrosis
    Authors: X Lin, M Barravecch, R Matthew Ko, P Sime, DA Dean
    Sci Rep, 2019-12-23;9(1):19643.
    Species: Mouse
    Sample Types: BALF
  261. Sphingosine kinase-2 prevents macrophage cholesterol accumulation and atherosclerosis by stimulating autophagic lipid degradation
    Authors: K Ishimaru, K Yoshioka, K Kano, M Kurano, D Saigusa, J Aoki, Y Yatomi, N Takuwa, Y Okamoto, RL Proia, Y Takuwa
    Sci Rep, 2019-12-04;9(1):18329.
    Species: Mouse
    Sample Types: Plasma
  262. Maternal Obesity in Mice Exacerbates the Allergic Inflammatory Response in the Airways of Male Offspring
    Authors: RR E-Lacerda, CJ Teixeira, S Bordin, E Antunes, GF Anhê
    Nutrients, 2019-12-01;11(12):.
    Species: Mouse
    Sample Types: BALF
  263. Adiponectin Reverses the Hypothalamic Microglial Inflammation during Short-Term Exposure to Fat-Rich Diet
    Authors: H Lee, TH Tu, BS Park, S Yang, JG Kim
    Int J Mol Sci, 2019-11-15;20(22):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  264. The effects of oxygen concentration on cell death, anti-oxidant transcription, acute inflammation, and cell proliferation in precision-cut lung slices
    Authors: MJR Ruigrok, J Tomar, HW Frijlink, BN Melgert, WLJ Hinrichs, P Olinga
    Sci Rep, 2019-11-07;9(1):16239.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  265. A single systemic inflammatory insult causes acute motor deficits and accelerates disease progression in a mouse model of human tauopathy
    Authors: M Torvell, DW Hampton, P Connick, AMJ MacLullich, C Cunningham, S Chandran
    Alzheimers Dement (N Y), 2019-10-09;5(0):579-591.
    Species: Mouse
    Sample Types: Serum
  266. Relative Contributions of Extracellular and Internalized Bacteria to Early Macrophage Proinflammatory Responses to Streptococcus pneumoniae
    Authors: J Periselner, G Ercoli, T Pollard, S Chimalapat, E Camberlein, G Szylar, C Hyams, G Tomlinson, FC Petersen, RA Floto, M Noursadegh, JS Brown
    MBio, 2019-09-24;10(5):.
    Species: Mouse
    Sample Types: BALF
  267. PTP1B negatively regulates nitric oxide-mediated Pseudomonas aeruginosa killing by neutrophils
    Authors: L Yue, M Yan, ML Tremblay, TJ Lin, H Li, T Yang, X Song, T Xie, Z Xie
    PLoS ONE, 2019-09-18;14(9):e0222753.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  268. Nitric Oxide Modulates Metabolic Remodeling in Inflammatory Macrophages through TCA Cycle Regulation and Itaconate Accumulation
    Authors: JD Bailey, M Diotallevi, T Nicol, E McNeill, A Shaw, S Chuaiphich, A Hale, A Starr, M Nandi, E Stylianou, H McShane, S Davis, R Fischer, BM Kessler, J McCullagh, KM Channon, MJ Crabtree
    Cell Rep, 2019-07-02;28(1):218-230.e7.
    Species: Transgenic Mouse
    Sample Types: Cell Culture Supernates
  269. Oral administration of EPA-rich oil impairs collagen reorganization due to elevated production of IL-10 during skin wound healing in mice
    Authors: B Burger, CMC Kühl, T Candreva, RDS Cardoso, JR Silva, BG Castelucci, SR Consonni, HL Fisk, PC Calder, MAR Vinolo, HG Rodrigues
    Sci Rep, 2019-06-24;9(1):9119.
    Species: Mouse
    Sample Types: Tissue Homogenates
  270. Role of adipose tissue inflammation in fat pad loss induced by fasting in lean and mildly obese mice
    Authors: DR Lacerda, KA Costa, ALM Silveira, DF Rodrigues, AN Silva, JL Sabino, V Pinho, GB Menezes, DD Soares, MM Teixeira, AVM Ferreira
    J. Nutr. Biochem., 2019-06-21;72(0):108208.
    Species: Mouse
    Sample Types: Tissue Homogenates
  271. IL-33 drives group 2 innate lymphoid cell-mediated protection during Clostridium difficile infection
    Authors: AL Frisbee, MM Saleh, MK Young, JL Leslie, ME Simpson, MM Abhyankar, CA Cowardin, JZ Ma, P Pramoonjag, SD Turner, AP Liou, EL Buonomo, WA Petri
    Nat Commun, 2019-06-20;10(1):2712.
    Species: Mouse
    Sample Types: Tissue Homogenates
  272. Epigallocatechin-3-Gallate Prevents Acute Gout by Suppressing NLRP3 Inflammasome Activation and Mitochondrial DNA Synthesis
    Authors: HE Lee, G Yang, YB Park, HC Kang, YY Cho, HS Lee, JY Lee
    Molecules, 2019-06-06;24(11):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  273. Frontline Science: Acyl-CoA synthetase 1 exacerbates lipotoxic inflammasome activation in primary macrophages
    Authors: G Kalugotla, L He, KJ Weber, S Daemen, A Reller, B Razani, JD Schilling
    J. Leukoc. Biol., 2019-06-05;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  274. In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy
    Authors: VN Camargos, G Foureaux, DC Medeiros, VT da Silveir, CM Queiroz-Ju, ALB Matosinhos, AFA Figueiredo, CDF Sousa, TP Moreira, VF Queiroz, ACF Dias, KTO Santana, I Passos, ALCV Real, LC Silva, FAG Mourão, NT Wnuk, MAP Oliveira, S Macari, T Silva, GP Garlet, JA Jackman, FM Soriani, MFD Moraes, EMAM Mendes, FM Ribeiro, GMJ Costa, AL Teixeira, NJ Cho, ACP Oliveira, MM Teixeira, VV Costa, DG Souza
    EBioMedicine, 2019-05-23;0(0):.
    Species: Mouse
    Sample Types: Plasma
  275. Innate immune memory through TLR2 and NOD2 contributes to the control of Leptospira interrogans infection
    Authors: I Santecchia, F Vernel-Pau, O Rasid, J Quintin, M Gomes-Sole, IG Boneca, C Werts
    PLoS Pathog., 2019-05-20;15(5):e1007811.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  276. Newly defined ABCB5+ dermal mesenchymal stem cells promote healing of chronic iron overload wounds via secretion of interleukin-1 receptor antagonist
    Authors: S Vander Bek, JC de Vries, B Meier-Schi, P Meyer, D Jiang, A Sindrilaru, FF Ferreira, A Hainzl, S Schatz, J Muschhamme, NJ Scheurmann, P Kampilafko, AM Seitz, L Dürselen, A Ignatius, MA Kluth, C Ganss, M Wlaschek, K Singh, P Maity, NY Frank, MH Frank, K Scharffett
    Stem Cells, 2019-05-13;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
  277. Context-specific switch from anti- to pro-epileptogenic function of the P2Y1 receptor in experimental epilepsy
    Authors: M Alves, L De Diego G, G Conte, EM Jimenez-Ma, B D'Orsi, A Sanz-Rodri, JH Prehn, DC Henshall, T Engel
    J. Neurosci., 2019-05-02;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  278. Butyrate Protects Mice from Clostridium difficile-Induced Colitis through an HIF-1-Dependent Mechanism
    Authors: JL Fachi, JS Felipe, LP Pral, BK da Silva, RO Corrêa, MCP de Andrade, DM da Fonseca, PJ Basso, NOS Câmara, ÉL de Sales E, F Dos Santos, SES Guima, AM Thomas, JC Setubal, YT Magalhães, FL Forti, T Candreva, HG Rodrigues, MB de Jesus, SR Consonni, ADS Farias, P Varga-Weis, MAR Vinolo
    Cell Rep, 2019-04-16;27(3):750-761.e7.
    Species: Mouse
    Sample Types: Tissue Homogenates
  279. Human metapneumovirus activates NOD-like receptor protein 3 inflammasome via its small hydrophobic protein which plays a detrimental role during infection in mice
    Authors: VB Lê, J Dubois, C Couture, MH Cavanagh, O Uyar, A Pizzorno, M Rosa-Calat, MÈ Hamelin, G Boivin
    PLoS Pathog., 2019-04-09;15(4):e1007689.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  280. Elevated circulating TGF?1 during acute liver failure activates TGF?R2 on cortical neurons and exacerbates neuroinflammation and hepatic encephalopathy in mice
    Authors: M McMillin, S Grant, G Frampton, AD Petrescu, E Williams, B Jefferson, A Thomas, A Brahmarout, S DeMorrow
    J Neuroinflammation, 2019-04-02;16(1):69.
    Species: Mouse
    Sample Types: Tissue Homogenates
  281. The three cytokines IL-1?, IL-18, and IL-1? share related but distinct secretory routes
    Authors: VS Tapia, MJD Daniels, P Palazón-Ri, M Dewhurst, NM Luheshi, J Rivers-Aut, J Green, E Redondo-Ca, P Kaldis, G Lopez-Cast, D Brough
    J. Biol. Chem., 2019-04-02;294(21):8325-8335.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  282. Exercise-induced AMPK activation and IL-6 muscle production are disturbed in adiponectin knockout mice
    Authors: TA Diniz, JCJ Aquino Jún, FC Mosele, C Cabral-San, EA Lima Junio, AAS Teixeira, FS Lira, JC Rosa Neto
    Cytokine, 2019-03-20;119(0):71-80.
    Species: Mouse
    Sample Types: Tissue Homogenates
  283. HSP70 is a negative regulator of NLRP3 inflammasome activation
    Authors: P Martine, A Chevriaux, V Derangère, L Apetoh, C Garrido, F Ghiringhel, C Rébé
    Cell Death Dis, 2019-03-15;10(4):256.
    Species: Mouse
    Sample Types: Lavage Fluid
  284. Urolithin A attenuates memory impairment and neuroinflammation in APP/PS1 mice
    Authors: Z Gong, J Huang, B Xu, Z Ou, L Zhang, X Lin, X Ye, X Kong, D Long, X Sun, X He, L Xu, Q Li, A Xuan
    J Neuroinflammation, 2019-03-14;16(1):62.
    Species: Mouse
    Sample Types: Tissue Homogenates
  285. The NLRP3 inflammasome modulates glycolysis by increasing PFKFB3 in an IL-1?-dependent manner in macrophages
    Authors: OM Finucane, J Sugrue, A Rubio-Arai, MV Guillot-Se, MA Lynch
    Sci Rep, 2019-03-11;9(1):4034.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  286. Epithelium-specific MyD88 signaling, but not DCs or macrophages, control acute intestinal infection with Clostridium difficile
    Authors: P Mamareli, F Kruse, C Friedrich, N Smit, T Strowig, T Sparwasser, M Lochner
    Eur. J. Immunol., 2019-03-10;0(0):.
    Species: Mouse
    Sample Types: Serum
  287. Combinatory FK506 and Minocycline Treatment Alleviates Prion-Induced Neurodegenerative Events via Caspase-Mediated MAPK-NRF2 Pathway
    Authors: SZA Shah, D Zhao, G Taglialate, T Hussain, H Dong, N Sabir, MH Mangi, W Wu, M Lai, X Zhang, Y Duan, L Wang, X Zhou, L Yang
    Int J Mol Sci, 2019-03-06;20(5):.
    Species: Hamster
    Sample Types: Tissue Homogenates
  288. Interleukin-37 monomer is the active form for reducing innate immunity
    Authors: EZ Eisenmesse, A Gottschlic, JS Redzic, N Paukovich, JC Nix, T Azam, L Zhang, R Zhao, JS Kieft, E The, X Meng, CA Dinarello
    Proc. Natl. Acad. Sci. U.S.A., 2019-02-28;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  289. Gum Arabic Ameliorates Impaired Coagulation and Cardiotoxicity Induced by Water-Pipe Smoke Exposure in Mice
    Authors: A Nemmar, S Al-Salam, S Beegam, P Yuvaraju, BH Ali
