Mouse CXCL2/MIP-2 Quantikine ELISA Kit Summary
Product Summary
Precision
Cell Culture Supernates, Serum
Intra-Assay Precision | Inter-Assay Precision | |||||
---|---|---|---|---|---|---|
Sample | 1 | 2 | 3 | 1 | 2 | 3 |
n | 20 | 20 | 20 | 20 | 20 | 20 |
Mean (pg/mL) | 17.7 | 53.9 | 363 | 16.9 | 52.1 | 346 |
Standard Deviation | 0.5 | 1.3 | 7.3 | 1 | 2.3 | 15.4 |
CV% | 2.8 | 2.4 | 2 | 5.9 | 4.4 | 4.5 |
Recovery
The recovery of mouse MIP-2 spiked to three levels throughout the range of the assay in various matrices was evaluated.
Sample Type | Average % Recovery | Range % |
---|---|---|
Cell Culture Supernates (n=10) | 96 | 84-110 |
Serum (n=14) | 100 | 94-116 |
Linearity
Scientific Data
Product Datasheets
Preparation and Storage
Background: CXCL2/GRO beta/MIP-2/CINC-3
CXCL2/GRO beta, also called MIP-2 in mouse and CINC-3 in rat, is a member of the CXC chemokine family. Human CXCL2/GRO beta is 107 amino acids (aa) in length with a predicted molecular weight of 11 kDa. The mouse and rat orthologs share 70% and 71% aa sequence identity with the human protein, respectively. N-terminal aa 1-4 of CXCL2/GRO beta can be post-translationally cleaved which confers enhanced hematopoietic bioactivity. CXCL2/GRO beta is produced by a variety of cell types including monocytes and macrophages at sites of inflammation and is chemotactic for granulocytes, including neutrophils.
Assay Procedure
Refer to the product- Prepare all reagents, standard dilutions, and samples as directed in the product insert.
- Remove excess microplate strips from the plate frame, return them to the foil pouch containing the desiccant pack, and reseal.
- Add 50 µL of Assay Diluent to each well.
- Add 50 µL of Standard, Control, or sample to each well. Cover with a plate sealer, and incubate at room temperature for 2 hours.
- Aspirate each well and wash, repeating the process 4 times for a total of 5 washes.
- Add 100 µL of Conjugate to each well. Cover with a new plate sealer, and incubate at room temperature for 2 hours.
- Aspirate and wash 5 times.
- Add 100 µL Substrate Solution to each well. Incubate at room temperature for 30 minutes. PROTECT FROM LIGHT.
- Add 100 µL of Stop Solution to each well. Read at 450 nm within 30 minutes. Set wavelength correction to 540 nm or 570 nm.
Citations for Mouse CXCL2/MIP-2 Quantikine ELISA Kit
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Spinal cord injury disrupts plasma extracellular vesicles cargoes leading to neuroinflammation in the brain and neurological dysfunction in aged male mice
Authors: Lei, Z;Krishnamachary, B;Khan, NZ;Ji, Y;Li, Y;Li, H;Brunner, K;Faden, AI;Jones, JW;Wu, J;
Brain, behavior, and immunity
Species: Mouse
Sample Types: Cell Culture Supernates
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Platelet-activating factor and protease-activated receptor 2 cooperate to promote neutrophil recruitment and lung inflammation through nuclear factor-kappa B transactivation
Authors: Silva, IS;Almeida, AD;Lima Filho, ACM;Fernandes-Braga, W;Barra, A;Oliveira, HMC;Cassali, GD;Capettini, LSA;Menezes, GB;Alvarez-Leite, JI;Leite, MF;Klein, A;
Scientific reports
Species: Mouse
Sample Types: BALF
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Ethanol Extracts from the Aerial Parts of Inula japonica and Potentilla chinensis Alleviate Airway Inflammation in Mice That Inhaled Particulate Matter 10 and Diesel Particulate Matter
Authors: Jung, SH;Chung, KS;Na, CS;Ahn, HS;Shin, YK;Lee, KT;
Nutrients
Species: Mouse
Sample Types: BALF
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Neutrophil metalloproteinase driven spleen damage hampers infection control of trypanosomiasis
Authors: Pham, HTT;Magez, S;Choi, B;Baatar, B;Jung, J;Radwanska, M;
Nature communications
Species: Mouse
Sample Types: Tissue Homogenates
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Naegleria fowleri Extracellular Vesicles Induce Proinflammatory Immune Responses in BV-2 Microglial Cells
Authors: Lê, HG;Kang, JM;Võ, TC;Yoo, WG;Na, BK;
International journal of molecular sciences
Species: Mouse
Sample Types: Cell Culture Supernates
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LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis
Authors: Sha, L;Li, J;Shen, H;Wang, Q;Meng, P;Zhang, X;Deng, Y;Zhu, W;Xu, Q;
Cell reports
Species: Mouse
Sample Types: Cell Culture Supernates
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The Scap-SREBP1-S1P/S2P lipogenesis signal orchestrates the homeostasis and spatiotemporal activation of NF-?B
Authors: Fei, X;Huang, J;Li, F;Wang, Y;Shao, Z;Dong, L;Wu, Y;Li, B;Zhang, X;Lv, B;Zhao, Y;Weng, Q;Chen, K;Zhang, M;Yang, S;Zhang, C;Zhang, M;Li, W;Ying, S;Sun, Q;Chen, Z;Shen, H;
Cell reports
Species: Mouse
Sample Types: BALF, Cell Culture Supernates
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Age-related changes in plasma extracellular vesicles influence neuroinflammation in the brain and neurological outcome after traumatic spinal cord injury
Authors: Lei, Z;Krishnamachary, B;Ritzel, RM;Khan, NZ;Li, Y;Li, H;Brunner, K;Faden, AI;Wu, J;
Research square
Species: Mouse
Sample Types: Cell Culture Supernates
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Mechanism and intervention of murine transfusion-related acute lung injury caused by anti-CD36 antibodies
Authors: DW Chen, T Kang, XZ Xu, WJ Xia, X Ye, YB Wu, YR Xu, J Liu, H Ren, J Deng, YK Chen, HQ Ding, M Aslam, WM Zelek, BP Morgan, R Kapur, S Santoso, YS Fu
JCI Insight, 2023-03-22;0(0):.
Species: Mouse
Sample Types: BALF
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METTL3-mediated m6A mRNA methylation regulates neutrophil activation through targeting TLR4 signaling
Authors: S Luo, C Liao, L Zhang, C Ling, X Zhang, P Xie, G Su, Z Chen, L Zhang, T Lai, J Tang
Cell Reports, 2023-03-14;42(3):112259.
Species: Mouse
Sample Types: Cell Culture Supernates
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Glutamine prevents acute kidney injury by modulating oxidative stress and apoptosis in tubular epithelial cells
Authors: K Thomas, L Zondler, N Ludwig, M Kardell, C Lüneburg, K Henke, S Mersmann, A Margraf, T Spieker, T Tekath, A Velic, R Holtmeier, J Hermann, V Jankowski, M Meersch, D Vestweber, M Westphal, J Roth, MA Schäfers, JA Kellum, CA Lowell, J Rossaint, A Zarbock
JCI Insight, 2022-11-08;7(21):.
Species: Mouse
Sample Types: Urine
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Tubule-mitophagic secretion of SerpinG1 reprograms macrophages to instruct anti-septic acute kidney injury efficacy of high-dose ascorbate mediated by NRF2 transactivation
Authors: Y Ni, GH Wu, JJ Cai, R Zhang, Y Zheng, JQ Liu, XH Yang, X Yang, Y Shen, JM Lai, XM Ye, SJ Mo
International journal of biological sciences, 2022-08-08;18(13):5168-5184.
