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KRpep-2d

Catalog #: 7928 Datasheet / COA / SDS

Discontinued Product

7928 has been discontinued.
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KRpep-2d
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Description: Potent and selective KRASG12D inhibitor

Purity: ≥95%

Product Details
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Biological Activity

KRpep-2d is a potent KRAS inhibitor. Selective for G12D mutant KRAS over wild type KRAS (IC50 = 1.6 nM and 42 nM respectively). Allosterically binds to KRAS to block interaction with substrate, such as GDP. Cell permeable and suitable for use in vitro.

Technical Data

M.Wt:
2561.03
Formula:
C108H182N44O25S2
Sequence:
RRRRCPLYISYDPVCRRRR

(Modifications: Arg-1 = N-terminal Ac, Disulfide bridge: 5-15, Arg-19 = C-terminal amide)

Solubility:
Soluble to 2 mg/ml in water
Purity:
≥95%
Storage:
Store at -20°C
CAS No:
2098181-84-9

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
Tocris products are intended for laboratory research use only, unless stated otherwise.

Product Datasheets

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