    Front Physiol, 2019-02-25;10(0):53.
    Species: Mouse
    Sample Types: Tissue Homogenates
  290. Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host
    Authors: M Ahn, DE Anderson, Q Zhang, CW Tan, BL Lim, K Luko, M Wen, WN Chia, S Mani, LC Wang, JHJ Ng, RM Sobota, CA Dutertre, F Ginhoux, ZL Shi, AT Irving, LF Wang
    Nat Microbiol, 2019-02-25;0(0):.
    Species: Human
    Sample Types: Cell Culture Supernates
  291. Honokiol-Mediated Mitophagy Ameliorates Postoperative Cognitive Impairment Induced by Surgery/Sevoflurane via Inhibiting the Activation of NLRP3 Inflammasome in the Hippocampus
    Authors: JS Ye, L Chen, YY Lu, SQ Lei, M Peng, ZY Xia
    Oxid Med Cell Longev, 2019-02-24;2019(0):8639618.
    Species: Mouse
    Sample Types: Tissue Secretion
  292. Structural basis for species-selective targeting of Hsp90 in a pathogenic fungus
    Authors: L Whitesell, N Robbins, DS Huang, CA McLellan, T Shekhar-Gu, EV LeBlanc, CS Nation, R Hui, A Hutchinson, C Collins, S Chatterjee, R Trilles, JL Xie, DJ Krysan, S Lindquist, JA Porco, U Tatu, LE Brown, J Pizarro, LE Cowen
    Nat Commun, 2019-01-24;10(1):402.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  293. Leishmania Lipophosphoglycan Triggers Caspase-11 and the Non-canonical Activation of the NLRP3 Inflammasome
    Authors: RVH de Carvalh, WA Andrade, DS Lima-Junio, M Dilucca, CV de Oliveir, K Wang, PM Nogueira, JN Rugani, RP Soares, SM Beverley, F Shao, DS Zamboni
    Cell Rep, 2019-01-08;26(2):429-437.e5.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  294. In�Vitro Macrophage Assay Predicts the In�Vivo Anti-inflammatory Potential of Exosomes from Human Mesenchymal Stromal Cells
    Authors: N Pacienza, RH Lee, EH Bae, DK Kim, Q Liu, DJ Prockop, G Yannarelli
    Mol Ther Methods Clin Dev, 2018-12-15;13(0):67-76.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  295. Role of a fluid-phase PRR in fighting an intracellular pathogen: PTX3 in Shigella infection
    Authors: V Ciancarell, L Lembo-Fazi, I Paciello, AK Bruno, S Jaillon, S Berardi, M Barbagallo, S Meron-Suda, D Cohen, A Molinaro, G Rossi, C Garlanda, ML Bernardini
    PLoS Pathog., 2018-12-07;14(12):e1007469.
    Species: Mouse
    Sample Types: Tissue Homogenates
  296. Genetically Engineered Resveratrol-Enriched Rice Inhibits Neuroinflammation in Lipopolysaccharide-Activated BV2 Microglia Via Downregulating Mitogen-Activated Protein Kinase-Nuclear Factor Kappa B Signaling Pathway
    Authors: L Subedi, SH Baek, SY Kim
    Oxid Med Cell Longev, 2018-12-03;2018(0):8092713.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  297. Enzymatic Activity Is Not Required for Phospholipase D Mediated TNF-? Regulation and Myocardial Healing
    Authors: M Klier, S Gorressen, MA Urbahn, D Barbosa, M Ouwens, JW Fischer, M Elvers
    Front Physiol, 2018-11-29;9(0):1698.
    Species: Mouse
    Sample Types: Plasma
  298. The Mitochondrial Apoptotic Effectors BAX/BAK Activate Caspase-3 and -7 to Trigger NLRP3 Inflammasome and Caspase-8 Driven IL-1? Activation
    Authors: JE Vince, D De Nardo, W Gao, AJ Vince, C Hall, K McArthur, D Simpson, S Vijayaraj, LM Lindqvist, P Bouillet, MA Rizzacasa, SM Man, J Silke, SL Masters, G Lessene, DCS Huang, DHD Gray, BT Kile, F Shao, KE Lawlor
    Cell Rep, 2018-11-27;25(9):2339-2353.e4.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  299. A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling
    Authors: B Koch, AA Barugahare, TL Lo, C Huang, RB Schittenhe, DR Powell, TH Beilharz, A Traven
    Cell Rep, 2018-11-20;25(8):2244-2258.e7.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  300. Omega-9 Oleic Acid, the Main Compound of Olive Oil, Mitigates Inflammation during Experimental Sepsis
    Authors: IM Medeiros-d, CF Gonçalves-, ARM Kurz, FMJ Oliveira, VHP de Abreu, RC Torres, VF Carvalho, V Estato, PT Bozza, M Sperandio, HC de Castro-, AR Silva
    Oxid Med Cell Longev, 2018-11-13;2018(0):6053492.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  301. A non-canonical autophagy-dependent role of the ATG16L1T300A variant in urothelial vesicular trafficking and uropathogenic Escherichia coli persistence
    Authors: C Wang, KA Bauckman, ASB Ross, JW Symington, MM Ligon, G Scholtes, A Kumar, HW Chang, J Twentyman, BE Fashemi, RJ Xavier, IU Mysorekar
    Autophagy, 2018-11-08;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  302. Ibuprofen prevents progression of ataxia telangiectasia symptoms in ATM-deficient mice
    Authors: CW Hui, X Song, F Ma, X Shen, K Herrup
    J Neuroinflammation, 2018-11-06;15(1):308.
    Species: Mouse
    Sample Types: Tissue Homogenates
  303. Human Defensin-5 Blocks Ethanol and Colitis-Induced Dysbiosis, Tight Junction Disruption and Inflammation in Mouse Intestine
    Authors: PK Shukla, AS Meena, V Rao, RG Rao, L Balazs, R Rao
    Sci Rep, 2018-11-02;8(1):16241.
    Species: Mouse
    Sample Types: Plasma
  304. Carbon monoxide-induced TFEB nuclear translocation enhances mitophagy/mitochondrial biogenesis in hepatocytes and ameliorates inflammatory liver injury
    Authors: HJ Kim, Y Joe, SY Rah, SK Kim, SU Park, J Park, J Kim, J Ryu, GJ Cho, YJ Surh, SW Ryter, UH Kim, HT Chung
    Cell Death Dis, 2018-10-17;9(11):1060.
    Species: Mouse
    Sample Types: Serum
  305. Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy
    Authors: F Sato-Kanek, X Wang, S Yao, T Hosoya, FS Lao, K Messer, M Pu, NM Shukla, HB Cottam, M Chan, DA Carson, M Corr, T Hayashi
    Biomed Res Int, 2018-10-10;2018(0):8091283.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  306. Protective Effects of Anti-IL17 on Acute Lung Injury Induced by LPS in Mice
    Authors: RF Righetti, TM Dos Santos, LDN Camargo, LRCRB Aristótele, S Fukuzaki, FCR de Souza, FPR Santana, MVR de Agrela, MM Cruz, MIC Alonso-Val, IS Genaro, BM Saraiva-Ro, EA Leick, MA Martins, CM Prado, IFLC Tibério
    Front Pharmacol, 2018-10-04;9(0):1021.
    Species: Mouse
    Sample Types: Tissue Homogenates
  307. Regulation of S100A8 Stability by RNF5 in Intestinal Epithelial Cells Determines Intestinal Inflammation and Severity of Colitis
    Authors: Y Fujita, A Khateb, Y Li, R Tinoco, T Zhang, H Bar-Yoseph, MA Tam, Y Chowers, E Sabo, S Gerassy-Va, E Starosvets, B James, K Brown, SS Shen-Orr, LM Bradley, PA Tessier, ZA Ronai
    Cell Rep, 2018-09-18;24(12):3296-3311.e6.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  308. Arhalofenate acid inhibits monosodium urate crystal-induced inflammatory responses through activation of AMP-activated protein kinase (AMPK) signaling
    Authors: C McWherter, YJ Choi, RL Serrano, SK Mahata, R Terkeltaub, R Liu-Bryan
    Arthritis Res. Ther., 2018-09-06;20(1):204.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  309. Disabled-2 (DAB2) Overexpression Inhibits Monocyte-Derived Dendritic Cells' Function in Vogt-Koyanagi-Harada Disease
    Authors: S Yi, R Chang, J Hu, Y Qiu, Q Wang, Q Cao, G Yuan, G Su, C Zhou, Y Wang, A Kijlstra, P Yang
    Invest. Ophthalmol. Vis. Sci., 2018-09-04;59(11):4662-4669.
    Species: Human
    Sample Types: Cell Culture Supernates
  310. The histamine H3R antagonist DL77 attenuates autistic behaviors in a prenatal valproic acid-induced mouse model of autism
    Authors: N Eissa, P Jayaprakas, S Azimullah, SK Ojha, M Al-Houqani, FY Jalal, D ?a?ewska, K Kie?-Konon, B Sadek
    Sci Rep, 2018-08-30;8(1):13077.
    Species: Mouse
    Sample Types:
  311. NADPH Oxidase and Guanylate Binding Protein 5 Restrict Survival of Avirulent Type III Strains of Toxoplasma gondii in Naive Macrophages
    Authors: SK Matta, K Patten, Q Wang, BH Kim, JD MacMicking, LD Sibley
    MBio, 2018-08-28;9(4):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  312. Myeloperoxidase deficiency attenuates systemic and dietary iron-induced adverse effects
    Authors: X Xiao, P Saha, BS Yeoh, JA Hipp, V Singh, M Vijay-Kuma
    J. Nutr. Biochem., 2018-08-21;62(0):28-34.
    Species: Mouse
    Sample Types: Tissue Homogenates
  313. Helminths-based bi-functional molecule, tuftsin-phosphorylcholine (TPC), ameliorates an established murine arthritis
    Authors: M Blank, T Bashi, J Lachnish, D Ben-Ami-Sh, O Shovman, M Fridkin, M Eisenstein, A Volkov, I Barshack, Y Shoenfeld
    PLoS ONE, 2018-08-08;13(8):e0200615.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  314. Extracellular ATP is a danger signal activating P2X7 receptor in a LPS mediated inflammation (ARDS/ALI)
    Authors: S Cicko, TC Köhler, CK Ayata, T Müller, N Ehrat, A Meyer, M Hossfeld, A Zech, F Di Virgili, M Idzko
    Oncotarget, 2018-07-17;9(55):30635-30648.
    Species: Mouse
    Sample Types: BALF
  315. Apigenin Retards Atherogenesis by Promoting ABCA1-Mediated Cholesterol Efflux and Suppressing Inflammation
    Authors: K Ren, T Jiang, HF Zhou, Y Liang, GJ Zhao
    Cell. Physiol. Biochem., 2018-07-05;47(5):2170-2184.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  316. Targeting the IL33-NLRP3 axis improves therapy for experimental cerebral malaria
    Authors: P Strangward, MJ Haley, MG Albornoz, J Barrington, T Shaw, R Dookie, L Zeef, SM Baker, E Winter, TC Tzeng, DT Golenbock, SM Cruickshan, SM Allan, A Craig, FY Liew, D Brough, KN Couper
    Proc. Natl. Acad. Sci. U.S.A., 2018-06-28;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  317. Induction of endoplasmic reticulum stress under endotoxin tolerance increases inflammatory responses and decreases Pseudomonas aeruginosa pneumonia
    Authors: S Kim, Y Joe, SU Park, SO Jeong, JK Kim, SH Park, HO Pae, YJ Surh, J Shin, HT Chung
    J. Leukoc. Biol., 2018-06-20;0(0):.
    Species: Mouse
    Sample Types: BALF
  318. Choline transport links macrophage phospholipid metabolism and inflammation
    Authors: SA Snider, KD Margison, P Ghorbani, ND LeBlond, C O'Dwyer, JR Nunes, T Nguyen, H Xu, SA Bennett, MD Fullerton
    J. Biol. Chem., 2018-06-07;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  319. MCC950, a specific small molecule inhibitor of NLRP3 inflammasome attenuates colonic inflammation in spontaneous colitis mice