Species: Mouse
Sample Types: Cell Culture Supernates
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Nanoparticles reduce monocytes within the lungs to improve outcomes after influenza virus infection in aged mice
Authors: WJ Kelley, KM Wragg, J Chen, T Murthy, Q Xu, MT Boyne Ii, JR Podojil, A Elhofy, DR Goldstein
JCI Insight, 2022-08-08;0(0):.
Species: Mouse
Sample Types: BALF
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Generation of antagonistic monoclonal antibodies against the neoepitope of active mouse interleukin (IL)-18 cleaved by inflammatory caspases
Authors: Y Uchida, Y Nariai, E Obayashi, Y Tajima, T Koga, A Kawakami, T Urano, H Kamino
Oncogene, 2022-06-13;727(0):109322.
Species: Mouse
Sample Types: Cell Culture Supernates
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SGK1 negatively regulates inflammatory immune responses and protects against alveolar bone loss through modulation of TRAF3 activity
Authors: X Han, J Ren, H Lohner, L Yakoumatos, R Liang, H Wang
The Journal of Biological Chemistry, 2022-05-17;0(0):102036.
Species: Mouse
Sample Types: Cell Culture Supernates
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Cytokines and Neurodegeneration in Epileptogenesis
Authors: P Wolinski, D Ksiazek-Wi, A Glabinski
Brain sciences, 2022-03-12;12(3):.
Species: Mouse
Sample Types: Tissue Homogenates
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Intestinal microbe-dependent ?3 lipid metabolite alphaKetoA prevents inflammatory diseases in mice and cynomolgus macaques
Authors: T Nagatake, S Kishino, E Urano, H Murakami, N Kitamura, K Konishi, H Ohno, P Tiwari, S Morimoto, E Node, J Adachi, Y Abe, J Isoyama, K Sawane, T Honda, A Inoue, A Uwamizu, T Matsuzaka, Y Miyamoto, SI Hirata, A Saika, Y Shibata, K Hosomi, A Matsunaga, H Shimano, M Arita, J Aoki, M Oka, A Matsutani, T Tomonaga, K Kabashima, M Miyachi, Y Yasutomi, J Ogawa, J Kunisawa
Mucosal Immunology, 2022-01-10;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Role of S100A8/A9 for Cytokine Secretion, Revealed in Neutrophils Derived from ER-Hoxb8 Progenitors
Authors: Y Zhou, J Hann, V Schenten, S Plançon, JL Bueb, F Tolle, S Bréchard
International Journal of Molecular Sciences, 2021-08-17;22(16):.
Species: Mouse
Sample Types: Cell Culture Supernates
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Pseudomonas aeruginosa-induced nociceptor activation increases susceptibility to infection
Authors: T Lin, D Quellier, J Lamb, T Voisin, P Baral, F Bock, A Schönberg, R Mirchev, G Pier, I Chiu, M Gadjeva
PloS Pathogens, 2021-05-06;17(5):e1009557.
Species: Mouse
Sample Types: Tissue Homogenates
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Phorbol 12-Myristate 13-Acetate Induced Toxicity Study and the Role of Tangeretin in Abrogating HIF-1&alpha-NF-&kappaB Crosstalk In Vitro and In Vivo
Authors: SN Chang, DK Dey, ST Oh, WH Kong, KH Cho, EM Al-Olayan, BS Hwang, SC Kang, JG Park
International Journal of Molecular Sciences, 2020-12-04;21(23):.
Species: Mouse
Sample Types: Tissue Culture Supernates
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The Gustatory Sensory G-Protein GNAT3 Suppresses Pancreatic Cancer Progression in Mice
Authors: MT Hoffman, SB Kemp, DJ Salas-Esca, Y Zhang, NG Steele, S The, D Long, S Benitz, W Yan, RF Margolskee, F Bednar, M Pasca di M, HJ Wen, HC Crawford
Cell Mol Gastroenterol Hepatol, 2020-08-31;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Nintedanib Reduces Neutrophil Chemotaxis via Activating GRK2 in Bleomycin-Induced Pulmonary Fibrosis
Authors: WC Chen, NJ Chen, HP Chen, WK Yu, VY Su, H Chen, HH Wu, KY Yang
Int J Mol Sci, 2020-07-02;21(13):.
Species: Mouse
Sample Types: Tissue Homogenates
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ASK1 promotes uterine inflammation leading to pathological preterm birth
Authors: M Yoshikawa, T Iriyama, K Suzuki, S Sayama, T Tsuruga, K Kumasawa, T Nagamatsu, K Homma, I Naguro, Y Osuga, H Ichijo, T Fujii
Sci Rep, 2020-02-05;10(1):1887.
Species: Mouse
Sample Types: Peritoneal Fluid
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Cysteine-Capped Hydrogels Incorporating Copper as Effective Antimicrobial Materials against Methicillin-Resistant Staphylococcus aureus
Authors: JJ Yang, YC Huang, TH Chuang, DR Herr, MF Hsieh, CJ Huang, CM Huang
Microorganisms, 2020-01-21;8(2):.
Species: Mouse
Sample Types: Tissue Homogenates
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Lack of whey acidic protein four disulphide core (WFDC) 2 protease inhibitor causes neonatal death from respiratory failure in mice
Authors: K Nakajima, M Ono, U Radovi?, S Dizdarevi?, SI Tomizawa, K Kuroha, G Naganatsu, I Hoshi, R Matsunaga, T Shirakawa, T Kurosawa, Y Miyazaki, M Seki, Y Suzuki, H Koseki, M Nakamura, T Suda, K Ohbo
Dis Model Mech, 2019-11-12;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Adoptive transfer of type 1 regulatory T cells suppressed the development of airway hyperresponsiveness in ovalbumin-induced airway inflammation model mice
Authors: M Matsuda, K Doi, T Tsutsumi, M Inaba, J Hamaguchi, T Terada, R Kawata, K Kitatani, T Nabe
J. Pharmacol. Sci., 2019-11-02;141(4):139-145.
Species: Mouse
Sample Types: BALF
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Isoflavone Aglycones Attenuate Cigarette Smoke-Induced Emphysema via Suppression of Neutrophilic Inflammation in a COPD Murine Model
Authors: K Kojima, K Asai, H Kubo, A Sugitani, Y Kyomoto, A Okamoto, K Yamada, N Ijiri, T Watanabe, K Hirata, T Kawaguchi
Nutrients, 2019-08-29;11(9):.
Species: Mouse
Sample Types: BALF
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Inactivation of MTOR promotes autophagy-mediated epithelial injury in particulate matter-induced airway inflammation
Authors: YF Wu, ZY Li, LL Dong, WJ Li, YP Wu, J Wang, HP Chen, HW Liu, M Li, CL Jin, HQ Huang, SM Ying, W Li, HH Shen, ZH Chen
Autophagy, 2019-06-16;0(0):1-16.
Species: Mouse
Sample Types: BALF
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Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells
Authors: N Simon, A Antignani, SM Hewitt, M Gadina, C Alewine, D FitzGerald
JCI Insight, 2019-03-07;0(0):.
Species: Mouse
Sample Types: Serum
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Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust
Authors: KJ Warren, JD Dickinson, AJ Nelson, TA Wyatt, DJ Romberger, JA Poole
Respir. Res., 2019-03-07;20(1):51.
