Home / IFN-alpha / Mouse IFN-alpha Fluorescein MAb (Clone RMMA-1)

Mouse IFN-alpha Fluorescein MAb (Clone RMMA-1)

Catalog #: 22100-3
5 Citations Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
22100-3
Product Details
Citations (5)
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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse IFN-alpha Fluorescein MAb (Clone RMMA-1) Summary

Species Reactivity
Mouse
Source
Monoclonal Rat IgG1 Clone # RMMA-1
Formulation
Phosphate buffered saline (PBS) containing 1% BSA and 0.05% Kathon, pH 7.2
Label
Fluorescein (Excitation= 488 nm, Emission= 515-545 nm)

Applications

Recommended Concentration
Sample
Flow Cytometry
Please refer to the PDF datasheet for specifications.
Immunohistochemistry
Please refer to the PDF datasheet for specifications.

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Shipping
The product is shipped with polar packs. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IFN-alpha

Interferon-alpha (IFN-alpha), also known as leukocyte interferon, represents a group of related but distinct proteins that share over 95% amino acid sequence homology. They are members of the type I interferon family which share a common cell surface receptor composed of two subunits, a 100 kDa ligand-binding subunit (IFN-alpha R2) and a 125 kDa ligand binding and signal transduction subunit (IFN-alpha R1) that is involved both in ligand binding and signal transduction. IFN-alpha has both anti-viral and immunomodulatory activities on target cells.

Long Name
Interferon alpha
Entrez Gene IDs
3440 (Human)
Alternate Names
IFNA; IFNA2; IFNA2b; IFNalpha; IFN-alpha; IFN-alphaA; INFA2; interferon alpha 2; LeIF D

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Citations for Mouse IFN-alpha Fluorescein MAb (Clone RMMA-1)

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

5 Citations: Showing 1 - 5
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  1. SARS-CoV-2 spike protein promotes inflammatory cytokine activation and aggravates rheumatoid arthritis
    Authors: A Ram Lee, Jin Seok Woo, Seon-Yeong Lee, Yeon Su Lee, Jooyeon Jung, Chae Rim Lee et al.
    Cell Communication and Signaling
  2. Innate Immune Training of Granulopoiesis Promotes Anti-tumor Activity
    Authors: Lydia Kalafati, Ioannis Kourtzelis, Jonas Schulte-Schrepping, Xiaofei Li, Aikaterini Hatzioannou, Tatyana Grinenko et al.
    Cell
  3. Alcohol enhances type 1 interferon-? production and mortality in young mice infected with Mycobacterium tuberculosis
    Authors: D Tripathi, E Welch, SS Cheekatla, RK Radhakrish, S Venkatasub, P Paidipally, A Van, B Samten, KP Devalraju, VSK Neela, VL Valluri, C Mason, S Nelson, R Vankayalap
    PLoS Pathog., 2018-08-02;14(8):e1007174.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  4. Systemic RNA delivery to dendritic cells exploits antiviral defence for cancer immunotherapy
    Authors: Lena M Kranz
    Nature, 2016-06-01;534(7607):396-401.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Flow Cytometry
  5. Type I IFNs Regulate Inflammation, Vasculopathy, and Fibrosis in Chronic Cutaneous Graft-versus-Host Disease
    J Immunol, 2016-05-25;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr

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