    Authors: AP Perera, R Fernando, T Shinde, R Gundamaraj, B Southam, SS Sohal, AAB Robertson, K Schroder, D Kunde, R Eri
    Sci Rep, 2018-06-05;8(1):8618.
    Species: Mouse
    Sample Types: Tissue Homogenates
  320. Activation of M1 macrophages play a critical role in the initiation of acute lung injury
    Authors: HL Lu, XY Huang, YF Luo, WP Tan, PF Chen, YB Guo
    Biosci. Rep., 2018-04-27;0(0):.
    Species: Mouse
    Sample Types: Serum
  321. Parkin deficiency modulates NLRP3 inflammasome activation by attenuating an A20-dependent negative feedback loop
    Authors: F Mouton-Lig, T Rosazza, J Sepulveda-, A Ieang, SM Hassoun, E Claire, G Mangone, A Brice, PP Michel, JC Corvol, O Corti
    Glia, 2018-04-17;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  322. Jugular arginine infusion relieves lipopolysaccharide-triggered inflammatory stress and improves immunity status of lactating dairy cows
    Authors: FF Zhao, TY Wu, HR Wang, LY Ding, G Ahmed, HW Li, W Tian, YZ Shen
    J. Dairy Sci., 2018-04-05;0(0):.
    Species: Bovine
    Sample Types: Serum
  323. Analogous corticosteroids, 9A and EK100, derived from solid-state-cultured mycelium of Antrodia camphorata inhibit proinflammatory cytokine expression in macrophages
    Authors: ST Kao, YH Kuo, SD Wang, HJ Hong, LJ Lin
    Cytokine, 2018-03-30;108(0):136-144.
    Species: Mouse
    Sample Types: BALF
  324. HMGB1/IL-1? complexes in plasma microvesicles modulate immune responses to burn injury
    Authors: LG Coleman, R Maile, SW Jones, BA Cairns, FT Crews
    PLoS ONE, 2018-03-30;13(3):e0195335.
    Species: Mouse
    Sample Types: Plasma
  325. Artemisia Extract Suppresses NLRP3 and AIM2 Inflammasome Activation by Inhibition of ASC Phosphorylation
    Authors: SB Kwak, S Koppula, EJ In, X Sun, YK Kim, MK Kim, KH Lee, TB Kang
    Mediators Inflamm., 2018-03-04;2018(0):6054069.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  326. FOXO3-dependent apoptosis limits alcohol-induced liver inflammation by promoting infiltrating macrophage differentiation
    Authors: Z Li, J Zhao, S Zhang, SA Weinman
    Cell Death Discov, 2018-02-13;4(0):16.
    Species: Mouse
    Sample Types: Serum
  327. Saturated Fatty Acids Undergo Intracellular Crystallization and Activate the NLRP3 Inflammasome in Macrophages
    Authors: T Karasawa, A Kawashima, F Usui-Kawan, S Watanabe, H Kimura, R Kamata, K Shirasuna, Y Koyama, A Sato-Tomit, T Matsuzaka, H Tomoda, SY Park, N Shibayama, H Shimano, T Kasahara, M Takahashi
    Arterioscler. Thromb. Vasc. Biol., 2018-02-08;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  328. Age-related cognitive impairment is associated with long-term neuroinflammation and oxidative stress in a mouse model of episodic systemic inflammation
    Authors: JC d'Avila, LD Siqueira, A Mazeraud, EP Azevedo, D Foguel, HC Castro-Far, T Sharshar, F Chrétien, FA Bozza
    J Neuroinflammation, 2018-01-30;15(1):28.
    Species: Mouse
    Sample Types: Tissue Homogenates
  329. Human caspase-4 detects tetra-acylated LPS and cytosolic Francisella and functions differently from murine caspase-11
    Authors: B Lagrange, S Benaoudia, P Wallet, F Magnotti, A Provost, F Michal, A Martin, F Di Lorenzo, BF Py, A Molinaro, T Henry
    Nat Commun, 2018-01-16;9(1):242.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  330. Unique metabolic activation of adipose tissue macrophages in obesity promotes inflammatory responses
    Authors: L Boutens, GJ Hooiveld, S Dhingra, RA Cramer, MG Netea, R Stienstra
    Diabetologia, 2018-01-14;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  331. Necroptosis promotes autophagy-dependent upregulation of DAMP and results in immunosurveillance
    Authors: SY Lin, SY Hsieh, YT Fan, WC Wei, PW Hsiao, DH Tsai, TS Wu, NS Yang
    Autophagy, 2017-12-31;0(0):0.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  332. Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection
    Authors: EE Hornick, B Banoth, AM Miller, ZR Zacharias, N Jain, ME Wilson, KN Gibson-Cor, KL Legge, GA Bishop, FS Sutterwala, SL Cassel
    J. Immunol., 2017-12-27;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  333. Neuronal ICAM-5 Inhibits Microglia Adhesion and Phagocytosis and Promotes an Anti-inflammatory Response in LPS Stimulated Microglia
    Authors: S Paetau, T Rolova, L Ning, CG Gahmberg
    Front Mol Neurosci, 2017-12-22;10(0):431.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  334. The Absence of NOD1 Enhances Killing of Aspergillus fumigatus Through Modulation of Dectin-1 Expression
    Authors: MS Gresnigt, M Jaeger, RK Subbarao M, O Rasid, G Jouvion, C Fitting, WJG Melchers, TD Kanneganti, A Carvalho, O Ibrahim-Gr, FL van de Vee
    Front Immunol, 2017-12-13;8(0):1777.
    Species: Mouse
    Sample Types: BALF
  335. CRISPR/Cas9 mediated mutation of mouse IL-1? nuclear localisation sequence abolishes expression
    Authors: MJD Daniels, AD Adamson, N Humphreys, D Brough
    Sci Rep, 2017-12-06;7(1):17077.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  336. Natural killer cell-intrinsic type I IFN signaling controls Klebsiella pneumoniae growth during lung infection
    Authors: M Ivin, A Dumigan, FN de Vasconc, F Ebner, M Borroni, A Kavirayani, KN Przybyszew, RJ Ingram, S Lienenklau, U Kalinke, D Stoiber, JA Bengoechea, P Kovarik
    PLoS Pathog., 2017-11-07;13(11):e1006696.
    Species: Mouse
    Sample Types: Tissue Homogenates
  337. Respiratory syncytial virus infection of newborn CX3CR1-deficent mice induces a pathogenic pulmonary innate immune response
    Authors: S Das, M Raundhal, J Chen, TB Oriss, R Huff, JV Williams, A Ray, P Ray
    JCI Insight, 2017-09-07;2(17):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  338. CLEC5A is a critical receptor in innate immunity against Listeria infection
    Authors: ST Chen, FJ Li, TY Hsu, SM Liang, YC Yeh, WY Liao, TY Chou, NJ Chen, M Hsiao, WB Yang, SL Hsieh
    Nat Commun, 2017-08-21;8(1):299.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  339. Nitric Oxide Modulates Macrophage Responses to Mycobacterium tuberculosis Infection through Activation of HIF-1? and Repression of NF-?B
    Authors: J Braverman, SA Stanley
    J. Immunol., 2017-07-28;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  340. The dataset describes: HIF-1 ? expression and LPS mediated cytokine production in MKP-1 deficient bone marrow derived murine macrophages
    Authors: H Talwar, C Bauerfeld, Y Liu, L Samavati
    Data Brief, 2017-07-20;14(0):56-61.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  341. Cathelicidins Inhibit Escherichia coli-Induced TLR2 and TLR4 Activation in a Viability-Dependent Manner
    Authors: M Coorens, VAF Schneider, AM de Groot, A van Dijk, M Meijerink, JM Wells, MR Scheenstra, EJA Veldhuizen, HP Haagsman
    J. Immunol., 2017-07-14;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  342. Intramembrane attenuation of the TLR4-TLR6 dimer impairs receptor assembly and reduces microglia mediated neurodegeneration
    Authors: L Shmuel-Gal, Y Klug, Z Porat, M Charni, B Zarmi, Y Shai
    J. Biol. Chem., 2017-06-27;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  343. MyD88-dependent pro-interleukin-1? induction in dendritic cells exposed to food-grade synthetic amorphous silica
    Authors: HC Winkler, J Kornprobst, P Wick, LM von Moos, I Trantakis, EM Schraner, B Bathke, H Hochrein, M Suter, H Naegeli
    Part Fibre Toxicol, 2017-06-23;14(1):21.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  344. Combination of a high-fat diet with sweetened condensed milk exacerbates inflammation and insulin resistance induced by each separately in mice
    Authors: LN Masi, AR Martins, AR Crisma, CL do Amaral, MR Davanso, TDA Serdan, RDC da Cunha d, MM Cruz, MIC Alonso-Val, RP Torres, J Mancini-Fi, JNB Pereira, MM da Silva R, EA Liberti, SM Hirabara, R Curi
    Sci Rep, 2017-06-21;7(1):3937.
    Species: Mouse
    Sample Types: Tissue Homogenates
  345. The anti-inflammatory and immunomodulatory potential of braylin: Pharmacological properties and mechanisms by in silico, in vitro and in vivo approaches
    Authors: RF Espírito-S, CS Meira, RDS Costa, OP Souza Filh, AF Evangelist, GHG Trossini, GM Ferreira, EDS Velozo, CF Villarreal, MB Pereira So
    PLoS ONE, 2017-06-08;12(6):e0179174.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  346. Elevated prostaglandin E2 post-bone marrow transplant mediates interleukin-1?-related lung injury
    Authors: GJ Martínez-C, QM Taylor, CA Wilke, AB Podsiad, BB Moore
    Mucosal Immunol, 2017-06-07;0(0):.
    Species: Mouse
    Sample Types: BALF
  347. Myeloid-derived miR-223 regulates intestinal inflammation via repression of the NLRP3 inflammasome
    Authors: V Neudecker, M Haneklaus, O Jensen, L Khailova, JC Masterson, H Tye, K Biette, P Jedlicka, KS Brodsky, ME Gerich, M Mack, AAB Robertson, MA Cooper, GT Furuta, CA Dinarello, LA O'Neill, HK Eltzschig, SL Masters, EN McNamee
    J. Exp. Med., 2017-05-09;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  348. IL-24 Promotes Pseudomonas aeruginosa Keratitis in C57BL/6 Mouse Corneas
    Authors: BX Ross, N Gao, X Cui, TJ Standiford, J Xu, FX Yu
    J. Immunol, 2017-03-22;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  349. Cerium Oxide Nanoparticles in Lung Acutely Induce Oxidative Stress, Inflammation, and DNA Damage in Various Organs of Mice
    Authors: A Nemmar, P Yuvaraju, S Beegam, MA Fahim, BH Ali
    Oxid Med Cell Longev, 2017-03-14;2017(0):9639035.
    Species: Mouse
    Sample Types: Tissue Homogenates
  350. The Carbohydrate Lectin Receptor, Dectin-1, Mediates Immune Response to Exserohilum rostratum
    Infect. Immun, 2017-02-23;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  351. Active MLKL triggers the NLRP3 inflammasome in a cell-intrinsic manner
    Authors: SA Conos, KW Chen, D De Nardo, H Hara, L Whitehead, G N£¤ez, SL Masters, JM Murphy, K Schroder, DL Vaux, KE Lawlor, LM Lindqvist, JE Vince