Species: Mouse
Sample Types: BALF
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Induced Pluripotent Stem Cells Regulate TREM-1 Expression and the p38 MAPK Pathway in Endotoxin-Induced Acute Lung Injury
Authors: VY Su, KY Yang, SH Chiou, NJ Chen, MH Mo, CS Lin, CT Wang
Stem Cells, 2019-02-16;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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1-Palmitoyl-2-linoleoyl-3-acetyl-rac-glycerol (PLAG) attenuates gemcitabine-induced neutrophil extravasation
Authors: J Jeong, YJ Kim, DY Lee, BG Moon, KY Sohn, SY Yoon, JW Kim
Cell Biosci, 2019-01-03;9(0):4.
Species: Mouse
Sample Types: Cell Culture Supernates
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Endothelial cell-specific anticoagulation reduces inflammation in a mouse model of acute lung injury
Authors: J Lou, Y Hu, MD Wu, LQ Che, YF Wu, Y Zhao, BP Tian, ZQ Bao, C Zhu, YP Wu, LL He, CX Bai, J Zhou, SM Ying, W Li, ZH Chen, DX Chen, A Dorling, HH Shen
Acta Pharmacol. Sin., 2018-11-16;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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Snail promotes ovarian cancer progression by recruiting myeloid-derived suppressor cells via CXCR2 ligand upregulation
Authors: M Taki, K Abiko, T Baba, J Hamanishi, K Yamaguchi, R Murakami, K Yamanoi, N Horikawa, Y Hosoe, E Nakamura, A Sugiyama, M Mandai, I Konishi, N Matsumura
Nat Commun, 2018-04-27;9(1):1685.
Species: Mouse
Sample Types: Serum
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TIM?4 blockade of KCs combined with exogenous TGF?β injection helps to reverse acute rejection and prolong the survival rate of mice receiving liver allografts
Authors: H Wu, X Xu, J Li, J Gong, M Li
Int. J. Mol. Med., 2018-03-30;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages
Authors: Z Li, Y Wu, H Chen, C Zhu, L Dong, Y Wang, H Liu, X Xu, J Zhou, Y Wu, W Li, S Ying, H Shen, Z Chen
J. Immunol., 2018-03-21;0(0):.
Species: Mouse
Sample Types: BALF
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Age-related decline of the acute local inflammation response: a mitigating role for the adenosine A2A receptor
Authors: C Laflamme, GB Mailhot, M Pouliot
Aging (Albany NY), 2017-10-18;9(10):2083-2097.
Species: Mouse
Sample Types: Air Pouch Exudate
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Two novel roles of buffalo milk lactoperoxidase, antibiofilm agent and immunomodulator against multidrug resistant Salmonella enterica serovar Typhi and Listeria monocytogenes
Authors: L Mahdi, H Musafer, L Zwain, I Salman, I Al-Joofy, K Rasool, A Mussa, S Al-Kakei, R Al-Oqaili, S Al-Alak, A Chaloob, A Abdulkaree, B Hussein, N Mahdi, N Taher
Microb. Pathog., 2017-06-03;0(0):.
Species: Mouse
Sample Types: Serum
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Antiinflammatory actions of inorganic nitrate stabilize the atherosclerotic plaque
Authors: RS Khambata, SM Ghosh, KS Rathod, T Thevathasa, F Filomena, Q Xiao, A Ahluwalia
Proc. Natl. Acad. Sci. U.S.A, 2017-01-05;0(0):.
Species: Mouse
Sample Types: Plasma
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Systemic IL-6 Effector Response in Mediating Systemic Bone Loss Following Inhalation of Organic Dust
Authors: Jill A Poole
J. Interferon Cytokine Res., 2016-11-22;0(0):.
Species: Mouse
Sample Types: BALF
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Targeting thrombomodulin to circulating red blood cells augments its protective effects in models of endotoxemia and ischemia-reperfusion injury
Authors: Vladimir R Muzykantov
FASEB J., 2016-11-11;0(0):.
Species: Mouse
Sample Types: Plasma
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Plasminogen activator inhibitor-1 does not contribute to the pulmonary pathology induced by acute exposure to ozone
Physiol Rep, 2016-09-01;4(18):.
Species: Mouse
Sample Types: BALF
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CF Lung Infection and Inflammation: IL-17 Pathophysiology and Therapeutic Intervention
Authors: Daniel Hsu
Infect Immun, 2016-08-19;0(0):.
Species: Mouse
Sample Types: BALF
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Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
PLoS ONE, 2016-08-01;11(8):e0158735.
Species: Mouse
Sample Types: BALF
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Toll-like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice
Authors: S Nakamura, N Iwanaga, M Seki, K Fukudome, K Oshima, T Miyazaki, K Izumikawa, K Yanagihara, Y Miyazaki, H Mukae, S Kohno
Infect Immun, 2016-06-23;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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CD11c.DTR mice develop a fatal fulminant myocarditis after local or systemic treatment with diphtheria toxin
Eur J Immunol, 2016-06-08;0(0):.
Species: Mouse
Sample Types: Tissue Homogenates
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DUOX-Mediated Signaling Is Not Required for LPS-Induced Neutrophilic Response in the Airways.
Authors: Chang S, Linderholm A, Harper R
PLoS ONE, 2015-07-06;10(7):e0131810.
Species: Mouse
Sample Types: BALF
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Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis.
Authors: Lu H, Poirier C, Cook T, Traktuev D, Merfeld-Clauss S, Lease B, Petrache I, March K, Bogatcheva N
J Transl Med, 2015-02-21;13(0):67.
Species: Mouse
Sample Types: BALF
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Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice.
Authors: Dugan J, Griffiths E, Snow P, Rosenzweig H, Lee E, Brown B, Carr D, Rose C, Rosenbaum J, Davey M
J Immunol, 2014-11-26;194(1):349-57.
Species: Mouse
Sample Types: Serum
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Nuclear factor of activated T cells regulates neutrophil recruitment, systemic inflammation, and T-cell dysfunction in abdominal sepsis.
Authors: Zhang S, Luo L, Wang Y, Gomez M, Thorlacius H
Infect Immun, 2014-05-27;82(8):3275-88.
Species: Mouse
Sample Types: Tissue Homogenates
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Recombinant human hyaluronidase PH20 does not stimulate an acute inflammatory response and inhibits lipopolysaccharide-induced neutrophil recruitment in the air pouch model of inflammation.
Authors: Huang Z, Zhao C, Chen Y, Cowell J, Wei G, Kultti A, Huang L, Thompson C, Rosengren S, Frost G, Shepard H
J Immunol, 2014-04-28;192(11):5285-95.
Species: Mouse
Sample Types: Cell Culture Supernates
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Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2.
Authors: Tancevski I, Nairz M, Duwensee K, Auer K, Schroll A, Heim C, Feistritzer C, Hoefer J, Gerner R, Moschen A, Heller I, Pallweber P, Li X, Theurl M, Demetz E, Wolf A, Wolf D, Eller P, Ritsch A, Weiss G
EMBO Mol Med, 2014-04-06;6(6):810-20.
Species: Mouse
Sample Types: Cell Culture Supernates
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Peripheral blood monocyte-derived chemokine blockade prevents murine transfusion-related acute lung injury (TRALI).
Authors: McKenzie C, Kim M, Singh T, Milev Y, Freedman J, Semple J
Blood, 2014-03-17;123(22):3496-503.
