Mouse Fc epsilon RI beta/MS4A2 (NP_038544) VersaClone cDNA

Catalog # Availability Size / Price Qty
RDC0230
R&D Systems VersaClone cDNA Plasmids
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Mouse Fc epsilon RI beta/MS4A2 (NP_038544) VersaClone cDNA Summary

Specifications

Source
N/A
Shipping Conditions
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Storage
Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.
Species
Mouse

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Background: Fc epsilon RI beta/MS4A2

The allergic response involves the binding of allergen to receptor-bound IgE followed by cell activation and the release of mediators responsible for the manifestations of allergy. The IgE-receptor, a tetramer composed of an alpha, beta, and 2 disulfide-linked gamma chains, is found on the surface of mast cells and basophils. Fc epsilon RI beta/MS4A2 is the beta subunit of the high affinity IgE receptor which is a member of the membrane-spanning 4A gene family. Members of this nascent protein family are characterized by common structural features and similar intron/exon splice boundaries and display unique expression patterns among hematopoietic cells and nonlymphoid tissues. Fc epsilon RI beta seems to be a risk factor for atopic dermatitis and asthma.

Long Name
Fc epsilon Receptor I beta
Entrez Gene IDs
2206 (Human); 14126 (Mouse); 25316 (Rat)
Alternate Names
APY; ATOPY; Fc epsilon receptor I beta-chain; Fc epsilon RI beta; Fc epsilonRIb; FCER1B; FCER1BIGEL; FCERI; High affinity immunoglobulin epsilon receptor beta-subunit (FcERI) (IgE Fcreceptor, beta-subunit) (Fc epsilon receptor I beta-chain); high affinity immunoglobulin epsilon receptor subunit beta; IgE Fc receptor subunit beta; IgE responsiveness (atopic); IGEL; IGER; IGHER; immunoglobulin E receptor, high affinity, beta polypeptide; Membrane-spanning 4-domains subfamily A member 2; membrane-spanning 4-domains, subfamily A, member 2 (Fc fragment of IgE, highaffinity I, receptor for; beta polypeptide); MS4A1; MS4A2

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