    Proc. Natl. Acad. Sci. U.S.A, 2017-01-17;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  352. LRP1 modulates the microglial immune response via regulation of JNK and NF-?B signaling pathways
    J Neuroinflammation, 2016-12-08;13(1):304.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  353. NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus
    Eur. J. Immunol., 2016-12-05;0(0):.
    Species: Mouse
    Sample Types: Serum
  354. Differential humoral and cellular immunity induced by vaccination using plasmid DNA and protein recombinant expressing the NS3 protein of dengue virus type 3
    J. Biomed. Sci, 2016-12-01;23(1):85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  355. Advax, a Delta Inulin Microparticle, Potentiates In-built Adjuvant Property of Co-administered Vaccines
    EBioMedicine, 2016-12-01;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  356. Immunogenic Dendritic Cell Generation from Pluripotent Stem Cells by Ectopic Expression of Runx3
    Authors: Istvan Szatmari
    J. Immunol., 2016-11-16;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  357. Palmitate promotes inflammatory responses and cellular senescence in cardiac fibroblasts
    Authors: Arne Yndestad
    Biochim. Biophys. Acta, 2016-11-12;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  358. Indoor secondary organic aerosols formation from ozonolysis of monoterpene: An example of d-limonene with ammonia and potential impacts on pulmonary inflammations
    Authors: Rujin Huang
    Sci. Total Environ., 2016-11-11;0(0):.
    Species: Mouse
    Sample Types: BALF
  359. Carvacrol reduces irinotecan-induced intestinal mucositis through inhibition of inflammation and oxidative damage via TRPA1 receptor activation
    Authors: Jand Venes R Medeiros
    Chem. Biol. Interact., 2016-11-09;260(0):129-140.
    Species: Mouse
    Sample Types: Tissue Homogenates
  360. Chrysin promotes attenuation of depressive-like behavior and hippocampal dysfunction resulting from olfactory bulbectomy in mice
    Authors: Silvana Peterini Boeira
    Chem. Biol. Interact., 2016-11-03;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  361. Molecular Basis of Acute Cystitis Reveals Susceptibility Genes and Immunotherapeutic Targets.
    Authors: Ines Ambite, Manoj Puthia, Karoly Nagy, Caterina Cafaro, Aftab Nadeem, Daniel S C Butler, Gustav Rydström, Nina A Filenko, Björn Wullt, Thomas Miethke, Catharina Svanborg
    PloS Pathogens, 2016-10-12;0(0):1553-7374.
    Species: Mouse
    Sample Types: Urine
  362. Polarization of macrophages towards M2 phenotype is favored by reduction in iPLA2?
    J Biol Chem, 2016-09-20;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  363. Dental Calculus Stimulates Interleukin-1? Secretion by Activating NLRP3 Inflammasome in Human and Mouse Phagocytes
    Authors: JL Montenegro, A Yoshimura, Z Sm, T Kaneko, Y Ozaki, T Ukai, T Miyazaki, E Latz, Y Hara
    PLoS ONE, 2016-09-15;11(9):e0162865.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  364. Klebsiella pneumoniae Siderophores Induce Inflammation, Bacterial Dissemination, and HIF-1? Stabilization during Pneumonia
    MBio, 2016-09-13;7(5):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  365. P2X7 receptor-dependent tuning of gut epithelial responses to infection
    Authors: SW Huang, C Walker, J Pennock, K Else, W Muller, MJ Daniels, C Pellegrini, D Brough, G Lopez-Cast, SM Cruickshan
    Immunol. Cell Biol, 2016-08-25;95(2):178-188.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  366. Caspase-2 deficiency accelerates chemically induced liver cancer in mice
    Cell Death Differ, 2016-08-12;0(0):.
    Species: Mouse
    Sample Types: Serum
  367. The circadian clock regulates inflammatory arthritis
    FASEB J, 2016-08-03;0(0):.
    Species: Mouse
    Sample Types: Serum
  368. Transcriptional and functional characterization of CD137L-dendritic cells identifies a novel dendritic cell phenotype
    Sci Rep, 2016-07-19;6(0):29712.
    Species: Human
    Sample Types: Cell Culture Supernates
  369. HIF-1? Is an Essential Mediator of IFN-?-Dependent Immunity to Mycobacterium tuberculosis
    J Immunol, 2016-07-18;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  370. Cell death is not essential for caspase-1-mediated interleukin-1? activation and secretion
    Cell Death Differ, 2016-07-15;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  371. A Simple Screening Approach To Prioritize Genes for Functional Analysis Identifies a Role for Interferon Regulatory Factor 7 in the Control of Respiratory Syncytial Virus Disease
    Authors: John S Tregoning
    mSystems, 2016-06-28;1(3):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  372. Host Inflammatory Response to Mosquito Bites Enhances the Severity of Arbovirus Infection
    Authors: Marieke Pingen
    Immunity, 2016-06-21;44(6):1455-69.
    Species: Mouse
    Sample Types: Tissue Homogenates
  373. Plasminogen activator inhibitor-1 stimulates macrophage activation through Toll-like Receptor-4
    Authors: Kamlesh K Gupta
    Biochem Biophys Res Commun, 2016-06-15;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
  374. Sphingosine-1-Phosphate Receptor 2 Regulates Proinflammatory Cytokine Production and Osteoclastogenesis
    PLoS ONE, 2016-05-25;11(5):e0156303.
    Species: Mouse
    Sample Types: Cell Lysates
  375. Reducing hypoxia and inflammation during invasive pulmonary aspergillosis by targeting the Interleukin-1 receptor
    Sci Rep, 2016-05-24;6(0):26490.
    Species: Mouse
    Sample Types: Tissue Homogenates
  376. Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation
    J Clin Invest, 2016-05-23;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  377. Hemocyanins Stimulate Innate Immunity by Inducing Different Temporal Patterns of Proinflammatory Cytokine Expression in Macrophages
    J Immunol, 2016-04-22;196(11):4650-62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  378. A pharmacological inhibitor of NLRP3 inflammasome prevents non-alcoholic fatty liver disease in a mouse model induced by high fat diet
    Authors: G Yang, HE Lee, JY Lee
    Sci Rep, 2016-04-14;6(0):24399.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  379. Infection-Mediated Priming of Phagocytes Protects against Lethal Secondary Aspergillus fumigatus Challenge
    Authors: A Savers, O Rasid, M Parlato, M Brock, G Jouvion, B Ryffel, JM Cavaillon, G Eberl, O Ibrahim-Gr
    PLoS ONE, 2016-04-14;11(4):e0153829.
    Species: Mouse
    Sample Types: Tissue Homogenates
  380. Manipulation of Interleukin-1? and Interleukin-18 Production by Yersinia pestis Effectors YopJ and YopM and Redundant Impact on Virulence
    Authors: D Ratner, MP Orning, KK Starheim, R Marty-Roix, MK Proulx, JD Goguen, E Lien
    J. Biol. Chem., 2016-02-16;291(19):9894-905.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  381. C1P Attenuates Lipopolysaccharide-Induced Acute Lung Injury by Preventing NF-?B Activation in Neutrophils
    J Immunol, 2016-01-22;196(5):2319-26.
    Species: Mouse
    Sample Types: BALF
  382. Memory Th1 Cells Are Protective in Invasive Staphylococcus aureus Infection.
    Authors: Brown A, Murphy A, Lalor S, Leech J, O'Keeffe K, Mac Aogain M, O'Halloran D, Lacey K, Tavakol M, Hearnden C, Fitzgerald-Hughes D, Humphreys H, Fennell J, van Wamel W, Foster T, Geoghegan J, Lavelle E, Rogers T, McLoughlin R
    PLoS Pathog, 2015-11-05;11(11):e1005226.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  383. Effects of High-Intensity Swimming on Lung Inflammation and Oxidative Stress in a Murine Model of DEP-Induced Injury.
    Authors: Avila L, Bruggemann T, Bobinski F, da Silva M, Oliveira R, Martins D, Mazzardo-Martins L, Duarte M, de Souza L, Dafre A, Vieira R, Santos A, Bonorino K, Hizume Kunzler D
    PLoS ONE, 2015-09-02;10(9):e0137273.
    Species: Mouse
    Sample Types: Tissue Homogenates
  384. Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling.
    Authors: Wu Y, Wu Y, Mo S, Hsiao H, He Y, Lai M
    J Immunol, 2015-08-03;195(6):2612-23.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  385. The Inflammatory Caspases-1 and -11 Mediate the Pathogenesis of Dermatitis in Sharpin-Deficient Mice.
    Authors: Douglas T, Champagne C, Morizot A, Lapointe J, Saleh M
    J Immunol, 2015-07-27;195(5):2365-73.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  386. Deficient NLRP3 and AIM2 Inflammasome Function in Autoimmune NZB Mice.
    Authors: Sester D, Sagulenko V, Thygesen S, Cridland J, Loi Y, Cridland S, Masters S, Genske U, Hornung V, Andoniou C, Sweet M, Degli-Esposti M, Schroder K, Stacey K
    J Immunol, 2015-06-26;195(3):1233-41.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  387. An Allergic Lung Microenvironment Suppresses Carbon Nanotube-Induced Inflammasome Activation via STAT6-Dependent Inhibition of Caspase-1.
    Authors: Shipkowski K, Taylor A, Thompson E, Glista-Baker E, Sayers B, Messenger Z, Bauer R, Jaspers I, Bonner J
    PLoS ONE, 2015-06-19;10(6):e0128888.
    Species: Mouse
    Sample Types: BALF
  388. The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling.
    Authors: Fleming B, Chandrasekaran P, Dillon L, Dalby E, Suresh R, Sarkar A, El-Sayed N, Mosser D
    J Leukoc Biol, 2015-06-05;98(3):395-407.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  389. Endoplasmic reticulum stress-induced IRE1alpha activation mediates cross-talk of GSK-3beta and XBP-1 to regulate inflammatory cytokine production.
    Authors: Kim S, Joe Y, Kim H, Kim Y, Jeong S, Pae H, Ryter S, Surh Y, Chung H
    J Immunol, 2015-03-27;194(9):4498-506.
    Species: Mouse
    Sample Types: Serum
  390. Guanylate-binding proteins promote activation of the AIM2 inflammasome during infection with Francisella novicida.
    Authors: Meunier E, Wallet P, Dreier R, Costanzo S, Anton L, Ruhl S, Dussurgey S, Dick M, Kistner A, Rigard M, Degrandi D, Pfeffer K, Yamamoto M, Henry T, Broz P
    2015-03-16;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  391. A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