Species: Mouse
Sample Types: Serum
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Blockade of Fas signaling in breast cancer cells suppresses tumor growth and metastasis via disruption of Fas signaling-initiated cancer-related inflammation.
Authors: Liu Q, Tan Q, Zheng Y, Chen K, Qian C, Li N, Wang Q, Cao X
J Biol Chem, 2014-03-13;289(16):11522-35.
Species: Mouse
Sample Types: Whole Cells
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Pseudomonas aeruginosa MucD protease mediates keratitis by inhibiting neutrophil recruitment and promoting bacterial survival.
Authors: Mochizuki Y, Suzuki T, Oka N, Zhang Y, Hayashi Y, Hayashi N, Gotoh N, Ohashi Y
Invest Ophthalmol Vis Sci, 2014-01-09;55(1):240-6.
Species: Mouse
Sample Types: Tissue Homogenates
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Vascular immunotargeting to endothelial determinant ICAM-1 enables optimal partnering of recombinant scFv-thrombomodulin fusion with endogenous cofactor.
Authors: Greineder, Colin F, Chacko, Ann-Mari, Zaytsev, Sergei, Zern, Blaine J, Carnemolla, Ronald, Hood, Elizabet, Han, Jingyan, Ding, Bi-Sen, Esmon, Charles, Muzykantov, Vladimir
PLoS ONE, 2013-11-14;8(11):e80110.
Species: Mouse
Sample Types: Lavage Fluid
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CXCR2-mediated tumor-associated neutrophil recruitment is regulated by IFN-beta.
Authors: Jablonska J, Wu C, Andzinski L, Leschner S, Weiss S
Int J Cancer, 2013-10-31;134(6):1346-58.
Species: Mouse
Sample Types: Tissue Homogenates
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A novel C5a-neutralizing mirror-image (l-)aptamer prevents organ failure and improves survival in experimental sepsis.
Authors: Hoehlig, Kai, Maasch, Christia, Shushakova, Nelli, Buchner, Klaus, Huber-Lang, Markus, Purschke, Werner G, Vater, Axel, Klussmann, Sven
Mol Ther, 2013-07-26;21(12):2236-46.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
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Inhibition of geranylgeranyltransferase attenuates neutrophil accumulation and tissue injury in severe acute pancreatitis.
Authors: Merza M, Wetterholm E, Zhang S, Regner S, Thorlacius H
J Leukoc Biol, 2013-06-06;94(3):493-502.
Species: Mouse
Sample Types: Tissue Homogenates
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Characterization of a distinct host response profile to Pneumocystis murina asci during clearance of pneumocystis pneumonia.
Authors: Linke M, Ashbaugh A, Collins M, Lynch K, Cushion M
Infect Immun, 2013-01-14;81(3):984-95.
Species: Mouse
Sample Types: Cell Culture Supernates
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Endothelial cell peroxisome proliferator-activated receptor gamma reduces endotoxemic pulmonary inflammation and injury.
Authors: Reddy A, Lakshmi S, Kleinhenz J, Sutliff R, Hart C, Reddy R
J Immunol, 2012-10-26;189(11):5411-20.
Species: Mouse
Sample Types: BALF
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Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.
Authors: Ylostalo J, Bartosh T, Coble K, Prockop D
Stem Cells, 2012-10-01;30(10):2283-96.
Species: Mouse
Sample Types: Cell Culture Supernates
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CRTH2 Is A Critical Regulator of Neutrophil Migration and Resistance to Polymicrobial Sepsis.
Authors: Ishii M, Asano K, Namkoong H, Tasaka S, Mizoguchi K, Asami T, Kamata H, Kimizuka Y, Fujiwara H, Funatsu Y, Kagawa S, Miyata J, Ishii K, Nakamura M, Hirai H, Nagata K, Kunkel SL, Hasegawa N, Betsuyaku T
J. Immunol., 2012-04-27;188(11):5655-64.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
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Inhibiting Mer receptor tyrosine kinase suppresses STAT1, SOCS1/3, and NF-kappaB activation and enhances inflammatory responses in lipopolysaccharide-induced acute lung injury.
J. Cell. Sci., 2012-03-16;91(6):921-32.
Species: Mouse
Sample Types: BALF
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Modelling of mouse experimental colitis by global property screens: a holistic approach to assess drug effects in inflammatory bowel disease.
Authors: Gottfries J, Melgar S, Michaelsson E
PLoS ONE, 2012-01-18;7(1):e30005.
Species: Mouse
Sample Types: Tissue Homogenates
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Neutrophil-derived matrix metalloproteinase-9 is a potent activator of trypsinogen in acinar cells in acute pancreatitis.
Authors: Awla D, Abdulla A, Syk I, Jeppsson B, Regner S, Thorlacius H
J. Leukoc. Biol., 2011-11-18;91(5):711-9.
Species: Mouse
Sample Types: Serum
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Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus.
Authors: Walsh KB, Teijaro JR, Wilker PR
Proc. Natl. Acad. Sci. U.S.A., 2011-06-29;108(29):12018-23.
Species: Mouse
Sample Types: BALF
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Involvement of adenosine A2A receptors in engulfment-dependent apoptotic cell suppression of inflammation.
Authors: Koroskenyi K, Duro E, Pallai A, Sarang Z, Kloor D, Ucker DS, Beceiro S, Castrillo A, Chawla A, Ledent CA, Fésüs L, Szondy Z
J. Immunol., 2011-05-18;186(12):7144-55.
Species: Mouse
Sample Types: Cell Culture Supernates
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TNF-alpha promotes LPA1- and LPA3-mediated recruitment of leukocytes in vivo through CXCR2 ligand chemokines.
Authors: Zhao C, Sardella A, Chun J, Poubelle PE, Fernandes MJ, Bourgoin SG
J. Lipid Res., 2011-04-26;52(7):1307-18.
Species: Mouse
Sample Types: Air Pouch Exudate
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CXCL1 and its receptor, CXCR2, mediate murine sickle cell vaso-occlusion during hemolytic transfusion reactions.
Authors: Jang JE, Hod EA, Spitalnik SL
J. Clin. Invest., 2011-03-07;121(4):1397-401.
Species: Mouse
Sample Types: Plasma
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Overexpression of sICAM-1 in the Alveolar Epithelial Space Results in an Exaggerated Inflammatory Response and Early Death in Gram Negative Pneumonia.
Authors: Mendez MP, Monroy YK, Du M
Respir. Res., 2011-01-19;12(1):12.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
J. Immunol., 2010-11-22;186(1):556-62.
Species: Mouse
Sample Types: BALF
-
Priming with endotoxin increases acute lung injury in mice by enhancing the severity of lung endothelial injury.
Authors: Lee JS, Su X, Rackley C, Matthay MA, Gupta N
Anat Rec (Hoboken), 2010-11-16;294(1):165-72.
Species: Mouse
Sample Types: BALF
-
S100A8/A9 is not involved in host defense against murine urinary tract infection.
Authors: Dessing MC, Butter LM, Teske GJ
PLoS ONE, 2010-10-14;5(10):e13394.
Species: Mouse
Sample Types: Tissue Homogenates
-
Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
Authors: Ito H, Hoshi M, Ohtaki H, Taguchi A, Ando K, Ishikawa T, Osawa Y, Hara A, Moriwaki H, Saito K, Seishima M
J. Immunol., 2010-09-15;185(8):4554-60.
Species: Mouse
Sample Types: Serum
-
Uropathogenic Escherichia coli modulates immune responses and its curli fimbriae interact with the antimicrobial peptide LL-37.
Authors: Kai-Larsen Y, Luthje P, Chromek M, Peters V, Wang X, Holm A, Kadas L, Hedlund KO, Johansson J, Chapman MR, Jacobson SH, Romling U, Agerberth B, Brauner A
PLoS Pathog., 2010-07-22;6(0):e1001010.
Species: Mouse
Sample Types: Urine
-
Recipient T lymphocytes modulate the severity of antibody-mediated transfusion-related acute lung injury.
Authors: Fung YL, Kim M, Tabuchi A
Blood, 2010-07-08;116(16):3073-9.
Species: Mouse
Sample Types: Serum
-
P2X7 receptor activation induces CXCL2 production in microglia through NFAT and PKC/MAPK pathways.
Authors: Shiratori M, Tozaki-Saitoh H, Yoshitake M
J. Neurochem., 2010-05-13;114(3):810-9.
Species: Mouse
Sample Types: Cell Culture Supernates
-
NOD1 contributes to mouse host defense against Helicobacter pylori via induction of type I IFN and activation of the ISGF3 signaling pathway.
Authors: Watanabe T, Asano N, Fichtner-Feigl S, Gorelick PL, Tsuji Y, Matsumoto Y, Chiba T, Fuss IJ, Kitani A, Strober W
J. Clin. Invest., 2010-04-12;120(5):1645-62.
Species: Mouse
Sample Types: Cell Culture Supernates
-
TLR4 is a negative regulator in noninfectious lung inflammation.
Authors: Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA
J. Immunol., 2010-03-31;184(9):5308-14.
Species: Mouse
Sample Types: BALF
-
Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
Cytokine, 2009-12-29;49(3):256-63.
Species: Mouse
Sample Types: BALF
-
Absence or inhibition of matrix metalloproteinase-8 decreases ventilator-induced lung injury.
Authors: Albaiceta GM, Gutierrez-Fernandez A, Garcia-Prieto E, Puente XS, Parra D, Astudillo A, Campestre C, Cabrera S, Gonzalez-Lopez A, Fueyo A, Taboada F, Lopez-Otin C
Am. J. Respir. Cell Mol. Biol., 2009-12-07;43(5):555-63.
Species: Mouse
Sample Types: Tissue Homogenates
-
Both FcgammaRIV and FcgammaRIII are essential receptors mediating type II and type III autoimmune responses via FcRgamma-LAT-dependent generation of C5a.
Authors: Syed SN, Konrad S, Wiege K, Nieswandt B, Nimmerjahn F, Schmidt RE, Gessner JE
Eur. J. Immunol., 2009-12-01;39(12):3343-56.
Species: Mouse
Sample Types: BALF
-
Epithelial overexpression of SOCS-3 in transgenic mice exacerbates wound inflammation in the presence of elevated TGF-beta1.
Authors: Linke A, Goren I, Bosl MR, Pfeilschifter J, Frank S
J. Invest. Dermatol., 2009-11-19;130(3):866-75.
Species: Mouse
Sample Types: Tissue Homogenates
-
Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene.
Authors: Sio SW, Moochhala S, Lu J
Am. J. Respir. Crit. Care Med., 2009-10-01;181(1):36-46.
Species: Mouse
Sample Types: Tissue Homogenates
-
Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
Am. J. Respir. Crit. Care Med., 2009-09-17;180(12):1208-17.
Species: Mouse
Sample Types: BALF
-
Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
Authors: Pini M, Fantuzzi G
J. Leukoc. Biol., 2009-09-10;87(1):51-8.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
Authors: Hayashida K, Parks WC, Park PW
Blood, 2009-07-28;114(14):3033-43.
Species: Mouse
Sample Types: Serum
-
TLR9 activation coupled to IL-10 deficiency induces adverse pregnancy outcomes.
Authors: Thaxton JE, Romero R, Sharma S
J. Immunol., 2009-06-26;183(2):1144-54.
Species: Mouse
Sample Types: Serum
-
IL-17 receptor signaling is required to control polymicrobial sepsis.
Authors: Freitas A, Alves-Filho JC, Victoni T, Secher T, Lemos HP, Sonego F, Cunha FQ, Ryffel B
J. Immunol., 2009-06-15;182(12):7846-54.
Species: Mouse
Sample Types: Tissue Secretion
-
T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
Authors: Guarda G, Dostert C, Staehli F, Cabalzar K, Castillo R, Tardivel A, Schneider P, Tschopp J
Nature, 2009-06-03;460(7252):269-73.
Species: Mouse
Sample Types: Cell Culture Supernates
-
C/EBPalpha is required for pulmonary cytoprotection during hyperoxia.
Authors: Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M
Am. J. Physiol. Lung Cell Mol. Physiol., 2009-05-22;297(2):L286-98.
Species: Mouse
Sample Types: Tissue Homogenates
-
The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion.
Authors: Kato N, Yuzawa Y, Kosugi T
J. Am. Soc. Nephrol., 2009-05-14;20(7):1565-76.
Species: Mouse
Sample Types: Tissue Homogenates
-
Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation.
Authors: Ding BS, Hong N, Christofidou-Solomidou M, Gottstein C, Albelda SM, Cines DB, Fisher AB, Muzykantov VR
Am. J. Respir. Crit. Care Med., 2009-04-02;180(3):247-56.
Species: Mouse
Sample Types: BALF
-
Acute lung injury is reduced in fat-1 mice endogenously synthesizing n-3 fatty acids.
Authors: Mayer K, Kiessling A, Ott J, Schaefer MB, Hecker M, Henneke I, Schulz R, Gunther A, Wang J, Wu L, Roth J, Seeger W, Kang JX
Am. J. Respir. Crit. Care Med., 2009-01-08;179(6):474-83.
Species: Mouse
Sample Types: BALF
-
A small molecule CRTH2 antagonist inhibits FITC-induced allergic cutaneous inflammation.
Authors: Boehme SA, Franz-Bacon K, Chen EP, Sasik R, Sprague LJ, Ly TW, Hardiman G, Bacon KB
Int. Immunol., 2008-12-09;21(1):81-93.
Species: Mouse
Sample Types: Tissue Homogenates
-
Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
Kidney Int., 2008-09-17;75(1):52-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.
Authors: Zhang H, Moochhala SM, Bhatia M
J. Immunol., 2008-09-15;181(6):4320-31.
Species: Mouse
Sample Types: Tissue Homogenates
-
TLR-2 and IL-17A in chitin-induced macrophage activation and acute inflammation.
Authors: Da Silva CA, Hartl D, Liu W, Lee CG, Elias JA
J. Immunol., 2008-09-15;181(6):4279-86.
Species: Mouse
Sample Types: BALF
-
Particulate matter in cigarette smoke alters iron homeostasis to produce a biological effect.
Authors: Ghio AJ, Hilborn ED, Stonehuerner JG, Dailey LA, Carter JD, Richards JH, Crissman KM, Foronjy RF, Uyeminami DL, Pinkerton KE
Am. J. Respir. Crit. Care Med., 2008-08-21;178(11):1130-8.
Species: Rat
Sample Types: BALF
-
The nuclear factor kappa-B pathway in airway epithelium regulates neutrophil recruitment and host defence following Pseudomonas aeruginosa infection.
Authors: Chen SM, Cheng DS, Williams BJ, Sherrill TP, Han W, Chont M, Saint-Jean L, Christman JW, Sadikot RT, Yull FE, Blackwell TS
Clin. Exp. Immunol., 2008-07-18;0(0):.