    Authors: Coll R, Robertson A, Chae J, Higgins S, Munoz-Planillo R, Inserra M, Vetter I, Dungan L, Monks B, Stutz A, Croker D, Butler M, Haneklaus M, Sutton C, Nunez G, Latz E, Kastner D, Mills K, Masters S, Schroder K, Cooper M, O'Neill L
    Nat Med, 2015-02-16;21(3):248-55.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  392. Liver X receptor-dependent inhibition of microglial nitric oxide synthase 2.
    Authors: Secor McVoy J, Oughli H, Oh U
    J Neuroinflammation, 2015-02-10;12(0):27.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  393. Necroptosis suppresses inflammation via termination of TNF- or LPS-induced cytokine and chemokine production.
    Authors: Kearney C, Cullen S, Tynan G, Henry C, Clancy D, Lavelle E, Martin S
    Cell Death Differ, 2015-01-23;22(8):1313-27.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  394. Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy.
    Authors: Jabir M, Hopkins L, Ritchie N, Ullah I, Bayes H, Li D, Tourlomousis P, Lupton A, Puleston D, Simon A, Bryant C, Evans T
    Autophagy, 2015-01-01;11(1):166-82.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  395. A critical role for the TLR signaling adapter Mal in alveolar macrophage-mediated protection against Bordetella pertussis.
    Authors: Bernard N, Finlay C, Tannahill G, Cassidy J, O'Neill L, Mills K
    Mucosal Immunol, 2014-12-17;8(5):982-92.
    Species: Mouse
    Sample Types: Tissue Homogenates
  396. Role of IL-1β in experimental cystic fibrosis upon P. aeruginosa infection.
    PLoS ONE, 2014-12-12;9(12):e114884.
    Species: Mouse
    Sample Types: Tissue Homogenates
  397. Dendritic cell IL-1alpha and IL-1beta are polyubiquitinated and degraded by the proteasome.
    Authors: Ainscough J, Frank Gerberick G, Zahedi-Nejad M, Lopez-Castejon G, Brough D, Kimber I, Dearman R
    J Biol Chem, 2014-11-04;289(51):35582-92.
    Species: Mouse
    Sample Types: Cell Lysates
  398. No Impairment in host defense against Streptococcus pneumoniae in obese CPEfat/fat mice.
    Authors: Mancuso P, O Brien E, Prano J, Goel D, Aronoff D
    PLoS ONE, 2014-09-09;9(9):e106420.
    Species: Mouse
    Sample Types: Serum
  399. Murine lung injury caused by Leptospira interrogans glycolipoprotein, a specific Na/K-ATPase inhibitor.
    Authors: Goncalves-de-Albuquerque C, Burth P, Silva A, de Moraes I, Oliveira F, Santelli R, Freire A, de Lima G, da Silva E, da Silva C, Morandi V, Bozza P, Younes-Ibrahim M, de Castro Faria Neto H, de Castro Faria M
    Respir Res, 2014-08-14;15(0):93.
    Species: Mouse
    Sample Types: BALF
  400. Micheliolide, a new sesquiterpene lactone that inhibits intestinal inflammation and colitis-associated cancer.
    Authors: Viennois E, Xiao B, Ayyadurai S, Wang L, Wang P, Zhang Q, Chen Y, Merlin D
    Lab Invest, 2014-07-28;94(9):950-65.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  401. Role of lysosomes in silica-induced inflammasome activation and inflammation in absence of MARCO.
    Authors: Biswas R, Hamilton R, Holian A
    J Immunol Res, 2014-06-26;2014(0):304180.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  402. Palmitoylethanolamide stimulates phagocytosis of Escherichia coli K1 by macrophages and increases the resistance of mice against infections.
    Authors: Redlich S, Ribes S, Schutze S, Nau R
    J Neuroinflammation, 2014-06-14;11(0):108.
    Species: Mouse
    Sample Types: Tissue Homogenates
  403. Role of the aryl hydrocarbon receptor in the immune response profile and development of pathology during Plasmodium berghei Anka infection.
    Authors: Brant F, Miranda A, Esper L, Rodrigues D, Kangussu L, Bonaventura D, Soriani F, Pinho V, Souza D, Rachid M, Weiss L, Tanowitz H, Teixeira M, Teixeira A, Machado F
    Infect Immun, 2014-05-12;82(8):3127-40.
    Species: Mouse
    Sample Types: Tissue Homogenates
  404. Heat shock protein 60: an endogenous inducer of dopaminergic cell death in Parkinson disease.
    Authors: Noelker C, Morel L, Osterloh A, Alvarez-Fischer D, Lescot T, Breloer M, Gold M, Oertel W, Henze C, Michel P, Dodel R, Lu L, Hirsch E, Hunot S, Hartmann A
    J Neuroinflammation, 2014-05-08;11(0):86.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  405. The effect of size on Ag nanosphere toxicity in macrophage cell models and lung epithelial cell lines is dependent on particle dissolution.
    Authors: Hamilton, Raymond, Buckingham, Sarah, Holian, Andrij
    Int J Mol Sci, 2014-04-22;15(4):6815-30.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  406. Peripheral inflammation is associated with remote global gene expression changes in the brain.
    Authors: Thomson, Carolyn, McColl, Alison, Cavanagh, Jonathan, Graham, Gerard J
    J Neuroinflammation, 2014-04-08;11(0):73.
    Species: Mouse
    Sample Types: Plasma
  407. Staphylococcus aureus infection of mice expands a population of memory gammadelta T cells that are protective against subsequent infection.
    Authors: Murphy A, O'Keeffe K, Lalor S, Maher B, Mills K, McLoughlin R
    J Immunol, 2014-03-12;192(8):3697-708.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  408. ASC in renal collecting duct epithelial cells contributes to inflammation and injury after unilateral ureteral obstruction.
    Authors: Komada T, Usui F, Shirasuna K, Kawashima A, Kimura H, Karasawa T, Nishimura S, Sagara J, Noda T, Taniguchi S, Muto S, Nagata D, Kusano E, Takahashi M
    Am J Pathol, 2014-03-05;184(5):1287-98.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  409. Toll-like receptor 9 deficiency protects mice against Pseudomonas aeruginosa lung infection.
    Authors: Benmohamed F, Medina M, Wu Y, Maschalidi S, Jouvion G, Guillemot L, Chignard M, Manoury B, Touqui L
    PLoS ONE, 2014-03-04;9(3):e90466.
    Species: Mouse
    Sample Types: BALF
  410. Lipopolysaccharide induces inflammatory hyperalgesia triggering a TLR4/MyD88-dependent cytokine cascade in the mice paw.
    Authors: Calil I, Zarpelon A, Guerrero A, Alves-Filho J, Ferreira S, Cunha F, Cunha T, Verri W
    PLoS ONE, 2014-03-03;9(3):e90013.
    Species: Mouse
    Sample Types: Tissue Homogenates
  411. The role of Nox2-derived ROS in the development of cognitive impairment after sepsis.
    Authors: Hernandes M, D'Avila J, Trevelin S, Reis P, Kinjo E, Lopes L, Castro-Faria-Neto H, Cunha F, Britto L, Bozza F
    J Neuroinflammation, 2014-02-27;11(0):36.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  412. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
    Authors: Tatano Y, Shimizu T, Tomioka H
    Sci Rep, 2014-02-20;4(0):4146.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  413. Lysosomes integrate metabolic-inflammatory cross-talk in primary macrophage inflammasome activation.
    Authors: Weber K, Schilling J
    J Biol Chem, 2014-02-15;289(13):9158-71.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  414. MyD88 signalling in myeloid cells is sufficient to prevent chronic mycobacterial infection.
    Authors: Berod L, Stuve P, Swallow M, Arnold-Schrauf C, Kruse F, Gentilini M, Freitag J, Holzmann B, Sparwasser T
    Eur J Immunol, 2014-02-13;44(5):1399-409.
    Species: Mouse
    Sample Types: Serum
  415. PPAR-gamma/IL-10 axis inhibits MyD88 expression and ameliorates murine polymicrobial sepsis.
    Authors: Ferreira A, Sisti F, Sonego F, Wang S, Filgueiras L, Brandt S, Serezani A, Du H, Cunha F, Alves-Filho J, Serezani C
    J Immunol, 2014-01-31;192(5):2357-65.
    Species: Mouse
    Sample Types: Serum
  416. Protective or deleterious role of scavenger receptors SR-A and CD36 on host resistance to Staphylococcus aureus depends on the site of infection.
    Authors: Blanchet C, Jouvion G, Fitting C, Cavaillon J, Adib-Conquy M
    PLoS ONE, 2014-01-31;9(1):e87927.
    Species: Mouse
    Sample Types: Plasma
  417. Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
    Authors: Ataide M, Andrade W, Zamboni D, Wang D, Souza M, Franklin B, Elian S, Martins F, Pereira D, Reed G, Fitzgerald K, Golenbock D, Gazzinelli R
    PLoS Pathog, 2014-01-16;10(1):e1003885.
    Species: Mouse
    Sample Types: Whole Blood
  418. Promyelocytic leukemia protein interacts with the apoptosis-associated speck-like protein to limit inflammasome activation.
    Authors: Dowling J, Becker C, Bourke N, Corr S, Connolly D, Quinn S, Pandolfi P, Mansell A, O'Neill L
    J Biol Chem, 2014-01-09;289(10):6429-37.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  419. Sustained Na+/H+ exchanger activation promotes gliotransmitter release from reactive hippocampal astrocytes following oxygen-glucose deprivation.
    Authors: Cengiz P, Kintner D, Chanana V, Yuan H, Akture E, Kendigelen P, Begum G, Fidan E, Uluc K, Ferrazzano P, Sun D
    PLoS ONE, 2014-01-02;9(1):e84294.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  420. IL-25 and type 2 innate lymphoid cells induce pulmonary fibrosis.
    Authors: Hams, Emily, Armstrong, Michelle, Barlow, Jillian, Saunders, Sean P, Schwartz, Christia, Cooke, Gordon, Fahy, Ruairi J, Crotty, Thomas B, Hirani, Nikhil, Flynn, Robin J, Voehringer, David, McKenzie, Andrew N, Donnelly, Seamas C, Fallon, Padraic
    Proc Natl Acad Sci U S A, 2013-12-16;111(1):367-72.
    Species: Mouse
    Sample Types: Tissue Homogenates
  421. A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages.
    Authors: Gonzalez Y, Doens D, Santamaria R, Ramos M, Restrepo C, Barros de Arruda L, Lleonart R, Gutierrez M, Fernandez P
    PLoS ONE, 2013-12-16;8(12):e84107.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  422. Lack of platelet-activating factor receptor protects mice against diet-induced adipose inflammation and insulin-resistance despite fat pad expansion.
    Authors: Menezes-Garcia Z, Oliveira M, Lima R, Soriani F, Cisalpino D, Botion L, Teixeira M, Souza D, Ferreira A
    Obesity (Silver Spring), 2013-12-14;22(3):663-72.
    Species: Mouse
    Sample Types: Tissue Homogenates
  423. NLRP3 inflammasome activation by Paracoccidioides brasiliensis.
    Authors: Tavares A, Magalhaes K, Almeida R, Correa R, Burgel P, Bocca A