Species: Mouse
Sample Types: BALF
-
Myeloid Src kinases regulate phagocytosis and oxidative burst in pneumococcal meningitis by activating NADPH oxidase.
Authors: Paul R, Obermaier B, Van Ziffle J, Angele B, Pfister HW, Lowell CA, Koedel U
J. Leukoc. Biol., 2008-07-14;84(4):1141-50.
Species: Mouse
Sample Types: Tissue Homogenates
-
The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.
Authors: Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M
J. Immunol., 2008-06-15;180(12):8333-41.
Species: Mouse
Sample Types: Tissue Homogenates
-
Matrix metalloproteinase-8 facilitates neutrophil migration through the corneal stromal matrix by collagen degradation and production of the chemotactic peptide Pro-Gly-Pro.
Authors: Lin M, Jackson P, Tester AM, Diaconu E, Overall CM, Blalock JE, Pearlman E
Am. J. Pathol., 2008-06-13;173(1):144-53.
Species: Mouse
Sample Types: Tissue Homogenates
-
Cytokine production by M-CSF- and GM-CSF-induced mouse bone marrow-derived macrophages upon coculturing with late apoptotic cells.
Authors: Yamazaki T, Nagata K, Kobayashi Y
Cell. Immunol., 2008-06-03;251(2):124-30.
Species: Mouse
Sample Types: Cell Culture Supernates
-
CD47 deficiency protects mice from lipopolysaccharide-induced acute lung injury and Escherichia coli pneumonia.
Authors: Su X, Johansen M, Looney MR, Brown EJ, Matthay MA
J. Immunol., 2008-05-15;180(10):6947-53.
Species: Mouse
Sample Types: BALF
-
Functional Th1 cells are required for surgical adhesion formation in a murine model.
Authors: Tzianabos AO, Holsti MA, Zheng XX, Stucchi AF, Kuchroo VK, Strom TB, Glimcher LH, Cruikshank WW
J. Immunol., 2008-05-15;180(10):6970-6.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Functional roles for C5a receptors in sepsis.
Authors: Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Kohl J, Gerard C, Sarma JV, Ward PA
Nat. Med., 2008-05-04;14(5):551-7.
Species: Mouse
Sample Types: Plasma
-
Role and regulation of adipokines during zymosan-induced peritoneal inflammation in mice.
Authors: Pini M, Gove ME, Sennello JA, van Baal JW, Chan L, Fantuzzi G
Endocrinology, 2008-05-01;149(8):4080-5.
Species: Mouse
Sample Types: Serum
-
Neutrophil-toxin interactions promote antigen delivery and mucosal clearance of Streptococcus pneumoniae.
Authors: Matthias KA, Roche AM, Standish AJ, Shchepetov M, Weiser JN
J. Immunol., 2008-05-01;180(9):6246-54.
Species: Mouse
Sample Types: Nasal Lavage Fluid
-
A novel mechanism for CCR4 in the regulation of macrophage activation in bleomycin-induced pulmonary fibrosis.
Authors: Trujillo G, O'Connor EC, Kunkel SL, Hogaboam CM
Am. J. Pathol., 2008-04-10;172(5):1209-21.
Species: Mouse
Sample Types: Tissue Homogenates
-
Effects of epithelial and neutrophil CXCR2 on innate immunity and resistance to kidney infection.
Authors: Svensson M, Irjala H, Svanborg C, Godaly G
Kidney Int., 2008-04-09;74(1):81-90.
Species: Mouse
Sample Types: Urine
-
Neutrophil chemokines KC and macrophage-inflammatory protein-2 are newly synthesized by tissue macrophages using distinct TLR signaling pathways.
Authors: De Filippo K, Henderson RB, Laschinger M, Hogg N
J. Immunol., 2008-03-15;180(6):4308-15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Matrix metalloproteinase-7 (matrilysin) controls neutrophil egress by generating chemokine gradients.
Authors: Swee M, Wilson CL, Wang Y, McGuire JK, Parks WC
J. Leukoc. Biol., 2008-03-11;83(6):1404-12.
Species: Mouse
Sample Types: Lavage Fluid
-
Adverse functions of IL-17A in experimental sepsis.
Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
FASEB J., 2008-02-25;22(7):2198-205.
Species: Mouse
Sample Types: Plasma
-
Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
Nat. Med., 2008-02-03;14(2):199-204.
Species: Mouse
Sample Types: BALF
-
Peroxisome proliferator-activated receptor-gamma ligand, 15-deoxy-Delta12,14-prostaglandin J2, reduces neutrophil migration via a nitric oxide pathway.
Authors: Napimoga MH, Vieira SM, Dal-Secco D, Freitas A, Souto FO, Mestriner FL, Alves-Filho JC, Grespan R, Kawai T, Ferreira SH, Cunha FQ
J. Immunol., 2008-01-01;180(1):609-17.
Species: Mouse
Sample Types: Tissue Secretion
-
Inflammasome-mediated production of IL-1beta is required for neutrophil recruitment against Staphylococcus aureus in vivo.
Authors: Miller LS, Pietras EM, Uricchio LH, Hirano K, Rao S, Lin H, O'Connell RM, Iwakura Y, Cheung AL, Cheng G, Modlin RL
J. Immunol., 2007-11-15;179(10):6933-42.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-17 receptor signaling influences virus-induced corneal inflammation.
Authors: Molesworth-Kenyon SJ, Yin R, Oakes JE, Lausch RN
J. Leukoc. Biol., 2007-11-12;83(2):401-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
P-selectin glycoprotein ligand-1 regulates chemokine-dependent leukocyte recruitment in colonic ischemia-reperfusion.
Authors: Santen S, Schramm R, Menger MD, Wang Y, Jeppsson B, Thorlacius H
Inflamm. Res., 2007-11-01;56(11):452-8.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
Invest. Ophthalmol. Vis. Sci., 2007-10-01;48(10):4498-508.
Species: Mouse
Sample Types: Tissue Homogenates
-
ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.
Authors: Huang X, Du W, Barrett RP, Hazlett LD
Invest. Ophthalmol. Vis. Sci., 2007-10-01;48(10):4626-33.
Species: Mouse
Sample Types: Tissue Homogenates
-
The Duffy antigen receptor for chemokines in acute renal failure: A facilitator of renal chemokine presentation.
Authors: Zarbock A, Schmolke M, Bockhorn SG, Scharte M, Buschmann K, Ley K, Singbartl K
Crit. Care Med., 2007-09-01;35(9):2156-63.
Species: Mouse
Sample Types: Tissue Homogenates
-
Keratinocyte growth factor protects against elastase-induced pulmonary emphysema in mice.
Authors: Plantier L, Marchand-Adam S, Antico VG, Boyer L, De Coster C, Marchal J, Bachoual R, Mailleux A, Boczkowski J, Crestani B
Am. J. Physiol. Lung Cell Mol. Physiol., 2007-08-31;293(5):L1230-9.
Species: Mouse
Sample Types: BALF
-
Soluble vascular endothelial growth factor receptor-1 protects mice in sepsis.
Authors: Tsao PN, Chan FT, Wei SC, Hsieh WS, Chou HC, Su YN, Chen CY, Hsu WM, Hsieh FJ, Hsu SM
Crit. Care Med., 2007-08-01;35(8):1955-60.
Species: Mouse
Sample Types: Plasma
-
Intrapulmonary delivery of bone marrow-derived mesenchymal stem cells improves survival and attenuates endotoxin-induced acute lung injury in mice.
Authors: Gupta N, Su X, Popov B, Lee JW, Serikov V, Matthay MA
J. Immunol., 2007-08-01;179(3):1855-63.
Species: Mouse
Sample Types: BALF
-
Cannabinoid-2 receptor agonist HU-308 protects against hepatic ischemia/reperfusion injury by attenuating oxidative stress, inflammatory response, and apoptosis.
Authors: Rajesh M, Pan H, Mukhopadhyay P, Batkai S, Osei-Hyiaman D, Hasko G, Liaudet L, Gao B, Pacher P
J. Leukoc. Biol., 2007-07-25;82(6):1382-9.
Species: Mouse
Sample Types: Plasma
-
Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.
Authors: Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC
Am. J. Physiol. Lung Cell Mol. Physiol., 2007-06-01;293(2):L491-6.
Species: Mouse
Sample Types: Serum
-
Toll-like receptor 4 (TLR4)-dependent proinflammatory and immunomodulatory properties of the glycoinositolphospholipid (GIPL) from Trypanosoma cruzi.
Authors: Medeiros MM, Peixoto JR, Oliveira AC, Cardilo-Reis L, Koatz VL, Van Kaer L, Previato JO, Mendonca-Previato L, Nobrega A, Bellio M
J. Leukoc. Biol., 2007-05-31;82(3):488-96.
Species: Mouse
Sample Types: Peritoneal Fluid
-
Mice lacking NKCC1 are protected from development of bacteremia and hypothermic sepsis secondary to bacterial pneumonia.
Authors: Nguyen M, Pace AJ, Koller BH
J. Exp. Med., 2007-05-21;204(6):1383-93.
Species: Mouse
Sample Types: Tissue Homogenates
-
TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways.
Authors: Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, Tobias PS, Mackman N, McKay DB
J. Immunol., 2007-05-15;178(10):6252-8.
Species: Mouse
Sample Types: Tissue Homogenates
-
CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease.
Authors: Hollingsworth JW, Li Z, Brass DM, Garantziotis S, Timberlake SH, Kim A, Hossain I, Savani RC, Schwartz DA
Am. J. Respir. Cell Mol. Biol., 2007-04-19;37(2):248-53.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Differential roles of p55 and p75 tumor necrosis factor receptors on stretch-induced pulmonary edema in mice.
Authors: Wilson MR, Goddard ME, O'Dea KP, O'Dea KP, Choudhury S, Takata M
Am. J. Physiol. Lung Cell Mol. Physiol., 2007-04-13;293(1):L60-8.
Species: Mouse
Sample Types: BALF
-
Increased inflammation delays wound healing in mice deficient in collagenase-2 (MMP-8).
Authors: Gutierrez-Fernandez A, Inada M, Balbin M, Fueyo A, Pitiot AS, Astudillo A, Hirose K, Hirata M, Shapiro SD, Noel A, Werb Z, Krane SM, Lopez-Otin C, Puente XS
FASEB J., 2007-03-28;21(10):2580-91.
Species: Mouse
Sample Types: Tissue Homogenates
-
Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
Am. J. Pathol., 2007-03-01;170(3):1003-17.
Species: Mouse
Sample Types: Serum
-
C3a is required for the production of CXC chemokines by tubular epithelial cells after renal ishemia/reperfusion.
Authors: Thurman JM, Lenderink AM, Royer PA, Coleman KE, Zhou J, Lambris JD, Nemenoff RA, Quigg RJ, Holers VM
J. Immunol., 2007-02-01;178(3):1819-28.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Cathepsin-G interferes with clearance of Pseudomonas aeruginosa from mouse lungs.
Authors: Sedor J, Hogue L, Akers K, Boslaugh S, Schreiber J, Ferkol T
Pediatr. Res., 2007-01-01;61(1):26-31.
Species: Mouse
Sample Types: BALF
-
Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection.
Authors: Gregory AD, Hogue LA, Ferkol TW, Link DC
Blood, 2006-12-21;109(8):3235-43.
Species: Mouse
Sample Types: Epithelial Fluid
-
A coagulation factor VII deficiency protects against acute inflammatory responses in mice.
Authors: Xu H, Ploplis VA, Castellino FJ
J. Pathol., 2006-12-01;210(4):488-96.
Species: Mouse
Sample Types: Plasma
-
Delayed inflammatory response to primary pneumonic plague occurs in both outbred and inbred mice.
Authors: Bubeck SS, Cantwell AM, Dube PH
Infect. Immun., 2006-11-13;75(2):697-705.
Species: Mouse
Sample Types: BALF
-
Local production of chemokines and prostaglandin E2 in the acute, chronic and recovery phase of murine experimental colitis.
Authors: Drmotova M, Rehnstrom E, Jansson L
Cytokine, 2006-11-07;35(5):275-83.
Species: Mouse
Sample Types: Tissue Homogenates
-
Delayed inflammatory responses to endotoxin in fibrinogen-deficient mice.
Authors: Cruz-Topete D, Iwaki T, Ploplis VA, Castellino FJ
J. Pathol., 2006-11-01;210(3):325-33.
Species: Mouse
Sample Types: Plasma
-
Src homology 2 domain-containing inositol 5-phosphatase 1 deficiency leads to a spontaneous allergic inflammation in the murine lung.
Authors: Oh SY, Zheng T, Bailey ML, Barber DL, Schroeder JT, Kim YK, Zhu Z
J. Allergy Clin. Immunol., 2006-10-23;119(1):123-31.
Species: Mouse
Sample Types: BALF
-
The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
Authors: Roelofs JJ, Rouschop KM, Teske GJ, Claessen N, Weening JJ, van der Poll T, Florquin S
Kidney Int., 2006-10-11;70(11):1942-7.
Species: Mouse
Sample Types: Tissue Homogenates
-
CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
Int. Immunol., 2006-09-11;18(11):1531-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
Am. J. Physiol. Lung Cell Mol. Physiol., 2006-08-04;291(6):L1246-55.
Species: Mouse
Sample Types: Tissue Homogenates
-
Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.
Authors: Kim SY, Nguyen AD, Gao JL, Murphy PM, Mansfield BC, Chou JY
J. Biol. Chem., 2006-08-04;281(39):28794-801.
Species: Mouse
Sample Types: Plasma
-
The transcriptional response to lipopolysaccharide reveals a role for interferon-gamma in lung neutrophil recruitment.
Authors: Burch LH, Yang IV, Whitehead GS, Chao FG, Berman KG, Schwartz DA
Am. J. Physiol. Lung Cell Mol. Physiol., 2006-06-09;291(4):L677-82.
Species: Mouse
Sample Types: BALF
-
The macrophage scavenger receptor SR-AI/II and lung defense against pneumococci and particles.
Authors: Arredouani MS, Yang Z, Imrich A, Ning Y, Qin G, Kobzik L
Am. J. Respir. Cell Mol. Biol., 2006-05-04;35(4):474-8.
Species: Mouse
Sample Types: BALF
-
Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis.
Authors: Nemeth ZH, Csoka B, Wilmanski J, Xu D, Lu Q, Ledent C, Deitch EA, Pacher P, Spolarics Z, Hasko G
J. Immunol., 2006-05-01;176(9):5616-26.
Species: Mouse
Sample Types: Plasma
-
High expression of ligands for chemokine receptor CXCR2 in alveolar epithelial neoplasia induced by oncogenic kras.
Authors: Wislez M, Fujimoto N, Izzo JG, Hanna AE, Cody DD, Langley RR, Tang H, Burdick MD, Sato M, Minna JD, Mao L, Wistuba I, Strieter RM, Kurie JM
Cancer Res., 2006-04-15;66(8):4198-207.