    PLoS Negl Trop Dis, 2013-12-05;7(12):e2595.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  424. Rift Valley fever virus infection induces activation of the NLRP3 inflammasome.
    Authors: Ermler M, Traylor Z, Patel K, Schattgen S, Vanaja S, Fitzgerald K, Hise A
    Virology, 2013-12-03;449(0):174-80.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  425. Defining the range of pathogens susceptible to Ifitm3 restriction using a knockout mouse model.
    Authors: Everitt, Aaron R, Clare, Simon, McDonald, Jacqueli, Kane, Leanne, Harcourt, Katherin, Ahras, Malika, Lall, Amar, Hale, Christin, Rodgers, Angela, Young, Douglas, Haque, Ashraful, Billker, Oliver, Tregoning, John S, Dougan, Gordon, Kellam, Paul
    PLoS ONE, 2013-11-21;8(11):e80723.
    Species: Mouse
    Sample Types: BALF
  426. The lung inflammation and skeletal muscle wasting induced by subchronic cigarette smoke exposure are not altered by a high-fat diet in mice.
    Authors: Hansen, Michelle, Chen, Hui, Jones, Jessica, Langenbach, Shenna Y, Vlahos, Ross, Gualano, Rosa C, Morris, Margaret, Anderson, Gary P
    PLoS ONE, 2013-11-19;8(11):e80471.
    Species: Mouse
    Sample Types: Tissue Homogenates
  427. A2B adenosine receptors prevent insulin resistance by inhibiting adipose tissue inflammation via maintaining alternative macrophage activation.
    Authors: Csoka B, Koscso B, Toro G, Kokai E, Virag L, Nemeth Z, Pacher P, Bai P, Hasko G
    Diabetes, 2013-11-05;63(3):850-66.
    Species: Mouse
    Sample Types: Plasma
  428. Further evidence for an anti-inflammatory role of artesunate in experimental cerebral malaria.
    Authors: Miranda A, Brant F, Rocha N, Cisalpino D, Rodrigues D, Souza D, Machado F, Rachid M, Teixeira A, Campos A
    Malar J, 2013-11-02;12(0):388.
    Species: Mouse
    Sample Types: Tissue Homogenates
  429. TXNIP deficiency exacerbates endotoxic shock via the induction of excessive nitric oxide synthesis.
    Authors: Park Y, Yoon S, Suh H, Kim D, Park J, Jung H, Kim T, Yoon S, Min J, Na H, Lee S, Lee H, Lee Y, Lee H, Choi I
    PLoS Pathog, 2013-10-03;9(10):e1003646.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  430. Mesenchymal stem cells inhibit cutaneous radiation-induced fibrosis by suppressing chronic inflammation.
    Authors: Horton J, Hudak K, Chung E, White A, Scroggins B, Burkeen J, Citrin D
    Stem Cells, 2013-10-01;31(10):2231-41.
    Species: Mouse
    Sample Types: Tissue Homogenates
  431. Bee venom and its component apamin as neuroprotective agents in a Parkinson disease mouse model.
    Authors: Alvarez-Fischer D, Noelker C, Vulinovic F, Grunewald A, Chevarin C, Klein C, Oertel W, Hirsch E, Michel P, Hartmann A
    PLoS ONE, 2013-04-18;8(4):e61700.
    Species: Mouse
    Sample Types: Tissue Homogenates
  432. Intestinal CCL11 and eosinophilic inflammation is regulated by myeloid cell-specific RelA/p65 in mice.
    Authors: Waddell A, Ahrens R, Tsai Y, Sherrill J, Denson L, Steinbrecher K, Hogan S
    J Immunol, 2013-04-05;190(9):4773-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  433. A novel murine model of rhinoscleroma identifies Mikulicz cells, the disease signature, as IL-10 dependent derivatives of inflammatory monocytes.
    Authors: Fevre C, Almeida A, Taront S, Pedron T, Huerre M, Prevost M, Kieusseian A, Cumano A, Brisse S, Sansonetti P, Tournebize R
    EMBO Mol Med, 2013-04-01;5(4):516-30.
    Species: Mouse
    Sample Types: Tissue Homogenates
  434. Ghrelin inhibits LPS-induced release of IL-6 from mouse dopaminergic neurones.
    Authors: Beynon A, Brown M, Wright R, Rees M, Sheldon I, Davies J
    J Neuroinflammation, 2013-03-19;10(0):40.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  435. TLR2 deletion promotes arthritis through reduction of IL-10.
    Authors: Huang Q, Koessler R, Birkett R, Perlman H, Xing L, Pope R
    J Leukoc Biol, 2013-02-27;93(5):751-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  436. Milano summer particulate matter (PM10) triggers lung inflammation and extra pulmonary adverse events in mice.
    Authors: Farina F, Sancini G, Battaglia C, Tinaglia V, Mantecca P, Camatini M, Palestini P
    PLoS ONE, 2013-02-25;8(2):e56636.
    Species: Mouse
    Sample Types: BALF
  437. Intravenous mesenchymal stem cells prevented rejection of allogeneic corneal transplants by aborting the early inflammatory response.
    Authors: Oh J, Lee R, Yu J, Ko J, Lee H, Ko A, Roddy G, Prockop D
    Mol Ther, 2012-08-28;20(11):2143-52.
    Species: Mouse
    Sample Types: Tissue Homogenates
  438. Macrophage Dectin-1 Expression Is Controlled by Leukotriene B4 via a GM-CSF/PU.1 Axis.
    Authors: Serezani CH, Kane S, Collins L
    J. Immunol., 2012-06-13;189(2):906-15.
    Species: Mouse
    Sample Types: BALF
  439. Dok2 mediates the CD200Fc attenuation of Abeta-induced changes in glia.
    Authors: Lyons A, Downer E, Costello D, Murphy N, Lynch M
    J Neuroinflammation, 2012-05-29;9(0):107.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  440. Influence of hypoxia-inducible factor 1-alpha on dendritic cell differentiation and migration.
    Authors: Kohler T, Reizis B, Johnson RS, Weighardt H, Forster I
    Eur. J. Immunol., 2012-05-01;42(5):1226-36.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  441. TLR9 and MyD88 are crucial for the development of protective immunity to malaria.
    Authors: Gowda NM, Wu X, Gowda DC
    J. Immunol., 2012-04-18;188(10):5073-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  442. Interleukin-1 participates in the classical and alternative activation of microglia/macrophages after spinal cord injury.
    Authors: Sato A, Ohtaki H, Tsumuraya T, Song D, Ohara K, Asano M, Iwakura Y, Atsumi T, Shioda S
    J Neuroinflammation, 2012-04-07;9(0):65.
    Species: Mouse
    Sample Types: Tissue Homogenates
  443. Role of Toll interleukin-1 receptor (IL-1R) 8, a negative regulator of IL-1R/Toll-like receptor signaling, in resistance to acute Pseudomonas aeruginosa lung infection.
    Authors: Veliz Rodriguez T, Moalli F, Polentarutti N, Paroni M, Bonavita E, Anselmo A, Nebuloni M, Mantero S, Jaillon S, Bragonzi A, Mantovani A, Riva F, Garlanda C
    Infect. Immun., 2011-10-24;80(1):100-9.
    Species: Mouse
    Sample Types: Serum
  444. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
    Authors: El-Behi M, Ciric B, Dai H
    Nat. Immunol., 2011-04-24;12(6):568-75.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  445. The Therapeutic Potential of the Humoral Pattern Recognition Molecule PTX3 in Chronic Lung Infection Caused by Pseudomonas aeruginosa.
    Authors: Moalli F, Paroni M, Veliz Rodriguez T, Riva F, Polentarutti N, Bottazzi B, Valentino S, Mantero S, Nebuloni M, Mantovani A, Bragonzi A, Garlanda C
    J. Immunol., 2011-03-25;186(9):5425-34.
    Species: Mouse
    Sample Types: Tissue Homogenates
  446. IL-27 mediates the response to IFN-beta therapy in multiple sclerosis patients by inhibiting Th17 cells.
    Authors: Sweeney CM, Lonergan R, Basdeo SA, Kinsella K, Dungan LS, Higgins SC, Kelly PJ, Costelloe L, Tubridy N, Mills KH, Fletcher JM
    Brain Behav. Immun., 2011-03-21;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  447. CD4 T cells promote rather than control tuberculosis in the absence of PD-1-mediated inhibition.
    Authors: Barber DL, Mayer-Barber KD, Feng CG
    J. Immunol., 2010-12-20;186(3):1598-607.
    Species: Mouse
    Sample Types: BALF
  448. A critical role for C5L2 in the pathogenesis of experimental allergic asthma.
    Authors: Zhang X, Schmudde I, Laumonnier Y, Pandey MK, Clark JR, Konig P, Gerard NP, Gerard C, Wills-Karp M, Kohl J
    J. Immunol., 2010-10-25;185(11):6741-52.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  449. Toll-like receptor 4 mediates the response of epithelial and stromal cells to lipopolysaccharide in the endometrium.
    Authors: Sheldon IM, Roberts MH
    PLoS ONE, 2010-09-22;5(9):e12906.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  450. Tyrosine kinase 2 controls IL-1beta production at the translational level.
    Authors: Radwan M, Stiefvater R, Grunert T, Sharif O, Miller I, Marchetti-Deschmann M, Allmaier G, Gemeiner M, Knapp S, Kovarik P, Muller M, Strobl B
    J. Immunol., 2010-08-16;185(6):3544-53.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  451. Importance of TLR2 in the direct response of T lymphocytes to Schistosoma mansoni antigens.
    Authors: Burton OT, Gibbs S, Miller N, Jones FM, Wen L, Dunne DW, Cooke A, Zaccone P
    Eur. J. Immunol., 2010-08-01;40(8):2221-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  452. Distinct roles of hepatocyte- and myeloid cell-derived IL-1 receptor antagonist during endotoxemia and sterile inflammation in mice.
    Authors: Lamacchia C, Palmer G, Bischoff L, Rodriguez E, Talabot-Ayer D, Gabay C
    J. Immunol., 2010-07-16;185(0):2516-24.
    Species: Mouse
    Sample Types: Serum
  453. P2X(7) receptor-mediated release of cathepsins from macrophages is a cytokine-independent mechanism potentially involved in joint diseases.
    Authors: Lopez-Castejon G, Theaker J, Pelegrin P
    J. Immunol., 2010-07-16;185(4):2611-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  454. Metabolic syndrome and altered gut microbiota in mice lacking Toll-like receptor 5.
    Authors: Vijay-Kumar M, Aitken JD, Carvalho FA, Cullender TC, Mwangi S, Srinivasan S, Sitaraman SV, Knight R, Ley RE, Gewirtz AT
    Science, 2010-03-04;328(5975):228-31.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  455. Th17 cells are the dominant T cell subtype primed by Shigella flexneri mediating protective immunity.
    Authors: Sellge G, Magalhaes JG, Konradt C, Fritz JH, Salgado-Pabon W, Eberl G, Bandeira A, Di Santo JP, Sansonetti PJ, Phalipon A
    J. Immunol., 2010-01-20;184(4):2076-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  456. IL-1R1/MyD88 signaling is critical for elastase-induced lung inflammation and emphysema.
    Authors: Couillin I, Vasseur V, Charron S, Gasse P, Tavernier M, Guillet J, Lagente V, Fick L, Jacobs M, Coelho FR, Moser R, Ryffel B
    J. Immunol., 2009-12-15;183(12):8195-202.
    Species: Mouse
    Sample Types: BALF
  457. A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4.
    Authors: Reynolds CM, Draper E, Keogh B, Rahman A, Moloney AP, Mills KH, Loscher CE, Roche HM
    J. Nutr., 2009-10-21;139(12):2351-7.
    Species: Mouse
    Sample Types: Serum
  458. E-prostanoid 3 receptor deletion improves pulmonary host defense and protects mice from death in severe Streptococcus pneumoniae infection.
    Authors: Aronoff DM, Lewis C, Serezani CH, Eaton KA, Goel D, Phipps JC, Peters-Golden M, Mancuso P
    J. Immunol., 2009-07-27;183(4):2642-9.
    Species: Mouse
    Sample Types: BALF
  459. TREM-1 activation alters the dynamics of pulmonary IRAK-M expression in vivo and improves host defense during pneumococcal pneumonia.
    Authors: Lagler H, Sharif O, Haslinger I, Matt U, Stich K, Furtner T, Doninger B, Schmid K, Gattringer R, de Vos AF, Knapp S
    J. Immunol., 2009-07-13;183(3):2027-36.
    Species: Mouse
    Sample Types: Tissue Homogenates
  460. The CDK domain of p21 is a suppressor of IL-1beta-mediated inflammation in activated macrophages.
    Authors: Scatizzi JC, Mavers M, Hutcheson J, Young B, Shi B, Pope RM, Ruderman EM, Samways DS, Corbett JA, Egan TM, Perlman H
    Eur. J. Immunol., 2009-03-01;39(3):820-5.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  461. Serotonin and angiotensin receptors in cardiac fibroblasts coregulate adrenergic-dependent cardiac hypertrophy.
    Authors: Jaffre F, Bonnin P, Callebert J, Debbabi H, Setola V, Doly S, Monassier L, Mettauer B, Blaxall BC, Launay JM, Maroteaux L
    Circ. Res., 2008-11-20;104(1):113-23.
    Species: Mouse
    Sample Types: Plasma
  462. Identification of cardiac troponin I sequence motifs leading to heart failure by induction of myocardial inflammation and fibrosis.
    Authors: Kaya Z, Goser S, Buss SJ, Leuschner F, Ottl R, Li J, Volkers M, Zittrich S, Pfitzer G, Rose NR, Katus HA
    Circulation, 2008-10-27;118(20):2063-72.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  463. Mutual modulation between interleukin-10 and interleukin-6 induced by Rhodococcus aurantiacus infection in mice.
    Authors: Yimin, Kohanawa M, Ozaki M, Haga S, Fujikawa K, Zhao S, Kuge Y, Tamaki N
    Microbes Infect., 2008-09-13;10(14):1450-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  464. Divergent effects of hypoxia on dendritic cell functions.
    Authors: Mancino A, Schioppa T, Larghi P, Pasqualini F, Nebuloni M, Chen IH, Sozzani S, Austyn JM, Mantovani A, Sica A
    Blood, 2008-08-11;112(9):3723-34.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  465. Induction of IL-33 expression and activity in central nervous system glia.
    Authors: Hudson CA, Christophi GP, Gruber RC, Wilmore JR, Lawrence DA, Massa PT
    J. Leukoc. Biol., 2008-06-13;84(3):631-43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  466. Lack of Toll IL-1R8 exacerbates Th17 cell responses in fungal infection.
    Authors: Bozza S, Zelante T, Moretti S, Bonifazi P, DeLuca A, D'Angelo C, Giovannini G, Garlanda C, Boon L, Bistoni F, Puccetti P, Mantovani A, Romani L
    J. Immunol., 2008-03-15;180(6):4022-31.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  467. Cigarette smoke-induced pulmonary inflammation is TLR4/MyD88 and IL-1R1/MyD88 signaling dependent.
    Authors: Doz E, Noulin N, Boichot E, Guenon I, Fick L, Le Bert M, Lagente V, Ryffel B, Schnyder B, Quesniaux VF, Couillin I
    J. Immunol., 2008-01-15;180(2):1169-78.
    Species: Mouse
    Sample Types: Tissue Homogenates
  468. Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
    Authors: Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Herve C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, Garcia de Frutos P, Dahlback B, Carmeliet P, Hoylaerts MF, Moons L
    Blood, 2007-12-21;111(8):4096-105.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  469. Deletion of TLR5 results in spontaneous colitis in mice.
    Authors: Vijay-Kumar M, Sanders CJ, Taylor RT, Kumar A, Aitken JD, Sitaraman SV, Neish AS, Uematsu S, Akira S, Williams IR, Gewirtz AT
    J. Clin. Invest., 2007-12-01;117(12):3909-21.
    Species: Mouse
    Sample Types: Serum
  470. IL-1R1/MyD88 signaling and the inflammasome are essential in pulmonary inflammation and fibrosis in mice.
    Authors: Gasse P, Mary C, Guenon I, Noulin N, Charron S, Schnyder-Candrian S, Schnyder B, Akira S, Quesniaux VF, Lagente V, Ryffel B, Couillin I
    J. Clin. Invest., 2007-12-01;117(12):3786-99.
    Species: Mouse
    Sample Types: BALF
  471. Involvement of vitronectin in lipopolysaccaride-induced acute lung injury.
    Authors: Tsuruta Y, Park YJ, Siegal GP, Liu G, Abraham E
    J. Immunol., 2007-11-15;179(10):7079-86.
    Species: Mouse
    Sample Types: Tissue Homogenates
  472. CD40L disruption enhances Abeta vaccine-mediated reduction of cerebral amyloidosis while minimizing cerebral amyloid angiopathy and inflammation.
    Authors: Obregon D, Hou H, Bai Y, Nikolic WV, Mori T, Luo D, Zeng J, Ehrhart J, Fernandez F, Morgan D, Giunta B, Town T, Tan J
    Neurobiol. Dis., 2007-10-16;29(2):336-53.
    Species: Mouse
    Sample Types: Plasma
  473. Differential ex vivo nitric oxide production by acutely isolated neonatal and adult microglia.
    Authors: Schell JB, Crane CA, Smith MF, Roberts MR
    J. Neuroimmunol., 2007-08-15;189(1):75-87.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  474. Lactoferrin enhanced efficacy of the BCG vaccine to generate host protective responses against challenge with virulent Mycobacterium tuberculosis.
    Authors: Hwang SA, Wilk KM, Budnicka M, Olsen M, Bangale YA, Hunter RL, Kruzel ML, Actor JK
    Vaccine, 2007-07-27;25(37):6730-43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  475. ABCC transporter inhibition reduces zymosan-induced peritonitis.
    Authors: Leite DF, Echevarria-Lima J, Ferreira SC, Calixto JB, Rumjanek VM
    J. Leukoc. Biol., 2007-06-18;82(3):630-7.
    Species: Mouse
    Sample Types: Tissue Secretion
  476. Neurokinin-1 receptor antagonist treatment protects mice against lung injury in polymicrobial sepsis.
    Authors: Hegde A, Zhang H, Moochhala SM, Bhatia M
    J. Leukoc. Biol., 2007-06-12;82(3):678-85.
    Species: Mouse
    Sample Types: Plasma
  477. Nod1-mediated innate immune recognition of peptidoglycan contributes to the onset of adaptive immunity.
    Authors: Fritz JH, Le Bourhis L, Sellge G, Magalhaes JG, Fsihi H, Kufer TA, Collins C, Viala J, Ferrero RL, Girardin SE, Philpott DJ
    Immunity, 2007-04-12;26(4):445-59.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  478. Glucose-6-phosphate dehydrogenase deficiency and the inflammatory response to endotoxin and polymicrobial sepsis.
    Authors: Wilmanski J, Villanueva E, Deitch EA, Spolarics Z
    Crit. Care Med., 2007-02-01;35(2):510-8.
    Species: Mouse
    Sample Types: Plasma
  479. TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
    Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
    J. Immunol., 2006-12-01;177(11):7980-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  480. Engagement of CD14 mediates the inflammatory potential of monosodium urate crystals.
    Authors: Scott P, Ma H, Viriyakosol S, Terkeltaub R, Liu-Bryan R
    J. Immunol., 2006-11-01;177(9):6370-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  481. Anti-tumor necrosis factor alpha F(ab')2 antibody fragments protect in murine polymicrobial sepsis: concentration and early intervention are fundamental to the outcome.
    Authors: Marquez-Velasco R, Bojalil R, Buelna A, Flores-Guzman F, Estevez-Ramirez J, Laguna J, Hernandez AM, Diaz-Quinonez A, Paniagua-Solis JF
    Inflamm. Res., 2006-09-01;55(9):378-84.
    Species: Mouse
    Sample Types: Serum
  482. Choosing the frequency of deep inflation in mice: balancing recruitment against ventilator-induced lung injury.
    Authors: Allen GB, Suratt BT, Rinaldi L, Petty JM, Bates JH
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006-05-12;291(4):L710-7.
    Species: Mouse
    Sample Types: BALF, Tissue Homogenates
  483. The effects of dehydroepiandrosterone (DHEA) on in vitro spleen cell proliferation and cytokine production.
    Authors: Powell JM, Sonnenfeld G
    J. Interferon Cytokine Res., 2006-01-01;26(1):34-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  484. An essential role for non-bone marrow-derived cells in control of Pseudomonas aeruginosa pneumonia.
    Authors: Hajjar AM, Harowicz H, Liggitt HD, Fink PJ, Wilson CB, Skerrett SJ
    Am. J. Respir. Cell Mol. Biol., 2005-08-11;33(5):470-5.
    Species: Mouse
    Sample Types: Tissue Homogenates
  485. Anti-inflammatory activity in the aqueous crude extract of the leaves of Nidularium procerum: A bromeliaceae from the Brazilian coastal rain forest.
    Authors: Amendoeira FC, Frutuoso VS, Zanon C, Chedier LM, Figueiredo MR, Kaplan MA, Bandeira-Melo C, Bozza PT, Castro-Faria-Neto HC
    Biol. Pharm. Bull., 2005-06-01;28(6):1010-5.
    Species: Mouse
    Sample Types: Pleural Fluid
  486. Attenuation of primary nonfunction for syngeneic islet graft using sodium 4-phenylbutyrate.
    Authors: Fu SH, Chen ST, Hsu BR
    Transplant. Proc., 2005-05-01;37(4):1830-1.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  487. Active hexose correlated compound enhances the immune function of mice in the hindlimb-unloading model of spaceflight conditions.
    Authors: Aviles H, Belay T, Vance M, Sun B, Sonnenfeld G
    J. Appl. Physiol., 2004-06-11;97(4):1437-44.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  488. Toll-like receptor 2 (TLR2) mediates astrocyte activation in response to the Gram-positive bacterium Staphylococcus aureus.
    Authors: Esen N, Tanga FY, DeLeo JA, Kielian T
    J. Neurochem., 2004-02-01;88(3):746-58.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  489. Membrane-bound Interleukin-1 alpha mediates leukocyte adhesion during atherogenesis
    Species: Mouse
    Sample Types: Serum