Species: Mouse
Sample Types: Tissue Homogenates
-
Human CXCR2 (hCXCR2) takes over functionalities of its murine homolog in hCXCR2 knockin mice.
Authors: Mihara K, Smit MJ, Krajnc-Franken M, Gossen J, Rooseboom M, Dokter W
Eur. J. Immunol., 2005-09-01;35(9):2573-82.
Species: Mouse
Sample Types: Serum
-
Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation.
Authors: Sergejeva S, Ivanov S, Lotvall J, Linden A
Am. J. Respir. Cell Mol. Biol., 2005-05-18;33(3):248-53.
Species: Mouse
Sample Types: BALF
-
Endogenous interleukin-12 improves the early antimicrobial host response to murine Escherichia coli peritonitis.
Authors: Weijer S, Florquin S, van der Poll T
Shock, 2005-01-01;23(1):54-8.
Species: Mouse
Sample Types: Peritoneal Fluid
-
The class A macrophage scavenger receptor attenuates CXC chemokine production and the early infiltration of neutrophils in sterile peritonitis.
Authors: Cotena A, Platt N
J. Immunol., 2004-11-15;173(10):6427-32.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
Authors: Thakur A, Barrett RP, McClellan S, Hazlett LD
Curr. Eye Res., 2004-10-01;29(4):225-33.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-22 increases the innate immunity of tissues.
Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
Immunity, 2004-08-01;21(2):241-54.
Species: Mouse
Sample Types: Plasma
-
T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
J. Exp. Med., 2004-05-17;199(10):1355-65.
Species: Mouse
Sample Types: Serum
-
Circulating CXC-chemokine concentrations in a murine intestinal ischemia-reperfusion model.
Authors: Maheshwari A, Christensen RD, Calhoun DA
Fetal Pediatr Pathol, 2004-03-01;23(2):145-57.
Species: Mouse
Sample Types: Serum
-
Transcription regulation of TNF-alpha-early response genes by poly(ADP-ribose) polymerase-1 in murine heart endothelial cells.
Authors: Carrillo A, Monreal Y, Ramirez P, Marin L, Parrilla P, Oliver FJ, Yelamos J
Nucleic Acids Res., 2004-02-03;32(2):757-66.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Chemokine and cytokine production during Orientia tsutsugamushi infection in mice.
Authors: Koh YS, Yun JH, Seong SY, Choi MS, Kim IS
Microb. Pathog., 2004-01-01;36(1):51-7.
Species: Mouse
Sample Types: Peritoneal Fluid
-
CD40 plays a crucial role in lipopolysaccharide-induced acute lung injury.
Authors: Hashimoto N, Kawabe T, Imaizumi K, Hara T, Okamoto M, Kojima K, Shimokata K, Hasegawa Y
Am. J. Respir. Cell Mol. Biol., 2003-12-23;30(6):808-15.
Species: Mouse
Sample Types: BALF
-
Thrombomodulin mutant mice with a strongly reduced capacity to generate activated protein C have an unaltered pulmonary immune response to respiratory pathogens and lipopolysaccharide.
Authors: Rijneveld AW, Weijer S, Florquin S, Esmon CT, Meijers JC, Speelman P, Reitsma PH, ten Cate H, van der Poll T
Blood, 2003-10-30;103(5):1702-9.
Species: Mouse
Sample Types: BALF
-
Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways.
Authors: Miyamoto M, Prause O, Sjostrand M, Laan M, Lotvall J, Linden A
J. Immunol., 2003-05-01;170(9):4665-72.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Interleukin-10 negatively regulates local cytokine and chemokine production but does not influence antibacterial host defense during murine pneumococcal meningitis.
Authors: Zwijnenburg PJ, van der Poll T, Florquin S, Roord JJ, van Furth AM
Infect. Immun., 2003-04-01;71(4):2276-9.
Species: Mouse
Sample Types: Tissue Homogenates
-
IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger.
Authors: Ferretti S, Bonneau O, Dubois GR, Jones CE, Trifilieff A
J. Immunol., 2003-02-15;170(4):2106-12.
Species: Mouse
Sample Types: BALF
-
Selective I kappa B kinase expression in airway epithelium generates neutrophilic lung inflammation.
Authors: Sadikot RT, Han W, Everhart MB, Zoia O, Peebles RS, Jansen ED, Yull FE, Christman JW, Blackwell TS
J. Immunol., 2003-01-15;170(2):1091-8.
Species: Mouse
Sample Types: BALF
-
Resident cell chemokine expression serves as the major mechanism for leukocyte recruitment during local inflammation.
Authors: Garcia-Ramallo E, Marques T, Prats N, Beleta J, Kunkel SL, Godessart N
J. Immunol., 2002-12-01;169(11):6467-73.
Species: Mouse
Sample Types: Air Pouch Exudate
-
Cutting edge: myeloid differentiation factor 88 deficiency improves resistance against sepsis caused by polymicrobial infection.
Authors: Weighardt H, Bê Ë„Æ%í, Kaiser-Moore S, Vabulas RM, Kirschning CJ, Wagner H, Holzmann B
2002-09-15;169(6):2823-7.
Species: Mouse
Sample Types: Serum
-
Neutrophil-mediated mycobacteriocidal immunity in the lung during Mycobacterium bovis BCG infection in C57BL/6 mice.
Authors: Fulton SA, Reba SM, Martin TD, Boom WH
Infect. Immun., 2002-09-01;70(9):5322-7.
Species: Mouse
Sample Types: BALF
-
Overexpression of extracellular superoxide dismutase decreases lung injury after exposure to oil fly ash.
Authors: Ghio AJ, 107303, Suliman HB, Carter JD, Abushamaa AM, Folz RJ
MiR-99a alleviates apoptosis and extracellular matrix degradation in experimentally induced spine osteoarthritis by targeting FZD8, 2002-07-01;283(1):L211-8.
Species: Mouse
Sample Types: Tracheal Lavage Fluid
-
Requirement of interleukin 17 receptor signaling for lung CXC chemokine and granulocyte colony-stimulating factor expression, neutrophil recruitment, and host defense.
Authors: Ye P, Rodriguez FH, Kanaly S, Stocking KL, Schurr J, Schwarzenberger P, Oliver P, Huang W, Zhang P, Zhang J, Shellito JE, Bagby GJ, Nelson S, Charrier K, Peschon JJ, Kolls JK
J. Exp. Med., 2001-08-20;194(4):519-27.
Species: Mouse
Sample Types: BALF
-
The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
Eur. J. Immunol., 2001-07-01;31(7):2104-15.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Il-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation.
Authors: Hurst SM, Wilkinson TS, McLoughlin RM, Jones S, Horiuchi S, Yamamoto N, Rose-John S, Fuller GM, Topley N, Jones SA
Immunity, 2001-06-01;14(6):705-14.
Species: Mouse
Sample Types: Peritoneal Lavage Fluid
-
Rapid up-regulation of CXC chemokines in the airways after Ag-specific CD4+ T cell activation.
Authors: Knott PG, Gater PR, Dunford PJ, Fuentes ME, Bertrand CP
J. Immunol., 2001-01-15;166(2):1233-40.
Species: Mouse
Sample Types: Cell Culture Supernates
-
Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression.
Authors: Medvedev AE, Kopydlowski KM, Vogel SN
J. Immunol., 2000-06-01;164(11):5564-74.
Species: Mouse
Sample Types: Cell Culture Supernates
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Result has been published in 10.1371/journal.pone.0058258