FAQs

  1. Does the Mouse IL-1 beta/IL-1F2 DuoSet ELISA (Catalog DY401) crosss-react with the pro-form of Mouse IL-1 beta?

    • The Mouse IL-1 beta/IL-1F2 DuoSet ELISA is designed to detect mature mouse IL-1 beta and the assay is calibrated against the mature form of mouse IL-1 beta. It is possible that the kit also detects the pro-form, however, R&D Systems has not performed this characterization.

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Reviews for Mouse IL-1 beta/IL-1F2 DuoSet ELISA

Average Rating: 4.7 (Based on 34 Reviews)

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Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 10/05/2023
Sample Tested: primary mouse fibroblast
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 06/23/2023
Sample Tested: Mouse spleenocytes,Mouse splenocytes
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 05/19/2023
Sample Tested: Colon tissue,Serum
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Samadhan Kshirsagar on 05/04/2023
Sample Tested: Serum
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 02/07/2023
Sample Tested: Mouse spleenocytes
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 09/09/2022
Sample Tested: PMBC
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/15/2022
Sample Tested: BAL fluid
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 05/24/2022
Sample Tested: whole blood supernatant
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 03/03/2022
Sample Tested: J774A.1 mouse reticulum cell sarcoma macrophage cell line

Optimisation of cytokine response and cell numbers

Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 03/01/2022
Sample Tested: Cell Lysates
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 02/28/2022
Sample Tested: BMDM supernates,Cell Culture Supernates,J774A.1 mouse reticulum cell sarcoma macrophage cell line

Except for the highest standard all other standards worked well

Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/13/2021
Sample Tested: serum and cell supernatant

we have used this kit for LPS stimulated in vivo and in vitro experiments. It works very well and efficiently.

Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/06/2021
Sample Tested: Tissue Lysates
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Martin Torres on 09/23/2021
Sample Tested: Mice serum

Mouse IL-1b ELISA kit was used to assess IL-1b levels in serum after 12-weeks treatment of adult C57BL7/6J mice with a high-fat diet treatment. Results were accurate and showed low intra-experimental variation (less than 6 %). The picture shows the standard diet (SD), high-fat diet (HFD), and two concentrations of corn pericarp extract (200 and 500 parts per million of extract).

Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 12/11/2020
Sample Tested: Human cell conditioned medium
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Mustafa Girnary on 10/20/2020
Sample Tested: THP-1 human acute monocytic leukemia cell line
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 11/10/2019
Sample Tested: Cell culture supernatant,RAW 264.7 mouse monocyte/macrophage cell line
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 09/11/2019
Sample Tested: mouse macrophages
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Wen Li on 08/06/2019
Sample Tested: Bone marrow-derived dendritic cells
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 05/20/2019
Sample Tested: Adult lung
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Ivan Luzardo on 12/11/2018
Sample Tested: Serum and Plasma
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Alejandra Palomino Antolín on 07/27/2018
Sample Tested: Brain (glial cell in hippocampus)
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/17/2018
Sample Tested: J774A.1 mouse reticulum cell sarcoma macrophage cell line
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/13/2018
Sample Tested: Cell culture supernatant
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Ella Zeldich on 11/22/2017
Sample Tested: mouse primary microglia cells

We needed to calibrate the dilutions of our samples.

Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 09/27/2017
Sample Tested: Peritoneal resident macrophages
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/21/2017
Sample Tested: Brain tissue
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 05/24/2017
Sample Tested: Plasma
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 05/22/2017
Sample Tested: Whole blood
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 04/19/2017
Sample Tested: Lung tissue
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Anonymous on 07/05/2016
Sample Tested: Mouse plasma samples
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA
By Ariela Haimovich on 05/24/2016
Sample Tested: BMDC cells stimulated with LPS for 4 hrs,Bone marrow-derived dendritic cells
Mouse IL-1 beta/IL-1F2 DuoSet ELISA DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate
By Jacqueline Kimmey on 04/05/2016
Sample Tested: murine lung homogenate supernatant

lungs were homogenized in PBS-T, and sup was filtered through 0.22um filter before use. Homogenate was diluted 1:3 for analysis by ELISA.

Mouse IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate DY401
Mouse IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate
By Anonymous on 10/26/2015
Sample Tested: Purified mouse IL-1beta protein

50ul of murine IL-1beta Capture antibody (4ug/mL) was coated per well of a 96 well plate at 4 degrees overnight. Purified IL-1beta standard was diluted (7 fold) and assayed to ensure the quality of the ELISA. Mouse IL-1beta Detector antibody was added (2h @ RT) followed by a 20 min incubation with Streptavidin-HRP. Substrate solution was added to measure IL-1beta concentration according to the manufactures protocol. The standard curve looked great as can be seen by calculation of the R- squared value. Highly recommend doing ELISA's using kits from R&D.
Buffer: 7-point standard curve

Mouse IL-1 beta/IL-1F2 DuoSet ELISA, 15 Plate DY401